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Interleukin 13- and interleukin 17A-induced pulmonary hypertension phenotype due to inhalation of antigen and fine particles from air pollution.

Pulmonary circulation

Park SH, Chen WC, Esmaeil N, Lucas B, Marsh LM, Reibman J, Grunig G.
PMID: 25610601
Pulm Circ. 2014 Dec;4(4):654-68. doi: 10.1086/678511.

Pulmonary hypertension has a marked detrimental effect on quality of life and life expectancy. In a mouse model of antigen-induced pulmonary arterial remodeling, we have recently shown that coexposure to urban ambient particulate matter (PM) significantly increased the thickening...

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Park SH, Chen WC, Esmaeil N, et al. Interleukin 13- and interleukin 17A-induced pulmonary hypertension phenotype due to inhalation of antigen and fine particles from air pollution. Pulm Circ. 2014;4(4):654-68doi: 10.1086/678511.
Park, S. H., Chen, W. C., Esmaeil, N., Lucas, B., Marsh, L. M., Reibman, J., & Grunig, G. (2014). Interleukin 13- and interleukin 17A-induced pulmonary hypertension phenotype due to inhalation of antigen and fine particles from air pollution. Pulmonary circulation, 4(4), 654-68. https://doi.org/10.1086/678511
Park, Sung-Hyun, et al. "Interleukin 13- and interleukin 17A-induced pulmonary hypertension phenotype due to inhalation of antigen and fine particles from air pollution." Pulmonary circulation vol. 4,4 (2014): 654-68. doi: https://doi.org/10.1086/678511
Park SH, Chen WC, Esmaeil N, Lucas B, Marsh LM, Reibman J, Grunig G. Interleukin 13- and interleukin 17A-induced pulmonary hypertension phenotype due to inhalation of antigen and fine particles from air pollution. Pulm Circ. 2014 Dec;4(4):654-68. doi: 10.1086/678511. PMID: 25610601; PMCID: PMC4278625.
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Perspective: ambient air pollution: inflammatory response and effects on the lung's vasculature.

Pulmonary circulation

Grunig G, Marsh LM, Esmaeil N, Jackson K, Gordon T, Reibman J, Kwapiszewska G, Park SH.
PMID: 25006418
Pulm Circ. 2014 Mar;4(1):25-35. doi: 10.1086/674902.

Particulates from air pollution are implicated in causing or exacerbating respiratory and systemic cardiovascular diseases and are thought to be among the leading causes of morbidity and mortality. However, the contribution of ambient particulate matter to diseases affecting the...

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Grunig G, Marsh LM, Esmaeil N, et al. Perspective: ambient air pollution: inflammatory response and effects on the lung's vasculature. Pulm Circ. 2014;4(1):25-35doi: 10.1086/674902.
Grunig, G., Marsh, L. M., Esmaeil, N., Jackson, K., Gordon, T., Reibman, J., Kwapiszewska, G., & Park, S. H. (2014). Perspective: ambient air pollution: inflammatory response and effects on the lung's vasculature. Pulmonary circulation, 4(1), 25-35. https://doi.org/10.1086/674902
Grunig, Gabriele, et al. "Perspective: ambient air pollution: inflammatory response and effects on the lung's vasculature." Pulmonary circulation vol. 4,1 (2014): 25-35. doi: https://doi.org/10.1086/674902
Grunig G, Marsh LM, Esmaeil N, Jackson K, Gordon T, Reibman J, Kwapiszewska G, Park SH. Perspective: ambient air pollution: inflammatory response and effects on the lung's vasculature. Pulm Circ. 2014 Mar;4(1):25-35. doi: 10.1086/674902. PMID: 25006418; PMCID: PMC4070766.
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Transposon insertion mapping with PIMMS - Pragmatic Insertional Mutation Mapping System.

Frontiers in genetics

Blanchard AM, Leigh JA, Egan SA, Emes RD.
PMID: 25914720
Front Genet. 2015 Apr 09;6:139. doi: 10.3389/fgene.2015.00139. eCollection 2015.

UNLABELLED: The PIMMS (Pragmatic Insertional Mutation Mapping System) pipeline has been developed for simple conditionally essential genome discovery experiments in bacteria. Capable of using raw sequence data files alongside a FASTA sequence of the reference genome and GFF file,...

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Blanchard AM, Leigh JA, Egan SA, et al. Transposon insertion mapping with PIMMS - Pragmatic Insertional Mutation Mapping System. Front Genet. 2015;6:139doi: 10.3389/fgene.2015.00139.
Blanchard, A. M., Leigh, J. A., Egan, S. A., & Emes, R. D. (2015). Transposon insertion mapping with PIMMS - Pragmatic Insertional Mutation Mapping System. Frontiers in genetics, 6139. https://doi.org/10.3389/fgene.2015.00139
Blanchard, Adam M, et al. "Transposon insertion mapping with PIMMS - Pragmatic Insertional Mutation Mapping System." Frontiers in genetics vol. 6 (2015): 139. doi: https://doi.org/10.3389/fgene.2015.00139
Blanchard AM, Leigh JA, Egan SA, Emes RD. Transposon insertion mapping with PIMMS - Pragmatic Insertional Mutation Mapping System. Front Genet. 2015 Apr 09;6:139. doi: 10.3389/fgene.2015.00139. eCollection 2015. PMID: 25914720; PMCID: PMC4391243.
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Photoinduction of fast, reversible translational motion in a hydrogen-bonded molecular shuttle.

Science (New York, N.Y.)

Brouwer AM, Frochot C, Gatti FG, Leigh DA, Mottier L, Paolucci F, Roffia S, Wurpel GW.
PMID: 11251112
Science. 2001 Mar 16;291(5511):2124-8. doi: 10.1126/science.1057886. Epub 2001 Feb 22.

A rotaxane is described in which a macrocycle moves reversibly between two hydrogen-bonding stations after a nanosecond laser pulse. Observation of transient changes in the optical absorption spectrum after photoexcitation allows direct quantitative monitoring of the submolecular translational process....

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Brouwer AM, Frochot C, Gatti FG, et al. Photoinduction of fast, reversible translational motion in a hydrogen-bonded molecular shuttle. Science. 2001;291(5511):2124-8doi: 10.1126/science.1057886.
Brouwer, A. M., Frochot, C., Gatti, F. G., Leigh, D. A., Mottier, L., Paolucci, F., Roffia, S., & Wurpel, G. W. (2001). Photoinduction of fast, reversible translational motion in a hydrogen-bonded molecular shuttle. Science (New York, N.Y.), 291(5511), 2124-8. https://doi.org/10.1126/science.1057886
Brouwer, A M, et al. "Photoinduction of fast, reversible translational motion in a hydrogen-bonded molecular shuttle." Science (New York, N.Y.) vol. 291,5511 (2001): 2124-8. doi: https://doi.org/10.1126/science.1057886
Brouwer AM, Frochot C, Gatti FG, Leigh DA, Mottier L, Paolucci F, Roffia S, Wurpel GW. Photoinduction of fast, reversible translational motion in a hydrogen-bonded molecular shuttle. Science. 2001 Mar 16;291(5511):2124-8. doi: 10.1126/science.1057886. Epub 2001 Feb 22. PMID: 11251112.
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Mechanically linked polycarbonate.

Journal of the American Chemical Society

Fustin CA, Bailly C, Clarkson GJ, De Groote P, Galow TH, Leigh DA, Robertson D, Slawin AM, Wong JK.
PMID: 12590548
J Am Chem Soc. 2003 Feb 26;125(8):2200-7. doi: 10.1021/ja0292546.

The synthesis, by solid-state copolymerization, and characterization of the first polycatenanes based on a commercial polymer are reported. Various amounts of a benzylic amide [2]catenane, the corresponding macrocycle, and a rigid bisphenol fluorene derivative have been quantitatively and homogeneously...

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Fustin CA, Bailly C, Clarkson GJ, et al. Mechanically linked polycarbonate. J Am Chem Soc. 2003;125(8):2200-7doi: 10.1021/ja0292546.
Fustin, C. A., Bailly, C., Clarkson, G. J., De Groote, P., Galow, T. H., Leigh, D. A., Robertson, D., Slawin, A. M., & Wong, J. K. (2003). Mechanically linked polycarbonate. Journal of the American Chemical Society, 125(8), 2200-7. https://doi.org/10.1021/ja0292546
Fustin, Charles-André, et al. "Mechanically linked polycarbonate." Journal of the American Chemical Society vol. 125,8 (2003): 2200-7. doi: https://doi.org/10.1021/ja0292546
Fustin CA, Bailly C, Clarkson GJ, De Groote P, Galow TH, Leigh DA, Robertson D, Slawin AM, Wong JK. Mechanically linked polycarbonate. J Am Chem Soc. 2003 Feb 26;125(8):2200-7. doi: 10.1021/ja0292546. PMID: 12590548.
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"Magic rod" rotaxanes: the hydrogen bond-directed synthesis of molecular shuttles under thermodynamic control.

Organic letters

Hannam JS, Kidd TJ, Leigh DA, Wilson AJ.
PMID: 12762683
Org Lett. 2003 May 29;5(11):1907-10. doi: 10.1021/ol0344927.

[reaction: see text] Peptide [2]- and [3]rotaxanes are assembled in high yields under thermodynamic control using hydrogen bonding interactions and reversible cross olefin metathesis.

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Hannam JS, Kidd TJ, Leigh DA, et al. "Magic rod" rotaxanes: the hydrogen bond-directed synthesis of molecular shuttles under thermodynamic control. Org Lett. 2003;5(11):1907-10doi: 10.1021/ol0344927.
Hannam, J. S., Kidd, T. J., Leigh, D. A., & Wilson, A. J. (2003). "Magic rod" rotaxanes: the hydrogen bond-directed synthesis of molecular shuttles under thermodynamic control. Organic letters, 5(11), 1907-10. https://doi.org/10.1021/ol0344927
Hannam, Jeffrey S, et al. ""Magic rod" rotaxanes: the hydrogen bond-directed synthesis of molecular shuttles under thermodynamic control." Organic letters vol. 5,11 (2003): 1907-10. doi: https://doi.org/10.1021/ol0344927
Hannam JS, Kidd TJ, Leigh DA, Wilson AJ. "Magic rod" rotaxanes: the hydrogen bond-directed synthesis of molecular shuttles under thermodynamic control. Org Lett. 2003 May 29;5(11):1907-10. doi: 10.1021/ol0344927. PMID: 12762683.
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Rotaxane building blocks bearing blocked isocyanate stoppers: polyrotaxanes through post-assembly chain extension.

Angewandte Chemie (International ed. in English)

Kidd TJ, Loontjens TJ, Leigh DA, Wong JK.
PMID: 12888963
Angew Chem Int Ed Engl. 2003 Jul 28;42(29):3379-83. doi: 10.1002/anie.200351458.

No abstract available.

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Kidd TJ, Loontjens TJ, Leigh DA, et al. Rotaxane building blocks bearing blocked isocyanate stoppers: polyrotaxanes through post-assembly chain extension. Angew Chem Int Ed Engl. 2003;42(29):3379-83doi: 10.1002/anie.200351458.
Kidd, T. J., Loontjens, T. J., Leigh, D. A., & Wong, J. K. (2003). Rotaxane building blocks bearing blocked isocyanate stoppers: polyrotaxanes through post-assembly chain extension. Angewandte Chemie (International ed. in English), 42(29), 3379-83. https://doi.org/10.1002/anie.200351458
Kidd, Timothy J, et al. "Rotaxane building blocks bearing blocked isocyanate stoppers: polyrotaxanes through post-assembly chain extension." Angewandte Chemie (International ed. in English) vol. 42,29 (2003): 3379-83. doi: https://doi.org/10.1002/anie.200351458
Kidd TJ, Loontjens TJ, Leigh DA, Wong JK. Rotaxane building blocks bearing blocked isocyanate stoppers: polyrotaxanes through post-assembly chain extension. Angew Chem Int Ed Engl. 2003 Jul 28;42(29):3379-83. doi: 10.1002/anie.200351458. PMID: 12888963.
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Wave energy and intertidal productivity.

Proceedings of the National Academy of Sciences of the United States of America

Leigh EG, Paine RT, Quinn JF, Suchanek TH.
PMID: 16593813
Proc Natl Acad Sci U S A. 1987 Mar;84(5):1314-8. doi: 10.1073/pnas.84.5.1314.

In the northeastern Pacific, intertidal zones of the most wave-beaten shores receive more energy from breaking waves than from the sun. Despite severe mortality from winter storms, communities at some wave-beaten sites produce an extraordinary quantity of dry matter...

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Leigh EG, Paine RT, Quinn JF, et al. Wave energy and intertidal productivity. Proc Natl Acad Sci U S A. 1987;84(5):1314-8doi: 10.1073/pnas.84.5.1314.
Leigh, E. G., Paine, R. T., Quinn, J. F., & Suchanek, T. H. (1987). Wave energy and intertidal productivity. Proceedings of the National Academy of Sciences of the United States of America, 84(5), 1314-8. https://doi.org/10.1073/pnas.84.5.1314
Leigh, E G, et al. "Wave energy and intertidal productivity." Proceedings of the National Academy of Sciences of the United States of America vol. 84,5 (1987): 1314-8. doi: https://doi.org/10.1073/pnas.84.5.1314
Leigh EG, Paine RT, Quinn JF, Suchanek TH. Wave energy and intertidal productivity. Proc Natl Acad Sci U S A. 1987 Mar;84(5):1314-8. doi: 10.1073/pnas.84.5.1314. PMID: 16593813; PMCID: PMC304418.
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When does the good of the group override the advantage of the individual?.

Proceedings of the National Academy of Sciences of the United States of America

Leigh EG.
PMID: 16593312
Proc Natl Acad Sci U S A. 1983 May;80(10):2985-9. doi: 10.1073/pnas.80.10.2985.

In a system of N populations of n reproductive individuals apiece, in which each population has constant variance v(2) and lasts L generations, group selection on a quantitative character has a reasonable chance of overriding selection within populations if...

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Leigh EG. When does the good of the group override the advantage of the individual?. Proc Natl Acad Sci U S A. 1983;80(10):2985-9doi: 10.1073/pnas.80.10.2985.
Leigh, E. G. (1983). When does the good of the group override the advantage of the individual?. Proceedings of the National Academy of Sciences of the United States of America, 80(10), 2985-9. https://doi.org/10.1073/pnas.80.10.2985
Leigh, E G. "When does the good of the group override the advantage of the individual?." Proceedings of the National Academy of Sciences of the United States of America vol. 80,10 (1983): 2985-9. doi: https://doi.org/10.1073/pnas.80.10.2985
Leigh EG. When does the good of the group override the advantage of the individual?. Proc Natl Acad Sci U S A. 1983 May;80(10):2985-9. doi: 10.1073/pnas.80.10.2985. PMID: 16593312; PMCID: PMC393958.
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Shaping of a conformationally flexible molecular structure for spectroscopy.

Angewandte Chemie (International ed. in English)

Rijs AM, Crews BO, de Vries MS, Hannam JS, Leigh DA, Fanti M, Zerbetto F, Buma WJ.
PMID: 18351607
Angew Chem Int Ed Engl. 2008;47(17):3174-9. doi: 10.1002/anie.200705627.

No abstract available.

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Rijs AM, Crews BO, de Vries MS, et al. Shaping of a conformationally flexible molecular structure for spectroscopy. Angew Chem Int Ed Engl. 2008;47(17):3174-9doi: 10.1002/anie.200705627.
Rijs, A. M., Crews, B. O., de Vries, M. S., Hannam, J. S., Leigh, D. A., Fanti, M., Zerbetto, F., & Buma, W. J. (2008). Shaping of a conformationally flexible molecular structure for spectroscopy. Angewandte Chemie (International ed. in English), 47(17), 3174-9. https://doi.org/10.1002/anie.200705627
Rijs, Anouk M, et al. "Shaping of a conformationally flexible molecular structure for spectroscopy." Angewandte Chemie (International ed. in English) vol. 47,17 (2008): 3174-9. doi: https://doi.org/10.1002/anie.200705627
Rijs AM, Crews BO, de Vries MS, Hannam JS, Leigh DA, Fanti M, Zerbetto F, Buma WJ. Shaping of a conformationally flexible molecular structure for spectroscopy. Angew Chem Int Ed Engl. 2008;47(17):3174-9. doi: 10.1002/anie.200705627. PMID: 18351607.
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Self-organization of rotaxane thin films into spatially correlated nanostructures: morphological and structural aspects.

Journal of the American Chemical Society

Moulin JF, Kengne JC, Kshirsagar R, Cavallini M, Biscarini F, León S, Zerbetto F, Bottari G, Leigh DA.
PMID: 16402840
J Am Chem Soc. 2006 Jan 18;128(2):526-32. doi: 10.1021/ja054886o.

The self-organization of rotaxane thin films into spatially correlated nanostructures is shown to occur upon a thermal stimulus. The mechanism of formation of nanostructures and their organization has been investigated using atomic force microscopy, bright field transmission electron microscopy,...

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Moulin JF, Kengne JC, Kshirsagar R, et al. Self-organization of rotaxane thin films into spatially correlated nanostructures: morphological and structural aspects. J Am Chem Soc. 2006;128(2):526-32doi: 10.1021/ja054886o.
Moulin, J. F., Kengne, J. C., Kshirsagar, R., Cavallini, M., Biscarini, F., León, S., Zerbetto, F., Bottari, G., & Leigh, D. A. (2006). Self-organization of rotaxane thin films into spatially correlated nanostructures: morphological and structural aspects. Journal of the American Chemical Society, 128(2), 526-32. https://doi.org/10.1021/ja054886o
Moulin, Jean-François, et al. "Self-organization of rotaxane thin films into spatially correlated nanostructures: morphological and structural aspects." Journal of the American Chemical Society vol. 128,2 (2006): 526-32. doi: https://doi.org/10.1021/ja054886o
Moulin JF, Kengne JC, Kshirsagar R, Cavallini M, Biscarini F, León S, Zerbetto F, Bottari G, Leigh DA. Self-organization of rotaxane thin films into spatially correlated nanostructures: morphological and structural aspects. J Am Chem Soc. 2006 Jan 18;128(2):526-32. doi: 10.1021/ja054886o. PMID: 16402840.
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Shuttling through reversible covalent chemistry.

Chemical communications (Cambridge, England)

Leigh DA, Pérez EM.
PMID: 15489971
Chem Commun (Camb). 2004 Oct 21;(20):2262-3. doi: 10.1039/b412570c. Epub 2004 Sep 23.

The first stimuli-responsive molecular shuttle that functions through reversible C-C bond formation is reported.

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Leigh DA, Pérez EM. Shuttling through reversible covalent chemistry. Chem Commun (Camb). 2004;(20):2262-3doi: 10.1039/b412570c.
Leigh, D. A., & Pérez, E. M. (2004). Shuttling through reversible covalent chemistry. Chemical communications (Cambridge, England), (20), 2262-3. https://doi.org/10.1039/b412570c
Leigh, David A, and Pérez, Emilio M. "Shuttling through reversible covalent chemistry." Chemical communications (Cambridge, England) vol. ,20 (2004): 2262-3. doi: https://doi.org/10.1039/b412570c
Leigh DA, Pérez EM. Shuttling through reversible covalent chemistry. Chem Commun (Camb). 2004 Oct 21;(20):2262-3. doi: 10.1039/b412570c. Epub 2004 Sep 23. PMID: 15489971.
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Showing 1 to 12 of 372 entries