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Comparative study of seeding methods for three-dimensional polymeric scaffolds.

Journal of biomedical materials research

Burg KJ, Holder WD, Culberson CR, Beiler RJ, Greene KG, Loebsack AB, Roland WD, Eiselt P, Mooney DJ, Halberstadt CR.
PMID: 11007628
J Biomed Mater Res. 2000 Dec 05;52(3):576. doi: 10.1002/1097-4636(20001205)52:3<576::aid-jbm18>3.0.co;2-c.

No abstract available.

Stereocontrolled enantioselective total synthesis of the [2+2] quadrigemine alkaloids.

Tetrahedron

Canham SM, Hafensteiner BD, Lebsack AD, May-Dracka TL, Nam S, Stearns BA, Overman LE.
PMID: 26257440
Tetrahedron. 2015 Sep 16;71(37):6424-6436. doi: 10.1016/j.tet.2015.02.080.

A unified strategy for enantioselective total synthesis of all stereoisomers of the 2+2 family of quadrigemine alkaloids is reported. In this approach, two enantioselective intramolecular Heck reactions are carried out at the same time on precursors fashioned in four...

Discovery of a Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase with Oral Anti-Inflammatory Activity.

ACS medicinal chemistry letters

Tichenor MS, Wiener JJM, Rao NL, Pooley Deckhut C, Barbay JK, Kreutter KD, Bacani GM, Wei J, Chang L, Murrey HE, Wang W, Ahn K, Huber M, Rex E, Coe KJ, Wu J, Seierstad M, Bembenek SD, Leonard KA, Lebsack AD, Venable JD, Edwards JP.
PMID: 34055226
ACS Med Chem Lett. 2021 Apr 05;12(5):782-790. doi: 10.1021/acsmedchemlett.1c00044. eCollection 2021 May 13.

Bruton's tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase that plays a critical role in the activation of B cells, macrophages, and osteoclasts. Given the key role of these cell types in the pathology of autoimmune disorders, BTK inhibitors...

Showing 1 to 3 of 3 entries