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Showing 1 to 12 of 829 entries
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How to inform: comparing written and video education interventions to increase human papillomavirus knowledge and vaccination intentions in young adults

education interventions

Lau E, Perez S.
GSID: He1Unp7Y_KYJ
A Krawczyk, E Lau, S Perez, V Delisle… - Journal of American …, 2012 - Taylor & Francis

… The present study is the first randomized-control design study comparing the efficacy of written and video HPV interventions that are guided by a theoretical framework. Both the written and video interventions facilitate consistent delivery of HPV education and...

Ready for consideration: International organizational development and change as an emerging field of practice

Science interventions

Lau CM.
GSID: FsLwnNfK8vYJ
JE Neumann, CM Lau… - The Journal of Applied …, 2009 - journals.sagepub.com

International organization1 development and change (OD&C) can be understood as an emerging field of applied behavioral and social science and of practice-based research …

Palladium-Catalyzed Arylation of Carbasugars Enables the Discovery of Potent and Selective SGLT2 Inhibitors.

Angewandte Chemie (International ed. in English)

Ng WL, Lau KM, Lau CB, Shing TK.
PMID: 27699962
Angew Chem Int Ed Engl. 2016 Oct 24;55(44):13818-13821. doi: 10.1002/anie.201608758. Epub 2016 Oct 04.

Selective inhibition of the transporter protein sodium-glucose cotransporter 2 (SGLT2) has emerged as a promising way to control blood glucose level in diabetes patients. Reported herein is a short and convergent synthetic route towards some small-molecule SGLT2 inhibitors by...

Hypercrosslinked Additives for Ageless Gas-Separation Membranes.

Angewandte Chemie (International ed. in English)

Lau CH, Mulet X, Konstas K, Doherty CM, Sani MA, Separovic F, Hill MR, Wood CD.
PMID: 26749173
Angew Chem Int Ed Engl. 2016 Feb 05;55(6):1998-2001. doi: 10.1002/anie.201508070. Epub 2016 Jan 08.

The loss of internal pores, a process known as physical aging, inhibits the long-term use of the most promising gas-separation polymers. Previously we reported that a porous aromatic framework (PAF-1) could form a remarkable nanocomposite with gas-separation polymers to...

Quality standards for DNA sequence variation databases to improve clinical management under development in Australia.

Applied & translational genomics

Bennetts B, Caramins M, Hsu A, Lau C, Mead S, Meldrum C, Smith TD, Suthers G, Taylor GR, Cotton RG, Tyrrell V.
PMID: 27294016
Appl Transl Genom. 2014 Jul 10;3(3):54-7. doi: 10.1016/j.atg.2014.07.002. eCollection 2014 Sep 01.

Despite the routine nature of comparing sequence variations identified during clinical testing to database records, few databases meet quality requirements for clinical diagnostics. To address this issue, The Royal College of Pathologists of Australasia (RCPA) in collaboration with the...

Survival outcomes in severe congenital versus non-congenital pulmonary hypertension.

Heart Asia

Arnott C, Boehm C, Lau E, Celermajer DS.
PMID: 27326222
Heart Asia. 2016 Jan 19;8(1):3-7. doi: 10.1136/heartasia-2015-010702. eCollection 2016.

OBJECTIVE: Since 2006, our institution has cared for 70 patients with pulmonary arterial hypertension (PAH) and severe right ventricular (RV) hypertension; 44 with congenital heart disease (CHD) had Eisenmenger syndrome (ES) and 26 had PAH without CHD. We sought...

Redirecting Innovation in U.S. Health Care: Options to Decrease Spending and Increase Value.

Rand health quarterly

Garber S, Gates SM, Keeler EB, Vaiana ME, Mulcahy AW, Lau C, Kellermann AL.
PMID: 28083317
Rand Health Q. 2014 Mar 01;4(1):3. eCollection 2014.

New medical technologies are a leading driver of U.S. health care spending. This article identifies promising policy options to change which medical technologies are created, with two related policy goals: (1) Reduce total health care spending with the smallest...

Informed Consent of the Chronic Total Occlusion Patient.

Interventional cardiology clinics

Lau E, Whitlow P.
PMID: 28582022
Interv Cardiol Clin. 2012 Jul;1(3):365-372. doi: 10.1016/j.iccl.2012.04.005. Epub 2012 Jun 06.

This article focuses on the general principles of informed consent, then highlights the particular risks associated with chronic total occlusion interventions. The goal is to provide a basic framework for the interventional cardiologist to use when having consent discussions...

Getting the most out of RNA-seq data analysis.

PeerJ

Khang TF, Lau CY.
PMID: 26539333
PeerJ. 2015 Oct 29;3:e1360. doi: 10.7717/peerj.1360. eCollection 2015.

Background. A common research goal in transcriptome projects is to find genes that are differentially expressed in different phenotype classes. Biologists might wish to validate such gene candidates experimentally, or use them for downstream systems biology analysis. Producing a...

Antifungal mode of action of macrocarpal C extracted from Eucalyptus globulus Labill (Lan An) towards the dermatophyte Trichophyton mentagrophytes.

Chinese medicine

Wong JH, Lau KM, Wu YO, Cheng L, Wong CW, Yew DT, Leung PC, Fung KP, Hui M, Ng TB, Lau CB.
PMID: 26594235
Chin Med. 2015 Nov 21;10:34. doi: 10.1186/s13020-015-0068-3. eCollection 2015.

BACKGROUND: The fresh leaves of Eucalyptus globulus Labill. (Lan An) have been used in Chinese medicine for many years to treat dermatomycosis. Macrocarpal C was isolated from this herb and identified as its major antifungal component by bioassay-guided purification....

Genetic rearrangements of variable di-residue (RVD)-containing repeat arrays in a baculoviral TALEN system.

Molecular therapy. Methods & clinical development

Lau CH, Zhu H, Tay JC, Li Z, Tay FC, Chen C, Tan WK, Du S, Sia VK, Phang RZ, Tang SY, Yang C, Chi Z, Liang CC, Ning E, Wang S.
PMID: 26015987
Mol Ther Methods Clin Dev. 2014 Oct 29;1:14050. doi: 10.1038/mtm.2014.50. eCollection 2014.

Virus-derived gene transfer vectors have been successfully employed to express the transcription activator-like effector nucleases (TALENs) in mammalian cells. Since the DNA-binding domains of TALENs consist of the variable di-residue (RVD)-containing tandem repeat modules and virus genome with repeated...

Metabolomic profiling of Burkholderia pseudomallei using UHPLC-ESI-Q-TOF-MS reveals specific biomarkers including 4-methyl-5-thiazoleethanol and unique thiamine degradation pathway.

Cell & bioscience

Lau SK, Lam CW, Curreem SO, Lee KC, Chow WN, Lau CC, Sridhar S, Wong SC, Martelli P, Hui SW, Yuen KY, Woo PC.
PMID: 26097677
Cell Biosci. 2015 Jun 02;5:26. doi: 10.1186/s13578-015-0018-x. eCollection 2015.

BACKGROUND: Burkholderia pseudomallei is an emerging pathogen that causes melioidosis, a serious and potentially fatal disease which requires prolonged antibiotics to prevent relapse. However, diagnosis of melioidosis can be difficult, especially in culture-negative cases. While metabolomics represents an uprising...

Showing 1 to 12 of 829 entries