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Hypoxia-induced Haem Oxygenase-1 gene expression in neonatal rat cardiac myocytes.

Heart, lung & circulation

Long X, Wu G, Rozanski DJ, Boluyt MO, Crow MT, Lakatta EG.
PMID: 16352050
Heart Lung Circ. 2001;10(3):121-9. doi: 10.1046/j.1444-2892.2001.00100.x.

BACKGROUND: Haem oxygenase (HO-1), a heat shock or stress protein, is a rate-limiting enzyme in the conversion of pro-oxidant haem to biliverdin and carbon monoxide (CO). The products of haem catabolism serve regulatory and protective functions. Previous studies have...

Cite
Long X, Wu G, Rozanski DJ, et al. Hypoxia-induced Haem Oxygenase-1 gene expression in neonatal rat cardiac myocytes. Heart Lung Circ. 2001;10(3):121-9doi: 10.1046/j.1444-2892.2001.00100.x.
Long, X., Wu, G., Rozanski, D. J., Boluyt, M. O., Crow, M. T., & Lakatta, E. G. (2001). Hypoxia-induced Haem Oxygenase-1 gene expression in neonatal rat cardiac myocytes. Heart, lung & circulation, 10(3), 121-9. https://doi.org/10.1046/j.1444-2892.2001.00100.x
Long, X, et al. "Hypoxia-induced Haem Oxygenase-1 gene expression in neonatal rat cardiac myocytes." Heart, lung & circulation vol. 10,3 (2001): 121-9. doi: https://doi.org/10.1046/j.1444-2892.2001.00100.x
Long X, Wu G, Rozanski DJ, Boluyt MO, Crow MT, Lakatta EG. Hypoxia-induced Haem Oxygenase-1 gene expression in neonatal rat cardiac myocytes. Heart Lung Circ. 2001;10(3):121-9. doi: 10.1046/j.1444-2892.2001.00100.x. PMID: 16352050.
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Central Arterial Aging and Angiotensin II Signaling.

Current hypertension reviews

Wang M, Khazan B, Lakatta EG.
PMID: 21423831
Curr Hypertens Rev. 2010 Nov 01;6(4):266-281. doi: 10.2174/157340210793611668.

Arterial remodeling over time is a cornerstone of normal systemic aging. The age-associated arterial structural and functional changes in the intima, the media, and the adventitia are closely linked to angiotensin II (Ang II) signaling. A growing line of...

Cite
Wang M, Khazan B, Lakatta EG. Central Arterial Aging and Angiotensin II Signaling. Curr Hypertens Rev. 2010;6(4):266-281doi: 10.2174/157340210793611668.
Wang, M., Khazan, B., & Lakatta, E. G. (2010). Central Arterial Aging and Angiotensin II Signaling. Current hypertension reviews, 6(4), 266-281. https://doi.org/10.2174/157340210793611668
Wang, Mingyi, et al. "Central Arterial Aging and Angiotensin II Signaling." Current hypertension reviews vol. 6,4 (2010): 266-281. doi: https://doi.org/10.2174/157340210793611668
Wang M, Khazan B, Lakatta EG. Central Arterial Aging and Angiotensin II Signaling. Curr Hypertens Rev. 2010 Nov 01;6(4):266-281. doi: 10.2174/157340210793611668. PMID: 21423831; PMCID: PMC3058527.
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Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Nature genetics

Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, Karaman I, Ng FL, Evangelou M, Witkowska K, Tzanis E, Hellwege JN, Giri A, Velez Edwards DR, Sun YV, Cho K, Gaziano JM, Wilson PWF, Tsao PS, Kovesdy CP, Esko T, Mägi R, Milani L, Almgren P, Boutin T, Debette S, Ding J, Giulianini F, Holliday EG, Jackson AU, Li-Gao R, Lin WY, Luan J, Mangino M, Oldmeadow C, Prins BP, Qian Y, Sargurupremraj M, Shah N, Surendran P, Thériault S, Verweij N, Willems SM, Zhao JH, Amouyel P, Connell J, de Mutsert R, Doney ASF, Farrall M, Menni C, Morris AD, Noordam R, Paré G, Poulter NR, Shields DC, Stanton A, Thom S, Abecasis G, Amin N, Arking DE, Ayers KL, Barbieri CM, Batini C, Bis JC, Blake T, Bochud M, Boehnke M, Boerwinkle E, Boomsma DI, Bottinger EP, Braund PS, Brumat M, Campbell A, Campbell H, Chakravarti A, Chambers JC, Chauhan G, Ciullo M, Cocca M, Collins F, Cordell HJ, Davies G, de Borst MH, de Geus EJ, Deary IJ, Deelen J, Del Greco M F, Demirkale CY, Dörr M, Ehret GB, Elosua R, Enroth S, Erzurumluoglu AM, Ferreira T, Frånberg M, Franco OH, Gandin I, Gasparini P, Giedraitis V, Gieger C, Girotto G, Goel A, Gow AJ, Gudnason V, Guo X, Gyllensten U, Hamsten A, Harris TB, Harris SE, Hartman CA, Havulinna AS, Hicks AA, Hofer E, Hofman A, Hottenga JJ, Huffman JE, Hwang SJ, Ingelsson E, James A, Jansen R, Jarvelin MR, Joehanes R, Johansson Å, Johnson AD, Joshi PK, Jousilahti P, Jukema JW, Jula A, Kähönen M, Kathiresan S, Keavney BD, Khaw KT, Knekt P, Knight J, Kolcic I, Kooner JS, Koskinen S, Kristiansson K, Kutalik Z, Laan M, Larson M, Launer LJ, Lehne B, Lehtimäki T, Liewald DCM, Lin L, Lind L, Lindgren CM, Liu Y, Loos RJF, Lopez LM, Lu Y, Lyytikäinen LP, Mahajan A, Mamasoula C, Marrugat J, Marten J, Milaneschi Y, Morgan A, Morris AP, Morrison AC, Munson PJ, Nalls MA, Nandakumar P, Nelson CP, Niiranen T, Nolte IM, Nutile T, Oldehinkel AJ, Oostra BA, O'Reilly PF, Org E, Padmanabhan S, Palmas W, Palotie A, Pattie A, Penninx BWJH, Perola M, Peters A, Polasek O, Pramstaller PP, Nguyen QT, Raitakari OT, Ren M, Rettig R, Rice K, Ridker PM, Ried JS, Riese H, Ripatti S, Robino A, Rose LM, Rotter JI, Rudan I, Ruggiero D, Saba Y, Sala CF, Salomaa V, Samani NJ, Sarin AP, Schmidt R, Schmidt H, Shrine N, Siscovick D, Smith AV, Snieder H, Sõber S, Sorice R, Starr JM, Stott DJ, Strachan DP, Strawbridge RJ, Sundström J, Swertz MA, Taylor KD, Teumer A, Tobin MD, Tomaszewski M, Toniolo D, Traglia M, Trompet S, Tuomilehto J, Tzourio C, Uitterlinden AG, Vaez A, van der Most PJ, van Duijn CM, Vergnaud AC, Verwoert GC, Vitart V, Völker U, Vollenweider P, Vuckovic D, Watkins H, Wild SH, Willemsen G, Wilson JF, Wright AF, Yao J, Zemunik T, Zhang W, Attia JR, Butterworth AS, Chasman DI, Conen D, Cucca F, Danesh J, Hayward C, Howson JMM, Laakso M, Lakatta EG, Langenberg C, Melander O, Mook-Kanamori DO, Palmer CNA, Risch L, Scott RA, Scott RJ, Sever P, Spector TD, van der Harst P, Wareham NJ, Zeggini E, Levy D, Munroe PB, Newton-Cheh C, Brown MJ, Metspalu A, Hung AM, O'Donnell CJ, Edwards TL, Psaty BM, Tzoulaki I, Barnes MR, Wain LV, Elliott P, Caulfield MJ.
PMID: 30429575
Nat Genet. 2018 Dec;50(12):1755. doi: 10.1038/s41588-018-0297-3.

In the version of this article originally published, the name of author Martin H. de Borst was coded incorrectly in the XML. The error has now been corrected in the HTML version of the paper.

Cite
Evangelou E, Warren HR, Mosen-Ansorena D, et al. Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nat Genet. 2018;50(12):1755doi: 10.1038/s41588-018-0297-3.
Evangelou, E., Warren, H. R., Mosen-Ansorena, D., Mifsud, B., Pazoki, R., Gao, H., Ntritsos, G., Dimou, N., Cabrera, C. P., Karaman, I., Ng, F. L., Evangelou, M., Witkowska, K., Tzanis, E., Hellwege, J. N., Giri, A., Velez Edwards, D. R., Sun, Y. V., Cho, K., Gaziano, J. M., Wilson, P. W. F., Tsao, P. S., Kovesdy, C. P., Esko, T., Mägi, R., Milani, L., Almgren, P., Boutin, T., Debette, S., Ding, J., Giulianini, F., Holliday, E. G., Jackson, A. U., Li-Gao, R., Lin, W. Y., Luan, J., Mangino, M., Oldmeadow, C., Prins, B. P., Qian, Y., Sargurupremraj, M., Shah, N., Surendran, P., Thériault, S., Verweij, N., Willems, S. M., Zhao, J. H., Amouyel, P., Connell, J., de Mutsert, R., Doney, A. S. F., Farrall, M., Menni, C., Morris, A. D., Noordam, R., Paré, G., Poulter, N. R., Shields, D. C., Stanton, A., Thom, S., Abecasis, G., Amin, N., Arking, D. E., Ayers, K. L., Barbieri, C. M., Batini, C., Bis, J. C., Blake, T., Bochud, M., Boehnke, M., Boerwinkle, E., Boomsma, D. I., Bottinger, E. P., Braund, P. S., Brumat, M., Campbell, A., Campbell, H., Chakravarti, A., Chambers, J. C., Chauhan, G., Ciullo, M., Cocca, M., Collins, F., Cordell, H. J., Davies, G., de Borst, M. H., de Geus, E. J., Deary, I. J., Deelen, J., Del Greco M, F., Demirkale, C. Y., Dörr, M., Ehret, G. B., Elosua, R., Enroth, S., Erzurumluoglu, A. M., Ferreira, T., Frånberg, M., Franco, O. H., Gandin, I., Gasparini, P., Giedraitis, V., Gieger, C., Girotto, G., Goel, A., Gow, A. J., Gudnason, V., Guo, X., Gyllensten, U., Hamsten, A., Harris, T. B., Harris, S. E., Hartman, C. A., Havulinna, A. S., Hicks, A. A., Hofer, E., Hofman, A., Hottenga, J. J., Huffman, J. E., Hwang, S. J., Ingelsson, E., James, A., Jansen, R., Jarvelin, M. R., Joehanes, R., Johansson, �. �., Johnson, A. D., Joshi, P. K., Jousilahti, P., Jukema, J. W., Jula, A., Kähönen, M., Kathiresan, S., Keavney, B. D., Khaw, K. T., Knekt, P., Knight, J., Kolcic, I., Kooner, J. S., Koskinen, S., Kristiansson, K., Kutalik, Z., Laan, M., Larson, M., Launer, L. J., Lehne, B., Lehtimäki, T., Liewald, D. C. M., Lin, L., Lind, L., Lindgren, C. M., Liu, Y., Loos, R. J. F., Lopez, L. M., Lu, Y., Lyytikäinen, L. P., Mahajan, A., Mamasoula, C., Marrugat, J., Marten, J., Milaneschi, Y., Morgan, A., Morris, A. P., Morrison, A. C., Munson, P. J., Nalls, M. A., Nandakumar, P., Nelson, C. P., Niiranen, T., Nolte, I. M., Nutile, T., Oldehinkel, A. J., Oostra, B. A., O'Reilly, P. F., Org, E., Padmanabhan, S., Palmas, W., Palotie, A., Pattie, A., Penninx, B. W. J. H., Perola, M., Peters, A., Polasek, O., Pramstaller, P. P., Nguyen, Q. T., Raitakari, O. T., Ren, M., Rettig, R., Rice, K., Ridker, P. M., Ried, J. S., Riese, H., Ripatti, S., Robino, A., Rose, L. M., Rotter, J. I., Rudan, I., Ruggiero, D., Saba, Y., Sala, C. F., Salomaa, V., Samani, N. J., Sarin, A. P., Schmidt, R., Schmidt, H., Shrine, N., Siscovick, D., Smith, A. V., Snieder, H., Sõber, S., Sorice, R., Starr, J. M., Stott, D. J., Strachan, D. P., Strawbridge, R. J., Sundström, J., Swertz, M. A., Taylor, K. D., Teumer, A., Tobin, M. D., Tomaszewski, M., Toniolo, D., Traglia, M., Trompet, S., Tuomilehto, J., Tzourio, C., Uitterlinden, A. G., Vaez, A., van der Most, P. J., van Duijn, C. M., Vergnaud, A. C., Verwoert, G. C., Vitart, V., Völker, U., Vollenweider, P., Vuckovic, D., Watkins, H., Wild, S. H., Willemsen, G., Wilson, J. F., Wright, A. F., Yao, J., Zemunik, T., Zhang, W., Attia, J. R., Butterworth, A. S., Chasman, D. I., Conen, D., Cucca, F., Danesh, J., Hayward, C., Howson, J. M. M., Laakso, M., Lakatta, E. G., Langenberg, C., Melander, O., Mook-Kanamori, D. O., Palmer, C. N. A., Risch, L., Scott, R. A., Scott, R. J., Sever, P., Spector, T. D., van der Harst, P., Wareham, N. J., Zeggini, E., Levy, D., Munroe, P. B., Newton-Cheh, C., Brown, M. J., Metspalu, A., Hung, A. M., O'Donnell, C. J., Edwards, T. L., Psaty, B. M., Tzoulaki, I., Barnes, M. R., Wain, L. V., Elliott, P., & Caulfield, M. J. (2018). Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nature genetics, 50(12), 1755. https://doi.org/10.1038/s41588-018-0297-3
Evangelou, Evangelos, et al. "Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits." Nature genetics vol. 50,12 (2018): 1755. doi: https://doi.org/10.1038/s41588-018-0297-3
Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, Karaman I, Ng FL, Evangelou M, Witkowska K, Tzanis E, Hellwege JN, Giri A, Velez Edwards DR, Sun YV, Cho K, Gaziano JM, Wilson PWF, Tsao PS, Kovesdy CP, Esko T, Mägi R, Milani L, Almgren P, Boutin T, Debette S, Ding J, Giulianini F, Holliday EG, Jackson AU, Li-Gao R, Lin WY, Luan J, Mangino M, Oldmeadow C, Prins BP, Qian Y, Sargurupremraj M, Shah N, Surendran P, Thériault S, Verweij N, Willems SM, Zhao JH, Amouyel P, Connell J, de Mutsert R, Doney ASF, Farrall M, Menni C, Morris AD, Noordam R, Paré G, Poulter NR, Shields DC, Stanton A, Thom S, Abecasis G, Amin N, Arking DE, Ayers KL, Barbieri CM, Batini C, Bis JC, Blake T, Bochud M, Boehnke M, Boerwinkle E, Boomsma DI, Bottinger EP, Braund PS, Brumat M, Campbell A, Campbell H, Chakravarti A, Chambers JC, Chauhan G, Ciullo M, Cocca M, Collins F, Cordell HJ, Davies G, de Borst MH, de Geus EJ, Deary IJ, Deelen J, Del Greco M F, Demirkale CY, Dörr M, Ehret GB, Elosua R, Enroth S, Erzurumluoglu AM, Ferreira T, Frånberg M, Franco OH, Gandin I, Gasparini P, Giedraitis V, Gieger C, Girotto G, Goel A, Gow AJ, Gudnason V, Guo X, Gyllensten U, Hamsten A, Harris TB, Harris SE, Hartman CA, Havulinna AS, Hicks AA, Hofer E, Hofman A, Hottenga JJ, Huffman JE, Hwang SJ, Ingelsson E, James A, Jansen R, Jarvelin MR, Joehanes R, Johansson Å, Johnson AD, Joshi PK, Jousilahti P, Jukema JW, Jula A, Kähönen M, Kathiresan S, Keavney BD, Khaw KT, Knekt P, Knight J, Kolcic I, Kooner JS, Koskinen S, Kristiansson K, Kutalik Z, Laan M, Larson M, Launer LJ, Lehne B, Lehtimäki T, Liewald DCM, Lin L, Lind L, Lindgren CM, Liu Y, Loos RJF, Lopez LM, Lu Y, Lyytikäinen LP, Mahajan A, Mamasoula C, Marrugat J, Marten J, Milaneschi Y, Morgan A, Morris AP, Morrison AC, Munson PJ, Nalls MA, Nandakumar P, Nelson CP, Niiranen T, Nolte IM, Nutile T, Oldehinkel AJ, Oostra BA, O'Reilly PF, Org E, Padmanabhan S, Palmas W, Palotie A, Pattie A, Penninx BWJH, Perola M, Peters A, Polasek O, Pramstaller PP, Nguyen QT, Raitakari OT, Ren M, Rettig R, Rice K, Ridker PM, Ried JS, Riese H, Ripatti S, Robino A, Rose LM, Rotter JI, Rudan I, Ruggiero D, Saba Y, Sala CF, Salomaa V, Samani NJ, Sarin AP, Schmidt R, Schmidt H, Shrine N, Siscovick D, Smith AV, Snieder H, Sõber S, Sorice R, Starr JM, Stott DJ, Strachan DP, Strawbridge RJ, Sundström J, Swertz MA, Taylor KD, Teumer A, Tobin MD, Tomaszewski M, Toniolo D, Traglia M, Trompet S, Tuomilehto J, Tzourio C, Uitterlinden AG, Vaez A, van der Most PJ, van Duijn CM, Vergnaud AC, Verwoert GC, Vitart V, Völker U, Vollenweider P, Vuckovic D, Watkins H, Wild SH, Willemsen G, Wilson JF, Wright AF, Yao J, Zemunik T, Zhang W, Attia JR, Butterworth AS, Chasman DI, Conen D, Cucca F, Danesh J, Hayward C, Howson JMM, Laakso M, Lakatta EG, Langenberg C, Melander O, Mook-Kanamori DO, Palmer CNA, Risch L, Scott RA, Scott RJ, Sever P, Spector TD, van der Harst P, Wareham NJ, Zeggini E, Levy D, Munroe PB, Newton-Cheh C, Brown MJ, Metspalu A, Hung AM, O'Donnell CJ, Edwards TL, Psaty BM, Tzoulaki I, Barnes MR, Wain LV, Elliott P, Caulfield MJ. Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nat Genet. 2018 Dec;50(12):1755. doi: 10.1038/s41588-018-0297-3. PMID: 30429575.
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Carotid Beta Stiffness Association with Thyroid Function.

Journal of clinical medicine

Delitala AP, Scuteri A, Fiorillo E, Orrù V, Lakatta EG, Schlessinger D, Cucca F.
PMID: 33499200
J Clin Med. 2021 Jan 22;10(3). doi: 10.3390/jcm10030420.

BACKGROUND: Thyroid hormone modulation of cardiovascular function has been associated with cardiovascular disease. Recent evidence suggests that free thyroxine (FT4) levels are associated with an increase in systemic arterial stiffness, but little is known about the effects of FT4...

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Delitala AP, Scuteri A, Fiorillo E, et al. Carotid Beta Stiffness Association with Thyroid Function. J Clin Med. 2021;10(3)doi: 10.3390/jcm10030420.
Delitala, A. P., Scuteri, A., Fiorillo, E., Orrù, V., Lakatta, E. G., Schlessinger, D., & Cucca, F. (2021). Carotid Beta Stiffness Association with Thyroid Function. Journal of clinical medicine, 10(3), . https://doi.org/10.3390/jcm10030420
Delitala, Alessandro P, et al. "Carotid Beta Stiffness Association with Thyroid Function." Journal of clinical medicine vol. 10,3 (2021). doi: https://doi.org/10.3390/jcm10030420
Delitala AP, Scuteri A, Fiorillo E, Orrù V, Lakatta EG, Schlessinger D, Cucca F. Carotid Beta Stiffness Association with Thyroid Function. J Clin Med. 2021 Jan 22;10(3). doi: 10.3390/jcm10030420. PMID: 33499200; PMCID: PMC7865481.
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Mitochondrial health is enhanced in rats with higher vs. lower intrinsic exercise capacity and extended lifespan.

NPJ aging and mechanisms of disease

Aon MA, Cortassa S, Juhaszova M, González-Reyes JA, Calvo-Rubio M, Villalba JM, Lachance AD, Ziman BD, Mitchell SJ, Murt KN, Axsom JEC, Alfaras I, Britton SL, Koch LG, de Cabo R, Lakatta EG, Sollott SJ.
PMID: 33398019
NPJ Aging Mech Dis. 2021 Jan 04;7(1):1. doi: 10.1038/s41514-020-00054-3.

The intrinsic aerobic capacity of an organism is thought to play a role in aging and longevity. Maximal respiratory rate capacity, a metabolic performance measure, is one of the best predictors of cardiovascular- and all-cause mortality. Rats selectively bred...

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Aon MA, Cortassa S, Juhaszova M, et al. Mitochondrial health is enhanced in rats with higher vs. lower intrinsic exercise capacity and extended lifespan. NPJ Aging Mech Dis. 2021;7(1):1doi: 10.1038/s41514-020-00054-3.
Aon, M. A., Cortassa, S., Juhaszova, M., González-Reyes, J. A., Calvo-Rubio, M., Villalba, J. M., Lachance, A. D., Ziman, B. D., Mitchell, S. J., Murt, K. N., Axsom, J. E. C., Alfaras, I., Britton, S. L., Koch, L. G., de Cabo, R., Lakatta, E. G., & Sollott, S. J. (2021). Mitochondrial health is enhanced in rats with higher vs. lower intrinsic exercise capacity and extended lifespan. NPJ aging and mechanisms of disease, 7(1), 1. https://doi.org/10.1038/s41514-020-00054-3
Aon, Miguel A, et al. "Mitochondrial health is enhanced in rats with higher vs. lower intrinsic exercise capacity and extended lifespan." NPJ aging and mechanisms of disease vol. 7,1 (2021): 1. doi: https://doi.org/10.1038/s41514-020-00054-3
Aon MA, Cortassa S, Juhaszova M, González-Reyes JA, Calvo-Rubio M, Villalba JM, Lachance AD, Ziman BD, Mitchell SJ, Murt KN, Axsom JEC, Alfaras I, Britton SL, Koch LG, de Cabo R, Lakatta EG, Sollott SJ. Mitochondrial health is enhanced in rats with higher vs. lower intrinsic exercise capacity and extended lifespan. NPJ Aging Mech Dis. 2021 Jan 04;7(1):1. doi: 10.1038/s41514-020-00054-3. PMID: 33398019; PMCID: PMC7782588.
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Vessel ultrasound sonographic assessment of soluble receptor for advanced glycation end products efficacy in a rat balloon injury model.

Current therapeutic research, clinical and experimental

Tae HJ, Petrashevskaya N, Ahmet I, Park S, Talan MI, Lakatta EG, Lin L.
PMID: 25408789
Curr Ther Res Clin Exp. 2014 Nov 11;76:110-5. doi: 10.1016/j.curtheres.2014.08.001. eCollection 2014 Dec.

OBJECTIVE: We aimed to assess the therapeutic efficacy of differentially modified soluble receptor for advanced glycation end products (sRAGE) in vivo using vessel ultrasound sonography and to compare the sonography data with those from postmortem histomorphologic analyses to have...

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Tae HJ, Petrashevskaya N, Ahmet I, et al. Vessel ultrasound sonographic assessment of soluble receptor for advanced glycation end products efficacy in a rat balloon injury model. Curr Ther Res Clin Exp. 2014;76:110-5doi: 10.1016/j.curtheres.2014.08.001.
Tae, H. J., Petrashevskaya, N., Ahmet, I., Park, S., Talan, M. I., Lakatta, E. G., & Lin, L. (2014). Vessel ultrasound sonographic assessment of soluble receptor for advanced glycation end products efficacy in a rat balloon injury model. Current therapeutic research, clinical and experimental, 76110-5. https://doi.org/10.1016/j.curtheres.2014.08.001
Tae, Hyun-Jin, et al. "Vessel ultrasound sonographic assessment of soluble receptor for advanced glycation end products efficacy in a rat balloon injury model." Current therapeutic research, clinical and experimental vol. 76 (2014): 110-5. doi: https://doi.org/10.1016/j.curtheres.2014.08.001
Tae HJ, Petrashevskaya N, Ahmet I, Park S, Talan MI, Lakatta EG, Lin L. Vessel ultrasound sonographic assessment of soluble receptor for advanced glycation end products efficacy in a rat balloon injury model. Curr Ther Res Clin Exp. 2014 Nov 11;76:110-5. doi: 10.1016/j.curtheres.2014.08.001. eCollection 2014 Dec. PMID: 25408789; PMCID: PMC4229510.
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Aging Effects on the Vasculature in Health: Risk Factors for Cardiovascular Disease.

The American journal of geriatric cardiology

Lakatta E.
PMID: 11416319
Am J Geriatr Cardiol. 1994 Nov;3(6):11-17.

No abstract available.

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Lakatta E. Aging Effects on the Vasculature in Health: Risk Factors for Cardiovascular Disease. Am J Geriatr Cardiol. 1994;3(6):11-17
Lakatta, E. (1994). Aging Effects on the Vasculature in Health: Risk Factors for Cardiovascular Disease. The American journal of geriatric cardiology, 3(6), 11-17.
Lakatta, Edward. "Aging Effects on the Vasculature in Health: Risk Factors for Cardiovascular Disease." The American journal of geriatric cardiology vol. 3,6 (1994): 11-17.
Lakatta E. Aging Effects on the Vasculature in Health: Risk Factors for Cardiovascular Disease. Am J Geriatr Cardiol. 1994 Nov;3(6):11-17. PMID: 11416319.
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Cardiovascular Aging: Perspectives From Humans to Rodents.

The American journal of geriatric cardiology

Lakatta EG.
PMID: 11416479
Am J Geriatr Cardiol. 1998 Nov;7(6):32-45.

In order to define and target the specific characteristics of cardiovascular aging that render aging as a risk factor for diseases (such as atherosclerosis, hypertension, stroke, and heart failure) that reach epidemic proportions among older individuals, it is essential...

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Lakatta EG. Cardiovascular Aging: Perspectives From Humans to Rodents. Am J Geriatr Cardiol. 1998;7(6):32-45
Lakatta, E. G. (1998). Cardiovascular Aging: Perspectives From Humans to Rodents. The American journal of geriatric cardiology, 7(6), 32-45.
Lakatta, Edward G.. "Cardiovascular Aging: Perspectives From Humans to Rodents." The American journal of geriatric cardiology vol. 7,6 (1998): 32-45.
Lakatta EG. Cardiovascular Aging: Perspectives From Humans to Rodents. Am J Geriatr Cardiol. 1998 Nov;7(6):32-45. PMID: 11416479.
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Mouse RAGE Variant 4 Is a Dominant Membrane Receptor that Does Not Shed to Generate Soluble RAGE.

PloS one

Peng Y, Horwitz N, Lakatta EG, Lin L.
PMID: 27655067
PLoS One. 2016 Sep 21;11(9):e0153657. doi: 10.1371/journal.pone.0153657. eCollection 2016.

The receptor for advanced glycation end products (RAGE) is a multi-ligand, immunoglobulin-like receptor that has been implicated in aging-associated diseases. Recent studies have demonstrated that both human and murine Ager genes undergo extensive alternative splicing that generates multiple putative...

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Peng Y, Horwitz N, Lakatta EG, et al. Mouse RAGE Variant 4 Is a Dominant Membrane Receptor that Does Not Shed to Generate Soluble RAGE. PLoS One. 2016;11(9):e0153657doi: 10.1371/journal.pone.0153657.
Peng, Y., Horwitz, N., Lakatta, E. G., & Lin, L. (2016). Mouse RAGE Variant 4 Is a Dominant Membrane Receptor that Does Not Shed to Generate Soluble RAGE. PloS one, 11(9), e0153657. https://doi.org/10.1371/journal.pone.0153657
Peng, Yunqian, et al. "Mouse RAGE Variant 4 Is a Dominant Membrane Receptor that Does Not Shed to Generate Soluble RAGE." PloS one vol. 11,9 (2016): e0153657. doi: https://doi.org/10.1371/journal.pone.0153657
Peng Y, Horwitz N, Lakatta EG, Lin L. Mouse RAGE Variant 4 Is a Dominant Membrane Receptor that Does Not Shed to Generate Soluble RAGE. PLoS One. 2016 Sep 21;11(9):e0153657. doi: 10.1371/journal.pone.0153657. eCollection 2016. PMID: 27655067; PMCID: PMC5031407.
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Acute hemodynamic effects of erythropoietin do not mediate its cardioprotective properties.

Biology open

Ahmet I, Lakatta EG, Talan MI.
PMID: 23213383
Biol Open. 2012 Oct 15;1(10):1049-53. doi: 10.1242/bio.20122378. Epub 2012 Aug 22.

Activation of nitric oxide (NO) signaling is considered, at list partially, a mechanistic basis for EPO-induced cardioprotection. Surprisingly, hemodynamic response subsequent to NO activation after EPO administration has never been reported. The objectives of this study were to evaluate...

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Ahmet I, Lakatta EG, Talan MI. Acute hemodynamic effects of erythropoietin do not mediate its cardioprotective properties. Biol Open. 2012;1(10):1049-53doi: 10.1242/bio.20122378.
Ahmet, I., Lakatta, E. G., & Talan, M. I. (2012). Acute hemodynamic effects of erythropoietin do not mediate its cardioprotective properties. Biology open, 1(10), 1049-53. https://doi.org/10.1242/bio.20122378
Ahmet, Ismayil, et al. "Acute hemodynamic effects of erythropoietin do not mediate its cardioprotective properties." Biology open vol. 1,10 (2012): 1049-53. doi: https://doi.org/10.1242/bio.20122378
Ahmet I, Lakatta EG, Talan MI. Acute hemodynamic effects of erythropoietin do not mediate its cardioprotective properties. Biol Open. 2012 Oct 15;1(10):1049-53. doi: 10.1242/bio.20122378. Epub 2012 Aug 22. PMID: 23213383; PMCID: PMC3507179.
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Cardiovascular ageing in health sets the stage for cardiovascular disease.

Heart, lung & circulation

Lakatta EG.
PMID: 16352074
Heart Lung Circ. 2002;11(2):76-91. doi: 10.1046/j.1444-2892.2002.00126.x.

The incidence and prevalence of coronary disease, hypertension, heart failure and stroke increase exponentially with advancing age. While epidemiologic studies have discovered that aspects of lifestyle and genetics are risk factors for these diseases, age, per se, confers the...

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Lakatta EG. Cardiovascular ageing in health sets the stage for cardiovascular disease. Heart Lung Circ. 2002;11(2):76-91doi: 10.1046/j.1444-2892.2002.00126.x.
Lakatta, E. G. (2002). Cardiovascular ageing in health sets the stage for cardiovascular disease. Heart, lung & circulation, 11(2), 76-91. https://doi.org/10.1046/j.1444-2892.2002.00126.x
Lakatta, Edward G. "Cardiovascular ageing in health sets the stage for cardiovascular disease." Heart, lung & circulation vol. 11,2 (2002): 76-91. doi: https://doi.org/10.1046/j.1444-2892.2002.00126.x
Lakatta EG. Cardiovascular ageing in health sets the stage for cardiovascular disease. Heart Lung Circ. 2002;11(2):76-91. doi: 10.1046/j.1444-2892.2002.00126.x. PMID: 16352074.
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Reduced vasorin enhances angiotensin II signaling within the aging arterial wall.

Oncotarget

Pintus G, Giordo R, Wang Y, Zhu W, Kim SH, Zhang L, Ni L, Zhang J, Telljohann R, McGraw KR, Monticone RE, Ferris C, Liu L, Wang M, Lakatta EG.
PMID: 29930755
Oncotarget. 2018 Jun 05;9(43):27117-27132. doi: 10.18632/oncotarget.25499. eCollection 2018 Jun 05.

The glycosylated protein vasorin physically interacts with the transforming growth factor-beta1 (TGF-β1) and functionally attenuates its fibrogenic signaling in the vascular smooth muscle cells (VSMCs) of the arterial wall. Angiotensin II (Ang II) amplifies TGF-β1 activation in the VSMCs...

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Pintus G, Giordo R, Wang Y, et al. Reduced vasorin enhances angiotensin II signaling within the aging arterial wall. Oncotarget. 2018;9(43):27117-27132doi: 10.18632/oncotarget.25499.
Pintus, G., Giordo, R., Wang, Y., Zhu, W., Kim, S. H., Zhang, L., Ni, L., Zhang, J., Telljohann, R., McGraw, K. R., Monticone, R. E., Ferris, C., Liu, L., Wang, M., & Lakatta, E. G. (2018). Reduced vasorin enhances angiotensin II signaling within the aging arterial wall. Oncotarget, 9(43), 27117-27132. https://doi.org/10.18632/oncotarget.25499
Pintus, Gianfranco, et al. "Reduced vasorin enhances angiotensin II signaling within the aging arterial wall." Oncotarget vol. 9,43 (2018): 27117-27132. doi: https://doi.org/10.18632/oncotarget.25499
Pintus G, Giordo R, Wang Y, Zhu W, Kim SH, Zhang L, Ni L, Zhang J, Telljohann R, McGraw KR, Monticone RE, Ferris C, Liu L, Wang M, Lakatta EG. Reduced vasorin enhances angiotensin II signaling within the aging arterial wall. Oncotarget. 2018 Jun 05;9(43):27117-27132. doi: 10.18632/oncotarget.25499. eCollection 2018 Jun 05. PMID: 29930755; PMCID: PMC6007470.
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