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Showing 1 to 12 of 18 entries
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A molecular risk score integrating BAALC, ERG and WT1 expression levels for risk stratification in acute promyelocytic leukemia.

Leukemia research

Hecht A, Nowak D, Nowak V, Hanfstein B, Büchner T, Spiekermann K, Weiß C, Hofmann WK, Lengfelder E, Nolte F.
PMID: 26344466
Leuk Res. 2015 Aug 20; doi: 10.1016/j.leukres.2015.08.010. Epub 2015 Aug 20.

To date risk stratification in acute promyelocytic leukemia (APL) is based on highly dynamic leukocyte and platelet counts only. To identify a more robust risk stratification model, a molecular risk score was developed based on expression levels of the...

Natural and Chernobyl-caused radioactivity in mushrooms, mosses and soil-samples of defined biotops in SW Bavaria.

Oecologia

Elstner EF, Fink R, Höll W, Lengfelder E, Ziegler H.
PMID: 28311973
Oecologia. 1987 Oct;73(4):553-558. doi: 10.1007/BF00379415.

Different mushrooms, mosses and corresponding soil samples have been collected mainly from two sites in the alpine region of southwestern Bavaria. At the end of the growthseason, September 1986, gamma spectroscopic analysis showed that the moss-, mould, and needle-layer...

Prevalence and impact of malnutrition on length of stay, readmission, and discharge destination.

JPEN. Journal of parenteral and enteral nutrition

Lengfelder L, Mahlke S, Moore L, Zhang X, Williams G, Lee J.
PMID: 34967019
JPEN J Parenter Enteral Nutr. 2021 Dec 29; doi: 10.1002/jpen.2322. Epub 2021 Dec 29.

BACKGROUND: Studies indicate one in three hospitalized patients are malnourished upon admission, however, the documented malnutrition rate in acute care hospitals is often lower. This study measured prevalence of malnutrition upon admission and correlated the relationship among malnutrition status,...

Publisher Correction: Outcome of older (≥70 years) APL patients frontline treated with or without arsenic trioxide-an International Collaborative Study.

Leukemia

Kayser S, Rahmé R, Martínez-Cuadrón D, Ghiaur G, Thomas X, Sobas M, Guerci-Bresler A, Garrido A, Pigneux A, Gil C, Raffoux E, Tormo M, Vey N, de la Serna J, Salamero O, Lengfelder E, Levis MJ, Fenaux P, Sanz MA, Platzbecker U, Schlenk RF, Adès L, Montesinos P.
PMID: 34785795
Leukemia. 2021 Dec;35(12):3631. doi: 10.1038/s41375-021-01358-3.

No abstract available.

Fast R Functions for Robust Correlations and Hierarchical Clustering.

Journal of statistical software

Langfelder P, Horvath S.
PMID: 23050260
J Stat Softw. 2012 Mar;46(11).

Many high-throughput biological data analyses require the calculation of large correlation matrices and/or clustering of a large number of objects. The standard R function for calculating Pearson correlation can handle calculations without missing values efficiently, but is inefficient when...

Characteristics and outcome of patients with low-/intermediate-risk acute promyelocytic leukemia treated with arsenic trioxide: an international collaborative study.

Haematologica

Kayser S, Schlenk RF, Lebon D, Carre M, Götze KS, Stölzel F, Berceanu A, Schäfer-Eckart K, Peterlin P, Hicheri Y, Rahme R, Raffoux E, Chermat F, Krause SW, Aulitzky WE, Rigaudeau S, Noppeney R, Berthon C, Görner M, Jost E, Carassou P, Keller U, Orvain C, Braun T, Saillard C, Arar A, Kunzmann V, Wemeau M, De Wit M, Niemann D, Bonmati C, Schwänen C, Abraham J, Aljijakli A, Haiat S, Krämer A, Reichle A, Gnadler M, Willekens C, Spiekermann K, Hiddemann W, Müller-Tidow C, Thiede C, Röllig C, Serve H, Bornhäuser M, Baldus CD, Lengfelder E, Fenaux P, Platzbecker U, Adès L.
PMID: 34047178
Haematologica. 2021 Dec 01;106(12):3100-3106. doi: 10.3324/haematol.2021.278722.

The aim of this study was to characterize a large series of 154 patients with acute promyelocytic leukemia (median age, 53 years; range, 18-90 years) and evaluate real-life outcome after up-front treatment with arsenic trioxide and all-trans retinoic acid....

Characteristics and outcome of patients with low-/intermediate-risk acute promyelocytic leukemia treated with arsenic trioxide: an international collaborative study.

Haematologica

Kayser S, Schlenk RF, Lebon D, Carre M, Götze KS, Stölzel F, Berceanu A, Schäfer-Eckart K, Peterlin P, Hicheri Y, Rahme R, Raffoux E, Chermat F, Krause SW, Aulitzky WE, Rigaudeau S, Noppeney R, Berthon C, Görner M, Jost E, Carassou P, Keller U, Orvain C, Braun T, Saillard C, Arar A, Kunzmann V, Wemeau M, De Wit M, Niemann D, Bonmati C, Schwänen C, Abraham J, Aljijakli A, Haiat S, Krämer A, Reichle A, Gnadler M, Willekens C, Spiekermann K, Hiddemann W, Müller-Tidow C, Thiede C, Röllig C, Serve H, Bornhäuser M, Baldus CD, Lengfelder E, Fenaux P, Platzbecker U, Adès L.
PMID: 34047178
Haematologica. 2021 Dec 01;106(12):3100-3106. doi: 10.3324/haematol.2021.278722.

The aim of this study was to characterize a large series of 154 patients with acute promyelocytic leukemia (median age, 53 years; range, 18-90 years) and evaluate real-life outcome after up-front treatment with arsenic trioxide and all-trans retinoic acid....

Core liver homeostatic co-expression networks are preserved but respond to perturbations in an organism- and disease-specific manner.

Cell systems

Esmaili S, Langfelder P, Belgard TG, Vitale D, Azardaryany MK, Alipour Talesh G, Ramezani-Moghadam M, Ho V, Dvorkin D, Dervish S, Gloss BS, Grønbæk H, Liddle C, George J.
PMID: 33957084
Cell Syst. 2021 May 19;12(5):432-445.e7. doi: 10.1016/j.cels.2021.04.004. Epub 2021 May 05.

Findings about chronic complex diseases are difficult to extrapolate from animal models to humans. We reason that organs may have core network modules that are preserved between species and are predictably altered when homeostasis is disrupted. To test this...

Publisher Correction: Outcome of older (≥70 years) APL patients frontline treated with or without arsenic trioxide-an International Collaborative Study.

Leukemia

Kayser S, Rahmé R, Martínez-Cuadrón D, Ghiaur G, Thomas X, Sobas M, Guerci-Bresler A, Garrido A, Pigneux A, Gil C, Raffoux E, Tormo M, Vey N, de la Serna J, Salamero O, Lengfelder E, Levis MJ, Fenaux P, Sanz MA, Platzbecker U, Schlenk RF, Adès L, Montesinos P.
PMID: 34785795
Leukemia. 2021 Dec;35(12):3631. doi: 10.1038/s41375-021-01358-3.

No abstract available.

Exosomes and Homeostatic Synaptic Plasticity Are Linked to Each other and to Huntington's, Parkinson's, and Other Neurodegenerative Diseases by Database-Enabled Analyses of Comprehensively Curated Datasets.

Frontiers in neuroscience

Wang JKT, Langfelder P, Horvath S, Palazzolo MJ.
PMID: 28611571
Front Neurosci. 2017 Mar 31;11:149. doi: 10.3389/fnins.2017.00149. eCollection 2017.

Huntington's disease (HD) is a progressive and autosomal dominant neurodegeneration caused by CAG expansion in the huntingtin gene (

[Diagnosis and treatment of polycythemia vera in the year 2015].

Deutsche medizinische Wochenschrift (1946)

Lengfelder E, Griesshammer M, Koschmieder S.
PMID: 26636622
Dtsch Med Wochenschr. 2015 Oct;140(20):e256. doi: 10.1055/s-0041-110562. Epub 2015 Dec 04.

No abstract available.

Radioactivity in mushrooms, mosses and soil samples of defined biotops in SW Bavaria-two years after "Chernobyl".

Oecologia

Elstner EF, Fink R, Höll W, Lengfelder E, Ziegler H.
PMID: 28313103
Oecologia. 1989 Aug;80(2):173-177. doi: 10.1007/BF00380147.

Mushrooms, the moos/grass layer and soil samples have been collected in autumn 1987 from two sites in SW-Bavaria in continuation of a former investigation (Elstner et al. 1987). There were still relatively high amounts of

Showing 1 to 12 of 18 entries