Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 6 of 6 entries
Sorted by: Best Match Show Resources per page
Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon.

Molecular therapy. Nucleic acids

Broos K, Van der Jeught K, Puttemans J, Goyvaerts C, Heirman C, Dewitte H, Verbeke R, Lentacker I, Thielemans K, Breckpot K.
PMID: 27327138
Mol Ther Nucleic Acids. 2016 Jun 21;5(6):e326. doi: 10.1038/mtna.2016.38.

Cancer vaccines based on mRNA are extensively studied. The fragile nature of mRNA has instigated research into carriers that can protect it from ribonucleases and as such enable its systemic use. However, carrier-mediated delivery of mRNA has been linked...

Cite
Broos K, Van der Jeught K, Puttemans J, et al. Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon. Mol Ther Nucleic Acids. 2016;5(6):e326doi: 10.1038/mtna.2016.38.
Broos, K., Van der Jeught, K., Puttemans, J., Goyvaerts, C., Heirman, C., Dewitte, H., Verbeke, R., Lentacker, I., Thielemans, K., & Breckpot, K. (2016). Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon. Molecular therapy. Nucleic acids, 5(6), e326. https://doi.org/10.1038/mtna.2016.38
Broos, Katrijn, et al. "Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon." Molecular therapy. Nucleic acids vol. 5,6 (2016): e326. doi: https://doi.org/10.1038/mtna.2016.38
Broos K, Van der Jeught K, Puttemans J, Goyvaerts C, Heirman C, Dewitte H, Verbeke R, Lentacker I, Thielemans K, Breckpot K. Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon. Mol Ther Nucleic Acids. 2016 Jun 21;5(6):e326. doi: 10.1038/mtna.2016.38. PMID: 27327138; PMCID: PMC5022130.
Copy Download .nbib Format: NLM
Longitudinal In Vivo Assessment of Host-Microbe Interactions in a Murine Model of Pulmonary Aspergillosis.

iScience

Saini S, Poelmans J, Korf H, Dooley JL, Liang S, Manshian BB, Verbeke R, Soenen SJ, Vande Velde G, Lentacker I, Lagrou K, Liston A, Gysemans C, De Smedt SC, Himmelreich U.
PMID: 31581067
iScience. 2019 Oct 25;20:184-194. doi: 10.1016/j.isci.2019.09.022. Epub 2019 Sep 18.

The fungus Aspergillus fumigatus is ubiquitous in nature and the most common cause of invasive pulmonary aspergillosis (IPA) in patients with a compromised immune system. The development of IPA in patients under immunosuppressive treatment or in patients with primary...

Cite
Saini S, Poelmans J, Korf H, et al. Longitudinal In Vivo Assessment of Host-Microbe Interactions in a Murine Model of Pulmonary Aspergillosis. iScience. 2019;20:184-194doi: 10.1016/j.isci.2019.09.022.
Saini, S., Poelmans, J., Korf, H., Dooley, J. L., Liang, S., Manshian, B. B., Verbeke, R., Soenen, S. J., Vande Velde, G., Lentacker, I., Lagrou, K., Liston, A., Gysemans, C., De Smedt, S. C., & Himmelreich, U. (2019). Longitudinal In Vivo Assessment of Host-Microbe Interactions in a Murine Model of Pulmonary Aspergillosis. iScience, 20184-194. https://doi.org/10.1016/j.isci.2019.09.022
Saini, Shweta, et al. "Longitudinal In Vivo Assessment of Host-Microbe Interactions in a Murine Model of Pulmonary Aspergillosis." iScience vol. 20 (2019): 184-194. doi: https://doi.org/10.1016/j.isci.2019.09.022
Saini S, Poelmans J, Korf H, Dooley JL, Liang S, Manshian BB, Verbeke R, Soenen SJ, Vande Velde G, Lentacker I, Lagrou K, Liston A, Gysemans C, De Smedt SC, Himmelreich U. Longitudinal In Vivo Assessment of Host-Microbe Interactions in a Murine Model of Pulmonary Aspergillosis. iScience. 2019 Oct 25;20:184-194. doi: 10.1016/j.isci.2019.09.022. Epub 2019 Sep 18. PMID: 31581067; PMCID: PMC6817634.
Copy Download .nbib Format: NLM
mRNA Encoding a Bispecific Single Domain Antibody Construct Protects against Influenza A Virus Infection in Mice.

Molecular therapy. Nucleic acids

Van Hoecke L, Verbeke R, De Vlieger D, Dewitte H, Roose K, Van Nevel S, Krysko O, Bachert C, Schepens B, Lentacker I, Saelens X.
PMID: 32438313
Mol Ther Nucleic Acids. 2020 Jun 05;20:777-787. doi: 10.1016/j.omtn.2020.04.015. Epub 2020 May 01.

To date, mRNA-based biologics have mainly been developed for prophylactic and therapeutic vaccination to combat infectious diseases or cancer. In the past years, optimization of the characteristics of in vitro transcribed mRNA has led to significant reduction of the...

Cite
Van Hoecke L, Verbeke R, De Vlieger D, et al. mRNA Encoding a Bispecific Single Domain Antibody Construct Protects against Influenza A Virus Infection in Mice. Mol Ther Nucleic Acids. 2020;20:777-787doi: 10.1016/j.omtn.2020.04.015.
Van Hoecke, L., Verbeke, R., De Vlieger, D., Dewitte, H., Roose, K., Van Nevel, S., Krysko, O., Bachert, C., Schepens, B., Lentacker, I., & Saelens, X. (2020). mRNA Encoding a Bispecific Single Domain Antibody Construct Protects against Influenza A Virus Infection in Mice. Molecular therapy. Nucleic acids, 20777-787. https://doi.org/10.1016/j.omtn.2020.04.015
Van Hoecke, Lien, et al. "mRNA Encoding a Bispecific Single Domain Antibody Construct Protects against Influenza A Virus Infection in Mice." Molecular therapy. Nucleic acids vol. 20 (2020): 777-787. doi: https://doi.org/10.1016/j.omtn.2020.04.015
Van Hoecke L, Verbeke R, De Vlieger D, Dewitte H, Roose K, Van Nevel S, Krysko O, Bachert C, Schepens B, Lentacker I, Saelens X. mRNA Encoding a Bispecific Single Domain Antibody Construct Protects against Influenza A Virus Infection in Mice. Mol Ther Nucleic Acids. 2020 Jun 05;20:777-787. doi: 10.1016/j.omtn.2020.04.015. Epub 2020 May 01. PMID: 32438313; PMCID: PMC7240188.
Copy Download .nbib Format: NLM
Focal Delivery of AAV2/1-transgenes Into the Rat Brain by Localized Ultrasound-induced BBB Opening.

Molecular therapy. Nucleic acids

Alonso A, Reinz E, Leuchs B, Kleinschmidt J, Fatar M, Geers B, Lentacker I, Hennerici MG, de Smedt SC, Meairs S.
PMID: 23423361
Mol Ther Nucleic Acids. 2013 Feb 19;2:e73. doi: 10.1038/mtna.2012.64.

Delivery of drugs and macromolecules to the central nervous system (CNS) is hindered by the blood-brain barrier (BBB). Several approaches have been used to overcome this hindrance to facilitate the treatment of various CNS diseases. We now present results...

Cite
Alonso A, Reinz E, Leuchs B, et al. Focal Delivery of AAV2/1-transgenes Into the Rat Brain by Localized Ultrasound-induced BBB Opening. Mol Ther Nucleic Acids. 2013;2:e73doi: 10.1038/mtna.2012.64.
Alonso, A., Reinz, E., Leuchs, B., Kleinschmidt, J., Fatar, M., Geers, B., Lentacker, I., Hennerici, M. G., de Smedt, S. C., & Meairs, S. (2013). Focal Delivery of AAV2/1-transgenes Into the Rat Brain by Localized Ultrasound-induced BBB Opening. Molecular therapy. Nucleic acids, 2e73. https://doi.org/10.1038/mtna.2012.64
Alonso, Angelika, et al. "Focal Delivery of AAV2/1-transgenes Into the Rat Brain by Localized Ultrasound-induced BBB Opening." Molecular therapy. Nucleic acids vol. 2 (2013): e73. doi: https://doi.org/10.1038/mtna.2012.64
Alonso A, Reinz E, Leuchs B, Kleinschmidt J, Fatar M, Geers B, Lentacker I, Hennerici MG, de Smedt SC, Meairs S. Focal Delivery of AAV2/1-transgenes Into the Rat Brain by Localized Ultrasound-induced BBB Opening. Mol Ther Nucleic Acids. 2013 Feb 19;2:e73. doi: 10.1038/mtna.2012.64. PMID: 23423361; PMCID: PMC3586801.
Copy Download .nbib Format: NLM
Focal delivery of AAV2/1-transgenes into the rat brain by localized ultrasound-induced BBB Opening.

Annals of neurosciences

Alonso A, Reinz E, Leuchs B, Kleinschmidt J, Fatar M, Geers B, Lentacker I, Hennerici MG, de Smedt SC, Meairs S.
PMID: 25206050
Ann Neurosci. 2014 Jan;21(1):22. doi: 10.5214/ans.0972.7531.210107.

No abstract available.

Cite
Alonso A, Reinz E, Leuchs B, et al. Focal delivery of AAV2/1-transgenes into the rat brain by localized ultrasound-induced BBB Opening. Ann Neurosci. 2014;21(1):22doi: 10.5214/ans.0972.7531.210107.
Alonso, A., Reinz, E., Leuchs, B., Kleinschmidt, J., Fatar, M., Geers, B., Lentacker, I., Hennerici, M. G., de Smedt, S. C., & Meairs, S. (2014). Focal delivery of AAV2/1-transgenes into the rat brain by localized ultrasound-induced BBB Opening. Annals of neurosciences, 21(1), 22. https://doi.org/10.5214/ans.0972.7531.210107
Alonso, Angelika, et al. "Focal delivery of AAV2/1-transgenes into the rat brain by localized ultrasound-induced BBB Opening." Annals of neurosciences vol. 21,1 (2014): 22. doi: https://doi.org/10.5214/ans.0972.7531.210107
Alonso A, Reinz E, Leuchs B, Kleinschmidt J, Fatar M, Geers B, Lentacker I, Hennerici MG, de Smedt SC, Meairs S. Focal delivery of AAV2/1-transgenes into the rat brain by localized ultrasound-induced BBB Opening. Ann Neurosci. 2014 Jan;21(1):22. doi: 10.5214/ans.0972.7531.210107. PMID: 25206050; PMCID: PMC4117153.
Copy Download .nbib Format: NLM
In vitro methods to study bubble-cell interactions: Fundamentals and therapeutic applications.

Biomicrofluidics

Lajoinie G, De Cock I, Coussios CC, Lentacker I, Le Gac S, Stride E, Versluis M.
PMID: 26865903
Biomicrofluidics. 2016 Jan 28;10(1):011501. doi: 10.1063/1.4940429. eCollection 2016 Jan.

Besides their use as contrast agents for ultrasound imaging, microbubbles are increasingly studied for a wide range of therapeutic applications. In particular, their ability to enhance the uptake of drugs through the permeabilization of tissues and cell membranes shows...

Cite
Lajoinie G, De Cock I, Coussios CC, et al. In vitro methods to study bubble-cell interactions: Fundamentals and therapeutic applications. Biomicrofluidics. 2016;10(1):011501doi: 10.1063/1.4940429.
Lajoinie, G., De Cock, I., Coussios, C. C., Lentacker, I., Le Gac, S., Stride, E., & Versluis, M. (2016). In vitro methods to study bubble-cell interactions: Fundamentals and therapeutic applications. Biomicrofluidics, 10(1), 011501. https://doi.org/10.1063/1.4940429
Lajoinie, Guillaume, et al. "In vitro methods to study bubble-cell interactions: Fundamentals and therapeutic applications." Biomicrofluidics vol. 10,1 (2016): 011501. doi: https://doi.org/10.1063/1.4940429
Lajoinie G, De Cock I, Coussios CC, Lentacker I, Le Gac S, Stride E, Versluis M. In vitro methods to study bubble-cell interactions: Fundamentals and therapeutic applications. Biomicrofluidics. 2016 Jan 28;10(1):011501. doi: 10.1063/1.4940429. eCollection 2016 Jan. PMID: 26865903; PMCID: PMC4733084.
Copy Download .nbib Format: NLM
Showing 1 to 6 of 6 entries