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Showing 1 to 12 of 54 entries
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Signaling From Lysosomes Enhances Mitochondria-Mediated Photodynamic Therapy In Cancer Cells.

Proceedings of SPIE--the International Society for Optical Engineering

Quiogue G, Saggu S, Hung HI, Kenney ME, Oleinick NL, Lemasters JJ, Nieminen AL.
PMID: 20228965
Proc SPIE Int Soc Opt Eng. 2009 Jul 12;7380(73800):1-8. doi: 10.1117/12.823752.

In photodynamic therapy (PDT), visible light activates a photosensitizing drug added to a tissue, resulting in singlet oxygen formation and cell death. Assessed by confocal microscopy, the photosensitizer phthalocyanine 4 (Pc 4) localizes primarily to mitochondrial membranes in cancer...

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Quiogue G, Saggu S, Hung HI, et al. Signaling From Lysosomes Enhances Mitochondria-Mediated Photodynamic Therapy In Cancer Cells. Proc SPIE Int Soc Opt Eng. 2009;7380(73800):1-8doi: 10.1117/12.823752.
Quiogue, G., Saggu, S., Hung, H. I., Kenney, M. E., Oleinick, N. L., Lemasters, J. J., & Nieminen, A. L. (2009). Signaling From Lysosomes Enhances Mitochondria-Mediated Photodynamic Therapy In Cancer Cells. Proceedings of SPIE--the International Society for Optical Engineering, 7380(73800), 1-8. https://doi.org/10.1117/12.823752
Quiogue, Geraldine, et al. "Signaling From Lysosomes Enhances Mitochondria-Mediated Photodynamic Therapy In Cancer Cells." Proceedings of SPIE--the International Society for Optical Engineering vol. 7380,73800 (2009): 1-8. doi: https://doi.org/10.1117/12.823752
Quiogue G, Saggu S, Hung HI, Kenney ME, Oleinick NL, Lemasters JJ, Nieminen AL. Signaling From Lysosomes Enhances Mitochondria-Mediated Photodynamic Therapy In Cancer Cells. Proc SPIE Int Soc Opt Eng. 2009 Jul 12;7380(73800):1-8. doi: 10.1117/12.823752. PMID: 20228965; PMCID: PMC2836728.
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Video fluorescence microscopic techniques to monitor local lipid and phospholipid molecular order and organization in cell membranes during hypoxic injury.

Journal of fluorescence

Wang XF, Florine-Casteel K, Lemasters JJ, Herman B.
PMID: 24226613
J Fluoresc. 1995 Mar;5(1):71-84. doi: 10.1007/BF00718784.

Digitized video microscopy is rapidly finding uses in a number of fields of biological investigation because it allows quantitative assessment of physiological functions in intact cells under a variety of conditions. In this review paper, we focus on the...

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Wang XF, Florine-Casteel K, Lemasters JJ, et al. Video fluorescence microscopic techniques to monitor local lipid and phospholipid molecular order and organization in cell membranes during hypoxic injury. J Fluoresc. 1995;5(1):71-84doi: 10.1007/BF00718784.
Wang, X. F., Florine-Casteel, K., Lemasters, J. J., & Herman, B. (1995). Video fluorescence microscopic techniques to monitor local lipid and phospholipid molecular order and organization in cell membranes during hypoxic injury. Journal of fluorescence, 5(1), 71-84. https://doi.org/10.1007/BF00718784
Wang, X F, et al. "Video fluorescence microscopic techniques to monitor local lipid and phospholipid molecular order and organization in cell membranes during hypoxic injury." Journal of fluorescence vol. 5,1 (1995): 71-84. doi: https://doi.org/10.1007/BF00718784
Wang XF, Florine-Casteel K, Lemasters JJ, Herman B. Video fluorescence microscopic techniques to monitor local lipid and phospholipid molecular order and organization in cell membranes during hypoxic injury. J Fluoresc. 1995 Mar;5(1):71-84. doi: 10.1007/BF00718784. PMID: 24226613.
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8-pCPT-cGMP prevents mitochondrial depolarization and improves the outcome of steatotic partial liver transplantation.

International journal of physiology, pathophysiology and pharmacology

Liu Q, Rehman H, Krishnasamy Y, Lemasters JJ, Zhong Z.
PMID: 28694919
Int J Physiol Pathophysiol Pharmacol. 2017 Jun 15;9(3):69-83. eCollection 2017.

Permeant cGMP analogs prevent the mitochondria permeability transition (MPT)

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Liu Q, Rehman H, Krishnasamy Y, et al. 8-pCPT-cGMP prevents mitochondrial depolarization and improves the outcome of steatotic partial liver transplantation. Int J Physiol Pathophysiol Pharmacol. 2017;9(3):69-83
Liu, Q., Rehman, H., Krishnasamy, Y., Lemasters, J. J., & Zhong, Z. (2017). 8-pCPT-cGMP prevents mitochondrial depolarization and improves the outcome of steatotic partial liver transplantation. International journal of physiology, pathophysiology and pharmacology, 9(3), 69-83.
Liu, Qinlong, et al. "8-pCPT-cGMP prevents mitochondrial depolarization and improves the outcome of steatotic partial liver transplantation." International journal of physiology, pathophysiology and pharmacology vol. 9,3 (2017): 69-83.
Liu Q, Rehman H, Krishnasamy Y, Lemasters JJ, Zhong Z. 8-pCPT-cGMP prevents mitochondrial depolarization and improves the outcome of steatotic partial liver transplantation. Int J Physiol Pathophysiol Pharmacol. 2017 Jun 15;9(3):69-83. eCollection 2017. PMID: 28694919; PMCID: PMC5498880.
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Synthesis of Ultrasmall Synthetic Melanin Nanoparticles by UV Irradiation in Acidic and Neutral Conditions.

ACS applied bio materials

Lemaster JE, Jeevarathinam AS, Kumar A, Chandrasekar B, Chen F, Jokerst JV.
PMID: 31930189
ACS Appl Bio Mater. 2019 Oct 21;2(10):4667-4674. doi: 10.1021/acsabm.9b00747. Epub 2019 Sep 26.

Synthetic melanin nanoparticles have value in metal chelation, photoprotection, and biocompatibility. Applications of these materials have been reported in optics, biomedicine, and electronics. However, precise size control has remained relatively difficult-especially for materials below 1000 nm. In this paper...

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Lemaster JE, Jeevarathinam AS, Kumar A, et al. Synthesis of Ultrasmall Synthetic Melanin Nanoparticles by UV Irradiation in Acidic and Neutral Conditions. ACS Appl Bio Mater. 2019;2(10):4667-4674doi: 10.1021/acsabm.9b00747.
Lemaster, J. E., Jeevarathinam, A. S., Kumar, A., Chandrasekar, B., Chen, F., & Jokerst, J. V. (2019). Synthesis of Ultrasmall Synthetic Melanin Nanoparticles by UV Irradiation in Acidic and Neutral Conditions. ACS applied bio materials, 2(10), 4667-4674. https://doi.org/10.1021/acsabm.9b00747
Lemaster, Jeanne E, et al. "Synthesis of Ultrasmall Synthetic Melanin Nanoparticles by UV Irradiation in Acidic and Neutral Conditions." ACS applied bio materials vol. 2,10 (2019): 4667-4674. doi: https://doi.org/10.1021/acsabm.9b00747
Lemaster JE, Jeevarathinam AS, Kumar A, Chandrasekar B, Chen F, Jokerst JV. Synthesis of Ultrasmall Synthetic Melanin Nanoparticles by UV Irradiation in Acidic and Neutral Conditions. ACS Appl Bio Mater. 2019 Oct 21;2(10):4667-4674. doi: 10.1021/acsabm.9b00747. Epub 2019 Sep 26. PMID: 31930189; PMCID: PMC6953903.
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Role of mitochondrial depolarization and disrupted mitochondrial homeostasis in non-alcoholic steatohepatitis and fibrosis in mice.

International journal of physiology, pathophysiology and pharmacology

Krishnasamy Y, Gooz M, Li L, Lemasters JJ, Zhong Z.
PMID: 31777643
Int J Physiol Pathophysiol Pharmacol. 2019 Oct 15;11(5):190-204. eCollection 2019.

The pathogenesis of non-alcoholic steatohepatitis (NASH) is poorly understood. Here, relationships between mitochondrial depolarization (mtDepo) and mitochondrial homeostasis were studied in a mouse model of NASH. C57BL/6 mice were fed a Western diet (high fat, fructose and cholesterol) for...

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Krishnasamy Y, Gooz M, Li L, et al. Role of mitochondrial depolarization and disrupted mitochondrial homeostasis in non-alcoholic steatohepatitis and fibrosis in mice. Int J Physiol Pathophysiol Pharmacol. 2019;11(5):190-204
Krishnasamy, Y., Gooz, M., Li, L., Lemasters, J. J., & Zhong, Z. (2019). Role of mitochondrial depolarization and disrupted mitochondrial homeostasis in non-alcoholic steatohepatitis and fibrosis in mice. International journal of physiology, pathophysiology and pharmacology, 11(5), 190-204.
Krishnasamy, Yasodha, et al. "Role of mitochondrial depolarization and disrupted mitochondrial homeostasis in non-alcoholic steatohepatitis and fibrosis in mice." International journal of physiology, pathophysiology and pharmacology vol. 11,5 (2019): 190-204.
Krishnasamy Y, Gooz M, Li L, Lemasters JJ, Zhong Z. Role of mitochondrial depolarization and disrupted mitochondrial homeostasis in non-alcoholic steatohepatitis and fibrosis in mice. Int J Physiol Pathophysiol Pharmacol. 2019 Oct 15;11(5):190-204. eCollection 2019. PMID: 31777643; PMCID: PMC6872485.
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Protein triggered fluorescence switching of near-infrared emitting nanoparticles for contrast-enhanced imaging.

Journal of materials chemistry. B

Jetty R, Bandera YP, Daniele MA, Hanor D, Hung HI, Ramshesh V, Duperreault MF, Nieminen AL, Lemasters JJ, Foulger SH.
PMID: 32261197
J Mater Chem B. 2013 Sep 28;1(36):4542-4554. doi: 10.1039/c3tb20681e. Epub 2013 Jul 26.

Sub-100 nm colloidal particles which are surface-functionalized with multiple environmentally-sensitive moieties have the potential to combine imaging, early detection, and the treatment of cancer with a single type of long-circulating "nanodevice". Deep tissue imaging is achievable through the development...

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Jetty R, Bandera YP, Daniele MA, et al. Protein triggered fluorescence switching of near-infrared emitting nanoparticles for contrast-enhanced imaging. J Mater Chem B. 2013;1(36):4542-4554doi: 10.1039/c3tb20681e.
Jetty, R., Bandera, Y. P., Daniele, M. A., Hanor, D., Hung, H. I., Ramshesh, V., Duperreault, M. F., Nieminen, A. L., Lemasters, J. J., & Foulger, S. H. (2013). Protein triggered fluorescence switching of near-infrared emitting nanoparticles for contrast-enhanced imaging. Journal of materials chemistry. B, 1(36), 4542-4554. https://doi.org/10.1039/c3tb20681e
Jetty, Ragini, et al. "Protein triggered fluorescence switching of near-infrared emitting nanoparticles for contrast-enhanced imaging." Journal of materials chemistry. B vol. 1,36 (2013): 4542-4554. doi: https://doi.org/10.1039/c3tb20681e
Jetty R, Bandera YP, Daniele MA, Hanor D, Hung HI, Ramshesh V, Duperreault MF, Nieminen AL, Lemasters JJ, Foulger SH. Protein triggered fluorescence switching of near-infrared emitting nanoparticles for contrast-enhanced imaging. J Mater Chem B. 2013 Sep 28;1(36):4542-4554. doi: 10.1039/c3tb20681e. Epub 2013 Jul 26. PMID: 32261197.
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Ischemic preconditioning of rat livers from non-heart-beating donors decreases parenchymal cell killing and increases graft survival after transplantation.

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery

Currin RT, Peng XX, Lemasters JJ.
PMID: 22888183
HPB Surg. 2012;2012:236406. doi: 10.1155/2012/236406. Epub 2012 Jul 19.

A critical shortage of donors exists for liver transplantation, which non-heart-beating cadaver donors could help ease. This study evaluated ischemic preconditioning to improve graft viability after non-heart-beating liver donation in rats. Ischemic preconditioning was performed by clamping the portal...

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Currin RT, Peng XX, Lemasters JJ. Ischemic preconditioning of rat livers from non-heart-beating donors decreases parenchymal cell killing and increases graft survival after transplantation. HPB Surg. 2012;2012:236406doi: 10.1155/2012/236406.
Currin, R. T., Peng, X. X., & Lemasters, J. J. (2012). Ischemic preconditioning of rat livers from non-heart-beating donors decreases parenchymal cell killing and increases graft survival after transplantation. HPB surgery : a world journal of hepatic, pancreatic and biliary surgery, 2012236406. https://doi.org/10.1155/2012/236406
Currin, Robert T, et al. "Ischemic preconditioning of rat livers from non-heart-beating donors decreases parenchymal cell killing and increases graft survival after transplantation." HPB surgery : a world journal of hepatic, pancreatic and biliary surgery vol. 2012 (2012): 236406. doi: https://doi.org/10.1155/2012/236406
Currin RT, Peng XX, Lemasters JJ. Ischemic preconditioning of rat livers from non-heart-beating donors decreases parenchymal cell killing and increases graft survival after transplantation. HPB Surg. 2012;2012:236406. doi: 10.1155/2012/236406. Epub 2012 Jul 19. PMID: 22888183; PMCID: PMC3408666.
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Development of a Trimodal Contrast Agent for Acoustic and Magnetic Particle Imaging of Stem Cells.

ACS applied nano materials

Lemaster JE, Chen F, Kim T, Hariri A, Jokerst JV.
PMID: 33860154
ACS Appl Nano Mater. 2018 Mar 23;1(3):1321-1331. doi: 10.1021/acsanm.8b00063. Epub 2018 Mar 02.

Stem cell therapy has the potential to improve tissue remodeling and repair. For cardiac stem cell therapy, methods to improve the injection and tracking of stem cells may help to increase patient outcomes. Here we describe a multimodal approach...

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Lemaster JE, Chen F, Kim T, et al. Development of a Trimodal Contrast Agent for Acoustic and Magnetic Particle Imaging of Stem Cells. ACS Appl Nano Mater. 2018;1(3):1321-1331doi: 10.1021/acsanm.8b00063.
Lemaster, J. E., Chen, F., Kim, T., Hariri, A., & Jokerst, J. V. (2018). Development of a Trimodal Contrast Agent for Acoustic and Magnetic Particle Imaging of Stem Cells. ACS applied nano materials, 1(3), 1321-1331. https://doi.org/10.1021/acsanm.8b00063
Lemaster, Jeanne E, et al. "Development of a Trimodal Contrast Agent for Acoustic and Magnetic Particle Imaging of Stem Cells." ACS applied nano materials vol. 1,3 (2018): 1321-1331. doi: https://doi.org/10.1021/acsanm.8b00063
Lemaster JE, Chen F, Kim T, Hariri A, Jokerst JV. Development of a Trimodal Contrast Agent for Acoustic and Magnetic Particle Imaging of Stem Cells. ACS Appl Nano Mater. 2018 Mar 23;1(3):1321-1331. doi: 10.1021/acsanm.8b00063. Epub 2018 Mar 02. PMID: 33860154; PMCID: PMC8046030.
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Economic Burden of Asthma-Chronic Obstructive Pulmonary Disease Overlap among Older Adults in the United States.

COPD

Nili M, Dwibedi N, Adelman M, LeMasters T, Madhavan SS, Sambamoorthi U.
PMID: 33902371
COPD. 2021 Jun;18(3):357-366. doi: 10.1080/15412555.2021.1909549. Epub 2021 Apr 26.

The objective of this study is to estimate the excess economic burden of Asthma-COPD Overlap (ACO) among older adults in the United States. We used a cross-sectional study design with data from a nationally representative survey of Medicare beneficiaries...

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Nili M, Dwibedi N, Adelman M, et al. Economic Burden of Asthma-Chronic Obstructive Pulmonary Disease Overlap among Older Adults in the United States. COPD. 2021;18(3):357-366doi: 10.1080/15412555.2021.1909549.
Nili, M., Dwibedi, N., Adelman, M., LeMasters, T., Madhavan, S. S., & Sambamoorthi, U. (2021). Economic Burden of Asthma-Chronic Obstructive Pulmonary Disease Overlap among Older Adults in the United States. COPD, 18(3), 357-366. https://doi.org/10.1080/15412555.2021.1909549
Nili, Mona, et al. "Economic Burden of Asthma-Chronic Obstructive Pulmonary Disease Overlap among Older Adults in the United States." COPD vol. 18,3 (2021): 357-366. doi: https://doi.org/10.1080/15412555.2021.1909549
Nili M, Dwibedi N, Adelman M, LeMasters T, Madhavan SS, Sambamoorthi U. Economic Burden of Asthma-Chronic Obstructive Pulmonary Disease Overlap among Older Adults in the United States. COPD. 2021 Jun;18(3):357-366. doi: 10.1080/15412555.2021.1909549. Epub 2021 Apr 26. PMID: 33902371.
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Quantitative and semiquantitative estimates of mold exposure in infancy and childhood respiratory health.

Environmental epidemiology (Philadelphia, Pa.)

Cox J, Ryan P, Burkle J, Jandarov R, Mendell MJ, Hershey GK, LeMasters G, Reponen T.
PMID: 32832840
Environ Epidemiol. 2020 Jun 19;4(4):e101. doi: 10.1097/EE9.0000000000000101. eCollection 2020 Aug.

BACKGROUND: Previous epidemiologic studies of dampness and mold relied on metrics that did not fully assess exposure-response relationships. Our objective was to examine quantitative metrics of dampness and mold during infancy and respiratory health outcomes during childhood.METHODS: In-home visits...

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Cox J, Ryan P, Burkle J, et al. Quantitative and semiquantitative estimates of mold exposure in infancy and childhood respiratory health. Environ Epidemiol. 2020;4(4):e101doi: 10.1097/EE9.0000000000000101.
Cox, J., Ryan, P., Burkle, J., Jandarov, R., Mendell, M. J., Hershey, G. K., LeMasters, G., & Reponen, T. (2020). Quantitative and semiquantitative estimates of mold exposure in infancy and childhood respiratory health. Environmental epidemiology (Philadelphia, Pa.), 4(4), e101. https://doi.org/10.1097/EE9.0000000000000101
Cox, Jennie, et al. "Quantitative and semiquantitative estimates of mold exposure in infancy and childhood respiratory health." Environmental epidemiology (Philadelphia, Pa.) vol. 4,4 (2020): e101. doi: https://doi.org/10.1097/EE9.0000000000000101
Cox J, Ryan P, Burkle J, Jandarov R, Mendell MJ, Hershey GK, LeMasters G, Reponen T. Quantitative and semiquantitative estimates of mold exposure in infancy and childhood respiratory health. Environ Epidemiol. 2020 Jun 19;4(4):e101. doi: 10.1097/EE9.0000000000000101. eCollection 2020 Aug. PMID: 32832840; PMCID: PMC7423528.
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Ischemic preconditioning attenuates acute lung injury after partial liver transplantation.

International journal of physiology, pathophysiology and pharmacology

Liu Q, Rehman H, Krishnasamy Y, Lemasters JJ, Zhong Z.
PMID: 29755641
Int J Physiol Pathophysiol Pharmacol. 2018 Apr 20;10(2):83-94. eCollection 2018.

Pulmonary complications frequently occur after liver transplantation and are often life-threatening. Thus, we investigated whether hepatic ischemic preconditioning (IP) attenuates acute lung injury (ALI) after small-for-size liver transplantation. Rat livers were explanted after 9-min ischemia plus 5-min reperfusion, reduced...

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Liu Q, Rehman H, Krishnasamy Y, et al. Ischemic preconditioning attenuates acute lung injury after partial liver transplantation. Int J Physiol Pathophysiol Pharmacol. 2018;10(2):83-94
Liu, Q., Rehman, H., Krishnasamy, Y., Lemasters, J. J., & Zhong, Z. (2018). Ischemic preconditioning attenuates acute lung injury after partial liver transplantation. International journal of physiology, pathophysiology and pharmacology, 10(2), 83-94.
Liu, Qinlong, et al. "Ischemic preconditioning attenuates acute lung injury after partial liver transplantation." International journal of physiology, pathophysiology and pharmacology vol. 10,2 (2018): 83-94.
Liu Q, Rehman H, Krishnasamy Y, Lemasters JJ, Zhong Z. Ischemic preconditioning attenuates acute lung injury after partial liver transplantation. Int J Physiol Pathophysiol Pharmacol. 2018 Apr 20;10(2):83-94. eCollection 2018. PMID: 29755641; PMCID: PMC5943607.
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Parental Snoring and Environmental Pollutants, but Not Aeroallergen Sensitization, Are Associated with Childhood Snoring in a Birth Cohort.

Pediatric allergy, immunology, and pulmonology

Kannan JA, Brokamp C, Bernstein DI, LeMasters GK, Hershey GKK, Villareal MS, Lockey JE, Ryan PH.
PMID: 28465864
Pediatr Allergy Immunol Pulmonol. 2017 Mar 01;30(1):31-38. doi: 10.1089/ped.2016.0681.

The objective of this study was to determine whether atopy and other clinical and environmental variables predict the risk of childhood habitual snoring (HS) in a birth cohort born to atopic parents. Participants completed clinical evaluations and questionnaires at...

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Kannan JA, Brokamp C, Bernstein DI, et al. Parental Snoring and Environmental Pollutants, but Not Aeroallergen Sensitization, Are Associated with Childhood Snoring in a Birth Cohort. Pediatr Allergy Immunol Pulmonol. 2017;30(1):31-38doi: 10.1089/ped.2016.0681.
Kannan, J. A., Brokamp, C., Bernstein, D. I., LeMasters, G. K., Hershey, G. K. K., Villareal, M. S., Lockey, J. E., & Ryan, P. H. (2017). Parental Snoring and Environmental Pollutants, but Not Aeroallergen Sensitization, Are Associated with Childhood Snoring in a Birth Cohort. Pediatric allergy, immunology, and pulmonology, 30(1), 31-38. https://doi.org/10.1089/ped.2016.0681
Kannan, Jennifer A, et al. "Parental Snoring and Environmental Pollutants, but Not Aeroallergen Sensitization, Are Associated with Childhood Snoring in a Birth Cohort." Pediatric allergy, immunology, and pulmonology vol. 30,1 (2017): 31-38. doi: https://doi.org/10.1089/ped.2016.0681
Kannan JA, Brokamp C, Bernstein DI, LeMasters GK, Hershey GKK, Villareal MS, Lockey JE, Ryan PH. Parental Snoring and Environmental Pollutants, but Not Aeroallergen Sensitization, Are Associated with Childhood Snoring in a Birth Cohort. Pediatr Allergy Immunol Pulmonol. 2017 Mar 01;30(1):31-38. doi: 10.1089/ped.2016.0681. PMID: 28465864; PMCID: PMC5361763.
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Showing 1 to 12 of 54 entries