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Showing 1 to 12 of 36 entries
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An HCV-positive recipient of an HCV-positive donor liver successfully treated before and immediately after liver transplant with daclatasvir, sofosbuvir, and ribavirin.

Clinical case reports

Poordad F, Lawitz E, Gutierrez JA, Guerrero J, Speeg K, Swenson ES.
PMID: 28396749
Clin Case Rep. 2017 Feb 03;5(4):371-375. doi: 10.1002/ccr3.841. eCollection 2017 Apr.

This case suggests that initiation of HCV therapy immediately after liver transplantation with well-tolerated, all-oral regimens may achieve a virologic cure in HCV-positive recipients, thus preventing post-transplant HCV recurrence and associated disease progression. This strategy may broaden utilization of...

Expandable Polyaryl-Ether-Ether-Ketone Spacers for Interbody Distraction in the Lumbar Spine.

Global spine journal

Alimi M, Shin B, Macielak M, Hofstetter CP, Njoku I, Tsiouris AJ, Elowitz E, Härtl R.
PMID: 26131383
Global Spine J. 2015 Jun;5(3):169-78. doi: 10.1055/s-0035-1552988.

Study Design Retrospective case series. Objective StaXx XD (Spine Wave, Inc., Shelton, CT, United States) is an expandable polyaryl-ether-ether-ketone (PEEK) wafer implant utilized in the treatment of lumbar degenerative disease. PEEK implants have been successfully used as interbody devices....

EDP-305 in patients with NASH: A phase II double-blind placebo-controlled dose-ranging study.

Journal of hepatology

Ratziu V, Rinella ME, Neuschwander-Tetri BA, Lawitz E, Denham D, Kayali Z, Sheikh A, Kowdley KV, Desta T, Elkhashab M, DeGrauw J, Goodwin B, Ahmad A, Adda N.
PMID: 34740705
J Hepatol. 2021 Nov 02; doi: 10.1016/j.jhep.2021.10.018. Epub 2021 Nov 02.

BACKGROUND & AIMS: EDP-305 is an oral farnesoid X receptor (FXR) agonist under development for treating nonalcoholic steatohepatitis (NASH). The efficacy, safety, and tolerability of EDP-305 was evaluated in a Phase 2, randomized, double-blind, placebo-controlled study.METHODS: Non-cirrhotic patients with...

Chiral motion in colloidal electrophoresis.

Physical review. E

Braverman L, Mowitz A, Witten TA.
PMID: 32688502
Phys Rev E. 2020 Jun;101(6):062608. doi: 10.1103/PhysRevE.101.062608.

Asymmetrically charged, nonspherical colloidal particles in general perform complex rotations and oblique motions under an electric field. The interplay of electrostatic and hydrodynamic forces complicates the prediction of these motions. We demonstrate a method of calculating the body tensors...

Quality improvement and practice-based research in sleep medicine using structured clinical documentation in the electronic medical record.

Sleep science and practice

Maraganore DM, Freedom T, Simon KC, Lovitz LE, Musleh C, Munson R, Nasir N, Patel S, Paul J, Viola-Saltzman M, Meyers S, Chesis R, Hillman L, Tideman S, Pham A, Vazquez RM, Frigerio R.
PMID: 32395635
Sleep Sci Pract. 2020 Jan 02;4:1. doi: 10.1186/s41606-019-0038-2.

BACKGROUND: We developed and implemented a structured clinical documentation support (SCDS) toolkit within the electronic medical record, to optimize patient care, facilitate documentation, and capture data at office visits in a sleep medicine/neurology clinic for patient care and research...

Correction: Serum Wisteria floribunda agglutinin-positive Mac-2-binding protein levels predict the presence of fibrotic nonalcoholic steatohepatitis (NASH) and NASH cirrhosis.

PloS one

Alkhouri N, Johnson C, Adams L, Kitajima S, Tsuruno C, Colpitts TL, Hatcho K, Lawitz E, Lopez R, Feldstein AE.
PMID: 30286196
PLoS One. 2018 Oct 04;13(10):e0205541. doi: 10.1371/journal.pone.0205541. eCollection 2018.

[This corrects the article DOI: 10.1371/journal.pone.0202226.].

Evaluation of pharmacokinetics, user handling, and tolerability of peginterferon alfa-2a (40 kDa) delivered via a disposable autoinjector device.

Patient preference and adherence

Varunok P, Lawitz E, Beavers KL, Matusow G, Leong R, Lambert N, Bernaards C, Solsky J, Brennan BJ, Wat C, Bertasso A.
PMID: 22163158
Patient Prefer Adherence. 2011;5:587-99. doi: 10.2147/PPA.S26566. Epub 2011 Nov 24.

BACKGROUND: Peginterferon alfa-2a (40 kDa) is currently administered using a prefilled syringe. The peginterferon alfa-2a disposable autoinjector is a new safety-engineered device designed to facilitate injection and reduce the risk of needlestick injuries. The analysis of two open-label Phase...

XI. Uncomplicated Fractures of the Tarsal Scaphoid.

Annals of surgery

Horwitz AE.
PMID: 17863083
Ann Surg. 1913 Oct;58(4):526-32. doi: 10.1097/00000658-191310000-00011.

No abstract available.

Simeprevir, daclatasvir, and sofosbuvir for hepatitis C virus-infected patients: Long-term follow-up results from the open-label, Phase II IMPACT study.

Health science reports

Lawitz E, Poordad F, Gutierrez JA, Beumont M, Beets G, Vandevoorde A, Remoortere PV, Luo D, Vijgen L, Eygen VV, Gamil M.
PMID: 32270053
Health Sci Rep. 2020 Feb 22;3(2):e145. doi: 10.1002/hsr2.145. eCollection 2020 Jun.

BACKGROUND AND AIMS: Direct-acting antiviral agents (DAAs) for hepatitis C virus (HCV) infection have resulted in high rates of sustained virologic response (SVR) following 8 to 24 weeks of treatment. However, difficult-to-cure/cirrhotic patients typically require a longer treatment duration...

Predicting tensorial electrophoretic effects in asymmetric colloids.

Physical review. E

Mowitz AJ, Witten TA.
PMID: 29347303
Phys Rev E. 2017 Dec;96(6):062613. doi: 10.1103/PhysRevE.96.062613. Epub 2017 Dec 20.

We formulate a numerical method for predicting the tensorial linear response of a rigid, asymmetrically charged body to an applied electric field. This prediction requires calculating the response of the fluid to the Stokes drag forces on the moving...

Performance of the GHS Mixtures Equation for Predicting Acute Oral Toxicity.

Regulatory toxicology and pharmacology : RTP

Hamm J, Allen D, Ceger P, Flint T, Lowit A, O'Dell L, Tao J, Kleinstreuer N.
PMID: 34298086
Regul Toxicol Pharmacol. 2021 Oct;125:105007. doi: 10.1016/j.yrtph.2021.105007. Epub 2021 Jul 20.

Acute oral toxicity classifications are based on the estimated chemical dose causing lethality in 50 % of laboratory animals tested (LD

Advertising's role in student nurse recruitment.

Hospitals

LOWITZ AC.
PMID: 14880150
Hospitals. 1951 Dec;25(12):44-6.

No abstract available.

Showing 1 to 12 of 36 entries