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Showing 1 to 12 of 111 entries
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Primary care physicians' utilization of type 2 diabetes screening guidelines and referrals to behavioral interventions: a survey-linked retrospective study.

BMJ open diabetes research & care

Mehta S, Mocarski M, Wisniewski T, Gillespie K, Narayan KMV, Lang K.
PMID: 28878936
BMJ Open Diabetes Res Care. 2017 Aug 11;5(1):e000406. doi: 10.1136/bmjdrc-2017-000406. eCollection 2017.

OBJECTIVE: To assess primary care physicians' (PCPs) knowledge of type 2 diabetes screening guidelines (American Diabetes Association (ADA) and 2008 US Preventive Services Task Force (USPSTF)), the alignment between their self-reported adherence and actual practice, and how often PCPs...

Discovery of Benzimidazole CYP11B2 Inhibitors with in Vivo Activity in Rhesus Monkeys.

ACS medicinal chemistry letters

Hoyt SB, Park MK, London C, Xiong Y, Tata J, Bennett DJ, Cooke A, Cai J, Carswell E, Robinson J, MacLean J, Brown L, Belshaw S, Clarkson TR, Liu K, Liang GB, Struthers M, Cully D, Wisniewski T, Ren N, Bopp C, Sok A, Cai TQ, Stribling S, Pai LY, Ma X, Metzger J, Verras A, McMasters D, Chen Q, Tung E, Tang W, Salituro G, Buist N, Kuethe J, Rivera N, Clemas J, Zhou G, Gibson J, Maxwell CA, Lassman M, McLaughlin T, Castro-Perez J, Szeto D, Forrest G, Hajdu R, Rosenbach M, Ali A.
PMID: 26005536
ACS Med Chem Lett. 2015 Apr 07;6(5):573-8. doi: 10.1021/acsmedchemlett.5b00054. eCollection 2015 May 14.

We report the discovery of a benzimidazole series of CYP11B2 inhibitors. Hit-to-lead and lead optimization studies identified compounds such as 32, which displays potent CYP11B2 inhibition, high selectivity versus related CYP targets, and good pharmacokinetic properties in rat and...

The Role of TREM2 in Alzheimer's Disease and Other Neurological Disorders.

Journal of Alzheimer's disease & Parkinsonism

Yaghmoor F, Noorsaeed A, Alsaggaf S, Aljohani W, Scholtzova H, Boutajangout A, Wisniewski T.
PMID: 25664220
J Alzheimers Dis Parkinsonism. 2014 Nov;4(5). doi: 10.4172/2161-0460.1000160.

Alzheimer's disease (AD) is the leading cause of dementia worldwide. Late-onset AD (LOAD), is the most common form of Alzheimer's disease, representing about >95% of cases and early-onset AD represents

[Co-existence of cancer and tuberculosis of the lungs].

Gruzlica (Warsaw, Poland : 1926)

LESNIEWSKA M.
PMID: 14416004
Gruzlica. 1959 Jun;27:519-25.

No abstract available.

Investigation of the surface structure and elastic properties of calcium silicate hydrates at the nanoscale.

Ultramicroscopy

Plassard C, Lesniewska E, Pochard I, Nonat A.
PMID: 15231326
Ultramicroscopy. 2004 Aug;100(3):331-8. doi: 10.1016/j.ultramic.2003.11.012.

This work is the first step towards the understanding of the structure of calcium silicate hydrate (C-S-H), the main constituent of cement paste, at the nanoscale. The first demonstration of atomic-resolution imaging of the (C-S-H) surface with an atomic...

Shear force microscopy with a nanoscale resolution.

Ultramicroscopy

Ndobo-Epoy JP, Lesniewska E, Guicquero JP.
PMID: 15850710
Ultramicroscopy. 2005 Jun;103(3):229-36. doi: 10.1016/j.ultramic.2004.12.003. Epub 2005 Jan 07.

This paper presents a shear force microscope having a nanometric resolution at high scan rates. Current techniques were reviewed and tested, and a design based on the use of a tuning fork is described. The use of a low...

In Vivo EPR For Dosimetry.

Radiation measurements

Swartz HM, Burke G, Coey M, Demidenko E, Dong R, Grinberg O, Hilton J, Iwasaki A, Lesniewski P, Kmiec M, Lo KM, Nicolalde RJ, Ruuge A, Sakata Y, Sucheta A, Walczak T, Williams BB, Mitchell C, Romanyukha A, Schauer DA.
PMID: 18591988
Radiat Meas. 2007 Jul;42(6):1075-1084. doi: 10.1016/j.radmeas.2007.05.023.

As a result of terrorism, accident, or war, populations potentially can be exposed to doses of ionizing radiation that could cause direct clinical effects within days or weeks. There is a critical need to determine the magnitude of the...

Credibility of a smoking questionnaire based on urine cotinine level for patients with bladder cancer - a preliminary report.

Central European journal of urology

Leszniewski J, Pufal E, Wolski Z.
PMID: 24578899
Cent European J Urol. 2011;64(4):229-31. doi: 10.5173/ceju.2011.04.art8. Epub 2011 Dec 09.

An analysis of the reliability of a questionnaire on smoking in 96 patients with transitional cell carcinoma (TCC) of the bladder. The credibility of the questionnaire was evaluated based on the detection of cotinine, an objective marker of tobacco...

Temperature effect on the emission spectra of narrow band Mn.

Physical chemistry chemical physics : PCCP

Lesniewski T, Mahlik S, Grinberg M, Liu RS.
PMID: 29188841
Phys Chem Chem Phys. 2017 Dec 13;19(48):32505-32513. doi: 10.1039/c7cp06548e.

Temperature dependence of the luminescence shape and decay time of narrow band Mn

The use of localized proteomics to identify the drivers of Alzheimer's disease pathogenesis.

Neural regeneration research

Drummond E, Wisniewski T.
PMID: 28761421
Neural Regen Res. 2017 Jun;12(6):912-913. doi: 10.4103/1673-5374.208570.

No abstract available.

Study of persistent luminescence and thermoluminescence in SrSi.

Physical chemistry chemical physics : PCCP

Majewska N, Leśniewski T, Mahlik S, Grinberg M, Chruścińska A, Michalik D, Sopicka-Lizer M.
PMID: 32692338
Phys Chem Chem Phys. 2020 Aug 14;22(30):17152-17159. doi: 10.1039/d0cp01739f. Epub 2020 Jul 21.

The process of persistent luminescence or glow-in-the-dark, the delayed emission of light of irradiated substances, has long fascinated researchers, who have made efforts to explain the underlying physical phenomenon as well as put it to practical use. However, persistent...

Adamts18 modulates the development of the aortic arch and common carotid artery.

iScience

Ye S, Yang N, Lu T, Wu T, Wang L, Pan YH, Cao X, Yuan X, Wisniewski T, Dang S, Zhang W.
PMID: 34189436
iScience. 2021 May 31;24(6):102672. doi: 10.1016/j.isci.2021.102672. eCollection 2021 Jun 25.

Members of a disintegrin and metalloproteinases with thrombospondin motif (ADAMTS) family have been implicated in various vascular diseases. However, their functional roles in early embryonic vascular development are unknown. In this study, we showed that

Showing 1 to 12 of 111 entries