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Showing 1 to 12 of 127 entries
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Immunity and inflammatory signaling in alcoholic liver disease.

Hepatology international

Mandrekar P, Ambade A, Wen ZA, Zhao Y.
PMID: 26201323
Hepatol Int. 2014 Sep;8:439-46. doi: 10.1007/s12072-014-9518-8. Epub 2014 Mar 28.

The pathogenesis of alcoholic liver disease (ALD) is multifactorial and characterized by steatosis, steatohepatitis and cirrhosis. Several signaling pathways in different liver cell types that contribute to the development and progression of alcoholic liver injury have been identified. Among...

Fungal Histidine Phosphotransferase Plays a Crucial Role in Photomorphogenesis and Pathogenesis in .

Frontiers in chemistry

Mohanan VC, Chandarana PM, Chattoo BB, Patkar RN, Manjrekar J.
PMID: 28580356
Front Chem. 2017 May 19;5:31. doi: 10.3389/fchem.2017.00031. eCollection 2017.

Two-component signal transduction (TCST) pathways play crucial roles in many cellular functions such as stress responses, biofilm formation, and sporulation. The histidine phosphotransferase (HPt), which is an intermediate phosphotransfer protein in a two-component system, transfers a phosphate group to...

Neuroradiologic manifestations of Erdheim-Chester disease.

Neurology. Clinical practice

Parks NE, Goyal G, Go RS, Mandrekar J, Tobin WO.
PMID: 29517068
Neurol Clin Pract. 2018 Feb;8(1):15-20. doi: 10.1212/CPJ.0000000000000422.

BACKGROUND: We describe the neuroradiologic features of a cohort of patients with Erdheim-Chester disease.METHODS: We assessed patients at Mayo Clinic Rochester between January 1, 1990, and July 31, 2016, with pathologically confirmed Erdheim-Chester disease (n = 53).RESULTS: Neuroimaging, including...

Time to progression ratio: promising new metric or just another metric?.

Annals of translational medicine

An MW, Mandrekar SJ.
PMID: 27868011
Ann Transl Med. 2016 Oct;4:S43. doi: 10.21037/atm.2016.10.21.

No abstract available.

Unmasking the Role of Uptake Transporters for Digoxin Uptake Across the Barriers of the Central Nervous System in Rat.

Journal of central nervous system disease

Taskar KS, Mariappan TT, Kurawattimath V, Singh Gautam S, Radhakrishna Mullapudi TV, Sridhar SK, Kallem RR, Marathe P, Mandlekar S.
PMID: 28469522
J Cent Nerv Syst Dis. 2017 Mar 15;9:1179573517693596. doi: 10.1177/1179573517693596. eCollection 2017.

The role of uptake transporter (organic anion-transporting polypeptide [Oatp]) in the disposition of a P-glycoprotein (P-gp) substrate (digoxin) at the barriers of central nervous system, namely, the blood-brain barrier (BBB), blood-spinal cord barrier (BSCB), and brain-cerebrospinal fluid barrier (BCSFB),...

A comparison of clinical teaching evaluations by resident and peer physicians.

Medical teacher

Beckman TJ, Lee MC, Mandrekar JN.
PMID: 15203844
Med Teach. 2004 Jun;26(4):321-5. doi: 10.1080/01421590410001678984.

The purpose of this study was to compare the reliability of inpatient teaching evaluations by resident and peer physicians on Mayo internal medicine hospital services. Three resident and three peer evaluators observed 10 consecutively chosen attending physicians on the...

Hyperferritinemia in pulmonary tuberculosis.

Indian journal of clinical biochemistry : IJCB

D'Souza B, Sinha S, Manjrekar P, D'Souza V.
PMID: 24426230
Indian J Clin Biochem. 2013 Jul;28(3):309-10. doi: 10.1007/s12291-012-0289-5. Epub 2012 Dec 15.

High ferritin levels have been found to be associated with non infectious as well as infectious causes including tuberculosis. This is one case report of 41 year old male who presented with cough with expectoration. The patient had Multi...

Advancing hepatology research: Excellence in open access.

Hepatology communications

Mandrekar P.
PMID: 29404446
Hepatol Commun. 2017 Apr 06;1(2):83. doi: 10.1002/hep4.1034. eCollection 2017 Apr.

No abstract available.

Use of a Conformational-Switching Mechanism to Modulate Exposed Polarity: Discovery of CCR2 Antagonist BMS-741672.

ACS medicinal chemistry letters

Yang MG, Xiao Z, Cherney RJ, Tebben AJ, Batt DG, Brown GD, Chen J, Cvijic ME, Dabros M, Duncia JV, Galella M, Gardner DS, Khandelwal P, Ko SS, Malley MF, Mo R, Pang J, Rose AV, Santella JB, Shi H, Srivastava A, Traeger SC, Wang B, Xu S, Zhao R, Barrish JC, Mandlekar S, Zhao Q, Carter PH.
PMID: 30891130
ACS Med Chem Lett. 2019 Jan 16;10(3):300-305. doi: 10.1021/acsmedchemlett.8b00439. eCollection 2019 Mar 14.

We encountered a dilemma in the course of studying a series of antagonists of the G-protein coupled receptor CC chemokine receptor-2 (CCR2): compounds with polar C3 side chains exhibited good ion channel selectivity but poor oral bioavailability, whereas compounds...

Radiotherapy for extensive stage small-cell lung cancer.

Lancet (London, England)

Mansfield A, Mandrekar S.
PMID: 25890909
Lancet. 2015 Apr 04;385(9975):1291. doi: 10.1016/S0140-6736(15)60676-6.

No abstract available.

Introducing the Journal of Thoracic Oncology Statistical Series.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Mandrekar SJ, Le-Rademacher J, Adjei AA.
PMID: 32718530
J Thorac Oncol. 2020 Aug;15(8):1257. doi: 10.1016/j.jtho.2020.05.017.

No abstract available.

Effects of carrying school bags on cervical and shoulder posture in static and dynamic conditions in adolescent students.

International journal of adolescent medicine and health

Mandrekar S, Chavhan D, Shyam AK, Sancheti PK.
PMID: 31665119
Int J Adolesc Med Health. 2019 Oct 30; doi: 10.1515/ijamh-2019-0073. Epub 2019 Oct 30.

Background Neck and Back Pain in Students is closely related to the school bags that they carry. There is a dearth of literature in terms of postural changes due to school bags in adolescents, especially those discussing postural changes...

Showing 1 to 12 of 127 entries