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Neurons versus herpes simplex virus: the innate immune interactions that contribute to a host-pathogen standoff.

Future virology

Rosato PC, Leib DA.
PMID: 26213562
Future Virol. 2015 Jun;10(6):699-714. doi: 10.2217/fvl.15.45.

Herpes simplex virus (HSV) is a prevalent neurotropic virus, which establishes lifelong latent infections in the neurons of sensory ganglia. Despite our long-standing knowledge that HSV predominately infects sensory neurons during its life cycle, little is known about the...

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Rosato PC, Leib DA. Neurons versus herpes simplex virus: the innate immune interactions that contribute to a host-pathogen standoff. Future Virol. 2015;10(6):699-714doi: 10.2217/fvl.15.45.
Rosato, P. C., & Leib, D. A. (2015). Neurons versus herpes simplex virus: the innate immune interactions that contribute to a host-pathogen standoff. Future virology, 10(6), 699-714. https://doi.org/10.2217/fvl.15.45
Rosato, Pamela C, and Leib, David A. "Neurons versus herpes simplex virus: the innate immune interactions that contribute to a host-pathogen standoff." Future virology vol. 10,6 (2015): 699-714. doi: https://doi.org/10.2217/fvl.15.45
Rosato PC, Leib DA. Neurons versus herpes simplex virus: the innate immune interactions that contribute to a host-pathogen standoff. Future Virol. 2015 Jun;10(6):699-714. doi: 10.2217/fvl.15.45. PMID: 26213562; PMCID: PMC4508759.
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Influence of alpine mountain climate of Bavaria on patients with atopic diseases: studies at the Environmental Research Station Schneefernerhaus (UFS - Zugspitze) - a pilot study.

Clinical and translational allergy

Eberlein B, Huss-Marp J, Pfab F, Fischer R, Franz R, Schlich M, Leibl M, Allertseder V, Liptak J, Kriegisch M, Hennico R, Latotski J, Ebner von Eschenbach C, Darsow U, Buters J, Behrendt H, Huber R, Ring J.
PMID: 26085923
Clin Transl Allergy. 2014 May 08;4:17. doi: 10.1186/2045-7022-4-17. eCollection 2014.

Mountain and maritime climate therapy takes advantage of specific climatic conditions to treat chronic allergic diseases. It was the aim of the study to investigate effects of a 5 day sojourn on atopic diseases at the highest German mountain....

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Eberlein B, Huss-Marp J, Pfab F, et al. Influence of alpine mountain climate of Bavaria on patients with atopic diseases: studies at the Environmental Research Station Schneefernerhaus (UFS - Zugspitze) - a pilot study. Clin Transl Allergy. 2014;4:17doi: 10.1186/2045-7022-4-17.
Eberlein, B., Huss-Marp, J., Pfab, F., Fischer, R., Franz, R., Schlich, M., Leibl, M., Allertseder, V., Liptak, J., Kriegisch, M., Hennico, R., Latotski, J., Ebner von Eschenbach, C., Darsow, U., Buters, J., Behrendt, H., Huber, R., & Ring, J. (2014). Influence of alpine mountain climate of Bavaria on patients with atopic diseases: studies at the Environmental Research Station Schneefernerhaus (UFS - Zugspitze) - a pilot study. Clinical and translational allergy, 417. https://doi.org/10.1186/2045-7022-4-17
Eberlein, Bernadette, et al. "Influence of alpine mountain climate of Bavaria on patients with atopic diseases: studies at the Environmental Research Station Schneefernerhaus (UFS - Zugspitze) - a pilot study." Clinical and translational allergy vol. 4 (2014): 17. doi: https://doi.org/10.1186/2045-7022-4-17
Eberlein B, Huss-Marp J, Pfab F, Fischer R, Franz R, Schlich M, Leibl M, Allertseder V, Liptak J, Kriegisch M, Hennico R, Latotski J, Ebner von Eschenbach C, Darsow U, Buters J, Behrendt H, Huber R, Ring J. Influence of alpine mountain climate of Bavaria on patients with atopic diseases: studies at the Environmental Research Station Schneefernerhaus (UFS - Zugspitze) - a pilot study. Clin Transl Allergy. 2014 May 08;4:17. doi: 10.1186/2045-7022-4-17. eCollection 2014. PMID: 26085923; PMCID: PMC4470350.
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Parental Evaluation of a Nurse Practitioner-Developed Pediatric Neurosurgery Website.

JMIR research protocols

Vogel TK, Kleib M, Davidson SJ, Scott SD.
PMID: 27072930
JMIR Res Protoc. 2016 Apr 12;5(2):e55. doi: 10.2196/resprot.5156.

BACKGROUND: Parents often turn to the Internet to seek health information about their child's diagnosis and condition. Information, support, and resources regarding pediatric neurosurgery are scarce, hard to find, and difficult to comprehend. To address this gap, a pediatric...

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Vogel TK, Kleib M, Davidson SJ, et al. Parental Evaluation of a Nurse Practitioner-Developed Pediatric Neurosurgery Website. JMIR Res Protoc. 2016;5(2):e55doi: 10.2196/resprot.5156.
Vogel, T. K., Kleib, M., Davidson, S. J., & Scott, S. D. (2016). Parental Evaluation of a Nurse Practitioner-Developed Pediatric Neurosurgery Website. JMIR research protocols, 5(2), e55. https://doi.org/10.2196/resprot.5156
Vogel, Tina Kovacs, et al. "Parental Evaluation of a Nurse Practitioner-Developed Pediatric Neurosurgery Website." JMIR research protocols vol. 5,2 (2016): e55. doi: https://doi.org/10.2196/resprot.5156
Vogel TK, Kleib M, Davidson SJ, Scott SD. Parental Evaluation of a Nurse Practitioner-Developed Pediatric Neurosurgery Website. JMIR Res Protoc. 2016 Apr 12;5(2):e55. doi: 10.2196/resprot.5156. PMID: 27072930; PMCID: PMC4846784.
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Next generation sequencing-based copy number analysis reveals low prevalence of deletions and duplications in 46 genes associated with genetic cardiomyopathies.

Molecular genetics & genomic medicine

Ceyhan-Birsoy O, Pugh TJ, Bowser MJ, Hynes E, Frisella AL, Mahanta LM, Lebo MS, Amr SS, Funke BH.
PMID: 27066507
Mol Genet Genomic Med. 2015 Dec 16;4(2):143-51. doi: 10.1002/mgg3.187. eCollection 2016 Mar.

BACKGROUND: Diagnostic testing for genetic cardiomyopathies has undergone dramatic changes in the last decade with next generation sequencing (NGS) expanding the number of genes that can be interrogated simultaneously. Exon resolution copy number analysis is increasingly incorporated into routine...

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Ceyhan-Birsoy O, Pugh TJ, Bowser MJ, et al. Next generation sequencing-based copy number analysis reveals low prevalence of deletions and duplications in 46 genes associated with genetic cardiomyopathies. Mol Genet Genomic Med. 2015;4(2):143-51doi: 10.1002/mgg3.187.
Ceyhan-Birsoy, O., Pugh, T. J., Bowser, M. J., Hynes, E., Frisella, A. L., Mahanta, L. M., Lebo, M. S., Amr, S. S., & Funke, B. H. (2016). Next generation sequencing-based copy number analysis reveals low prevalence of deletions and duplications in 46 genes associated with genetic cardiomyopathies. Molecular genetics & genomic medicine, 4(2), 143-51. https://doi.org/10.1002/mgg3.187
Ceyhan-Birsoy, Ozge, et al. "Next generation sequencing-based copy number analysis reveals low prevalence of deletions and duplications in 46 genes associated with genetic cardiomyopathies." Molecular genetics & genomic medicine vol. 4,2 (2016): 143-51. doi: https://doi.org/10.1002/mgg3.187
Ceyhan-Birsoy O, Pugh TJ, Bowser MJ, Hynes E, Frisella AL, Mahanta LM, Lebo MS, Amr SS, Funke BH. Next generation sequencing-based copy number analysis reveals low prevalence of deletions and duplications in 46 genes associated with genetic cardiomyopathies. Mol Genet Genomic Med. 2015 Dec 16;4(2):143-51. doi: 10.1002/mgg3.187. eCollection 2016 Mar. PMID: 27066507; PMCID: PMC4799872.
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CORRIGENDUM: Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity.

Genetics in medicine : official journal of the American College of Medical Genetics

Alfares AA, Kelly MA, McDermott G, Funke BH, Lebo MS, Baxter SB, Shen J, McLaughlin HM, Clark EH, Babb LJ, Cox SW, DePalma SR, Ho CY, Seidman JG, Seidman CE, Rehm HL.
PMID: 25835197
Genet Med. 2015 Apr;17(4):319. doi: 10.1038/gim.2015.16.

Genet Med advance online publication, January 22, 2015; doi:10.1038/gim.2014.205. In the Advance Online Publication version, of this article, there is a mistake on page 2 in the first paragraph of the Materials and Methods section. The sentence beginning "Among...

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Alfares AA, Kelly MA, McDermott G, et al. CORRIGENDUM: Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity. Genet Med. 2015;17(4):319doi: 10.1038/gim.2015.16.
Alfares, A. A., Kelly, M. A., McDermott, G., Funke, B. H., Lebo, M. S., Baxter, S. B., Shen, J., McLaughlin, H. M., Clark, E. H., Babb, L. J., Cox, S. W., DePalma, S. R., Ho, C. Y., Seidman, J. G., Seidman, C. E., & Rehm, H. L. (2015). CORRIGENDUM: Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity. Genetics in medicine : official journal of the American College of Medical Genetics, 17(4), 319. https://doi.org/10.1038/gim.2015.16
Alfares, Ahmed A, et al. "CORRIGENDUM: Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity." Genetics in medicine : official journal of the American College of Medical Genetics vol. 17,4 (2015): 319. doi: https://doi.org/10.1038/gim.2015.16
Alfares AA, Kelly MA, McDermott G, Funke BH, Lebo MS, Baxter SB, Shen J, McLaughlin HM, Clark EH, Babb LJ, Cox SW, DePalma SR, Ho CY, Seidman JG, Seidman CE, Rehm HL. CORRIGENDUM: Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity. Genet Med. 2015 Apr;17(4):319. doi: 10.1038/gim.2015.16. PMID: 25835197.
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The effect of dose and concentration on D-xylose absorption in healthy, immature dogs.

Veterinary clinical pathology

Nix BE, Leib MS, Zajac A, Zarakas K.
PMID: 12669282
Vet Clin Pathol. 1993;22(1):10-16. doi: 10.1111/j.1939-165x.1993.tb00870.x.

Nine combinations of dosages and concentrations of D-xylose were given orally to eight clinically normal, immature dogs. The concentrations and dosages of D-xylose consisted of 5%, 10%, and 20% at 250 mg/kg, 500 mg/kg, and 750 mg/kg. Serum samples...

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Nix BE, Leib MS, Zajac A, et al. The effect of dose and concentration on D-xylose absorption in healthy, immature dogs. Vet Clin Pathol. 1993;22(1):10-16doi: 10.1111/j.1939-165x.1993.tb00870.x.
Nix, B. E., Leib, M. S., Zajac, A., & Zarakas, K. (1993). The effect of dose and concentration on D-xylose absorption in healthy, immature dogs. Veterinary clinical pathology, 22(1), 10-16. https://doi.org/10.1111/j.1939-165x.1993.tb00870.x
Nix, Beverlee E., et al. "The effect of dose and concentration on D-xylose absorption in healthy, immature dogs." Veterinary clinical pathology vol. 22,1 (1993): 10-16. doi: https://doi.org/10.1111/j.1939-165x.1993.tb00870.x
Nix BE, Leib MS, Zajac A, Zarakas K. The effect of dose and concentration on D-xylose absorption in healthy, immature dogs. Vet Clin Pathol. 1993;22(1):10-16. doi: 10.1111/j.1939-165x.1993.tb00870.x. PMID: 12669282.
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High-throughput screening of selectivity of melt polymerization catalysts using fluorescence spectroscopy and two-wavelength fluorescence imaging.

Analytical chemistry

Potyrailo RA, Lemmon JP, Leib TK.
PMID: 14632080
Anal Chem. 2003 Sep 01;75(17):4676-81. doi: 10.1021/ac034296d.

A new general approach for rapid assessment of polymerization catalysts is introduced. Native fluorescence emission of solid polymers is measured directly in combinatorial 96-microreactor arrays and polymers produced in a laboratory-scale validation reactor. Fluorescence features collected with a CCD-based...

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Potyrailo RA, Lemmon JP, Leib TK. High-throughput screening of selectivity of melt polymerization catalysts using fluorescence spectroscopy and two-wavelength fluorescence imaging. Anal Chem. 2003;75(17):4676-81doi: 10.1021/ac034296d.
Potyrailo, R. A., Lemmon, J. P., & Leib, T. K. (2003). High-throughput screening of selectivity of melt polymerization catalysts using fluorescence spectroscopy and two-wavelength fluorescence imaging. Analytical chemistry, 75(17), 4676-81. https://doi.org/10.1021/ac034296d
Potyrailo, Radislav A, et al. "High-throughput screening of selectivity of melt polymerization catalysts using fluorescence spectroscopy and two-wavelength fluorescence imaging." Analytical chemistry vol. 75,17 (2003): 4676-81. doi: https://doi.org/10.1021/ac034296d
Potyrailo RA, Lemmon JP, Leib TK. High-throughput screening of selectivity of melt polymerization catalysts using fluorescence spectroscopy and two-wavelength fluorescence imaging. Anal Chem. 2003 Sep 01;75(17):4676-81. doi: 10.1021/ac034296d. PMID: 14632080.
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Average sequential water molecule binding enthalpies of M(H2O)(19-124)2+ (M = Co, Fe, Mn, and Cu) measured with ultraviolet photodissociation at 193 and 248 nm.

The journal of physical chemistry. A

Donald WA, Leib RD, Demireva M, Negru B, Neumark DM, Williams ER.
PMID: 21142113
J Phys Chem A. 2011 Jan 13;115(1):2-12. doi: 10.1021/jp107547r. Epub 2010 Dec 13.

The average sequential water molecule binding enthalpies to large water clusters (between 19 and 124 water molecules) containing divalent ions were obtained by measuring the average number of water molecules lost upon absorption of an UV photon (193 or...

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Donald WA, Leib RD, Demireva M, et al. Average sequential water molecule binding enthalpies of M(H2O)(19-124)2+ (M = Co, Fe, Mn, and Cu) measured with ultraviolet photodissociation at 193 and 248 nm. J Phys Chem A. 2010;115(1):2-12doi: 10.1021/jp107547r.
Donald, W. A., Leib, R. D., Demireva, M., Negru, B., Neumark, D. M., & Williams, E. R. (2011). Average sequential water molecule binding enthalpies of M(H2O)(19-124)2+ (M = Co, Fe, Mn, and Cu) measured with ultraviolet photodissociation at 193 and 248 nm. The journal of physical chemistry. A, 115(1), 2-12. https://doi.org/10.1021/jp107547r
Donald, William A, et al. "Average sequential water molecule binding enthalpies of M(H2O)(19-124)2+ (M = Co, Fe, Mn, and Cu) measured with ultraviolet photodissociation at 193 and 248 nm." The journal of physical chemistry. A vol. 115,1 (2011): 2-12. doi: https://doi.org/10.1021/jp107547r
Donald WA, Leib RD, Demireva M, Negru B, Neumark DM, Williams ER. Average sequential water molecule binding enthalpies of M(H2O)(19-124)2+ (M = Co, Fe, Mn, and Cu) measured with ultraviolet photodissociation at 193 and 248 nm. J Phys Chem A. 2011 Jan 13;115(1):2-12. doi: 10.1021/jp107547r. Epub 2010 Dec 13. PMID: 21142113.
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Maturation of tertiary lymphoid structures and recurrence of stage II and III colorectal cancer.

Oncoimmunology

Posch F, Silina K, Leibl S, Mündlein A, Moch H, Siebenhüner A, Samaras P, Riedl J, Stotz M, Szkandera J, Stöger H, Pichler M, Stupp R, van den Broek M, Schraml P, Gerger A, Petrausch U, Winder T.
PMID: 29416939
Oncoimmunology. 2017 Dec 18;7(2):e1378844. doi: 10.1080/2162402X.2017.1378844. eCollection 2018.

Tertiary lymphoid structures (TLS) are associated with favorable outcome in non-metastatic colorectal carcinoma (nmCRC), but the dynamics of TLS maturation and its association with effective anti-tumor immune surveillance in nmCRC are unclear. Here, we hypothesized that not only the...

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Posch F, Silina K, Leibl S, et al. Maturation of tertiary lymphoid structures and recurrence of stage II and III colorectal cancer. Oncoimmunology. 2017;7(2):e1378844doi: 10.1080/2162402X.2017.1378844.
Posch, F., Silina, K., Leibl, S., Mündlein, A., Moch, H., Siebenhüner, A., Samaras, P., Riedl, J., Stotz, M., Szkandera, J., Stöger, H., Pichler, M., Stupp, R., van den Broek, M., Schraml, P., Gerger, A., Petrausch, U., & Winder, T. (2018). Maturation of tertiary lymphoid structures and recurrence of stage II and III colorectal cancer. Oncoimmunology, 7(2), e1378844. https://doi.org/10.1080/2162402X.2017.1378844
Posch, Florian, et al. "Maturation of tertiary lymphoid structures and recurrence of stage II and III colorectal cancer." Oncoimmunology vol. 7,2 (2018): e1378844. doi: https://doi.org/10.1080/2162402X.2017.1378844
Posch F, Silina K, Leibl S, Mündlein A, Moch H, Siebenhüner A, Samaras P, Riedl J, Stotz M, Szkandera J, Stöger H, Pichler M, Stupp R, van den Broek M, Schraml P, Gerger A, Petrausch U, Winder T. Maturation of tertiary lymphoid structures and recurrence of stage II and III colorectal cancer. Oncoimmunology. 2017 Dec 18;7(2):e1378844. doi: 10.1080/2162402X.2017.1378844. eCollection 2018. PMID: 29416939; PMCID: PMC5798199.
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HiMAP: Robust phylogenomics from highly multiplexed amplicon sequencing.

Molecular ecology resources

Dupuis JR, Bremer FT, Kauwe A, San Jose M, Leblanc L, Rubinoff D, Geib SM.
PMID: 29633537
Mol Ecol Resour. 2018 Apr 06; doi: 10.1111/1755-0998.12783. Epub 2018 Apr 06.

High-throughput sequencing has fundamentally changed how molecular phylogenetic data sets are assembled, and phylogenomic data sets commonly contain 50- to 100-fold more loci than those generated using traditional Sanger sequencing-based approaches. Here, we demonstrate a new approach for building...

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Dupuis JR, Bremer FT, Kauwe A, et al. HiMAP: Robust phylogenomics from highly multiplexed amplicon sequencing. Mol Ecol Resour. 2018;doi: 10.1111/1755-0998.12783.
Dupuis, J. R., Bremer, F. T., Kauwe, A., San Jose, M., Leblanc, L., Rubinoff, D., & Geib, S. M. (2018). HiMAP: Robust phylogenomics from highly multiplexed amplicon sequencing. Molecular ecology resources, . https://doi.org/10.1111/1755-0998.12783
Dupuis, Julian R, et al. "HiMAP: Robust phylogenomics from highly multiplexed amplicon sequencing." Molecular ecology resources vol. (2018). doi: https://doi.org/10.1111/1755-0998.12783
Dupuis JR, Bremer FT, Kauwe A, San Jose M, Leblanc L, Rubinoff D, Geib SM. HiMAP: Robust phylogenomics from highly multiplexed amplicon sequencing. Mol Ecol Resour. 2018 Apr 06; doi: 10.1111/1755-0998.12783. Epub 2018 Apr 06. PMID: 29633537.
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Genome Annotation Generator: a simple tool for generating and correcting WGS annotation tables for NCBI submission.

GigaScience

Geib SM, Hall B, Derego T, Bremer FT, Cannoles K, Sim SB.
PMID: 29635297
Gigascience. 2018 Apr 01;7(4):1-5. doi: 10.1093/gigascience/giy018.

BACKGROUND: One of the most overlooked, yet critical, components of a whole genome sequencing (WGS) project is the submission and curation of the data to a genomic repository, most commonly the National Center for Biotechnology Information (NCBI). While large...

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Geib SM, Hall B, Derego T, et al. Genome Annotation Generator: a simple tool for generating and correcting WGS annotation tables for NCBI submission. Gigascience. 2018;7(4):1-5doi: 10.1093/gigascience/giy018.
Geib, S. M., Hall, B., Derego, T., Bremer, F. T., Cannoles, K., & Sim, S. B. (2018). Genome Annotation Generator: a simple tool for generating and correcting WGS annotation tables for NCBI submission. GigaScience, 7(4), 1-5. https://doi.org/10.1093/gigascience/giy018
Geib, Scott M, et al. "Genome Annotation Generator: a simple tool for generating and correcting WGS annotation tables for NCBI submission." GigaScience vol. 7,4 (2018): 1-5. doi: https://doi.org/10.1093/gigascience/giy018
Geib SM, Hall B, Derego T, Bremer FT, Cannoles K, Sim SB. Genome Annotation Generator: a simple tool for generating and correcting WGS annotation tables for NCBI submission. Gigascience. 2018 Apr 01;7(4):1-5. doi: 10.1093/gigascience/giy018. PMID: 29635297; PMCID: PMC5887294.
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Bioinformatics Workflow for Clinical Whole Genome Sequencing at Partners HealthCare Personalized Medicine.

Journal of personalized medicine

Tsai EA, Shakbatyan R, Evans J, Rossetti P, Graham C, Sharma H, Lin CF, Lebo MS.
PMID: 26927186
J Pers Med. 2016 Feb 27;6(1). doi: 10.3390/jpm6010012.

Effective implementation of precision medicine will be enhanced by a thorough understanding of each patient's genetic composition to better treat his or her presenting symptoms or mitigate the onset of disease. This ideally includes the sequence information of a...

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Tsai EA, Shakbatyan R, Evans J, et al. Bioinformatics Workflow for Clinical Whole Genome Sequencing at Partners HealthCare Personalized Medicine. J Pers Med. 2016;6(1)doi: 10.3390/jpm6010012.
Tsai, E. A., Shakbatyan, R., Evans, J., Rossetti, P., Graham, C., Sharma, H., Lin, C. F., & Lebo, M. S. (2016). Bioinformatics Workflow for Clinical Whole Genome Sequencing at Partners HealthCare Personalized Medicine. Journal of personalized medicine, 6(1), . https://doi.org/10.3390/jpm6010012
Tsai, Ellen A, et al. "Bioinformatics Workflow for Clinical Whole Genome Sequencing at Partners HealthCare Personalized Medicine." Journal of personalized medicine vol. 6,1 (2016). doi: https://doi.org/10.3390/jpm6010012
Tsai EA, Shakbatyan R, Evans J, Rossetti P, Graham C, Sharma H, Lin CF, Lebo MS. Bioinformatics Workflow for Clinical Whole Genome Sequencing at Partners HealthCare Personalized Medicine. J Pers Med. 2016 Feb 27;6(1). doi: 10.3390/jpm6010012. PMID: 26927186; PMCID: PMC4810391.
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