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Showing 1 to 12 of 32 entries
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The impact of stereotactic radiosurgery in the management of neurofibromatosis type 2-related vestibular schwannomas.

Surgical neurology international

Lustgarten L.
PMID: 23682341
Surg Neurol Int. 2013 Apr 17;4:S151-5. doi: 10.4103/2152-7806.110663. Print 2013.

Although there is an ongoing debate about the ideal management of vestibular schwannomas, radiosurgical treatment has become popular in the past decade with good to excellent results reported. Given the young age at presentation, the bilateral nature of vestibular...

Structure of the crystalline complex of deoxycytidylyl-3',5'-guanosine (3',5'-dCpdG) cocrystallized with ribonuclease at 1.9 A resolution.

Acta crystallographica. Section D, Biological crystallography

Listgarten JN, Maes D, Wyns L, Aguilar CF, Palmer RA.
PMID: 15299807
Acta Crystallogr D Biol Crystallogr. 1995 Sep 01;51:767-71. doi: 10.1107/S0907444995001570.

The X-ray structure of bovine ribonuclease A cocrystallized with the dinucleotide deoxycytidylyl-3',5'-guanosine has been determined at 1.9 A resolution and refined by restrained least squares to R = 0.218 for 7807 reflections. The structure established that the recently observed...

PERSONALIZED MEDICINE: FROM GENOTYPES AND MOLECULAR PHENOTYPES TOWARDS COMPUTED THERAPY.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing

Stegle O, Brenner SE, Morris Q, Listgarten J.
PMID: 23424122
Pac Symp Biocomput. 2013;18:171-174.

No abstract available.

Letters to the Editor.

Journal of periodontology

Coatoam GW, Sussman HI, Moss SS, Listgarten MA, Genco RJ, Peros WJ, Greenstein G, Mishkin DJ, Gellin RG.
PMID: 29539804
J Periodontol. 1993 Sep;64(9):917-920. doi: 10.1902/jop.1993.64.9.917.

No abstract available.

Classifying Aging As a Disease: The Role of Microbes.

Frontiers in genetics

Lustgarten MS.
PMID: 27990156
Front Genet. 2016 Dec 01;7:212. doi: 10.3389/fgene.2016.00212. eCollection 2016.

No abstract available.

Letter to the Editors.

Journal of periodontology

Listgarten MA, Saglie R, Holen S.
PMID: 29539670
J Periodontol. 1988 Jun;59(6):412-413. doi: 10.1902/jop.1988.59.6.412.

No abstract available.

Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs.

Nature biomedical engineering

Listgarten J, Weinstein M, Kleinstiver BP, Sousa AA, Joung JK, Crawford J, Gao K, Hoang L, Elibol M, Doench JG, Fusi N.
PMID: 29998038
Nat Biomed Eng. 2018 Jan;2(1):38-47. doi: 10.1038/s41551-017-0178-6. Epub 2018 Jan 10.

The CRISPR-Cas9 system provides unprecedented genome editing capabilities. However, off-target effects lead to sub-optimal usage and additionally are a bottleneck in the development of therapeutic uses. Herein, we introduce the first machine learning-based approach to off-target prediction, yielding a...

Learning protein fitness models from evolutionary and assay-labeled data.

Nature biotechnology

Hsu C, Nisonoff H, Fannjiang C, Listgarten J.
PMID: 35039677
Nat Biotechnol. 2022 Jan 17; doi: 10.1038/s41587-021-01146-5. Epub 2022 Jan 17.

Machine learning-based models of protein fitness typically learn from either unlabeled, evolutionarily related sequences or variant sequences with experimentally measured labels. For regimes where only limited experimental data are available, recent work has suggested methods for combining both sources...

In silico insights into potential gut microbial modulation of NAD+ metabolism and longevity.

Journal of biochemical and molecular toxicology

Salekeen R, Siam MHB, Sharif DI, Lustgarten MS, Billah MM, Islam KMD.
PMID: 34580953
J Biochem Mol Toxicol. 2021 Sep 27;e22925. doi: 10.1002/jbt.22925. Epub 2021 Sep 27.

Recent evidence has prompted the notion of gut-microbial signatures as an indirect marker of aging and aging-associated decline in humans. However, the underlying host-symbiont molecular interactions contributing to these signatures remain poorly understood. In this study, we address this...

The Use of Oligo Fucoidan in Cancer Bearing Dogs Undergoing Chemotherapy: A Double-Blinded Study.

Topics in companion animal medicine

Post GS, Lustgarten J.
PMID: 34864255
Top Companion Anim Med. 2021 Dec 02;46:100616. doi: 10.1016/j.tcam.2021.100616. Epub 2021 Dec 02.

We evaluated the effect of oligo fucoidan (Laminina Japonica) derived from oceanic brown seaweed on the quality of life in dogs with cancer undergoing chemotherapy in a double-blinded case control study. Included in this prospective study were 100 dogs...

Bachmann's bundle potential during atrial lead placement: a case series.

Heart rhythm

Infeld M, Habel N, Wahlberg K, Meagher S, Meyer M, Lustgarten D.
PMID: 34775070
Heart Rhythm. 2021 Nov 11; doi: 10.1016/j.hrthm.2021.11.015. Epub 2021 Nov 11.

No abstract available.

The use of Oligo Fucoidan in Cancer Bearing Dogs Undergoing Chemotherapy: a double-blinded study.

Topics in companion animal medicine

Post GS, Lustgarten J.
PMID: 34864255
Top Companion Anim Med. 2021 Dec 02;100616. doi: 10.1016/j.tcam.2021.100616. Epub 2021 Dec 02.

We evaluated the effect of oligo fucoidan (Laminina Japonica) derived from oceanic brown seaweed on the quality of life in dogs with cancer undergoing chemotherapy in a double-blinded case control study. Included in this prospective study were 100 dogs...

Showing 1 to 12 of 32 entries