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Showing 1 to 11 of 11 entries
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Involvement of the FOXO6 transcriptional factor in breast carcinogenesis.

Oncotarget

Lallemand F, Petitalot A, Vacher S, de Koning L, Taouis K, Lopez BS, Zinn-Justin S, Dalla-Venezia N, Chemlali W, Schnitzler A, Lidereau R, Bieche I, Caputo SM.
PMID: 29484124
Oncotarget. 2017 Dec 30;9(7):7464-7475. doi: 10.18632/oncotarget.23779. eCollection 2018 Jan 26.

In mammals, FOXO transcriptional factors form a family of four members (FOXO1, 3, 4, and 6) involved in the modulation proliferation, apoptosis, and carcinogenesis. The role of the FOXO family in breast cancer remains poorly elucidated. According to the...

Corrigendum: A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma.

Nature

Bertolotto C, Lesueur F, Giuliano S, Strub T, de Lichy M, Bille K, Dessen P, d'Hayer B, Mohamdi H, Remenieras A, Maubec E, de la Fouchardière A, Molinié V, Vabres P, Dalle S, Poulalhon N, Martin-Denavit T, Thomas L, Andry-Benzaquen P, Dupin N, Boitier F, Rossi A, Perrot JL, Labeille B, Robert C, Escudier B, Caron O, Brugières L, Saule S, Gardie B, Gad S, Richard S, Couturier J, Teh BT, Ghiorzo P, Pastorino L, Puig S, Badenas C, Olsson H, Ingvar C, Rouleau E, Lidereau R, Bahadoran P, Vielh P, Corda E, Blanché H, Zelenika D, Galan P, Chaudru V, Lenoir GM, Lathrop M, Davidson I, Avril MF, Demenais F, Ballotti R, Bressac-de Paillerets B.
PMID: 26633630
Nature. 2016 Mar 03;531(7592):126. doi: 10.1038/nature16158. Epub 2015 Dec 02.

No abstract available.

Sublocalization of smallest common regions of deletion on chromosome 17q12-q23 in sporadic primary breast-tumors.

Oncology reports

Champeme M, Mazoyer S, Stoppalyonnet D, Bieche I, Ithier G, Sobol H, Nogues C, Lidereau R.
PMID: 21597825
Oncol Rep. 1995 Sep;2(5):825-31. doi: 10.3892/or.2.5.825.

Frequent loss of heterozygosity (LOH) on the long arm of chromosome 17 has been described in breast tumor DNAs by a number of groups, and recent fine genetic mapping and cloning of an inherited breast-ovarian cancer susceptibility locus (BRCA1)...

Novel germline MET pathogenic variants in French patients with papillary renal cell carcinomas type I.

Human mutation

Sebai M, Tulasne D, Caputo SM, Verkarre V, Fernandes M, Reinhart F, Adams S, Maugard C, Caron O, Guillaud-Bataille M, Berthet P, Bignon YJ, Bressac-de Paillerets B, Burnichon N, Chiesa J, Giraud S, Lejeune S, Limacher JM, de Pauw A, Stoppa-Lyonnet D, Zattara-Cannoni H, Deveaux S, Lidereau R, Richard S, Rouleau E.
PMID: 34882875
Hum Mutat. 2021 Dec 09; doi: 10.1002/humu.24313. Epub 2021 Dec 09.

Hereditary papillary renal cell carcinoma (HPRC) is a rare inherited renal cancer syndrome characterized by bilateral and multifocal papillary type 1 renal tumors (PRCC1). Activating germline pathogenic variants of MET gene were identified in HPRC families. We reviewed the...

Identification of new candidate therapeutic target genes in triple-negative breast cancer.

Genes & cancer

Glénisson M, Vacher S, Callens C, Susini A, Cizeron-Clairac G, Le Scodan R, Meseure D, Lerebours F, Spyratos F, Lidereau R, Bièche I.
PMID: 22893791
Genes Cancer. 2012 Jan;3(1):63-70. doi: 10.1177/1947601912449832.

Triple-negative breast cancer (TNBC) is a subgroup of breast cancer that is negative for estrogen and progesterone receptor and ERBB2 protein expression. It is characterized by its aggressive behavior and by the lack of targeted therapies. To identify new...

5' Region Large Genomic Rearrangements in the .

Cancers

Caputo SM, Telly D, Briaux A, Sesen J, Ceppi M, Bonnet F, Bourdon V, Coulet F, Castera L, Delnatte C, Hardouin A, Mazoyer S, Schultz I, Sevenet N, Uhrhammer N, Bonnet C, Tilkin-Mariamé AF, Houdayer C, Moncoutier V, Andrieu C, French Covar Group Collaborators, Bièche I, Stern MH, Stoppa-Lyonnet D, Lidereau R, Toulas C, Rouleau E.
PMID: 34202044
Cancers (Basel). 2021 Jun 25;13(13). doi: 10.3390/cancers13133171.

BACKGROUND: Large genomic rearrangements (LGR) in METHODS: DNA from 20 families with one apparent duplication and nine deletions was analyzed with a dedicated comparative genomic hybridization (CGH) array, high-resolution BRCA1 Genomic Morse Codes analysis and Sanger sequencing.RESULTS: The apparent...

Biopathological Significance of TLR9 Expression in Cancer Cells and Tumor Microenvironment Across Invasive Breast Carcinomas Subtypes.

Cancer microenvironment : official journal of the International Cancer Microenvironment Society

Meseure D, Vacher S, Drak Alsibai K, Trassard M, Nicolas A, Leclere R, Lerebours F, Guinebretiere JM, Marangoni E, Lidereau R, Bieche I.
PMID: 27392414
Cancer Microenviron. 2016 Dec;9(2):107-118. doi: 10.1007/s12307-016-0186-1. Epub 2016 Jul 09.

Toll-like receptors (TLRs) are pattern recognition receptors mainly expressed by cells of the immune system but also by epithelial tumor cells. Little is known about expression patterns of TLR genes in breast tumors, and their clinical significance is unclear....

Self-other recognition impairments in individuals with schizophrenia: a new experimental paradigm using a double mirror.

NPJ schizophrenia

Keromnes G, Motillon T, Coulon N, Berthoz A, Du Boisgueheneuc F, Wehrmann M, Martin B, Thirioux B, Bonnot O, Ridereau R, Bellissant E, Drapier D, Levoyer D, Jaafari N, Tordjman S.
PMID: 30487540
NPJ Schizophr. 2018 Nov 28;4(1):24. doi: 10.1038/s41537-018-0065-5.

Clinical observations suggest early self-consciousness disturbances in schizophrenia. A double mirror combining the images of two individuals sitting on each side of the mirror was used to study self-other differentiation in 12 individuals with early onset schizophrenia (EOS) and...

Trimodal GSTT1 and GSTM1 genotyping assay by real-time PCR.

The International journal of biological markers

Girault I, Lidereau R, Biche I.
PMID: 28207141
Int J Biol Markers. 2005 Apr - Jun;20(2):81-86. doi: 10.5301/JBM.2008.2569.

The GSTT1 and GSTM1 genes are characterized by the existence of a GST*0 null allele responsible for a lack of enzyme activity, with the respective null genotypes GSTT1*0/0 and GSTM1*0/0. The three resulting genotypes (GSTs*1/1, *1/0 and *0/0) are...

Allelic loss at chromosome 8p in human breast-cancer.

Oncology reports

Kerangueven F, Adelaide J, Dib A, Longy M, Lidereau R, Pebusque M, Jacquemier J, Birnbaum D.
PMID: 21607372
Oncol Rep. 1994 Mar;1(2):393-5. doi: 10.3892/or.1.2.393.

Loss of heterozygosity (LOH) at loci from the short arm of chromosome 8 has been shown to occur in several types of carcinomas. The consensus deletion region has been recently mapped at 8p21-p22, distal to D8S283 and NEFL loci,...

Molecular features of untreated breast cancer and initial metastatic event inform clinical decision-making and predict outcome: long-term results of ESOPE, a single-arm prospective multicenter study.

Genome medicine

Callens C, Driouch K, Boulai A, Tariq Z, Comte A, Berger F, Belin L, Bièche I, Servois V, Legoix P, Bernard V, Baulande S, Chemlali W, Bidard FC, Fourchotte V, Salomon AV, Brain E, Lidereau R, Bachelot T, Saghatchian M, Campone M, Giacchetti S, Zafrani BS, Cottu P.
PMID: 33722295
Genome Med. 2021 Mar 15;13(1):44. doi: 10.1186/s13073-021-00862-6.

BACKGROUND: Prognosis evaluation of advanced breast cancer and therapeutic strategy are mostly based on clinical features of advanced disease and molecular profiling of the primary tumor. Very few studies have evaluated the impact of metastatic subtyping during the initial...

Showing 1 to 11 of 11 entries