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Showing 1 to 12 of 53 entries
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Sucrose Synthase in Wild Tomato, Lycopersicon chmielewskii, and Tomato Fruit Sink Strength.

Plant physiology

Sun J, Loboda T, Sung SJ, Black CC.
PMID: 16668741
Plant Physiol. 1992 Mar;98(3):1163-9. doi: 10.1104/pp.98.3.1163.

Here it is reported that sucrose synthase can be readily measured in growing wild tomato fruits (Lycopersicon chmielewskii) when suitable methods are adopted during fruit extraction. The enzyme also was present in fruit pericarp tissues, in seeds, and in...

Characterization of Sucrolysis via the Uridine Diphosphate and Pyrophosphate-Dependent Sucrose Synthase Pathway.

Plant physiology

Xu DP, Sung SJ, Loboda T, Kormanik PP, Black CC.
PMID: 16666820
Plant Physiol. 1989 Jun;90(2):635-42. doi: 10.1104/pp.90.2.635.

The breakdown of sucrose to feed both hexoses into glycolytic carbon flow can occur by the sucrose synthase pathway. This uridine diphosphate (UDP) and pyrophosphate (PPi)-dependent pathway was biochemically characterized using soluble extracts from several plants. The sucrolysis process...

Extremely low-phase-noise SAW resonators and oscillators: design and performance.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control

Montress GK, Parker TE, Loboda MJ, Greer JA.
PMID: 18290201
IEEE Trans Ultrason Ferroelectr Freq Control. 1988;35(6):657-67. doi: 10.1109/58.9321.

The authors describe prototype low-noise SAW (surface acoustic wave) resonator oscillators which have demonstrated state-of-the-art phase-noise performance not only at their fundamental operating frequencies in the 400- to 600-MHz range but also after 16x frequency multiplication to X-band as...

Diurnal variation of the human adipose transcriptome and the link to metabolic disease.

BMC medical genomics

Loboda A, Kraft WK, Fine B, Joseph J, Nebozhyn M, Zhang C, He Y, Yang X, Wright C, Morris M, Chalikonda I, Ferguson M, Emilsson V, Leonardson A, Lamb J, Dai H, Schadt E, Greenberg HE, Lum PY.
PMID: 19203388
BMC Med Genomics. 2009 Feb 09;2:7. doi: 10.1186/1755-8794-2-7.

BACKGROUND: Circadian (diurnal) rhythm is an integral part of the physiology of the body; specifically, sleep, feeding behavior and metabolism are tightly linked to the light-dark cycle dictated by earth's rotation.METHODS: The present study examines the effect of diurnal...

Towards hybrid density functional calculations of molecular crystals via fragment-based methods.

The Journal of chemical physics

Loboda OA, Dolgonos GA, Boese AD.
PMID: 30278654
J Chem Phys. 2018 Sep 28;149(12):124104. doi: 10.1063/1.5046908.

We introduce and employ two QM:QM schemes (a quantum mechanical method embedded into another quantum mechanical method) and report their performance for the X23 set of molecular crystals. We furthermore present the theory to calculate the stress tensors necessary...

Dynophore-Based Approach in Virtual Screening: A Case of Human DNA Topoisomerase IIα.

International journal of molecular sciences

Janežič M, Valjavec K, Loboda KB, Herlah B, Ogris I, Kozorog M, Podobnik M, Grdadolnik SG, Wolber G, Perdih A.
PMID: 34948269
Int J Mol Sci. 2021 Dec 15;22(24). doi: 10.3390/ijms222413474.

In this study, we utilized human DNA topoisomerase IIα as a model target to outline a dynophore-based approach to catalytic inhibitor design. Based on MD simulations of a known catalytic inhibitor and the native ATP ligand analog, AMP-PNP, we...

Reverse Translating Molecular Determinants of Anti-Programmed Death 1 Immunotherapy Response in Mouse Syngeneic Tumor Models.

Molecular cancer therapeutics

Georgiev P, Muise ES, Linn DE, Hinton MC, Wang Y, Cai M, Cadzow L, Wilson DC, Sukumar S, Caniga M, Chen L, Xiao H, Yearley JH, Sriram V, Nebozhyn M, Sathe M, Blumenschein WM, Kerr KS, Hirsch HA, Javaid S, Olow AK, Moy LY, Chiang DY, Loboda A, Cristescu R, Sadekova S, Long BJ, McClanahan TK, Pinheiro EM.
PMID: 34965960
Mol Cancer Ther. 2021 Dec 29; doi: 10.1158/1535-7163.MCT-21-0561. Epub 2021 Dec 29.

Targeting the PD-1/PD-L1 pathway with immunotherapy has revolutionized the treatment of many cancers. Somatic tumor mutational burden (TMB) and T-cell-inflamed gene expression profile (GEP) are clinically validated pan-tumor genomic biomarkers that can predict responsiveness to anti-PD-1/PD-L1 monotherapy in many...

Equation of state modeling with pseudoatom molecular dynamics.

Physical review. E

Ovechkin AA, Loboda PA, Falkov AL, Sapozhnikov PA.
PMID: 34134221
Phys Rev E. 2021 May;103(5):053206. doi: 10.1103/PhysRevE.103.053206.

Using a modified version of the pseudoatom molecular-dynamics approach, the silicon and oxygen equations of state were generated and then employed to construct the equation of state of silicon dioxide. The results are supported by the close agreement with...

A Disease Control-Oriented Land Cover Land Use Map for Myanmar.

Data

Chen D, Shevade V, Baer A, He J, Hoffman-Hall A, Ying Q, Li Y, Loboda TV.
PMID: 34504894
Data (Basel). 2021 Jun;6(6). doi: 10.3390/data6060063. Epub 2021 Jun 13.

Malaria is a serious infectious disease that leads to massive casualties globally. Myanmar is a key battleground for the global fight against malaria because it is where the emergence of drug-resistant malaria parasites has been documented. Controlling the spread...

Santa Ana winds and predictors of wildfire progression in southern California.

International journal of wildland fire

Billmire M, French NHF, Loboda T, Owen RC, Tyner M.
PMID: 34483633
Int J Wildland Fire. 2014;23(8):1119-1129. doi: 10.1071/wf13046. Epub 2014 Nov 18.

Santa Ana winds have been implicated as a major driver of large wildfires in southern California. While numerous anecdotal reports exist, there is little quantitative analysis in peer-reviewed literature on how this weather phenomenon influences fire progression rates. We...

Clinical and Radiological Characteristics of Non-Benign Pineal Cyst Lesions in Children.

Frontiers in neurology

Arkar U, Kučan R, Perković Benedik M, Hostnik T, Vipotnik Vesnaver T, Loboda T, Bošnjak R, Osredkar D.
PMID: 34512533
Front Neurol. 2021 Aug 20;12:722696. doi: 10.3389/fneur.2021.722696. eCollection 2021.

No abstract available.

Dynophore-Based Approach in Virtual Screening: A Case of Human DNA Topoisomerase IIα.

International journal of molecular sciences

Janežič M, Valjavec K, Loboda KB, Herlah B, Ogris I, Kozorog M, Podobnik M, Grdadolnik SG, Wolber G, Perdih A.
PMID: 34948269
Int J Mol Sci. 2021 Dec 15;22(24). doi: 10.3390/ijms222413474.

In this study, we utilized human DNA topoisomerase IIα as a model target to outline a dynophore-based approach to catalytic inhibitor design. Based on MD simulations of a known catalytic inhibitor and the native ATP ligand analog, AMP-PNP, we...

Showing 1 to 12 of 53 entries