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Showing 1 to 12 of 27 entries
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GLUT1 expression in pediatric adrenocortical tumors: a promising candidate to predict clinical behavior.

Oncotarget

Pinheiro C, Granja S, Longatto-Filho A, Faria AM, Fragoso MCBV, Lovisolo SM, Bonatelli M, Costa RFA, Lerário AM, Almeida MQ, Baltazar F, Zerbini MCN.
PMID: 28969033
Oncotarget. 2017 Jul 10;8(38):63835-63845. doi: 10.18632/oncotarget.19135. eCollection 2017 Sep 08.

BACKGROUND: Discrimination between benign and malignant tumors is a challenging process in pediatric adrenocortical tumors. New insights in the metabolic profile of pediatric adrenocortical tumors may contribute to this distinction, predict prognosis, as well as identify new molecular targets...

Algorithm for the treatment of type 2 diabetes: a position statement of Brazilian Diabetes Society.

Diabetology & metabolic syndrome

Lerario AC, Chacra AR, Pimazoni-Netto A, Malerbi D, Gross JL, Oliveira JE, Gomes MB, Santos RD, Fonseca RM, Betti R, Raduan R.
PMID: 20529311
Diabetol Metab Syndr. 2010 Jun 08;2(1):35. doi: 10.1186/1758-5996-2-35.

The Brazilian Diabetes Society is starting an innovative project of quantitative assessment of medical arguments of and implementing a new way of elaborating SBD Position Statements. The final aim of this particular project is to propose a new Brazilian...

Corrigendum: Transcriptome Analysis Showed a Differential Signature Between Invasive and Non-invasive Corticotrophinomas.

Frontiers in endocrinology

de Araújo LJT, Lerario AM, de Castro M, Martins CS, Bronstein MD, Machado MC, Trarbach EB, Villares Fragoso MCB.
PMID: 31485213
Front Endocrinol (Lausanne). 2019 Aug 22;10:567. doi: 10.3389/fendo.2019.00567. eCollection 2019.

[This corrects the article DOI: 10.3389/fendo.2017.00055.].

APOL1 in an ethnically diverse pediatric population with nephrotic syndrome: implications in focal segmental glomerulosclerosis and other diagnoses.

Pediatric nephrology (Berlin, Germany)

Watanabe A, Guaragna MS, Belangero VMS, Casimiro FMS, Pesquero JB, de Santis Feltran L, Palma LMP, Varela P, de Menezes Neves PDM, Lerario AM, de Souza ML, de Mello MP, de Brito Lutaif ACG, Ferrari CR, Sampson MG, Onuchic LF, Nogueira PCK.
PMID: 33585978
Pediatr Nephrol. 2021 Aug;36(8):2327-2336. doi: 10.1007/s00467-021-04960-w. Epub 2021 Feb 14.

BACKGROUND: APOL1 high-risk genotypes (HRG) are associated with increased risk of kidney disease in individuals of African ancestry. We analyzed the effects of APOL1 risk variants on an ethnically diverse Brazilian pediatric nephrotic syndrome (NS) cohort.METHODS: Multicenter study including...

The Use of Social Media and Digital Devices Among Italian Neurologists.

Frontiers in neurology

Lavorgna L, Brigo F, Abbadessa G, Bucello S, Clerico M, Cocco E, Iodice R, Lanzillo R, Leocani L, Lerario A, Moccia M, Padovani A, Prosperini L, Repice A, Stromillo M, Trojsi F, Mancardi G, Tedeschi G, Bonavita S.
PMID: 32612572
Front Neurol. 2020 Jun 16;11:583. doi: 10.3389/fneur.2020.00583. eCollection 2020.

No abstract available.

Molecular Mechanisms of Stem/Progenitor Cell Maintenance in the Adrenal Cortex.

Frontiers in endocrinology

Lerario AM, Finco I, LaPensee C, Hammer GD.
PMID: 28386245
Front Endocrinol (Lausanne). 2017 Mar 23;8:52. doi: 10.3389/fendo.2017.00052. eCollection 2017.

The adrenal cortex is characterized by three histologically and functionally distinct zones: the outermost zona glomerulosa (zG), the intermediate zona fasciculata, and the innermost zona reticularis. Important aspects of the physiology and maintenance of the adrenocortical stem/progenitor cells have...

Phosphodiesterase 2A and 3B variants are associated with primary aldosteronism.

Endocrine-related cancer

Rassi-Cruz M, Maria AG, Faucz FR, London E, Vilela LAP, Santana LS, Benedetti AFF, Goldbaum TS, Tanno FY, Srougi V, Chambo JL, Pereira MAA, Cavalcante ACBS, Carnevale FC, Pilan B, Bortolotto LA, Drager LF, Lerario AM, Latronico AC, Fragoso MCBV, Mendonca BB, Zerbini MCN, Stratakis CA, Almeida MQ.
PMID: 33112806
Endocr Relat Cancer. 2021 Jan;28(1):1-13. doi: 10.1530/ERC-20-0384.

Familial primary aldosteronism (PA) is rare and mostly diagnosed in early-onset hypertension (HT). However, 'sporadic' bilateral adrenal hyperplasia (BAH) is the most frequent cause of PA and remains without genetic etiology in most cases. Our aim was to investigate...

Glutaminolysis dynamics during astrocytoma progression correlates with tumor aggressiveness.

Cancer & metabolism

Moreira Franco YE, Alves MJ, Uno M, Moretti IF, Trombetta-Lima M, de Siqueira Santos S, Dos Santos AF, Arini GS, Baptista MS, Lerario AM, Oba-Shinjo SM, Marie SKN.
PMID: 33910646
Cancer Metab. 2021 Apr 28;9(1):18. doi: 10.1186/s40170-021-00255-8.

BACKGROUND: Glioblastoma is the most frequent and high-grade adult malignant central nervous system tumor. The prognosis is still poor despite the use of combined therapy involving maximal surgical resection, radiotherapy, and chemotherapy. Metabolic reprogramming currently is recognized as one...

The chromatin remodeler complex ATRX-DAXX-H3.3 and telomere length in meningiomas.

Clinical neurology and neurosurgery

Cavalcante SG, Pereira BJA, Lerario AM, Sola PR, Oba-Shinjo SM, Marie SKN.
PMID: 34624827
Clin Neurol Neurosurg. 2021 Nov;210:106962. doi: 10.1016/j.clineuro.2021.106962. Epub 2021 Oct 06.

ATRX-DAXX-H3.3 chromatin remodeler complex is a well known epigenetic factor responsible for the heterochromatin maintenance and control. ATRX is an important nucleosome controller, especially in tandem repeat regions, and DAXX is a multi-function protein with particular role in histone...

Variants in 46,XY DSD-Related Genes in Syndromic and Non-Syndromic Small for Gestational Age Children with Hypospadias.

Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation

Leitao Braga B, Lisboa Gomes N, Nishi MY, Freire BL, Batista RL, D Faria Junior JA, Funari MFA, Figueredo Benedetti AF, de Moraes Narcizo A, Cavalca Cardoso L, Lerario AM, Guerra-Junior G, Frade Costa EM, Domenice S, Jorge AAL, Mendonca BB.
PMID: 34518484
Sex Dev. 2021 Sep 09;1-7. doi: 10.1159/000518091. Epub 2021 Sep 09.

Hypospadias is a common congenital disorder of male genital formation. Children born small for gestational age (SGA) present a high frequency of hypospadias of undetermined etiology. No previous study investigated the molecular etiology of hypospadias in boys born SGA...

A study of interaction potentials for H2 adsorption in Single Walled Nano Tubes: a possible way to more realistic predictions.

Journal of molecular modeling

Lerario M, Magalhães AL.
PMID: 24893959
J Mol Model. 2014 Jun;20(6):2194. doi: 10.1007/s00894-014-2194-8. Epub 2014 Jun 04.

A comparative analysis of interaction potentials, classified according to the parametrization method, namely Lorentz-Berthelot rules, semi-empirical or ab initio calculations, found their energy depths to scale, respectively, to ca 30K, ca 40K, and ca 60K. We draw the Potential...

Regulation of stem and progenitor cells in the adrenal cortex.

Current opinion in endocrine and metabolic research

Finco I, Mohan DR, Hammer GD, Lerario AM.
PMID: 32258821
Curr Opin Endocr Metab Res. 2019 Oct;8:66-71. doi: 10.1016/j.coemr.2019.07.009. Epub 2019 Aug 06.

The adrenal cortex is an endocrine organ comprised of three histological zones, the outermost zona glomerulosa, the intermediate zona fasciculata, and the innermost zona reticularis. High plasticity of the adrenal gland is supported by pools of stem and progenitor...

Showing 1 to 12 of 27 entries