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Showing 1 to 12 of 73 entries
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Environmental effects on fractional exhaled nitric oxide in allergic children.

Journal of allergy

La Grutta S, Ferrante G, Malizia V, Cibella F, Viegi G.
PMID: 22162708
J Allergy (Cairo). 2012;2012:916926. doi: 10.1155/2012/916926. Epub 2011 Nov 17.

Fractional exhaled nitric oxide (FeNO) is a non-invasive marker of airway inflammation in asthma and respiratory allergy. Environmental factors, especially indoor and outdoor air quality, may play an important role in triggering acute exacerbations of respiratory symptoms. The authors...

Lights and shadows of cardiac magnetic resonance imaging in acute myocarditis.

Insights into imaging

Esposito A, Francone M, Faletti R, Centonze M, Cademartiri F, Carbone I, De Rosa R, Di Cesare E, La Grutta L, Ligabue G, Lovato L, Maffei E, Marano R, Midiri M, Pontone G, Natale L, De Cobelli F.
PMID: 26555392
Insights Imaging. 2016 Feb;7(1):99-110. doi: 10.1007/s13244-015-0444-7. Epub 2015 Nov 10.

UNLABELLED: Cardiac magnetic resonance (CMR) is considered a primary tool for the diagnosis of acute myocarditis, due to its unique potential for non-invasive identification of the various hallmarks of the inflammatory response, with relevant impact on patient management and...

Myocardial blood flow quantification for evaluation of coronary artery disease by computed tomography.

Cardiovascular diagnosis and therapy

Cademartiri F, Seitun S, Clemente A, La Grutta L, Toia P, Runza G, Midiri M, Maffei E.
PMID: 28540209
Cardiovasc Diagn Ther. 2017 Apr;7(2):129-150. doi: 10.21037/cdt.2017.03.22.

During the last decade coronary computed tomography angiography (CTA) has become the preeminent non-invasive imaging modality to detect coronary artery disease (CAD) with high accuracy. However, CTA has a limited value in assessing the hemodynamic significance of a given...

Induction of oxidative stress in human aqueous and vitreous humors by Nd:YAG laser posterior capsulotomy.

International journal of ophthalmology

Bergandi L, Skorokhod OA, Franzone F, La Grotta R, Schwarzer E, Nuzzi R.
PMID: 30046531
Int J Ophthalmol. 2018 Jul 18;11(7):1145-1151. doi: 10.18240/ijo.2018.07.12. eCollection 2018.

AIM: To evaluate whether the Q-switched Nd:YAG laser treatment applied in routine capsulotomy elicits oxidative stress in aqueous and vitreous humors.METHODS: Thirty-six patients who had to undergo a 25 gauge pars plana vitrectomy due to vitreoretinal disorders were enrolled,...

Effect of time and titer in convalescent plasma therapy for COVID-19.

iScience

de Candia P, Prattichizzo F, Garavelli S, La Grotta R, De Rosa A, Pontarelli A, Parrella R, Ceriello A, Matarese G.
PMID: 34316549
iScience. 2021 Aug 20;24(8):102898. doi: 10.1016/j.isci.2021.102898. Epub 2021 Jul 22.

The clinical benefit of convalescent plasma (CP) for patients with coronavirus disease (COVID)-19 is still debated. In this systematic review and meta-analysis, we selected 10 randomized clinical trials (RCTs) and 15 non-randomized studies (total number of patients = 22,591)...

Association between Asthma Control and Exposure to Greenness and Other Outdoor and Indoor Environmental Factors: A Longitudinal Study on a Cohort of Asthmatic Children.

International journal of environmental research and public health

Cilluffo G, Ferrante G, Fasola S, Malizia V, Montalbano L, Ranzi A, Badaloni C, Viegi G, La Grutta S.
PMID: 35010773
Int J Environ Res Public Health. 2022 Jan 04;19(1). doi: 10.3390/ijerph19010512.

Achieving and maintaining asthma control (AC) is the main goal of asthma management. Indoor and outdoor environmental factors may play an important role on AC. The aim of this longitudinal study was to evaluate the association between AC and...

A Critical Review of Statistical Methods for Twin Studies Relating Exposure to Early Life Health Conditions.

International journal of environmental research and public health

Fasola S, Montalbano L, Cilluffo G, Cuer B, Malizia V, Ferrante G, Annesi-Maesano I, La Grutta S.
PMID: 34886424
Int J Environ Res Public Health. 2021 Dec 02;18(23). doi: 10.3390/ijerph182312696.

When investigating disease etiology, twin data provide a unique opportunity to control for confounding and disentangling the role of the human genome and exposome. However, using appropriate statistical methods is fundamental for exploiting such potential. We aimed to critically...

Technical development in cardiac CT: current standards and future improvements-a narrative review.

Cardiovascular diagnosis and therapy

Toia P, La Grutta L, Sollami G, Clemente A, Gagliardo C, Galia M, Maffei E, Midiri M, Cademartiri F.
PMID: 33381441
Cardiovasc Diagn Ther. 2020 Dec;10(6):2018-2035. doi: 10.21037/cdt-20-527.

Non-invasive depiction of coronary arteries has been a great challenge for imaging specialists since the introduction of computed tomography (CT). Technological development together with improvements in spatial, temporal, and contrast resolution, progressively allowed implementation of the current clinical role...

Machine Learning: An Overview and Applications in Pharmacogenetics.

Genes

Cilluffo G, Fasola S, Ferrante G, Malizia V, Montalbano L, La Grutta S.
PMID: 34680905
Genes (Basel). 2021 Sep 26;12(10). doi: 10.3390/genes12101511.

This narrative review aims to provide an overview of the main Machine Learning (ML) techniques and their applications in pharmacogenetics (such as antidepressant, anti-cancer and warfarin drugs) over the past 10 years. ML deals with the study, the design...

HiPSC-CMs from different sex and ethnic origin donors exhibit qualitatively different responses to several classes of pharmacological challenges.

Journal of pharmacological and toxicological methods

Zeng H, Wang J, Clouse H, Lagrutta A, Sannajust F.
PMID: 31201864
J Pharmacol Toxicol Methods. 2019 Sep - Oct;99:106598. doi: 10.1016/j.vascn.2019.106598. Epub 2019 Jun 12.

We investigated whether human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) created from diverse origins could have qualitatively (not just quantitatively) different responses to pharmacological reagents. Specifically, we challenged six hiPSC-CM syncytia made from a female Caucasian, a female black...

Effects of E-Cigarette Exposure on Prenatal Life and Childhood Respiratory Health: A Review of Current Evidence.

Frontiers in pediatrics

Mescolo F, Ferrante G, La Grutta S.
PMID: 34513764
Front Pediatr. 2021 Aug 20;9:711573. doi: 10.3389/fped.2021.711573. eCollection 2021.

In the last decade, widespread use of E-cigarettes (EC) has occurred all over the world. Whereas, a large amount of evidence on harm to children from conventional cigarette exposure is available, data on health effects in this population throughout...

DNA Methylation in Nasal Epithelium: Strengths and Limitations of an Emergent Biomarker for Childhood Asthma.

Frontiers in pediatrics

Solazzo G, Ferrante G, La Grutta S.
PMID: 32500051
Front Pediatr. 2020 May 15;8:256. doi: 10.3389/fped.2020.00256. eCollection 2020.

Asthma is one of the most widespread chronic respiratory conditions. This disease primarily develops in childhood and is influenced by different factors, mainly genetics and environmental factors. DNA methylation is an epigenetic mechanism which may represent a bridge between...

Showing 1 to 12 of 73 entries