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Showing 1 to 6 of 6 entries
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Synthetic Triterpenoid RTA-408: Limits Radiation Damage to Normal Tissue.

The Laryngoscope

Luginbuhl AJ, Hobelmann K, Rodin J, Shukla S, Rodeck U, Linnenbach A.
PMID: 34709651
Laryngoscope. 2021 Oct 28; doi: 10.1002/lary.29930. Epub 2021 Oct 28.

OBJECTIVES/HYPOTHESIS: To assess the efficacy and mechanism of action of a novel approach to mitigate acute and chronic radiation toxicity in a validated animal model.STUDY DESIGN: Randomized, prospective study using an in vivo rat model.METHODS: Experimental animal study utilizing...

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Luginbuhl AJ, Hobelmann K, Rodin J, et al. Synthetic Triterpenoid RTA-408: Limits Radiation Damage to Normal Tissue. Laryngoscope. 2021;doi: 10.1002/lary.29930.
Luginbuhl, A. J., Hobelmann, K., Rodin, J., Shukla, S., Rodeck, U., & Linnenbach, A. (2021). Synthetic Triterpenoid RTA-408: Limits Radiation Damage to Normal Tissue. The Laryngoscope, . https://doi.org/10.1002/lary.29930
Luginbuhl, Adam J, et al. "Synthetic Triterpenoid RTA-408: Limits Radiation Damage to Normal Tissue." The Laryngoscope vol. (2021). doi: https://doi.org/10.1002/lary.29930
Luginbuhl AJ, Hobelmann K, Rodin J, Shukla S, Rodeck U, Linnenbach A. Synthetic Triterpenoid RTA-408: Limits Radiation Damage to Normal Tissue. Laryngoscope. 2021 Oct 28; doi: 10.1002/lary.29930. Epub 2021 Oct 28. PMID: 34709651.
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Tadalafil enhances immune signatures in response to neoadjuvant nivolumab in resectable head and neck squamous cell carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Luginbuhl AJ, Johnson JM, Harshyne LA, Linnenbach AJ, Shukla SK, Alnemri A, Kumar G, Cognetti DM, Curry JM, Kotlov N, Antysheva Z, Degryse S, Mannion K, Gibson MK, Netterville J, Brown B, Axelrod R, Zinner R, Tuluc M, Gargano S, Leiby BE, Shimada A, Mahoney MG, Martinez-Outschoorn U, Rodeck U, Kim YJ, South AP, Argiris A.
PMID: 34911681
Clin Cancer Res. 2021 Dec 15; doi: 10.1158/1078-0432.CCR-21-1816. Epub 2021 Dec 15.

PURPOSE: We hypothesize the addition of the phosphodiesterase 5-inhibitor tadalafil to the PD-1 inhibitor nivolumab, is safe and will augment immune-mediated antitumor responses in previously untreated head and neck squamous cell carcinoma (HNSCC).PATIENTS AND METHODS: We conducted a 2-arm...

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Luginbuhl AJ, Johnson JM, Harshyne LA, et al. Tadalafil enhances immune signatures in response to neoadjuvant nivolumab in resectable head and neck squamous cell carcinoma. Clin Cancer Res. 2021;doi: 10.1158/1078-0432.CCR-21-1816.
Luginbuhl, A. J., Johnson, J. M., Harshyne, L. A., Linnenbach, A. J., Shukla, S. K., Alnemri, A., Kumar, G., Cognetti, D. M., Curry, J. M., Kotlov, N., Antysheva, Z., Degryse, S., Mannion, K., Gibson, M. K., Netterville, J., Brown, B., Axelrod, R., Zinner, R., Tuluc, M., Gargano, S., Leiby, B. E., Shimada, A., Mahoney, M. G., Martinez-Outschoorn, U., Rodeck, U., Kim, Y. J., South, A. P., & Argiris, A. (2021). Tadalafil enhances immune signatures in response to neoadjuvant nivolumab in resectable head and neck squamous cell carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research, . https://doi.org/10.1158/1078-0432.CCR-21-1816
Luginbuhl, Adam J, et al. "Tadalafil enhances immune signatures in response to neoadjuvant nivolumab in resectable head and neck squamous cell carcinoma." Clinical cancer research : an official journal of the American Association for Cancer Research vol. (2021). doi: https://doi.org/10.1158/1078-0432.CCR-21-1816
Luginbuhl AJ, Johnson JM, Harshyne LA, Linnenbach AJ, Shukla SK, Alnemri A, Kumar G, Cognetti DM, Curry JM, Kotlov N, Antysheva Z, Degryse S, Mannion K, Gibson MK, Netterville J, Brown B, Axelrod R, Zinner R, Tuluc M, Gargano S, Leiby BE, Shimada A, Mahoney MG, Martinez-Outschoorn U, Rodeck U, Kim YJ, South AP, Argiris A. Tadalafil enhances immune signatures in response to neoadjuvant nivolumab in resectable head and neck squamous cell carcinoma. Clin Cancer Res. 2021 Dec 15; doi: 10.1158/1078-0432.CCR-21-1816. Epub 2021 Dec 15. PMID: 34911681.
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Tadalafil enhances immune signatures in response to neoadjuvant nivolumab in resectable head and neck squamous cell carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Luginbuhl AJ, Johnson JM, Harshyne LA, Linnenbach AJ, Shukla SK, Alnemri A, Kumar G, Cognetti DM, Curry JM, Kotlov N, Antysheva Z, Degryse S, Mannion K, Gibson MK, Netterville J, Brown B, Axelrod R, Zinner R, Tuluc M, Gargano S, Leiby BE, Shimada A, Mahoney MG, Martinez-Outschoorn U, Rodeck U, Kim YJ, South AP, Argiris A.
PMID: 34911681
Clin Cancer Res. 2021 Dec 15; doi: 10.1158/1078-0432.CCR-21-1816. Epub 2021 Dec 15.

PURPOSE: We hypothesize the addition of the phosphodiesterase 5-inhibitor tadalafil to the PD-1 inhibitor nivolumab, is safe and will augment immune-mediated antitumor responses in previously untreated head and neck squamous cell carcinoma (HNSCC).PATIENTS AND METHODS: We conducted a 2-arm...

Cite
Luginbuhl AJ, Johnson JM, Harshyne LA, et al. Tadalafil enhances immune signatures in response to neoadjuvant nivolumab in resectable head and neck squamous cell carcinoma. Clin Cancer Res. 2021;doi: 10.1158/1078-0432.CCR-21-1816.
Luginbuhl, A. J., Johnson, J. M., Harshyne, L. A., Linnenbach, A. J., Shukla, S. K., Alnemri, A., Kumar, G., Cognetti, D. M., Curry, J. M., Kotlov, N., Antysheva, Z., Degryse, S., Mannion, K., Gibson, M. K., Netterville, J., Brown, B., Axelrod, R., Zinner, R., Tuluc, M., Gargano, S., Leiby, B. E., Shimada, A., Mahoney, M. G., Martinez-Outschoorn, U., Rodeck, U., Kim, Y. J., South, A. P., & Argiris, A. (2021). Tadalafil enhances immune signatures in response to neoadjuvant nivolumab in resectable head and neck squamous cell carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research, . https://doi.org/10.1158/1078-0432.CCR-21-1816
Luginbuhl, Adam J, et al. "Tadalafil enhances immune signatures in response to neoadjuvant nivolumab in resectable head and neck squamous cell carcinoma." Clinical cancer research : an official journal of the American Association for Cancer Research vol. (2021). doi: https://doi.org/10.1158/1078-0432.CCR-21-1816
Luginbuhl AJ, Johnson JM, Harshyne LA, Linnenbach AJ, Shukla SK, Alnemri A, Kumar G, Cognetti DM, Curry JM, Kotlov N, Antysheva Z, Degryse S, Mannion K, Gibson MK, Netterville J, Brown B, Axelrod R, Zinner R, Tuluc M, Gargano S, Leiby BE, Shimada A, Mahoney MG, Martinez-Outschoorn U, Rodeck U, Kim YJ, South AP, Argiris A. Tadalafil enhances immune signatures in response to neoadjuvant nivolumab in resectable head and neck squamous cell carcinoma. Clin Cancer Res. 2021 Dec 15; doi: 10.1158/1078-0432.CCR-21-1816. Epub 2021 Dec 15. PMID: 34911681.
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Positive Childhood Experiences and Adult Mental and Relational Health in a Statewide Sample: Associations Across Adverse Childhood Experiences Levels.

JAMA pediatrics

Bethell C, Jones J, Gombojav N, Linkenbach J, Sege R.
PMID: 31498386
JAMA Pediatr. 2019 Nov 01;173(11):e193007. doi: 10.1001/jamapediatrics.2019.3007. Epub 2019 Nov 04.

IMPORTANCE: Associations between adverse childhood experiences (ACEs) and risks for adult depression, poor mental health, and insufficient social and emotional support have been documented. Less is known about how positive childhood experiences (PCEs) co-occur with and may modulate the...

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Bethell C, Jones J, Gombojav N, et al. Positive Childhood Experiences and Adult Mental and Relational Health in a Statewide Sample: Associations Across Adverse Childhood Experiences Levels. JAMA Pediatr. 2019;173(11):e193007doi: 10.1001/jamapediatrics.2019.3007.
Bethell, C., Jones, J., Gombojav, N., Linkenbach, J., & Sege, R. (2019). Positive Childhood Experiences and Adult Mental and Relational Health in a Statewide Sample: Associations Across Adverse Childhood Experiences Levels. JAMA pediatrics, 173(11), e193007. https://doi.org/10.1001/jamapediatrics.2019.3007
Bethell, Christina, et al. "Positive Childhood Experiences and Adult Mental and Relational Health in a Statewide Sample: Associations Across Adverse Childhood Experiences Levels." JAMA pediatrics vol. 173,11 (2019): e193007. doi: https://doi.org/10.1001/jamapediatrics.2019.3007
Bethell C, Jones J, Gombojav N, Linkenbach J, Sege R. Positive Childhood Experiences and Adult Mental and Relational Health in a Statewide Sample: Associations Across Adverse Childhood Experiences Levels. JAMA Pediatr. 2019 Nov 01;173(11):e193007. doi: 10.1001/jamapediatrics.2019.3007. Epub 2019 Nov 04. PMID: 31498386; PMCID: PMC6735495.
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Positive Childhood Experiences and Adult Mental and Relational Health in a Statewide Sample: Associations Across Adverse Childhood Experiences Levels.

JAMA pediatrics

Bethell C, Jones J, Gombojav N, Linkenbach J, Sege R.
PMID: 31498386
JAMA Pediatr. 2019 Nov 01;173(11):e193007. doi: 10.1001/jamapediatrics.2019.3007. Epub 2019 Nov 04.

IMPORTANCE: Associations between adverse childhood experiences (ACEs) and risks for adult depression, poor mental health, and insufficient social and emotional support have been documented. Less is known about how positive childhood experiences (PCEs) co-occur with and may modulate the...

Cite
Bethell C, Jones J, Gombojav N, et al. Positive Childhood Experiences and Adult Mental and Relational Health in a Statewide Sample: Associations Across Adverse Childhood Experiences Levels. JAMA Pediatr. 2019;173(11):e193007doi: 10.1001/jamapediatrics.2019.3007.
Bethell, C., Jones, J., Gombojav, N., Linkenbach, J., & Sege, R. (2019). Positive Childhood Experiences and Adult Mental and Relational Health in a Statewide Sample: Associations Across Adverse Childhood Experiences Levels. JAMA pediatrics, 173(11), e193007. https://doi.org/10.1001/jamapediatrics.2019.3007
Bethell, Christina, et al. "Positive Childhood Experiences and Adult Mental and Relational Health in a Statewide Sample: Associations Across Adverse Childhood Experiences Levels." JAMA pediatrics vol. 173,11 (2019): e193007. doi: https://doi.org/10.1001/jamapediatrics.2019.3007
Bethell C, Jones J, Gombojav N, Linkenbach J, Sege R. Positive Childhood Experiences and Adult Mental and Relational Health in a Statewide Sample: Associations Across Adverse Childhood Experiences Levels. JAMA Pediatr. 2019 Nov 01;173(11):e193007. doi: 10.1001/jamapediatrics.2019.3007. Epub 2019 Nov 04. PMID: 31498386; PMCID: PMC6735495.
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Practitioner Experience With Mistreated Older Adults Who Have Dementia: Understanding Contextual Influences and Consequences.

Journal of interpersonal violence

Lindenbach J, Morgan D, Larocque S, Jacklin K.
PMID: 32713294
J Interpers Violence. 2020 Jul 26;886260520943717. doi: 10.1177/0886260520943717. Epub 2020 Jul 26.

Studies of mistreatment of older adults have revealed alarmingly higher prevalence rates of mistreatment of those who have dementia. When the mistreatment occurs within the context of the home and is perpetrated by a family caregiver, it may remain...

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Lindenbach J, Morgan D, Larocque S, et al. Practitioner Experience With Mistreated Older Adults Who Have Dementia: Understanding Contextual Influences and Consequences. J Interpers Violence. 2020;886260520943717doi: 10.1177/0886260520943717.
Lindenbach, J., Morgan, D., Larocque, S., & Jacklin, K. (2020). Practitioner Experience With Mistreated Older Adults Who Have Dementia: Understanding Contextual Influences and Consequences. Journal of interpersonal violence, 886260520943717. https://doi.org/10.1177/0886260520943717
Lindenbach, Jeannette, et al. "Practitioner Experience With Mistreated Older Adults Who Have Dementia: Understanding Contextual Influences and Consequences." Journal of interpersonal violence vol. (2020): 886260520943717. doi: https://doi.org/10.1177/0886260520943717
Lindenbach J, Morgan D, Larocque S, Jacklin K. Practitioner Experience With Mistreated Older Adults Who Have Dementia: Understanding Contextual Influences and Consequences. J Interpers Violence. 2020 Jul 26;886260520943717. doi: 10.1177/0886260520943717. Epub 2020 Jul 26. PMID: 32713294.
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Showing 1 to 6 of 6 entries