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Showing 1 to 12 of 13 entries
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How the Chemical Properties of GBCAs Influence Their Safety Profiles In Vivo.

Molecules (Basel, Switzerland)

Do QN, Lenkinski RE, Tircso G, Kovacs Z.
PMID: 35011290
Molecules. 2021 Dec 23;27(1). doi: 10.3390/molecules27010058.

The extracellular class of gadolinium-based contrast agents (GBCAs) is an essential tool for clinical diagnosis and disease management. In order to better understand the issues associated with GBCA administration and gadolinium retention and deposition in the human brain, the...

Improving the Accuracy of Screening Dense Breasted Women for Breast Cancer By Combining Clinically Based Risk Assessment Models with Ultrasound Imaging.

Academic radiology

Lenkinski RE.
PMID: 34702674
Acad Radiol. 2021 Oct 23; doi: 10.1016/j.acra.2021.09.019. Epub 2021 Oct 23.

No abstract available.

Addressing metabolic heterogeneity in clear cell renal cell carcinoma with quantitative Dixon MRI.

JCI insight

Zhang Y, Udayakumar D, Cai L, Hu Z, Kapur P, Kho EY, Pavía-Jiménez A, Fulkerson M, de Leon AD, Yuan Q, Dimitrov IE, Yokoo T, Ye J, Mitsche MA, Kim H, McDonald JG, Xi Y, Madhuranthakam AJ, Dwivedi DK, Lenkinski RE, Cadeddu JA, Margulis V, Brugarolas J, DeBerardinis RJ, Pedrosa I.
PMID: 28768909
JCI Insight. 2017 Aug 03;2(15). doi: 10.1172/jci.insight.94278. eCollection 2017 Aug 03.

BACKGROUND: Dysregulated lipid and glucose metabolism in clear cell renal cell carcinoma (ccRCC) has been implicated in disease progression, and whole tumor tissue-based assessment of these changes is challenged by the tumor heterogeneity. We studied a noninvasive quantitative MRI...

Integrating Structural and Functional Imaging for Computer Assisted Detection of Prostate Cancer on Multi-Protocol .

Proceedings of SPIE--the International Society for Optical Engineering

Viswanath S, Bloch BN, Rosen M, Chappelow J, Toth R, Rofsky N, Lenkinski R, Genega E, Kalyanpur A, Madabhushi A.
PMID: 25301989
Proc SPIE Int Soc Opt Eng. 2009 Feb 27;7260:72603I. doi: 10.1117/12.811899.

Screening and detection of prostate cancer (CaP) currently lacks an image-based protocol which is reflected in the high false negative rates currently associated with blinded sextant biopsies. Multi-protocol magnetic resonance imaging (MRI) offers high resolution functional and structural data...

How the Chemical Properties of GBCAs Influence Their Safety Profiles In Vivo.

Molecules (Basel, Switzerland)

Do QN, Lenkinski RE, Tircso G, Kovacs Z.
PMID: 35011290
Molecules. 2021 Dec 23;27(1). doi: 10.3390/molecules27010058.

The extracellular class of gadolinium-based contrast agents (GBCAs) is an essential tool for clinical diagnosis and disease management. In order to better understand the issues associated with GBCA administration and gadolinium retention and deposition in the human brain, the...

The use of T2 distribution to study tumor extent and heterogeneity in head and neck cancer.

Magnetic resonance imaging

Bloch P, Lenkinski RE, Buhle EL, Hendrix R, Bryer M, McKenna WG.
PMID: 2034054
Magn Reson Imaging. 1991;9(2):205-11. doi: 10.1016/0730-725x(91)90012-b.

Demarcation of the extent of malignant tissue is essential for planning a course of radiotherapy. MR images may provide additional information for delineating the target volume because of the large difference in the proton magnetic resonance relaxation times between...

MR spectroscopy: Clinical tool or research probe? (revisited).

Academic radiology

Lenkinski RE.
PMID: 11450956
Acad Radiol. 2001 Jul;8(7):567-70. doi: 10.1016/S1076-6332(03)80680-3.

No abstract available.

Personal diary: a research PhD's perspective.

Academic radiology

Lenkinski RE.
PMID: 11227646
Acad Radiol. 2001 Feb;8(2):173-4. doi: 10.1016/s1076-6332(01)90152-7.

No abstract available.

MR Neurography: Advances.

Radiology research and practice

Chhabra A, Zhao L, Carrino JA, Trueblood E, Koceski S, Shteriev F, Lenkinski L, Sinclair CD, Andreisek G.
PMID: 23589774
Radiol Res Pract. 2013;2013:809568. doi: 10.1155/2013/809568. Epub 2013 Mar 26.

High resolution and high field magnetic resonance neurography (MR neurography, MRN) is shown to have excellent anatomic capability. There have been considerable advances in the technology in the last few years leading to various feasibility studies using different structural...

Enhanced Multi-Protocol Analysis via Intelligent Supervised Embedding (EMPrAvISE): Detecting Prostate Cancer on Multi-Parametric MRI.

Proceedings of SPIE--the International Society for Optical Engineering

Viswanath S, Bloch BN, Chappelow J, Patel P, Rofsky N, Lenkinski R, Genega E, Madabhushi A.
PMID: 25301991
Proc SPIE Int Soc Opt Eng. 2011 Mar 04;7963:79630U. doi: 10.1117/12.878312.

Currently, there is significant interest in developing methods for quantitative integration of multi-parametric (structural, functional) imaging data with the objective of building automated meta-classifiers to improve disease detection, diagnosis, and prognosis. Such techniques are required to address the differences...

Statistical 3D Prostate Imaging Atlas Construction via Anatomically Constrained Registration.

Proceedings of SPIE--the International Society for Optical Engineering

Rusu M, Bloch BN, Jaffe CC, Rofsky NM, Genega EM, Feleppa E, Lenkinski RE, Madabhushi A.
PMID: 24392203
Proc SPIE Int Soc Opt Eng. 2013 Mar 13;8669. doi: 10.1117/12.2006941.

Statistical imaging atlases allow for integration of information from multiple patient studies collected across different image scales and modalities, such as multi-parametric (MP) MRI and histology, providing population statistics regarding a specific pathology within a single canonical representation. Such...

Low-to-high b value DWI ratio approaches in multiparametric MRI of the prostate: feasibility, optimal combination of b values, and comparison with ADC maps for the visual presentation of prostate cancer.

Quantitative imaging in medicine and surgery

Xi Y, Liu A, Olumba F, Lawson P, Costa DN, Yuan Q, Khatri G, Yokoo T, Pedrosa I, Lenkinski RE.
PMID: 30140618
Quant Imaging Med Surg. 2018 Jul;8(6):557-567. doi: 10.21037/qims.2018.06.08.

BACKGROUND: Diffusion-weighted imaging (DWI) is considered by experts as one of the key elements in multi-parametric magnetic resonance imaging (mpMRI) employed in oncological studies outside the brain. A low-to-high b value ratio DWI has been proposed as an approach...

Showing 1 to 12 of 13 entries