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Showing 1 to 12 of 14 entries
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Positioning genomics in biology education: content mapping of undergraduate biology textbooks.

Journal of microbiology & biology education

Wernick NL, Ndung'u E, Haughton D, Ledley FD.
PMID: 25574293
J Microbiol Biol Educ. 2014 Dec 15;15(2):268-76. doi: 10.1128/jmbe.v15i2.724. eCollection 2014 Dec.

Biological thought increasingly recognizes the centrality of the genome in constituting and regulating processes ranging from cellular systems to ecology and evolution. In this paper, we ask whether genomics is similarly positioned as a core concept in the instructional...

Pharmacokinetic considerations in somatic gene therapy.

Advanced drug delivery reviews

Shapiro Ledley T, Ledley FD.
PMID: 10837607
Adv Drug Deliv Rev. 1998 Mar 02;30(1):133-150. doi: 10.1016/s0169-409x(97)00112-9.

It is anticipated that gene therapies will be useful for achieving long durations of action with little temporal fluctuation in the level of the therapeutic gene product, localized effects in specific tissues or cell types, and levels of biological...

Wound trauma alters ionizing radiation dose assessment.

Cell & bioscience

Kiang JG, Garrison BR, Burns TM, Zhai M, Dews IC, Ney PH, Cary LH, Fukumoto R, Elliott TB, Ledney GD.
PMID: 22686656
Cell Biosci. 2012 Jun 11;2(1):20. doi: 10.1186/2045-3701-2-20.

BACKGROUND: Wounding following whole-body γ-irradiation (radiation combined injury, RCI) increases mortality. Wounding-induced increases in radiation mortality are triggered by sustained activation of inducible nitric oxide synthase pathways, persistent alteration of cytokine homeostasis, and increased susceptibility to bacterial infection. Among...

As Technologies for Nucleotide Therapeutics Mature, Products Emerge.

Molecular therapy. Nucleic acids

Beierlein JM, McNamee LM, Ledley FD.
PMID: 29246316
Mol Ther Nucleic Acids. 2017 Dec 15;9:379-386. doi: 10.1016/j.omtn.2017.10.017. Epub 2017 Oct 28.

The long path from initial research on oligonucleotide therapies to approval of antisense products is not unfamiliar. This lag resembles those encountered with monoclonal antibodies, gene therapies, and many biological targets and is consistent with studies of innovation showing...

Coronary Angioplasty of an Anomalous Coronary Artery in the Elderly: Case Report and Review of the Literature.

The American journal of geriatric cardiology

Ledley GS, Robinson KG, Kotler MN.
PMID: 11416326
Am J Geriatr Cardiol. 1995 Jan;4(1):28-30.

Newer developments in biotechnology and increasing operator experience have broadened the clinical applicability of percutaneous transluminal coronary angioplasty. These advances have allowed the treatment of patients with variant and anomalous coronary arteries and the treatment of an increasingly elderly...

Recognition of allergic conjunctivitis in patients with allergic rhinitis.

The World Allergy Organization journal

Williams DC, Edney G, Maiden B, Smith PK.
PMID: 23663473
World Allergy Organ J. 2013 Feb 12;6(1):4. doi: 10.1186/1939-4551-6-4.

AIMS: To identify the incidence of allergic conjunctivitis in patients with allergic rhinitis.METHODS: One hundred and eighty seven consecutive patients with allergic rhinitis (AR) were directly questioned if they have allergic conjunctivitis (AC) and this was clarified using standard...

Borrowing hydrogen: a catalytic route to C-C bond formation from alcohols.

Chemical communications (Cambridge, England)

Edwards MG, Jazzar RF, Paine BM, Shermer DJ, Whittlesey MK, Williams JM, Edney DD.
PMID: 14737346
Chem Commun (Camb). 2004 Jan 07;(1):90-1. doi: 10.1039/b312162c. Epub 2003 Nov 18.

Ruthenium complexes have been shown to perform efficient transfer hydrogenation reactions between alcohols and alkenes; in combination with an in situ Wittig reaction, indirect formation of C-C bonds has been achieved from alcohols.

Efficient high-order analysis of bowtie nanoantennas using the locally corrected Nyström method.

Optics express

Chorsi HT, Gedney SD.
PMID: 26698770
Opt Express. 2015 Nov 30;23(24):31452-9. doi: 10.1364/OE.23.031452.

It is demonstrated that the Locally Corrected Nyström (LCN) method is a versatile and numerically efficient computational method for the modeling of scattering from plasmonic bowtie nanoantennas. The LCN method is a high-order analysis method that can provide exponential...

Revisiting transthyretin related cardiac amyloidosis: Case report and review of literature.

Clinics and practice

Sharma M, Koman E, Ledley GS, Cho SH.
PMID: 30069298
Clin Pract. 2018 May 16;8(2):1054. doi: 10.4081/cp.2018.1054. eCollection 2018 Mar 28.

Amyloidosis is a complex group of disorders that can involve many organs and cause their dysfunction. Cardiac involvement indicates worse prognosis and influences treatment strategies. Cardiac amyloidosis is an under-diagnosed entity and high index of clinical suspicion and careful...

Distribution and Diversity of .

Microorganisms

Kazartsev IA, Lednev GR.
PMID: 34210043
Microorganisms. 2021 Jun 29;9(7). doi: 10.3390/microorganisms9071409.

The distribution and genetic diversity of 91 of

[Surgical education in the fifth year of medical school; practice].

Khirurgiia

LERNER GD.
PMID: 13045353
Khirurgiia (Mosk). 1953 Jan;27(1):61-6.

No abstract available.

We Don't Have to Lose STEM Students to Business.

Journal of microbiology & biology education

Wernick NLB, Ledley FD.
PMID: 32431771
J Microbiol Biol Educ. 2020 Apr 30;21(1). doi: 10.1128/jmbe.v21i1.2095. eCollection 2020.

Most undergraduate students who leave STEM majors before graduation choose careers in business. This article argues that better integrating business opportunities and context into the STEM curriculum could advance STEM learning, motivate students to remain in STEM as majors,...

Showing 1 to 12 of 14 entries