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Showing 1 to 12 of 18 entries
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Cerebral Blood Flow and Metabolism after Intracranial Trauma.

Progress in neurological surgery

Langfitt TW, Obrist WD.
PMID: 27242047
Prog Neurol Surg. 1981;10:14-48. doi: 10.1159/000384767. Epub 2015 Apr 02.

No abstract available.

Cite
Langfitt TW, Obrist WD. Cerebral Blood Flow and Metabolism after Intracranial Trauma. Prog Neurol Surg. 2015;10:14-48doi: 10.1159/000384767.
Langfitt, T. W., & Obrist, W. D. (1981). Cerebral Blood Flow and Metabolism after Intracranial Trauma. Progress in neurological surgery, 1014-48. https://doi.org/10.1159/000384767
Langfitt, T W, and Obrist, W D. "Cerebral Blood Flow and Metabolism after Intracranial Trauma." Progress in neurological surgery vol. 10 (1981): 14-48. doi: https://doi.org/10.1159/000384767
Langfitt TW, Obrist WD. Cerebral Blood Flow and Metabolism after Intracranial Trauma. Prog Neurol Surg. 1981;10:14-48. doi: 10.1159/000384767. Epub 2015 Apr 02. PMID: 27242047.
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A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function.

Cancer discovery

Lange S, Sand LGL, Bell M, Patil SL, Langfitt D, Gottschalk S.
PMID: 33563660
Cancer Discov. 2021 Jul;11(7):1661-1671. doi: 10.1158/2159-8290.CD-20-0896. Epub 2021 Feb 09.

The inability of chimeric antigen receptor (CAR) T cells to sustain their effector function after repeated exposure to tumor cells is a major obstacle to their success in patients with solid tumors. To overcome this limitation, we designed a...

Cite
Lange S, Sand LGL, Bell M, et al. A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function. Cancer Discov. 2021;11(7):1661-1671doi: 10.1158/2159-8290.CD-20-0896.
Lange, S., Sand, L. G. L., Bell, M., Patil, S. L., Langfitt, D., & Gottschalk, S. (2021). A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function. Cancer discovery, 11(7), 1661-1671. https://doi.org/10.1158/2159-8290.CD-20-0896
Lange, Shannon, et al. "A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function." Cancer discovery vol. 11,7 (2021): 1661-1671. doi: https://doi.org/10.1158/2159-8290.CD-20-0896
Lange S, Sand LGL, Bell M, Patil SL, Langfitt D, Gottschalk S. A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function. Cancer Discov. 2021 Jul;11(7):1661-1671. doi: 10.1158/2159-8290.CD-20-0896. Epub 2021 Feb 09. PMID: 33563660; PMCID: PMC8292158.
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Utility of Radiographs, Computed Tomography, and Three Dimensional Computed Tomography Pelvis Reconstruction for Identification of Acetabular Defects in Residency Training.

Hip & pelvis

Plate JF, Shields JS, Langfitt MK, Bolognesi MP, Lang JE, Seyler TM.
PMID: 29250499
Hip Pelvis. 2017 Dec;29(4):247-252. doi: 10.5371/hp.2017.29.4.247. Epub 2017 Dec 01.

PURPOSE: The Paprosky classification system of acetabular defects is complex and its reliability has been questioned. The purpose of this study was to evaluate the effectiveness of different radiologic imaging modalities in classifying acetabular defects in revision total hip...

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Plate JF, Shields JS, Langfitt MK, et al. Utility of Radiographs, Computed Tomography, and Three Dimensional Computed Tomography Pelvis Reconstruction for Identification of Acetabular Defects in Residency Training. Hip Pelvis. 2017;29(4):247-252doi: 10.5371/hp.2017.29.4.247.
Plate, J. F., Shields, J. S., Langfitt, M. K., Bolognesi, M. P., Lang, J. E., & Seyler, T. M. (2017). Utility of Radiographs, Computed Tomography, and Three Dimensional Computed Tomography Pelvis Reconstruction for Identification of Acetabular Defects in Residency Training. Hip & pelvis, 29(4), 247-252. https://doi.org/10.5371/hp.2017.29.4.247
Plate, Johannes F, et al. "Utility of Radiographs, Computed Tomography, and Three Dimensional Computed Tomography Pelvis Reconstruction for Identification of Acetabular Defects in Residency Training." Hip & pelvis vol. 29,4 (2017): 247-252. doi: https://doi.org/10.5371/hp.2017.29.4.247
Plate JF, Shields JS, Langfitt MK, Bolognesi MP, Lang JE, Seyler TM. Utility of Radiographs, Computed Tomography, and Three Dimensional Computed Tomography Pelvis Reconstruction for Identification of Acetabular Defects in Residency Training. Hip Pelvis. 2017 Dec;29(4):247-252. doi: 10.5371/hp.2017.29.4.247. Epub 2017 Dec 01. PMID: 29250499; PMCID: PMC5729167.
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A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function.

Cancer discovery

Lange S, Sand LGL, Bell M, Patil SL, Langfitt D, Gottschalk S.
PMID: 33563660
Cancer Discov. 2021 Jul;11(7):1661-1671. doi: 10.1158/2159-8290.CD-20-0896. Epub 2021 Feb 09.

The inability of chimeric antigen receptor (CAR) T cells to sustain their effector function after repeated exposure to tumor cells is a major obstacle to their success in patients with solid tumors. To overcome this limitation, we designed a...

Cite
Lange S, Sand LGL, Bell M, et al. A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function. Cancer Discov. 2021;11(7):1661-1671doi: 10.1158/2159-8290.CD-20-0896.
Lange, S., Sand, L. G. L., Bell, M., Patil, S. L., Langfitt, D., & Gottschalk, S. (2021). A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function. Cancer discovery, 11(7), 1661-1671. https://doi.org/10.1158/2159-8290.CD-20-0896
Lange, Shannon, et al. "A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function." Cancer discovery vol. 11,7 (2021): 1661-1671. doi: https://doi.org/10.1158/2159-8290.CD-20-0896
Lange S, Sand LGL, Bell M, Patil SL, Langfitt D, Gottschalk S. A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function. Cancer Discov. 2021 Jul;11(7):1661-1671. doi: 10.1158/2159-8290.CD-20-0896. Epub 2021 Feb 09. PMID: 33563660; PMCID: PMC8292158.
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Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity.

Science translational medicine

Prinzing B, Zebley CC, Petersen CT, Fan Y, Anido AA, Yi Z, Nguyen P, Houke H, Bell M, Haydar D, Brown C, Boi SK, Alli S, Crawford JC, Riberdy JM, Park JJ, Zhou S, Velasquez MP, DeRenzo C, Lazzarotto CR, Tsai SQ, Vogel P, Pruett-Miller SM, Langfitt DM, Gottschalk S, Youngblood B, Krenciute G.
PMID: 34788079
Sci Transl Med. 2021 Nov 17;13(620):eabh0272. doi: 10.1126/scitranslmed.abh0272. Epub 2021 Nov 17.

[Figure: see text].

Cite
Prinzing B, Zebley CC, Petersen CT, et al. Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity. Sci Transl Med. 2021;13(620):eabh0272doi: 10.1126/scitranslmed.abh0272.
Prinzing, B., Zebley, C. C., Petersen, C. T., Fan, Y., Anido, A. A., Yi, Z., Nguyen, P., Houke, H., Bell, M., Haydar, D., Brown, C., Boi, S. K., Alli, S., Crawford, J. C., Riberdy, J. M., Park, J. J., Zhou, S., Velasquez, M. P., DeRenzo, C., Lazzarotto, C. R., Tsai, S. Q., Vogel, P., Pruett-Miller, S. M., Langfitt, D. M., Gottschalk, S., Youngblood, B., & Krenciute, G. (2021). Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity. Science translational medicine, 13(620), eabh0272. https://doi.org/10.1126/scitranslmed.abh0272
Prinzing, Brooke, et al. "Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity." Science translational medicine vol. 13,620 (2021): eabh0272. doi: https://doi.org/10.1126/scitranslmed.abh0272
Prinzing B, Zebley CC, Petersen CT, Fan Y, Anido AA, Yi Z, Nguyen P, Houke H, Bell M, Haydar D, Brown C, Boi SK, Alli S, Crawford JC, Riberdy JM, Park JJ, Zhou S, Velasquez MP, DeRenzo C, Lazzarotto CR, Tsai SQ, Vogel P, Pruett-Miller SM, Langfitt DM, Gottschalk S, Youngblood B, Krenciute G. Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity. Sci Transl Med. 2021 Nov 17;13(620):eabh0272. doi: 10.1126/scitranslmed.abh0272. Epub 2021 Nov 17. PMID: 34788079.
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CD19-CAR T cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia.

Cell reports

Zebley CC, Brown C, Mi T, Fan Y, Alli S, Boi S, Galletti G, Lugli E, Langfitt D, Metais JY, Lockey T, Meagher M, Triplett B, Talleur AC, Gottschalk S, Youngblood B.
PMID: 34852226
Cell Rep. 2021 Nov 30;37(9):110079. doi: 10.1016/j.celrep.2021.110079.

CD19-CAR T cell therapy has evolved into the standard of care for relapsed/refractory B cell acute lymphoblastic leukemia (ALL); however, limited persistence of the CAR T cells enables tumor relapse for many patients. To gain a deeper understanding of...

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Zebley CC, Brown C, Mi T, et al. CD19-CAR T cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia. Cell Rep. 2021;37(9):110079doi: 10.1016/j.celrep.2021.110079.
Zebley, C. C., Brown, C., Mi, T., Fan, Y., Alli, S., Boi, S., Galletti, G., Lugli, E., Langfitt, D., Metais, J. Y., Lockey, T., Meagher, M., Triplett, B., Talleur, A. C., Gottschalk, S., & Youngblood, B. (2021). CD19-CAR T cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia. Cell reports, 37(9), 110079. https://doi.org/10.1016/j.celrep.2021.110079
Zebley, Caitlin C, et al. "CD19-CAR T cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia." Cell reports vol. 37,9 (2021): 110079. doi: https://doi.org/10.1016/j.celrep.2021.110079
Zebley CC, Brown C, Mi T, Fan Y, Alli S, Boi S, Galletti G, Lugli E, Langfitt D, Metais JY, Lockey T, Meagher M, Triplett B, Talleur AC, Gottschalk S, Youngblood B. CD19-CAR T cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia. Cell Rep. 2021 Nov 30;37(9):110079. doi: 10.1016/j.celrep.2021.110079. PMID: 34852226.
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A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function.

Cancer discovery

Lange S, Sand LGL, Bell M, Patil SL, Langfitt D, Gottschalk S.
PMID: 33563660
Cancer Discov. 2021 Jul;11(7):1661-1671. doi: 10.1158/2159-8290.CD-20-0896. Epub 2021 Feb 09.

The inability of chimeric antigen receptor (CAR) T cells to sustain their effector function after repeated exposure to tumor cells is a major obstacle to their success in patients with solid tumors. To overcome this limitation, we designed a...

Cite
Lange S, Sand LGL, Bell M, et al. A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function. Cancer Discov. 2021;11(7):1661-1671doi: 10.1158/2159-8290.CD-20-0896.
Lange, S., Sand, L. G. L., Bell, M., Patil, S. L., Langfitt, D., & Gottschalk, S. (2021). A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function. Cancer discovery, 11(7), 1661-1671. https://doi.org/10.1158/2159-8290.CD-20-0896
Lange, Shannon, et al. "A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function." Cancer discovery vol. 11,7 (2021): 1661-1671. doi: https://doi.org/10.1158/2159-8290.CD-20-0896
Lange S, Sand LGL, Bell M, Patil SL, Langfitt D, Gottschalk S. A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function. Cancer Discov. 2021 Jul;11(7):1661-1671. doi: 10.1158/2159-8290.CD-20-0896. Epub 2021 Feb 09. PMID: 33563660; PMCID: PMC8292158.
Copy Download .nbib Format: NLM
Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity.

Science translational medicine

Prinzing B, Zebley CC, Petersen CT, Fan Y, Anido AA, Yi Z, Nguyen P, Houke H, Bell M, Haydar D, Brown C, Boi SK, Alli S, Crawford JC, Riberdy JM, Park JJ, Zhou S, Velasquez MP, DeRenzo C, Lazzarotto CR, Tsai SQ, Vogel P, Pruett-Miller SM, Langfitt DM, Gottschalk S, Youngblood B, Krenciute G.
PMID: 34788079
Sci Transl Med. 2021 Nov 17;13(620):eabh0272. doi: 10.1126/scitranslmed.abh0272. Epub 2021 Nov 17.

[Figure: see text].

Cite
Prinzing B, Zebley CC, Petersen CT, et al. Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity. Sci Transl Med. 2021;13(620):eabh0272doi: 10.1126/scitranslmed.abh0272.
Prinzing, B., Zebley, C. C., Petersen, C. T., Fan, Y., Anido, A. A., Yi, Z., Nguyen, P., Houke, H., Bell, M., Haydar, D., Brown, C., Boi, S. K., Alli, S., Crawford, J. C., Riberdy, J. M., Park, J. J., Zhou, S., Velasquez, M. P., DeRenzo, C., Lazzarotto, C. R., Tsai, S. Q., Vogel, P., Pruett-Miller, S. M., Langfitt, D. M., Gottschalk, S., Youngblood, B., & Krenciute, G. (2021). Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity. Science translational medicine, 13(620), eabh0272. https://doi.org/10.1126/scitranslmed.abh0272
Prinzing, Brooke, et al. "Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity." Science translational medicine vol. 13,620 (2021): eabh0272. doi: https://doi.org/10.1126/scitranslmed.abh0272
Prinzing B, Zebley CC, Petersen CT, Fan Y, Anido AA, Yi Z, Nguyen P, Houke H, Bell M, Haydar D, Brown C, Boi SK, Alli S, Crawford JC, Riberdy JM, Park JJ, Zhou S, Velasquez MP, DeRenzo C, Lazzarotto CR, Tsai SQ, Vogel P, Pruett-Miller SM, Langfitt DM, Gottschalk S, Youngblood B, Krenciute G. Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity. Sci Transl Med. 2021 Nov 17;13(620):eabh0272. doi: 10.1126/scitranslmed.abh0272. Epub 2021 Nov 17. PMID: 34788079; PMCID: PMC8733956.
Copy Download .nbib Format: NLM
Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity.

Science translational medicine

Prinzing B, Zebley CC, Petersen CT, Fan Y, Anido AA, Yi Z, Nguyen P, Houke H, Bell M, Haydar D, Brown C, Boi SK, Alli S, Crawford JC, Riberdy JM, Park JJ, Zhou S, Velasquez MP, DeRenzo C, Lazzarotto CR, Tsai SQ, Vogel P, Pruett-Miller SM, Langfitt DM, Gottschalk S, Youngblood B, Krenciute G.
PMID: 34788079
Sci Transl Med. 2021 Nov 17;13(620):eabh0272. doi: 10.1126/scitranslmed.abh0272. Epub 2021 Nov 17.

[Figure: see text].

Cite
Prinzing B, Zebley CC, Petersen CT, et al. Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity. Sci Transl Med. 2021;13(620):eabh0272doi: 10.1126/scitranslmed.abh0272.
Prinzing, B., Zebley, C. C., Petersen, C. T., Fan, Y., Anido, A. A., Yi, Z., Nguyen, P., Houke, H., Bell, M., Haydar, D., Brown, C., Boi, S. K., Alli, S., Crawford, J. C., Riberdy, J. M., Park, J. J., Zhou, S., Velasquez, M. P., DeRenzo, C., Lazzarotto, C. R., Tsai, S. Q., Vogel, P., Pruett-Miller, S. M., Langfitt, D. M., Gottschalk, S., Youngblood, B., & Krenciute, G. (2021). Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity. Science translational medicine, 13(620), eabh0272. https://doi.org/10.1126/scitranslmed.abh0272
Prinzing, Brooke, et al. "Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity." Science translational medicine vol. 13,620 (2021): eabh0272. doi: https://doi.org/10.1126/scitranslmed.abh0272
Prinzing B, Zebley CC, Petersen CT, Fan Y, Anido AA, Yi Z, Nguyen P, Houke H, Bell M, Haydar D, Brown C, Boi SK, Alli S, Crawford JC, Riberdy JM, Park JJ, Zhou S, Velasquez MP, DeRenzo C, Lazzarotto CR, Tsai SQ, Vogel P, Pruett-Miller SM, Langfitt DM, Gottschalk S, Youngblood B, Krenciute G. Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity. Sci Transl Med. 2021 Nov 17;13(620):eabh0272. doi: 10.1126/scitranslmed.abh0272. Epub 2021 Nov 17. PMID: 34788079; PMCID: PMC8733956.
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Annual report of the Section on Medical Ethics.

Transactions & studies of the College of Physicians of Philadelphia

Langfitt T.
PMID: 10741203
Trans Stud Coll Physicians Phila. 1999 Dec;21:13-4.

No abstract available.

Cite
Langfitt T. Annual report of the Section on Medical Ethics. Trans Stud Coll Physicians Phila. 1999;21:13-4
Langfitt, T. (1999). Annual report of the Section on Medical Ethics. Transactions & studies of the College of Physicians of Philadelphia, 2113-4.
Langfitt. "Annual report of the Section on Medical Ethics." Transactions & studies of the College of Physicians of Philadelphia vol. 21 (1999): 13-4.
Langfitt T. Annual report of the Section on Medical Ethics. Trans Stud Coll Physicians Phila. 1999 Dec;21:13-4. PMID: 10741203.
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Measuring neurodevelopment in low-resource settings.

The Lancet. Child & adolescent health

Gladstone M, Abubakar A, Idro R, Langfitt J, Newton CR.
PMID: 30169180
Lancet Child Adolesc Health. 2017 Dec;1(4):258-259. doi: 10.1016/S2352-4642(17)30117-7. Epub 2017 Oct 09.

No abstract available.

Cite
Gladstone M, Abubakar A, Idro R, et al. Measuring neurodevelopment in low-resource settings. Lancet Child Adolesc Health. 2017;1(4):258-259doi: 10.1016/S2352-4642(17)30117-7.
Gladstone, M., Abubakar, A., Idro, R., Langfitt, J., & Newton, C. R. (2017). Measuring neurodevelopment in low-resource settings. The Lancet. Child & adolescent health, 1(4), 258-259. https://doi.org/10.1016/S2352-4642(17)30117-7
Gladstone, Melissa, et al. "Measuring neurodevelopment in low-resource settings." The Lancet. Child & adolescent health vol. 1,4 (2017): 258-259. doi: https://doi.org/10.1016/S2352-4642(17)30117-7
Gladstone M, Abubakar A, Idro R, Langfitt J, Newton CR. Measuring neurodevelopment in low-resource settings. Lancet Child Adolesc Health. 2017 Dec;1(4):258-259. doi: 10.1016/S2352-4642(17)30117-7. Epub 2017 Oct 09. PMID: 30169180.
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Bundled payments in total joint arthroplasty and spine surgery.

Current reviews in musculoskeletal medicine

Sullivan R, Jarvis LD, O'Gara T, Langfitt M, Emory C.
PMID: 28364146
Curr Rev Musculoskelet Med. 2017 Jun;10(2):218-223. doi: 10.1007/s12178-017-9405-8.

PURPOSE OF REVIEW: The goal of this manuscript is to provide an overview and analysis of bundled payment models for joint replacement and select spine procedures. Advantages and disadvantages of bundled payment models will be discussed.RECENT FINDINGS: In select...

Cite
Sullivan R, Jarvis LD, O'Gara T, et al. Bundled payments in total joint arthroplasty and spine surgery. Curr Rev Musculoskelet Med. 2017;10(2):218-223doi: 10.1007/s12178-017-9405-8.
Sullivan, R., Jarvis, L. D., O'Gara, T., Langfitt, M., & Emory, C. (2017). Bundled payments in total joint arthroplasty and spine surgery. Current reviews in musculoskeletal medicine, 10(2), 218-223. https://doi.org/10.1007/s12178-017-9405-8
Sullivan, Rashad, et al. "Bundled payments in total joint arthroplasty and spine surgery." Current reviews in musculoskeletal medicine vol. 10,2 (2017): 218-223. doi: https://doi.org/10.1007/s12178-017-9405-8
Sullivan R, Jarvis LD, O'Gara T, Langfitt M, Emory C. Bundled payments in total joint arthroplasty and spine surgery. Curr Rev Musculoskelet Med. 2017 Jun;10(2):218-223. doi: 10.1007/s12178-017-9405-8. PMID: 28364146; PMCID: PMC5435636.
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Showing 1 to 12 of 18 entries