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Showing 1 to 12 of 20 entries
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Invasion of Ureaplasma diversum in bovine spermatozoids.

BMC research notes

Buzinhani M, Yamaguti M, Oliveira RC, Cortez BA, Marques LM, Machado-Santelli GM, Assumpção ME, Timenetsky J.
PMID: 22032232
BMC Res Notes. 2011 Oct 27;4:455. doi: 10.1186/1756-0500-4-455.

BACKGROUND: Ureaplasma diversum has been associated with infertility in cows. In bulls, this mollicute colonizes the prepuce and distal portion of the urethra and may infect sperm cells. The aim of this study is to analyze in vitro interaction...

Toxicity of spike fragments SARS-CoV-2 S protein for zebrafish: A tool to study its hazardous for human health?.

The Science of the total environment

Ventura Fernandes BH, Feitosa NM, Barbosa AP, Bomfim CG, Garnique AMB, Rosa IF, Rodrigues MS, Doretto LB, Costa DF, Santos BC, Franco GA, Neto JF, Lunardi JS, Bellot MS, Alves NPC, Costa CC, Aracati MF, Rodrigues LF, Costa CC, Cirilo RH, Colagrande RM, Gomes FIF, Nakajima RT, Belo MAA, Giaquinto PC, de Oliveira SL, Eto SF, Fernandes DC, Manrique WG, Conde G, Rosales RRC, Todeschini I, Rivero I, Llontop E, Sgro GG, Oka GU, Bueno NF, Ferraris FK, de Magalhães MTQ, Medeiros RJ, Gomes JMM, Junqueira MS, Conceição K, Pontes LG, Neto AC, Perez AC, Barcellos LG, Júnior JDC, Dorlass EG, Camara NOS, Durigon EL, Cunha FQ, Nóbrega RH, Machado-Santelli GM, Farah CS, Veras FP, Galindo-Villegas J, Costa-Lotufo LV, Cunha TM, Chammas R, Carvalho LR, Guzzo CR, Malafaia G, Charlie-Silva I.
PMID: 34942250
Sci Total Environ. 2021 Dec 20;152345. doi: 10.1016/j.scitotenv.2021.152345. Epub 2021 Dec 20.

Despite the significant increase in the generation of SARS-CoV-2 contaminated domestic and hospital wastewater, little is known about the ecotoxicological effects of the virus or its structural components in freshwater vertebrates. In this context, this study evaluated the deleterious...

Toxicity of spike fragments SARS-CoV-2 S protein for zebrafish: A tool to study its hazardous for human health?.

The Science of the total environment

Ventura Fernandes BH, Feitosa NM, Barbosa AP, Bomfim CG, Garnique AMB, Rosa IF, Rodrigues MS, Doretto LB, Costa DF, Camargo-Dos-Santos B, Franco GA, Neto JF, Lunardi JS, Bellot MS, Alves NPC, Costa CC, Aracati MF, Rodrigues LF, Costa CC, Cirilo RH, Colagrande RM, Gomes FIF, Nakajima RT, Belo MAA, Giaquinto PC, de Oliveira SL, Eto SF, Fernandes DC, Manrique WG, Conde G, Rosales RRC, Todeschini I, Rivero I, Llontop E, Sgro GG, Oka GU, Bueno NF, Ferraris FK, de Magalhães MTQ, Medeiros RJ, Mendonça-Gomes JM, Junqueira MS, Conceição K, Pontes LG, Condino-Neto A, Perez AC, Barcellos LJG, Júnior JDC, Dorlass EG, Camara NOS, Durigon EL, Cunha FQ, Nóbrega RH, Machado-Santelli GM, Farah CS, Veras FP, Galindo-Villegas J, Costa-Lotufo LV, Cunha TM, Chammas R, Carvalho LR, Guzzo CR, Malafaia G, Charlie-Silva I.
PMID: 34942250
Sci Total Environ. 2021 Dec 21;813:152345. doi: 10.1016/j.scitotenv.2021.152345. Epub 2021 Dec 21.

Despite the significant increase in the generation of SARS-CoV-2 contaminated domestic and hospital wastewater, little is known about the ecotoxicological effects of the virus or its structural components in freshwater vertebrates. In this context, this study evaluated the deleterious...

The histone genes cluster in Rhynchosciara americana and its transcription profile in salivary glands during larval development.

Genetics and molecular biology

Siviero F, Rezende-Teixeira P, Andrade A, Santelli RV, Machado-Santelli GM.
PMID: 27727361
Genet Mol Biol. 2016 Oct-Dec;39(4):580-588. doi: 10.1590/1678-4685-GMB-2015-0306. Epub 2016 Oct 10.

In this work we report the characterization of the Rhynchosciara americana histone genes cluster nucleotide sequence. It spans 5,131 bp and contains the four core histones and the linker histone H1. Putative control elements were detected. We also determined...

Three-dimensional cell culture for the study of nasal polyps.

Brazilian journal of otorhinolaryngology

França CN, Bachi ALL, Kosugi EM, Pezato R, Machado Santelli GM, Amaral JBD.
PMID: 34924329
Braz J Otorhinolaryngol. 2021 Nov 26; doi: 10.1016/j.bjorl.2021.11.001. Epub 2021 Nov 26.

OBJECTIVES: Three-dimensional (3D) cell cultures have many applications such as stem cell biology research, new drug discovery, cancer, and Chronic Rhinosinusitis with Nasal Polyps (CRSwNP). This disease is characterized by a significant impact on quality of life and productivity....

Toxicity of spike fragments SARS-CoV-2 S protein for zebrafish: A tool to study its hazardous for human health?.

The Science of the total environment

Ventura Fernandes BH, Feitosa NM, Barbosa AP, Bomfim CG, Garnique AMB, Rosa IF, Rodrigues MS, Doretto LB, Costa DF, Camargo-Dos-Santos B, Franco GA, Neto JF, Lunardi JS, Bellot MS, Alves NPC, Costa CC, Aracati MF, Rodrigues LF, Costa CC, Cirilo RH, Colagrande RM, Gomes FIF, Nakajima RT, Belo MAA, Giaquinto PC, de Oliveira SL, Eto SF, Fernandes DC, Manrique WG, Conde G, Rosales RRC, Todeschini I, Rivero I, Llontop E, Sgro GG, Oka GU, Bueno NF, Ferraris FK, de Magalhães MTQ, Medeiros RJ, Mendonça-Gomes JM, Junqueira MS, Conceição K, Pontes LG, Condino-Neto A, Perez AC, Barcellos LJG, Júnior JDC, Dorlass EG, Camara NOS, Durigon EL, Cunha FQ, Nóbrega RH, Machado-Santelli GM, Farah CS, Veras FP, Galindo-Villegas J, Costa-Lotufo LV, Cunha TM, Chammas R, Carvalho LR, Guzzo CR, Malafaia G, Charlie-Silva I.
PMID: 34942250
Sci Total Environ. 2021 Dec 21;813:152345. doi: 10.1016/j.scitotenv.2021.152345. Epub 2021 Dec 21.

Despite the significant increase in the generation of SARS-CoV-2 contaminated domestic and hospital wastewater, little is known about the ecotoxicological effects of the virus or its structural components in freshwater vertebrates. In this context, this study evaluated the deleterious...

Toxicity of spike fragments SARS-CoV-2 S protein for zebrafish: A tool to study its hazardous for human health?.

The Science of the total environment

Ventura Fernandes BH, Feitosa NM, Barbosa AP, Bomfim CG, Garnique AMB, Rosa IF, Rodrigues MS, Doretto LB, Costa DF, Camargo-Dos-Santos B, Franco GA, Neto JF, Lunardi JS, Bellot MS, Alves NPC, Costa CC, Aracati MF, Rodrigues LF, Costa CC, Cirilo RH, Colagrande RM, Gomes FIF, Nakajima RT, Belo MAA, Giaquinto PC, de Oliveira SL, Eto SF, Fernandes DC, Manrique WG, Conde G, Rosales RRC, Todeschini I, Rivero I, Llontop E, Sgro GG, Oka GU, Bueno NF, Ferraris FK, de Magalhães MTQ, Medeiros RJ, Mendonça-Gomes JM, Junqueira MS, Conceição K, Pontes LG, Condino-Neto A, Perez AC, Barcellos LJG, Júnior JDC, Dorlass EG, Camara NOS, Durigon EL, Cunha FQ, Nóbrega RH, Machado-Santelli GM, Farah CS, Veras FP, Galindo-Villegas J, Costa-Lotufo LV, Cunha TM, Chammas R, Carvalho LR, Guzzo CR, Malafaia G, Charlie-Silva I.
PMID: 34942250
Sci Total Environ. 2021 Dec 21;813:152345. doi: 10.1016/j.scitotenv.2021.152345. Epub 2021 Dec 21.

Despite the significant increase in the generation of SARS-CoV-2 contaminated domestic and hospital wastewater, little is known about the ecotoxicological effects of the virus or its structural components in freshwater vertebrates. In this context, this study evaluated the deleterious...

Frontiers in microbiology

Santos-Junior MN, Rezende IS, Souza CLS, Barbosa MS, Campos GB, Brito LF, Queiroz ÉC, Barbosa EN, Teixeira MM, Da Silva LO, Silva LSC, Nascimento FS, Da Silva TL, Martens AA, Siqueira AFP, Assumpção MEOD, Machado-Santelli GM, Bastos BL, Guimarães AMS, Timenetsky J, Marques LM.
PMID: 30050519
Front Microbiol. 2018 Jul 12;9:1538. doi: 10.3389/fmicb.2018.01538. eCollection 2018.

No abstract available.

Exogenous Cx43 expression decrease cell proliferation rate in rat hepatocarcinoma cells independently of functional gap junction.

Cancer cell international

Ionta M, Ferreira RA, Pfister SC, Machado-Santelli GM.
PMID: 19678939
Cancer Cell Int. 2009 Aug 13;9:22. doi: 10.1186/1475-2867-9-22.

BACKGROUND: Gap junction intercellular communication (GJIC) is considered to play a role in the regulation of homeostasis because it regulates important processes, such as cell proliferation and cell differentiation. A reduced or lost GJIC capacity has been observed in...

Independent of ErbB1 gene copy number, EGF stimulates migration but is not associated with cell proliferation in non-small cell lung cancer.

Cancer cell international

Lauand C, Rezende-Teixeira P, Cortez BA, Niero EL, Machado-Santelli GM.
PMID: 23631593
Cancer Cell Int. 2013 Apr 30;13(1):38. doi: 10.1186/1475-2867-13-38.

BACKGROUND: Lung cancer often exhibits molecular changes, such as the overexpression of the ErbB1 gene. ErbB1 encodes epidermal growth factor receptor (EGFR), a tyrosine kinase receptor, involved mainly in cell proliferation and survival. EGFR overexpression has been associated with...

Advances in the integration of optical and mass spectrometry molecular imaging technologies: from omics data to molecular signature discovery.

Discovery medicine

Belizário JE, Sangiuliano BA, Perez-Sosa M, Santos BV, Machado-Santelli G.
PMID: 26760983
Discov Med. 2015 Dec;20(112):393-401.

Many molecular mechanisms in complex biological processes of diseases cannot be fully understood without direct visualization. In the last decades, advances in imaging principles and technologies have expanded our ability to capture and analyze the morphology of tissues and...

Targeting the Oncogenic TBX2 Transcription Factor With Chromomycins.

Frontiers in chemistry

Sahm BDB, Peres J, Rezende-Teixeira P, Santos EA, Branco PC, Bauermeister A, Kimani S, Moreira EA, Bisi-Alves R, Bellis C, Mlaza M, Jimenez PC, Lopes NP, Machado-Santelli GM, Prince S, Costa-Lotufo LV.
PMID: 32195221
Front Chem. 2020 Mar 03;8:110. doi: 10.3389/fchem.2020.00110. eCollection 2020.

The TBX2 transcription factor plays critical roles during embryonic development and it is overexpressed in several cancers, where it contributes to key oncogenic processes including the promotion of proliferation and bypass of senescence. Importantly, based on compelling biological evidences,...

Showing 1 to 12 of 20 entries