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Showing 1 to 12 of 171 entries
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What Value Can Qualitative Research Add to Quantitative Research Design? An Example From an Adolescent Idiopathic Scoliosis Trial Feasibility Study.

Qualitative health research

Toye F, Williamson E, Williams MA, Fairbank J, Lamb SE.
PMID: 27509903
Qual Health Res. 2016 Nov;26(13):1838-1850. doi: 10.1177/1049732316662446. Epub 2016 Aug 20.

Using an example of qualitative research embedded in a non-surgical feasibility trial, we explore the benefits of including qualitative research in trial design and reflect on epistemological challenges. We interviewed 18 trial participants and used methods of Interpretive Phenomenological...

Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology.

Frontiers in molecular neuroscience

Maphis NM, Jiang S, Binder J, Wright C, Gopalan B, Lamb BT, Bhaskar K.
PMID: 28367114
Front Mol Neurosci. 2017 Mar 17;10:69. doi: 10.3389/fnmol.2017.00069. eCollection 2017.

Increasing evidence suggests that hyperphosphorylation and aggregation of microtubule-associated protein tau (MAPT or tau) correlates with the development of cognitive impairment in Alzheimer's disease (AD) and related tauopathies. While numerous attempts have been made to model AD-relevant tau pathology...

Performance of chromosomal microarray for patients with intellectual disabilities/developmental delay, autism, and multiple congenital anomalies in a Chinese cohort.

Molecular cytogenetics

Chong WW, Lo IF, Lam ST, Wang CC, Luk HM, Leung TY, Choy KW.
PMID: 24926319
Mol Cytogenet. 2014 May 23;7:34. doi: 10.1186/1755-8166-7-34. eCollection 2014.

BACKGROUND: Chromosomal microarray (CMA) is currently the first-tier genetic test for patients with idiopathic neuropsychiatric diseases in many countries. Its improved diagnostic yield over karyotyping and other molecular testing facilitates the identification of the underlying causes of neuropsychiatric diseases....

The problem may be more difficult to solve than it appears: a reply to zelaznik.

Journal of motor behavior

Klapp ST.
PMID: 15178527
J Mot Behav. 1978 Mar;10(1):81-2. doi: 10.1080/00222895.1978.10735139.

Zelznik (1978) and I agree that his comment applies only to Experiment 1 of my series of three experiments, and I note that the weight of my argument was based on the other two experiments. Although agreeing with his...

Can people tap concurrent bimanual rhythms independently?.

Journal of motor behavior

Klapp ST, Nelson JM, Jagacinski RJ.
PMID: 20037035
J Mot Behav. 1998 Dec;30(4):301-22. doi: 10.1080/00222899809601346.

If people could tap 2 rhythms independently, 1 rhythm with each hand, training people to tap the rhythms separately should enable them to tap the rhythms concurrently. However, nonmusician participants in the present experiments were unable to produce accurate...

Peripheral nerve stimulation inhibits nociceptive processing: an electrophysiological study in healthy volunteers.

Neuromodulation : journal of the International Neuromodulation Society

Ellrich J, Lamp S.
PMID: 22151549
Neuromodulation. 2005 Oct;8(4):225-32. doi: 10.1111/j.1525-1403.2005.00029.x.

Objectives.  Electric peripheral nerve stimulation (PNS) is a neuromodulatory therapy in pain patients. The efficacy of this neurosurgical pain treatment is controversial because its antinociceptive effect in humans has not been objectively proven so far. Materials and Methods.  Noxious...

Reduction of ventilator-associated pneumonia in the Neuroscience Intensive Care Unit: a multimodality prevention and testing protocol.

Journal of neurosurgical sciences

Johnson M, Rocque B, Kamps T, Medow J.
PMID: 24091431
J Neurosurg Sci. 2013 Dec;57(4):293-6.

AIM: Ventilator-associated pneumonia (VAP) is a serious concern for patients in the Neuroscience Intensive Care Unit (NSICU). The risks to patients are significant and the monetary costs are astronomical. We review a multimodality approach that substantially reduced VAP rate...

Multidisciplinary service utilization pattern by advanced head and neck cancer patients: a single institution study.

International journal of otolaryngology

Junn JC, Kim IA, Zahurak ML, Tan M, Fan KY, Lake ST, Zaboli D, Messing BP, Ulmer K, Harrer KB, Gold D, Ryniak KL, Zinreich ES, Tang M, Levine MA, Blanco RG, Saunders JR, Califano JA, Ha PK.
PMID: 23118755
Int J Otolaryngol. 2012;2012:628578. doi: 10.1155/2012/628578. Epub 2012 Oct 18.

Purpose. To analyze the patterns and associations of adjunctive service visits by head and neck cancer patients receiving primary, concurrent chemoradiation therapy. Methods. Retrospective chart review of patients receiving adjunctive support during a uniform chemoradiation regimen for stages III-IV...

Batch- and continuous-culture studies of a methane-utilizing mixed culture.

Biotechnology and bioengineering

Lamb SC, Garver JC.
PMID: 29345765
Biotechnol Bioeng. 1980 Oct;22(10):2097-2118. doi: 10.1002/bit.260221009.

A methane-utilizing mixed culture isolated from activated sludge by selective enrichment at 45°C was found to consist of three interacting species: a methaneutilizing bacterium, a citrate-utilizing bacterium, and a methanol-utilizing bacterium. All three species grew well at 45°C. Three...

Prevention of Falls Network Europe: a thematic network aimed at introducing good practice in effective falls prevention across Europe.

European journal of ageing

Skelton DA, Becker C, Lamb SE, Close JCT, Zijlstra W, Yardley L, Todd CJ.
PMID: 28794706
Eur J Ageing. 2004 Dec;1(1):89-94. doi: 10.1007/s10433-004-0008-z. Epub 2004 Nov 04.

The Prevention of Falls Network Europe (ProFaNE) aims to improve quality of life of the ageing population by focussing on a major cause of disability and distress: falls. The thematic network is funded by the European Commission and brings...

Supposed Case of Ergotism.

The British and foreign medico-chirurgical review

Camps T.
PMID: 30163810
Br Foreign Med Chir Rev. 1855 Jul;16(31):196-205.

No abstract available.

Endotoxin- and mechanical stress-induced epigenetic changes in the regulation of the nicotinamide phosphoribosyltransferase promoter.

Pulmonary circulation

Elangovan VR, Camp SM, Kelly GT, Desai AA, Adyshev D, Sun X, Black SM, Wang T, Garcia JG.
PMID: 28090296
Pulm Circ. 2016 Dec;6(4):539-544. doi: 10.1086/688761.

Mechanical ventilation, a lifesaving intervention for patients with acute respiratory distress syndrome (ARDS), also unfortunately contributes to excessive mechanical stress and impaired lung physiological and structural integrity. We have elsewhere established the pivotal role of increased nicotinamide phosphoribosyltransferase (NAMPT)...

Showing 1 to 12 of 171 entries