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Showing 1 to 9 of 9 entries
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Endogenous Na/K ATPase inhibitor ouabain in critically ill children with lung injury.

Pathophysiology : the official journal of the International Society for Pathophysiology

Eisenhut M, Leppäluoto J.
PMID: 21414760
Pathophysiology. 2011 Jun;18(3):243-5. doi: 10.1016/j.pathophys.2011.02.002. Epub 2011 Mar 17.

OBJECTIVES: To measure ouabain, an endogenous adrenocortical Na/K ATPase inhibitor, in critically ill children with acute lung injury and relate it to parameters reflecting epithelial sodium transport.DESIGN: Prospective observational study.SETTING: Paediatric Intensive Care Unit of Royal Liverpool Children's Hospital.SUBJECTS:...

Association of Physical Activity With Telomere Length Among Elderly Adults - The Oulu Cohort 1945.

Frontiers in physiology

Stenbäck V, Mutt SJ, Leppäluoto J, Gagnon DD, Mäkelä KA, Jokelainen J, Keinänen-Kiukaanniemi S, Herzig KH.
PMID: 31105579
Front Physiol. 2019 Apr 24;10:444. doi: 10.3389/fphys.2019.00444. eCollection 2019.

No abstract available.

(Neuro) Peptides, Physical Activity, and Cognition.

Journal of clinical medicine

Autio J, Stenbäck V, Gagnon DD, Leppäluoto J, Herzig KH.
PMID: 32785144
J Clin Med. 2020 Aug 10;9(8). doi: 10.3390/jcm9082592.

Regular physical activity (PA) improves cognitive functions, prevents brain atrophy, and delays the onset of cognitive decline, dementia, and Alzheimer's disease. Presently, there are no specific recommendations for PA producing positive effects on brain health and little is known...

Step detection and energy expenditure at different speeds by three accelerometers in a controlled environment.

Scientific reports

Stenbäck V, Leppäluoto J, Leskelä N, Viitala L, Vihriälä E, Gagnon D, Tulppo M, Herzig KH.
PMID: 34625578
Sci Rep. 2021 Oct 08;11(1):20005. doi: 10.1038/s41598-021-97299-z.

Physical activity (PA) is one of the most efficient ways to prevent obesity and its associated diseases worldwide. In the USA, less than 10% of the adult population were able to meet the PA recommendations when accelerometers were used...

Step detection and energy expenditure at different speeds by three accelerometers in a controlled environment.

Scientific reports

Stenbäck V, Leppäluoto J, Leskelä N, Viitala L, Vihriälä E, Gagnon D, Tulppo M, Herzig KH.
PMID: 34625578
Sci Rep. 2021 Oct 08;11(1):20005. doi: 10.1038/s41598-021-97299-z.

Physical activity (PA) is one of the most efficient ways to prevent obesity and its associated diseases worldwide. In the USA, less than 10% of the adult population were able to meet the PA recommendations when accelerometers were used...

Effect of Physical Activity on Plasma PCSK9 in Subjects With High Risk for Type 2 Diabetes.

Frontiers in physiology

Mäkelä KA, Leppäluoto J, Jokelainen J, Jämsä T, Keinänen-Kiukaanniemi S, Herzig KH.
PMID: 31114503
Front Physiol. 2019 Apr 30;10:456. doi: 10.3389/fphys.2019.00456. eCollection 2019.

BACKGROUND: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a liver serine protease regulating LDL cholesterol metabolism. PCSK9 binds to LDL receptors and guides them to lysosomes for degradation, thus increasing the amount of circulating LDL cholesterol. The aim of...

Plasma Orexin-A Levels Do Not Undergo Circadian Rhythm in Young Healthy Male Subjects.

Frontiers in endocrinology

Mäkelä KA, Karhu T, Jurado Acosta A, Vakkuri O, Leppäluoto J, Herzig KH.
PMID: 30568633
Front Endocrinol (Lausanne). 2018 Dec 05;9:710. doi: 10.3389/fendo.2018.00710. eCollection 2018.

Orexin-A (OXA) has been originally isolated from a precursor peptide prepro-orexin from the lateral hypothalamus. The orexin system has been attributed to important functions in sleep, arousal and regulation of energy homeostasis. In addition to its high levels in...

PCSK9 Levels and Metabolic Profiles in Elderly Subjects with Different Glucose Tolerance under Statin Therapy.

Journal of clinical medicine

Mäkelä KA, Jokelainen J, Stenbäck V, Auvinen J, Järvelin MR, Tulppo M, Leppäluoto J, Keinänen-Kiukaanniemi S, Herzig KH.
PMID: 33801208
J Clin Med. 2021 Mar 02;10(5). doi: 10.3390/jcm10050994.

Proprotein convertase subtilisin/kexin type 9 (PCSK9) degrades low-density lipoprotein cholesterol (LDL-C) receptors, and thus regulates the LDL-C levels in the circulation. Type 2 diabetics often have elevated LDL-C levels. However, the functions of PCSK9 in patients with alterations of...

Urinary thrombomodulin and catecholamine levels are interrelated in healthy volunteers immersed in cold and warm water.

Temperature (Austin, Tex.)

Pakanen L, Pääkkönen T, Ikäheimo TM, Rintamäki H, Leppäluoto J, Kaija H, Kortelainen ML, Rautio A, Porvari K.
PMID: 27227082
Temperature (Austin). 2015 May 05;3(1):161-6. doi: 10.1080/23328940.2015.1033589. eCollection 2016.

Severe hypothermia has been shown to influence the levels of catecholamines and thrombomodulin, an endothelial protein essentially involved in the regulation of haemostasis and inflammation. A link between thrombomodulin and catecholamines during cold exposure has also been previously suggested....

Showing 1 to 9 of 9 entries