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Encapsulated cells expressing a chemotherapeutic activating enzyme allow the targeting of subtoxic chemotherapy and are safe and efficacious: data from two clinical trials in pancreatic cancer.

Pharmaceutics

Löhr JM, Haas SL, Kröger JC, Friess HM, Höft R, Goretzki PE, Peschel C, Schweigert M, Salmons B, Gunzburg WH.
PMID: 25116885
Pharmaceutics. 2014 Aug 11;6(3):447-66. doi: 10.3390/pharmaceutics6030447.

Despite progress in the treatment of pancreatic cancer, there is still a need for improved therapies. In this manuscript, we report clinical experience with a new therapy for the treatment of pancreatic cancer involving the implantation of encapsulated cells...

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Löhr JM, Haas SL, Kröger JC, et al. Encapsulated cells expressing a chemotherapeutic activating enzyme allow the targeting of subtoxic chemotherapy and are safe and efficacious: data from two clinical trials in pancreatic cancer. Pharmaceutics. 2014;6(3):447-66doi: 10.3390/pharmaceutics6030447.
Löhr, J. M., Haas, S. L., Kröger, J. C., Friess, H. M., Höft, R., Goretzki, P. E., Peschel, C., Schweigert, M., Salmons, B., & Gunzburg, W. H. (2014). Encapsulated cells expressing a chemotherapeutic activating enzyme allow the targeting of subtoxic chemotherapy and are safe and efficacious: data from two clinical trials in pancreatic cancer. Pharmaceutics, 6(3), 447-66. https://doi.org/10.3390/pharmaceutics6030447
Löhr, J Matthias, et al. "Encapsulated cells expressing a chemotherapeutic activating enzyme allow the targeting of subtoxic chemotherapy and are safe and efficacious: data from two clinical trials in pancreatic cancer." Pharmaceutics vol. 6,3 (2014): 447-66. doi: https://doi.org/10.3390/pharmaceutics6030447
Löhr JM, Haas SL, Kröger JC, Friess HM, Höft R, Goretzki PE, Peschel C, Schweigert M, Salmons B, Gunzburg WH. Encapsulated cells expressing a chemotherapeutic activating enzyme allow the targeting of subtoxic chemotherapy and are safe and efficacious: data from two clinical trials in pancreatic cancer. Pharmaceutics. 2014 Aug 11;6(3):447-66. doi: 10.3390/pharmaceutics6030447. PMID: 25116885; PMCID: PMC4190529.
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"Red-flag" symptom clusters in transthyretin familial amyloid polyneuropathy.

Journal of the peripheral nervous system : JPNS

Conceição I, González-Duarte A, Obici L, Schmidt HH, Simoneau D, Ong ML, Amass L.
PMID: 26663427
J Peripher Nerv Syst. 2016 Mar;21(1):5-9. doi: 10.1111/jns.12153.

Transthyretin familial amyloid polyneuropathy (TTR-FAP) is a rare, progressive, life-threatening, hereditary disorder caused by mutations in the transthyretin gene and characterized by extracellular deposition of transthyretin-derived amyloid fibrils in peripheral and autonomic nerves, heart, and other organs. TTR-FAP is...

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Conceição I, González-Duarte A, Obici L, et al. "Red-flag" symptom clusters in transthyretin familial amyloid polyneuropathy. J Peripher Nerv Syst. 2016;21(1):5-9doi: 10.1111/jns.12153.
Conceição, I., González-Duarte, A., Obici, L., Schmidt, H. H., Simoneau, D., Ong, M. L., & Amass, L. (2016). "Red-flag" symptom clusters in transthyretin familial amyloid polyneuropathy. Journal of the peripheral nervous system : JPNS, 21(1), 5-9. https://doi.org/10.1111/jns.12153
Conceição, Isabel, et al. ""Red-flag" symptom clusters in transthyretin familial amyloid polyneuropathy." Journal of the peripheral nervous system : JPNS vol. 21,1 (2016): 5-9. doi: https://doi.org/10.1111/jns.12153
Conceição I, González-Duarte A, Obici L, Schmidt HH, Simoneau D, Ong ML, Amass L. "Red-flag" symptom clusters in transthyretin familial amyloid polyneuropathy. J Peripher Nerv Syst. 2016 Mar;21(1):5-9. doi: 10.1111/jns.12153. PMID: 26663427; PMCID: PMC4788142.
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Evaluation of a post-processing approach for multiscale analysis of biphasic mechanics of chondrocytes, DOI: 10.1080/10255842.2013.809711.

Computer methods in biomechanics and biomedical engineering

Sibole SC, Maas S, Halloran JP, Weiss JA, Erdemir A.
PMID: 24383709
Comput Methods Biomech Biomed Engin. 2016;19(1):ii. doi: 10.1080/10255842.2013.869043. Epub 2014 Jan 02.

No abstract available.

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Sibole SC, Maas S, Halloran JP, et al. Evaluation of a post-processing approach for multiscale analysis of biphasic mechanics of chondrocytes, DOI: 10.1080/10255842.2013.809711. Comput Methods Biomech Biomed Engin. 2014;19(1):iidoi: 10.1080/10255842.2013.869043.
Sibole, S. C., Maas, S., Halloran, J. P., Weiss, J. A., & Erdemir, A. (2016). Evaluation of a post-processing approach for multiscale analysis of biphasic mechanics of chondrocytes, DOI: 10.1080/10255842.2013.809711. Computer methods in biomechanics and biomedical engineering, 19(1), ii. https://doi.org/10.1080/10255842.2013.869043
Sibole, Scott C, et al. "Evaluation of a post-processing approach for multiscale analysis of biphasic mechanics of chondrocytes, DOI: 10.1080/10255842.2013.809711." Computer methods in biomechanics and biomedical engineering vol. 19,1 (2016): ii. doi: https://doi.org/10.1080/10255842.2013.869043
Sibole SC, Maas S, Halloran JP, Weiss JA, Erdemir A. Evaluation of a post-processing approach for multiscale analysis of biphasic mechanics of chondrocytes, DOI: 10.1080/10255842.2013.809711. Comput Methods Biomech Biomed Engin. 2016;19(1):ii. doi: 10.1080/10255842.2013.869043. Epub 2014 Jan 02. PMID: 24383709.
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Transplantation of tissue-engineered cell sheets for stricture prevention after endoscopic submucosal dissection of the oesophagus.

United European gastroenterology journal

Jonas E, Sjöqvist S, Elbe P, Kanai N, Enger J, Haas SL, Mohkles-Barakat A, Okano T, Takagi R, Ohki T, Yamamoto M, Kondo M, Markland K, Lim ML, Yamato M, Nilsson M, Permert J, Blomberg P, Löhr JM.
PMID: 28408991
United European Gastroenterol J. 2016 Dec;4(6):741-753. doi: 10.1177/2050640616631205. Epub 2016 Feb 19.

BACKGROUND AND OBJECTIVE: Endoscopic mucosal dissection (ESD) is a treatment option for oesophagus tumours localized to the mucosa enabling en bloc removal of large lesions. The resulting larger mucosal defects have resulted in an increase in the occurrence of...

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Jonas E, Sjöqvist S, Elbe P, et al. Transplantation of tissue-engineered cell sheets for stricture prevention after endoscopic submucosal dissection of the oesophagus. United European Gastroenterol J. 2016;4(6):741-753doi: 10.1177/2050640616631205.
Jonas, E., Sjöqvist, S., Elbe, P., Kanai, N., Enger, J., Haas, S. L., Mohkles-Barakat, A., Okano, T., Takagi, R., Ohki, T., Yamamoto, M., Kondo, M., Markland, K., Lim, M. L., Yamato, M., Nilsson, M., Permert, J., Blomberg, P., & Löhr, J. M. (2016). Transplantation of tissue-engineered cell sheets for stricture prevention after endoscopic submucosal dissection of the oesophagus. United European gastroenterology journal, 4(6), 741-753. https://doi.org/10.1177/2050640616631205
Jonas, Eduard, et al. "Transplantation of tissue-engineered cell sheets for stricture prevention after endoscopic submucosal dissection of the oesophagus." United European gastroenterology journal vol. 4,6 (2016): 741-753. doi: https://doi.org/10.1177/2050640616631205
Jonas E, Sjöqvist S, Elbe P, Kanai N, Enger J, Haas SL, Mohkles-Barakat A, Okano T, Takagi R, Ohki T, Yamamoto M, Kondo M, Markland K, Lim ML, Yamato M, Nilsson M, Permert J, Blomberg P, Löhr JM. Transplantation of tissue-engineered cell sheets for stricture prevention after endoscopic submucosal dissection of the oesophagus. United European Gastroenterol J. 2016 Dec;4(6):741-753. doi: 10.1177/2050640616631205. Epub 2016 Feb 19. PMID: 28408991; PMCID: PMC5386228.
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Static and Dynamic Differences in Fixation Stability between a Spacer Plate and a Small Stature Plate Fixator Used for High Tibial Osteotomies: A Biomechanical Bone Composite Study.

ISRN orthopedics

Maas S, Diffo Kaze A, Dueck K, Pape D.
PMID: 24959357
ISRN Orthop. 2013 Sep 23;2013:387620. doi: 10.1155/2013/387620. eCollection 2013.

Background. The objective of the present study was to compare mechanical strength and stability of the newly designed spacer plate with the gold standard plate for the treatment of medial knee joint osteoarthritis. Materials and Methods. Ten fourth-generation tibial...

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Maas S, Diffo Kaze A, Dueck K, et al. Static and Dynamic Differences in Fixation Stability between a Spacer Plate and a Small Stature Plate Fixator Used for High Tibial Osteotomies: A Biomechanical Bone Composite Study. ISRN Orthop. 2013;2013:387620doi: 10.1155/2013/387620.
Maas, S., Diffo Kaze, A., Dueck, K., & Pape, D. (2013). Static and Dynamic Differences in Fixation Stability between a Spacer Plate and a Small Stature Plate Fixator Used for High Tibial Osteotomies: A Biomechanical Bone Composite Study. ISRN orthopedics, 2013387620. https://doi.org/10.1155/2013/387620
Maas, Stefan, et al. "Static and Dynamic Differences in Fixation Stability between a Spacer Plate and a Small Stature Plate Fixator Used for High Tibial Osteotomies: A Biomechanical Bone Composite Study." ISRN orthopedics vol. 2013 (2013): 387620. doi: https://doi.org/10.1155/2013/387620
Maas S, Diffo Kaze A, Dueck K, Pape D. Static and Dynamic Differences in Fixation Stability between a Spacer Plate and a Small Stature Plate Fixator Used for High Tibial Osteotomies: A Biomechanical Bone Composite Study. ISRN Orthop. 2013 Sep 23;2013:387620. doi: 10.1155/2013/387620. eCollection 2013. PMID: 24959357; PMCID: PMC4045360.
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Sequence-specific Priming and Exonuclease-released Fluorescence Assay for Rapid and Reliable HLA-A Molecular Typing.

Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology

Menon R, Rudert WA, Braun ER, Jaquins-Gerstl A, Faas SJ, Trucco M.
PMID: 10462597
Mol Diagn. 1997 Jun;2(2):99-111. doi: 10.1054/MODI00200099.

Background: The rapid and sensitive method described for low-resolution DNA typing of alleles at the HLA-A locus is based on a sequence-specific primer polymerase chain reaction approach that eliminates post-polymerase chain reaction gel electrophoresis to analyze the results. Methods...

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Menon R, Rudert WA, Braun ER, et al. Sequence-specific Priming and Exonuclease-released Fluorescence Assay for Rapid and Reliable HLA-A Molecular Typing. Mol Diagn. 1997;2(2):99-111doi: 10.1054/MODI00200099.
Menon, R., Rudert, W. A., Braun, E. R., Jaquins-Gerstl, A., Faas, S. J., & Trucco, M. (1997). Sequence-specific Priming and Exonuclease-released Fluorescence Assay for Rapid and Reliable HLA-A Molecular Typing. Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology, 2(2), 99-111. https://doi.org/10.1054/MODI00200099
Menon, et al. "Sequence-specific Priming and Exonuclease-released Fluorescence Assay for Rapid and Reliable HLA-A Molecular Typing." Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology vol. 2,2 (1997): 99-111. doi: https://doi.org/10.1054/MODI00200099
Menon R, Rudert WA, Braun ER, Jaquins-Gerstl A, Faas SJ, Trucco M. Sequence-specific Priming and Exonuclease-released Fluorescence Assay for Rapid and Reliable HLA-A Molecular Typing. Mol Diagn. 1997 Jun;2(2):99-111. doi: 10.1054/MODI00200099. PMID: 10462597.
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From the Art Director's Desk.

Neuro endocrinology letters

Maas L.
PMID: 11455323
Neuro Endocrinol Lett. 2000;21(1):4.

No abstract available.

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Maas L. From the Art Director's Desk. Neuro Endocrinol Lett. 2000;21(1):4
Maas, L. (2000). From the Art Director's Desk. Neuro endocrinology letters, 21(1), 4.
Maas, Lili. "From the Art Director's Desk." Neuro endocrinology letters vol. 21,1 (2000): 4.
Maas L. From the Art Director's Desk. Neuro Endocrinol Lett. 2000;21(1):4. PMID: 11455323.
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Preparing clinical-grade myeloid dendritic cells by electroporation-mediated transfection of in vitro amplified tumor-derived mRNA and safety testing in stage IV malignant melanoma.

Journal of translational medicine

Markovic SN, Dietz AB, Greiner CW, Maas ML, Butler GW, Padley DJ, Bulur PA, Allred JB, Creagan ET, Ingle JN, Gastineau DA, Vuk-Pavlovic S.
PMID: 16911798
J Transl Med. 2006 Aug 15;4:35. doi: 10.1186/1479-5876-4-35.

BACKGROUND: Dendritic cells (DCs) have been used as vaccines in clinical trials of immunotherapy of cancer and other diseases. Nonetheless, progress towards the use of DCs in the clinic has been slow due in part to the absence of...

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Markovic SN, Dietz AB, Greiner CW, et al. Preparing clinical-grade myeloid dendritic cells by electroporation-mediated transfection of in vitro amplified tumor-derived mRNA and safety testing in stage IV malignant melanoma. J Transl Med. 2006;4:35doi: 10.1186/1479-5876-4-35.
Markovic, S. N., Dietz, A. B., Greiner, C. W., Maas, M. L., Butler, G. W., Padley, D. J., Bulur, P. A., Allred, J. B., Creagan, E. T., Ingle, J. N., Gastineau, D. A., & Vuk-Pavlovic, S. (2006). Preparing clinical-grade myeloid dendritic cells by electroporation-mediated transfection of in vitro amplified tumor-derived mRNA and safety testing in stage IV malignant melanoma. Journal of translational medicine, 435. https://doi.org/10.1186/1479-5876-4-35
Markovic, Svetomir N, et al. "Preparing clinical-grade myeloid dendritic cells by electroporation-mediated transfection of in vitro amplified tumor-derived mRNA and safety testing in stage IV malignant melanoma." Journal of translational medicine vol. 4 (2006): 35. doi: https://doi.org/10.1186/1479-5876-4-35
Markovic SN, Dietz AB, Greiner CW, Maas ML, Butler GW, Padley DJ, Bulur PA, Allred JB, Creagan ET, Ingle JN, Gastineau DA, Vuk-Pavlovic S. Preparing clinical-grade myeloid dendritic cells by electroporation-mediated transfection of in vitro amplified tumor-derived mRNA and safety testing in stage IV malignant melanoma. J Transl Med. 2006 Aug 15;4:35. doi: 10.1186/1479-5876-4-35. PMID: 16911798; PMCID: PMC1570143.
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Variable time lag and backward ejection in full-dimensional analysis of strong-field double ionization.

Physical review letters

Haan SL, Breen L, Karim A, Eberly JH.
PMID: 17025816
Phys Rev Lett. 2006 Sep 08;97(10):103008. doi: 10.1103/PhysRevLett.97.103008. Epub 2006 Sep 08.

Ensembles of 400,000 two-electron trajectories in three space dimensions are used with Newtonian equations of motion to track atomic double ionization under very strong laser fields. We report a variable time lag between e-e collision and double ionization, and...

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Haan SL, Breen L, Karim A, et al. Variable time lag and backward ejection in full-dimensional analysis of strong-field double ionization. Phys Rev Lett. 2006;97(10):103008doi: 10.1103/PhysRevLett.97.103008.
Haan, S. L., Breen, L., Karim, A., & Eberly, J. H. (2006). Variable time lag and backward ejection in full-dimensional analysis of strong-field double ionization. Physical review letters, 97(10), 103008. https://doi.org/10.1103/PhysRevLett.97.103008
Haan, S L, et al. "Variable time lag and backward ejection in full-dimensional analysis of strong-field double ionization." Physical review letters vol. 97,10 (2006): 103008. doi: https://doi.org/10.1103/PhysRevLett.97.103008
Haan SL, Breen L, Karim A, Eberly JH. Variable time lag and backward ejection in full-dimensional analysis of strong-field double ionization. Phys Rev Lett. 2006 Sep 08;97(10):103008. doi: 10.1103/PhysRevLett.97.103008. Epub 2006 Sep 08. PMID: 17025816.
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MUTATION INDUCTION AND EXPRESSION IN BACTERIA.

Proceedings of the National Academy of Sciences of the United States of America

Haas FL, Doudney CO.
PMID: 16590554
Proc Natl Acad Sci U S A. 1959 Nov;45(11):1620-4. doi: 10.1073/pnas.45.11.1620.

No abstract available.

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Haas FL, Doudney CO. MUTATION INDUCTION AND EXPRESSION IN BACTERIA. Proc Natl Acad Sci U S A. 1959;45(11):1620-4doi: 10.1073/pnas.45.11.1620.
Haas, F. L., & Doudney, C. O. (1959). MUTATION INDUCTION AND EXPRESSION IN BACTERIA. Proceedings of the National Academy of Sciences of the United States of America, 45(11), 1620-4. https://doi.org/10.1073/pnas.45.11.1620
Haas, F L, and Doudney, C O. "MUTATION INDUCTION AND EXPRESSION IN BACTERIA." Proceedings of the National Academy of Sciences of the United States of America vol. 45,11 (1959): 1620-4. doi: https://doi.org/10.1073/pnas.45.11.1620
Haas FL, Doudney CO. MUTATION INDUCTION AND EXPRESSION IN BACTERIA. Proc Natl Acad Sci U S A. 1959 Nov;45(11):1620-4. doi: 10.1073/pnas.45.11.1620. PMID: 16590554; PMCID: PMC222770.
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Nonsequential double ionization as a completely classical photoelectric effect.

Physical review letters

Ho PJ, Panfili R, Haan SL, Eberly JH.
PMID: 15783962
Phys Rev Lett. 2005 Mar 11;94(9):093002. doi: 10.1103/PhysRevLett.94.093002. Epub 2005 Mar 09.

We introduce a unified and simplified theory of atomic double ionization. Our results show that at high laser intensities (I>/=10(14) W/cm(2)) purely classical correlation is strong enough to account for all of the main features observed in experiments to...

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Ho PJ, Panfili R, Haan SL, et al. Nonsequential double ionization as a completely classical photoelectric effect. Phys Rev Lett. 2005;94(9):093002doi: 10.1103/PhysRevLett.94.093002.
Ho, P. J., Panfili, R., Haan, S. L., & Eberly, J. H. (2005). Nonsequential double ionization as a completely classical photoelectric effect. Physical review letters, 94(9), 093002. https://doi.org/10.1103/PhysRevLett.94.093002
Ho, Phay J, et al. "Nonsequential double ionization as a completely classical photoelectric effect." Physical review letters vol. 94,9 (2005): 093002. doi: https://doi.org/10.1103/PhysRevLett.94.093002
Ho PJ, Panfili R, Haan SL, Eberly JH. Nonsequential double ionization as a completely classical photoelectric effect. Phys Rev Lett. 2005 Mar 11;94(9):093002. doi: 10.1103/PhysRevLett.94.093002. Epub 2005 Mar 09. PMID: 15783962.
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An unusual case of hemosiderotic fibrohistiocytic lipomatous lesion: correlation of MRI and pathologic findings.

Sarcoma

de Vreeze RS, Koops W, Haas RL, van Coevorden F.
PMID: 18584051
Sarcoma. 2008;2008:893918. doi: 10.1155/2008/893918.

The spectrum of lipomatous lesions ranges from benign to highly malignant disease. Differentiation between these lesions is important to indicate prognosis and choose the most appropriate treatment. Hemosiderotic fibrohistiocytic lipomatous lesion (HFLL) is a rare subtype of lipomatous tumor....

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de Vreeze RS, Koops W, Haas RL, et al. An unusual case of hemosiderotic fibrohistiocytic lipomatous lesion: correlation of MRI and pathologic findings. Sarcoma. 2008;2008:893918doi: 10.1155/2008/893918.
de Vreeze, R. S., Koops, W., Haas, R. L., & van Coevorden, F. (2008). An unusual case of hemosiderotic fibrohistiocytic lipomatous lesion: correlation of MRI and pathologic findings. Sarcoma, 2008893918. https://doi.org/10.1155/2008/893918
de Vreeze, Ronald S A, et al. "An unusual case of hemosiderotic fibrohistiocytic lipomatous lesion: correlation of MRI and pathologic findings." Sarcoma vol. 2008 (2008): 893918. doi: https://doi.org/10.1155/2008/893918
de Vreeze RS, Koops W, Haas RL, van Coevorden F. An unusual case of hemosiderotic fibrohistiocytic lipomatous lesion: correlation of MRI and pathologic findings. Sarcoma. 2008;2008:893918. doi: 10.1155/2008/893918. PMID: 18584051; PMCID: PMC2435605.
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