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Showing 1 to 12 of 14 entries
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Paradoxical neutrophilic dermatosis induced by biologics and immunosuppressive drugs: A systematic review.

Journal of the American Academy of Dermatology

Haber R, Dib N, El Gemayel M, Makhlouf M.
PMID: 33607180
J Am Acad Dermatol. 2021 Oct;85(4):1048-1049. doi: 10.1016/j.jaad.2021.02.035. Epub 2021 Feb 17.

No abstract available.

Congenital iRHOM2 deficiency causes ADAM17 dysfunction and environmentally directed immunodysregulatory disease.

Nature immunology

Kubo S, Fritz JM, Raquer-McKay HM, Kataria R, Vujkovic-Cvijin I, Al-Shaibi A, Yao Y, Zheng L, Zou J, Waldman AD, Jing X, Farley TK, Park AY, Oler AJ, Charles AK, Makhlouf M, AbouMoussa EH, Hasnah R, Saraiva LR, Ganesan S, Al-Subaiey AA, Matthews H, Flano E, Lee HH, Freeman AF, Sefer AP, Sayar E, Çakır E, Karakoc-Aydiner E, Baris S, Belkaid Y, Ozen A, Lo B, Lenardo MJ.
PMID: 34937930
Nat Immunol. 2022 Jan;23(1):75-85. doi: 10.1038/s41590-021-01093-y. Epub 2021 Dec 22.

We report a pleiotropic disease due to loss-of-function mutations in RHBDF2, the gene encoding iRHOM2, in two kindreds with recurrent infections in different organs. One patient had recurrent pneumonia but no colon involvement, another had recurrent infectious hemorrhagic colitis...

Role of genetic polymorphisms in factor H and MBL genes in Tunisian patients with immunoglobulin A nephropathy.

International journal of nephrology and renovascular disease

Gorgi Y, Hbibi I, Sfar I, Gargueh T, Cherif M, Goucha Louzir R, Daghbouj R, Aouadi H, Makhlouf M, Ben Romdhane T, Jendoubi-Ayed S, Amri M, Kheder A, Lakhoua MR, Ben Abdallah T, Ayed K.
PMID: 21694925
Int J Nephrol Renovasc Dis. 2010;3:27-32. doi: 10.2147/ijnrd.s8442. Epub 2010 Mar 30.

The molecular mechanisms of IgA nephropathy (IgAN) remain poorly understood. Several different polymorphic genes have been investigated in order to demonstrate their possible association with this disease. It is evident that mainly alternative and lectin pathways complement activation and...

Herniated gravid uterus growing in an incisional hernia: study of three cases.

Hernia : the journal of hernias and abdominal wall surgery

Hcini N, Chelli D, Boudaya F, Amraoui J, Makhlouf M, Sfar E.
PMID: 25112381
Hernia. 2016 Aug;20(4):633-6. doi: 10.1007/s10029-014-1291-z. Epub 2014 Aug 12.

No abstract available.

Deconstructing the mouse olfactory percept through an ethological atlas.

Current biology : CB

Manoel D, Makhlouf M, Arayata CJ, Sathappan A, Da'as S, Abdelrahman D, Selvaraj S, Hasnah R, Mainland JD, Gerkin RC, Saraiva LR.
PMID: 33957076
Curr Biol. 2021 Jul 12;31(13):2809-2818.e3. doi: 10.1016/j.cub.2021.04.020. Epub 2021 May 05.

Odor perception in non-humans is poorly understood. Here, we generated the most comprehensive mouse olfactory ethological atlas to date, consisting of behavioral responses to a diverse panel of 73 odorants, including 12 at multiple concentrations. These data revealed that...

Congenital iRHOM2 deficiency causes ADAM17 dysfunction and environmentally directed immunodysregulatory disease.

Nature immunology

Kubo S, Fritz JM, Raquer-McKay HM, Kataria R, Vujkovic-Cvijin I, Al-Shaibi A, Yao Y, Zheng L, Zou J, Waldman AD, Jing X, Farley TK, Park AY, Oler AJ, Charles AK, Makhlouf M, AbouMoussa EH, Hasnah R, Saraiva LR, Ganesan S, Al-Subaiey AA, Matthews H, Flano E, Lee HH, Freeman AF, Sefer AP, Sayar E, Çakır E, Karakoc-Aydiner E, Baris S, Belkaid Y, Ozen A, Lo B, Lenardo MJ.
PMID: 34937930
Nat Immunol. 2022 Jan;23(1):75-85. doi: 10.1038/s41590-021-01093-y. Epub 2021 Dec 22.

We report a pleiotropic disease due to loss-of-function mutations in RHBDF2, the gene encoding iRHOM2, in two kindreds with recurrent infections in different organs. One patient had recurrent pneumonia but no colon involvement, another had recurrent infectious hemorrhagic colitis...

Acute abdominal syndrome revealing an intestinal amoebiasis: Report of two cases in Tunisia.

International journal of surgery case reports

Hamdi G, Zaghdoudi A, Frikha MT, Makhlouf M, Sassi K, Ben Badr M, Ben Slima M.
PMID: 33757264
Int J Surg Case Rep. 2021 Feb;79:466-469. doi: 10.1016/j.ijscr.2021.01.068. Epub 2021 Jan 20.

Amoebiasis is a parasitosis, mainly caused by Entamoeba histolytica (E. histolytica). It is a common disease in tropical and subtropical regions. E. histolytica possesses different mechanisms of pathogenicity, and might lead to the invasion and lysis of the intestinal...

Atypical hemolytic uremic syndrome and mutation analysis of factor H gene in two Tunisian families.

International journal of nephrology and renovascular disease

Habibi I, Sfar I, Ben Alaya W, Methlouthi J, Ayadi A, Brahim M, Blouin J, Dhagbouj R, Ben Rhomdhane T, Makhlouf M, Aouadi H, Ayed-Jendoubi S, Fremeaux-Bacchi V, Sfar T, Ben Abdallah T, Ayed K, Gorgi Y.
PMID: 21694933
Int J Nephrol Renovasc Dis. 2010;3:85-92. doi: 10.2147/ijnrd.s8373. Epub 2010 Jul 01.

We carried out a protein and genetic investigation of the factor H gene mutations within two families presenting with a diagnostic suspicion of atypical hemolytic uremic syndrome (aHUS). The results within the patients of the first family revealed a...

Amniotic Sac Herniation Through a Prior Cornual Scar in The Third Trimester.

AJP reports

Saad AF, Costantine MM, Saade G, Makhlouf M.
PMID: 26495171
AJP Rep. 2015 Oct;5(2):e132-5. doi: 10.1055/s-0035-1549296. Epub 2015 Apr 27.

Introduction Uterine rupture occurs in less than 0.1% of pregnancies. This complication can be detrimental to mother and fetus if not detected and managed in a timely manner. We report an unusual presentation of uterine scar rupture that was...

Can pelvic floor dysfunction after vaginal birth be prevented?.

International urogynecology journal

Howard D, Makhlouf M.
PMID: 27525694
Int Urogynecol J. 2016 Dec;27(12):1811-1815. doi: 10.1007/s00192-016-3117-2. Epub 2016 Aug 15.

INTRODUCTION AND HYPOTHESIS: Significant breakthroughs in our understanding of pelvic floor dysfunction have occurred in the past two decades. The next step is to translate this understanding into effective preventative and early intervention strategies to minimize maternal morbidity from...

Comparison of HLA Class I and II Molecular and Serological Typing within Clinical Laboratory.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia

Ayed K, Jendoubi SA, Makhlouf M, Sfar I, Abdallah TB.
PMID: 17657088
Saudi J Kidney Dis Transpl. 2003 Jan-Mar;14(1):39-42.

In order to develop an adequate tissue typing strategy, we performed human leukocyte antigen (HLA)-A, B and DR generic typing on 235 (120 HLA-A, B and 115 HLA-DR) routine clinical samples by polymerase -chain reaction (PCR)-SSP in parallel with...

Vascular endothelial growth factor genetic polymorphisms and susceptibility to age-related macular degeneration in Tunisian population.

Biomarker research

Habibi I, Sfar I, Chebil A, Kort F, Bouraoui R, Jendoubi-Ayed S, Makhlouf M, Abdallah TB, El Matri L, Gorgi Y.
PMID: 25165559
Biomark Res. 2014 Aug 18;2:15. doi: 10.1186/2050-7771-2-15. eCollection 2014.

PURPOSE: Three VEGF SNPs (-2578) C/A, (+405) G/C and (+936) C/T were investigated in Tunisian exudative AMD patients in order to determine their association with the disease susceptibility and their influence to intravitreal bevacizumab therapy response.METHODS: 145 AMD patients...

Showing 1 to 12 of 14 entries