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Limitations of laboratory bioassays: the need for ecosystem-level testing

field stations

Levin SA.
GSID: a9xG4XYRMosJ
KD Kimball, SA Levin - Bioscience, 1985 - academic.oup.com

Laboratory bioassays provide a first step in testing for chemical effects on ecosystems but are inadequate for predicting effects on natural populations and on ecosystem-level …

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Kimball, K. D., & Levin, S. A. (1985). Limitations of laboratory bioassays: the need for ecosystem-level testing. Bioscience, 35(3), 165-171.
Kimball, Kenneth D., and Simon A. Levin. "Limitations of laboratory bioassays: the need for ecosystem-level testing." Bioscience 35.3 (1985): 165-171.
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Practice parameters for the detection of colorectal neoplasms--supporting documentation. The Standards Task Force. AmericanSociety of Colon and Rectal Surgeons.

Diseases of the colon and rectum

Rosen L, Abel ME, Gordon PH, Denstman FJ, Fleshman JW, Hicks TC, Huber PJ, Kennedy HL, Levin SE, Nicholson JD.
PMID: 1582364
Dis Colon Rectum. 1992 Apr;35(4):391-4. doi: 10.1007/BF02048121.

No abstract available.

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Rosen L, Abel ME, Gordon PH, et al. Practice parameters for the detection of colorectal neoplasms--supporting documentation. The Standards Task Force. AmericanSociety of Colon and Rectal Surgeons. Dis Colon Rectum. 1992;35(4):391-4doi: 10.1007/BF02048121.
Rosen, L., Abel, M. E., Gordon, P. H., Denstman, F. J., Fleshman, J. W., Hicks, T. C., Huber, P. J., Kennedy, H. L., Levin, S. E., & Nicholson, J. D. (1992). Practice parameters for the detection of colorectal neoplasms--supporting documentation. The Standards Task Force. AmericanSociety of Colon and Rectal Surgeons. Diseases of the colon and rectum, 35(4), 391-4. https://doi.org/10.1007/BF02048121
Rosen, L, et al. "Practice parameters for the detection of colorectal neoplasms--supporting documentation. The Standards Task Force. AmericanSociety of Colon and Rectal Surgeons." Diseases of the colon and rectum vol. 35,4 (1992): 391-4. doi: https://doi.org/10.1007/BF02048121
Rosen L, Abel ME, Gordon PH, Denstman FJ, Fleshman JW, Hicks TC, Huber PJ, Kennedy HL, Levin SE, Nicholson JD. Practice parameters for the detection of colorectal neoplasms--supporting documentation. The Standards Task Force. AmericanSociety of Colon and Rectal Surgeons. Dis Colon Rectum. 1992 Apr;35(4):391-4. doi: 10.1007/BF02048121. PMID: 1582364.
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Biome-scale nitrogen fixation strategies selected by climatic constraints on nitrogen cycle.

Nature plants

Sheffer E, Batterman SA, Levin SA, Hedin LO.
PMID: 27251717
Nat Plants. 2015 Nov 23;1:15182. doi: 10.1038/nplants.2015.182.

Dinitrogen fixation by plants (in symbiosis with root bacteria) is a major source of new nitrogen for land ecosystems(1). A long-standing puzzle(2) is that trees capable of nitrogen fixation are abundant in nitrogen-rich tropical forests, but absent or restricted...

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Sheffer E, Batterman SA, Levin SA, et al. Biome-scale nitrogen fixation strategies selected by climatic constraints on nitrogen cycle. Nat Plants. 2015;1:15182doi: 10.1038/nplants.2015.182.
Sheffer, E., Batterman, S. A., Levin, S. A., & Hedin, L. O. (2015). Biome-scale nitrogen fixation strategies selected by climatic constraints on nitrogen cycle. Nature plants, 115182. https://doi.org/10.1038/nplants.2015.182
Sheffer, Efrat, et al. "Biome-scale nitrogen fixation strategies selected by climatic constraints on nitrogen cycle." Nature plants vol. 1 (2015): 15182. doi: https://doi.org/10.1038/nplants.2015.182
Sheffer E, Batterman SA, Levin SA, Hedin LO. Biome-scale nitrogen fixation strategies selected by climatic constraints on nitrogen cycle. Nat Plants. 2015 Nov 23;1:15182. doi: 10.1038/nplants.2015.182. PMID: 27251717.
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The Efficacy of Biologic Therapy for the Management of Palmoplantar Psoriasis and Palmoplantar Pustulosis: A Systematic Review.

Dermatology and therapy

Sanchez IM, Sorenson E, Levin E, Liao W.
PMID: 29143230
Dermatol Ther (Heidelb). 2017 Dec;7(4):425-446. doi: 10.1007/s13555-017-0207-0. Epub 2017 Nov 15.

INTRODUCTION: Palmoplantar psoriasis (PP) and palmoplantar pustulosis (PPP) are diseases affecting the hands and/or feet that can cause marked physical discomfort and functional disability. The tumor necrosis factor-alpha antagonists adalimumab, etanercept, and infliximab, the interleukin (IL)-17A inhibitors ixekizumab and...

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Sanchez IM, Sorenson E, Levin E, et al. The Efficacy of Biologic Therapy for the Management of Palmoplantar Psoriasis and Palmoplantar Pustulosis: A Systematic Review. Dermatol Ther (Heidelb). 2017;7(4):425-446doi: 10.1007/s13555-017-0207-0.
Sanchez, I. M., Sorenson, E., Levin, E., & Liao, W. (2017). The Efficacy of Biologic Therapy for the Management of Palmoplantar Psoriasis and Palmoplantar Pustulosis: A Systematic Review. Dermatology and therapy, 7(4), 425-446. https://doi.org/10.1007/s13555-017-0207-0
Sanchez, Isabelle M, et al. "The Efficacy of Biologic Therapy for the Management of Palmoplantar Psoriasis and Palmoplantar Pustulosis: A Systematic Review." Dermatology and therapy vol. 7,4 (2017): 425-446. doi: https://doi.org/10.1007/s13555-017-0207-0
Sanchez IM, Sorenson E, Levin E, Liao W. The Efficacy of Biologic Therapy for the Management of Palmoplantar Psoriasis and Palmoplantar Pustulosis: A Systematic Review. Dermatol Ther (Heidelb). 2017 Dec;7(4):425-446. doi: 10.1007/s13555-017-0207-0. Epub 2017 Nov 15. PMID: 29143230; PMCID: PMC5698206.
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Low-Frequency Measurements of the Cosmic Microwave Background Spectruma.

Annals of the New York Academy of Sciences

Bensadoun M, Bersanelli M, Bonelli G, DE Amici G, Kogut A, Levin S, Limon M, Sironi G, Smoot G, Vinje W.
PMID: 26469497
Ann N Y Acad Sci. 1993 Jun;688:792-4. doi: 10.1111/j.1749-6632.1993.tb43972.x.

No abstract available.

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Bensadoun M, Bersanelli M, Bonelli G, et al. Low-Frequency Measurements of the Cosmic Microwave Background Spectruma. Ann N Y Acad Sci. 1993;688:792-4doi: 10.1111/j.1749-6632.1993.tb43972.x.
Bensadoun, M., Bersanelli, M., Bonelli, G., DE Amici, G., Kogut, A., Levin, S., Limon, M., Sironi, G., Smoot, G., & Vinje, W. (1993). Low-Frequency Measurements of the Cosmic Microwave Background Spectruma. Annals of the New York Academy of Sciences, 688792-4. https://doi.org/10.1111/j.1749-6632.1993.tb43972.x
Bensadoun, M, et al. "Low-Frequency Measurements of the Cosmic Microwave Background Spectruma." Annals of the New York Academy of Sciences vol. 688 (1993): 792-4. doi: https://doi.org/10.1111/j.1749-6632.1993.tb43972.x
Bensadoun M, Bersanelli M, Bonelli G, DE Amici G, Kogut A, Levin S, Limon M, Sironi G, Smoot G, Vinje W. Low-Frequency Measurements of the Cosmic Microwave Background Spectruma. Ann N Y Acad Sci. 1993 Jun;688:792-4. doi: 10.1111/j.1749-6632.1993.tb43972.x. PMID: 26469497.
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Contextual analysis and the success of translational research.

Translational behavioral medicine

Biglan A, Levin ME.
PMID: 27012264
Transl Behav Med. 2016 Mar;6(1):160-6. doi: 10.1007/s13142-015-0362-8.

The success of translational research can ultimately be judged by the degree to which it reduces the incidence and prevalence of psychological, behavioral, and physical disorders and the major factors influencing them. In our view, we currently place insufficient...

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Biglan A, Levin ME. Contextual analysis and the success of translational research. Transl Behav Med. 2016;6(1):160-6doi: 10.1007/s13142-015-0362-8.
Biglan, A., & Levin, M. E. (2016). Contextual analysis and the success of translational research. Translational behavioral medicine, 6(1), 160-6. https://doi.org/10.1007/s13142-015-0362-8
Biglan, Anthony, and Levin, Michael E. "Contextual analysis and the success of translational research." Translational behavioral medicine vol. 6,1 (2016): 160-6. doi: https://doi.org/10.1007/s13142-015-0362-8
Biglan A, Levin ME. Contextual analysis and the success of translational research. Transl Behav Med. 2016 Mar;6(1):160-6. doi: 10.1007/s13142-015-0362-8. PMID: 27012264; PMCID: PMC4807198.
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Correction for Giuggioli et al., Stigmergy, collective actions, and animal social spacing.

Proceedings of the National Academy of Sciences of the United States of America

Giuggioli L, Potts JR, Rubenstein DI, Levin SA.
PMID: 26831063
Proc Natl Acad Sci U S A. 2016 Feb 09;113(6):E812. doi: 10.1073/pnas.1600608113. Epub 2016 Feb 01.

No abstract available.

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Giuggioli L, Potts JR, Rubenstein DI, et al. Correction for Giuggioli et al., Stigmergy, collective actions, and animal social spacing. Proc Natl Acad Sci U S A. 2016;113(6):E812doi: 10.1073/pnas.1600608113.
Giuggioli, L., Potts, J. R., Rubenstein, D. I., & Levin, S. A. (2016). Correction for Giuggioli et al., Stigmergy, collective actions, and animal social spacing. Proceedings of the National Academy of Sciences of the United States of America, 113(6), E812. https://doi.org/10.1073/pnas.1600608113
Giuggioli, Luca, et al. "Correction for Giuggioli et al., Stigmergy, collective actions, and animal social spacing." Proceedings of the National Academy of Sciences of the United States of America vol. 113,6 (2016): E812. doi: https://doi.org/10.1073/pnas.1600608113
Giuggioli L, Potts JR, Rubenstein DI, Levin SA. Correction for Giuggioli et al., Stigmergy, collective actions, and animal social spacing. Proc Natl Acad Sci U S A. 2016 Feb 09;113(6):E812. doi: 10.1073/pnas.1600608113. Epub 2016 Feb 01. PMID: 26831063; PMCID: PMC4760796.
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Interview with Saul Levin, MD, MPA, CEO/Medical Director of the American Psychiatric Association on the 40th Anniversary of the Decision to Remove Homosexuality from the DSM.

LGBT health

Eyler AE, Levin S.
PMID: 26789614
LGBT Health. 2014 Jun;1(2):70-4. doi: 10.1089/lgbt.2014.0011.

No abstract available.

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Eyler AE, Levin S. Interview with Saul Levin, MD, MPA, CEO/Medical Director of the American Psychiatric Association on the 40th Anniversary of the Decision to Remove Homosexuality from the DSM. LGBT Health. 2014;1(2):70-4doi: 10.1089/lgbt.2014.0011.
Eyler, A. E., & Levin, S. (2014). Interview with Saul Levin, MD, MPA, CEO/Medical Director of the American Psychiatric Association on the 40th Anniversary of the Decision to Remove Homosexuality from the DSM. LGBT health, 1(2), 70-4. https://doi.org/10.1089/lgbt.2014.0011
Eyler, A Evan, and Levin, Saul. "Interview with Saul Levin, MD, MPA, CEO/Medical Director of the American Psychiatric Association on the 40th Anniversary of the Decision to Remove Homosexuality from the DSM." LGBT health vol. 1,2 (2014): 70-4. doi: https://doi.org/10.1089/lgbt.2014.0011
Eyler AE, Levin S. Interview with Saul Levin, MD, MPA, CEO/Medical Director of the American Psychiatric Association on the 40th Anniversary of the Decision to Remove Homosexuality from the DSM. LGBT Health. 2014 Jun;1(2):70-4. doi: 10.1089/lgbt.2014.0011. PMID: 26789614.
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Collective behavior as a driver of critical transitions in migratory populations.

Movement ecology

Berdahl A, van Leeuwen A, Levin SA, Torney CJ.
PMID: 27429757
Mov Ecol. 2016 Jul 15;4:18. doi: 10.1186/s40462-016-0083-8. eCollection 2016.

BACKGROUND: Mass migrations are among the most striking examples of animal movement in the natural world. Such migrations are major drivers of ecosystem processes and strongly influence the survival and fecundity of individuals. For migratory animals, a formidable challenge...

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Berdahl A, van Leeuwen A, Levin SA, et al. Collective behavior as a driver of critical transitions in migratory populations. Mov Ecol. 2016;4:18doi: 10.1186/s40462-016-0083-8.
Berdahl, A., van Leeuwen, A., Levin, S. A., & Torney, C. J. (2016). Collective behavior as a driver of critical transitions in migratory populations. Movement ecology, 418. https://doi.org/10.1186/s40462-016-0083-8
Berdahl, Andrew, et al. "Collective behavior as a driver of critical transitions in migratory populations." Movement ecology vol. 4 (2016): 18. doi: https://doi.org/10.1186/s40462-016-0083-8
Berdahl A, van Leeuwen A, Levin SA, Torney CJ. Collective behavior as a driver of critical transitions in migratory populations. Mov Ecol. 2016 Jul 15;4:18. doi: 10.1186/s40462-016-0083-8. eCollection 2016. PMID: 27429757; PMCID: PMC4946155.
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The role of 39 psoriasis risk variants on age of psoriasis onset.

ISRN dermatology

Lu Y, Kane S, Chen H, Leon A, Levin E, Nguyen T, Debbaneh M, Millsop JW, Gupta R, Huynh M, Butler D, Cordoro K, Liao W.
PMID: 24175098
ISRN Dermatol. 2013 Sep 23;2013:203941. doi: 10.1155/2013/203941. eCollection 2013.

Recent genome-wide association studies (GWAS) have identified multiple genetic risk factors for psoriasis, but data on their association with age of onset have been marginally explored. The goal of this study was to evaluate known risk alleles of psoriasis...

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Lu Y, Kane S, Chen H, et al. The role of 39 psoriasis risk variants on age of psoriasis onset. ISRN Dermatol. 2013;2013:203941doi: 10.1155/2013/203941.
Lu, Y., Kane, S., Chen, H., Leon, A., Levin, E., Nguyen, T., Debbaneh, M., Millsop, J. W., Gupta, R., Huynh, M., Butler, D., Cordoro, K., & Liao, W. (2013). The role of 39 psoriasis risk variants on age of psoriasis onset. ISRN dermatology, 2013203941. https://doi.org/10.1155/2013/203941
Lu, Yingchang, et al. "The role of 39 psoriasis risk variants on age of psoriasis onset." ISRN dermatology vol. 2013 (2013): 203941. doi: https://doi.org/10.1155/2013/203941
Lu Y, Kane S, Chen H, Leon A, Levin E, Nguyen T, Debbaneh M, Millsop JW, Gupta R, Huynh M, Butler D, Cordoro K, Liao W. The role of 39 psoriasis risk variants on age of psoriasis onset. ISRN Dermatol. 2013 Sep 23;2013:203941. doi: 10.1155/2013/203941. eCollection 2013. PMID: 24175098; PMCID: PMC3794653.
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Uterine fluid from a mare.

Veterinary clinical pathology

Goldman EE, Grindem CB, McDorman KS, VanCamp S.
PMID: 12075555
Vet Clin Pathol. 1998;27(1):15. doi: 10.1111/j.1939-165x.1998.tb01074.x.

No abstract available.

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Goldman EE, Grindem CB, McDorman KS, et al. Uterine fluid from a mare. Vet Clin Pathol. 1998;27(1):15doi: 10.1111/j.1939-165x.1998.tb01074.x.
Goldman, E. E., Grindem, C. B., McDorman, K. S., & VanCamp, S. (1998). Uterine fluid from a mare. Veterinary clinical pathology, 27(1), 15. https://doi.org/10.1111/j.1939-165x.1998.tb01074.x
Goldman, Elizabeth E., et al. "Uterine fluid from a mare." Veterinary clinical pathology vol. 27,1 (1998): 15. doi: https://doi.org/10.1111/j.1939-165x.1998.tb01074.x
Goldman EE, Grindem CB, McDorman KS, VanCamp S. Uterine fluid from a mare. Vet Clin Pathol. 1998;27(1):15. doi: 10.1111/j.1939-165x.1998.tb01074.x. PMID: 12075555.
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Structural and Magnetochemical Properties of Mono-, Di-, and Trinuclear Manganese(III) Dithiolate Complexes.

Inorganic chemistry

Seela JL, Knapp MJ, Kolack KS, Chang HR, Huffman JC, Hendrickson DN, Christou G.
PMID: 11670303
Inorg Chem. 1998 Feb 09;37(3):516-525. doi: 10.1021/ic970587r.

Aerial oxidation of Mn(II)/ptt(3)(-) (ptt(3)(-) = propane-1,2,3-trithiolate) mixtures gives [Mn(2)(pttd)(2)](2)(-), where pttd(4)(-) is the mono(disulfide) of ptt(3)(-). (NEt(3)Bz)(2)[Mn(2)(pttd)(2)] (2) crystallizes in space group P2(1)/c with (at -158 degrees C) a = 11.540(2) Å, b = 12.115(2) Å, c =...

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Seela JL, Knapp MJ, Kolack KS, et al. Structural and Magnetochemical Properties of Mono-, Di-, and Trinuclear Manganese(III) Dithiolate Complexes. Inorg Chem. 1998;37(3):516-525doi: 10.1021/ic970587r.
Seela, J. L., Knapp, M. J., Kolack, K. S., Chang, H. R., Huffman, J. C., Hendrickson, D. N., & Christou, G. (1998). Structural and Magnetochemical Properties of Mono-, Di-, and Trinuclear Manganese(III) Dithiolate Complexes. Inorganic chemistry, 37(3), 516-525. https://doi.org/10.1021/ic970587r
Seela, Jeffrey L., et al. "Structural and Magnetochemical Properties of Mono-, Di-, and Trinuclear Manganese(III) Dithiolate Complexes." Inorganic chemistry vol. 37,3 (1998): 516-525. doi: https://doi.org/10.1021/ic970587r
Seela JL, Knapp MJ, Kolack KS, Chang HR, Huffman JC, Hendrickson DN, Christou G. Structural and Magnetochemical Properties of Mono-, Di-, and Trinuclear Manganese(III) Dithiolate Complexes. Inorg Chem. 1998 Feb 09;37(3):516-525. doi: 10.1021/ic970587r. PMID: 11670303.
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Showing 1 to 12 of 411 entries