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Showing 1 to 12 of 168 entries
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The structure of Toho1 β-lactamase in complex with penicillin reveals the role of Tyr105 in substrate recognition.

FEBS open bio

Langan PS, Vandavasi VG, Weiss KL, Cooper JB, Ginell SL, Coates L.
PMID: 28255534
FEBS Open Bio. 2016 Nov 07;6(12):1170-1177. doi: 10.1002/2211-5463.12132. eCollection 2016 Dec.

The role of the conserved residue Tyr105 in class A β-lactamases has been the subject of investigation using both structural studies and saturation mutagenesis. Both have shown that while it does not need to be strictly conserved for activity,...

National standards for diabetes self-management education.

Diabetes care

Mensing C, Boucher J, Cypress M, Weinger K, Mulcahy K, Barta P, Hosey G, Kopher W, Lasichak A, Lamb B, Mangan M, Norman J, Tanja J, Yauk L, Wisdom K, Adams C.
PMID: 12502650
Diabetes Care. 2003 Jan;26:S149-56. doi: 10.2337/diacare.26.2007.s149.

No abstract available.

Update on the activities of the European Dermato-Epidemiology Network (EDEN).

Dermatology (Basel, Switzerland)

Langan SM, Bouwes Bavinck JN, Coenraads PJ, Diepgen T, Elsner P, Grob JJ, Linder D, Naldi L, Svensson A, Williams HC.
PMID: 16778417
Dermatology. 2006;213(1):1-2. doi: 10.1159/000092828.

No abstract available.

The heat shock response of Mycobacterium tuberculosis: linking gene expression, immunology and pathogenesis.

Comparative and functional genomics

Stewart GR, Wernisch L, Stabler R, Mangan JA, Hinds J, Laing KG, Butcher PD, Young DB.
PMID: 18629273
Comp Funct Genomics. 2002;3(4):348-51. doi: 10.1002/cfg.183.

The regulation of heat shock protein (HSP) expression is critically important to pathogens such as Mycobacterium tuberculosis and dysregulation of the heat shock response results in increased immune recognition of the bacterium and reduced survival during chronic infection. In...

Fundamental-mode cutoff in a photonic crystal fiber with a depressed-index core.

Optics letters

Mangan BJ, Arriaga J, Birks TA, Knight JC, Russell PS.
PMID: 18049637
Opt Lett. 2001 Oct 01;26(19):1469-71. doi: 10.1364/ol.26.001469.

We report a photonic crystal fiber with a depressed-index core doped with fluorine. The effective index of the cladding matches that of the core at an antiguiding wavelength, below which the fiber does not guide light at all.

Acne, isotretinoin and suicide attempts: a critical appraisal.

The British journal of dermatology

Langan SM, Batchelor JM.
PMID: 21615370
Br J Dermatol. 2011 Jun;164(6):1183-5; discussion 1185-6. doi: 10.1111/j.1365-2133.2011.10369.x.

AIM: Sundström et al. (BMJ 2010; 341: c5812) aimed to assess suicide risk before, during and after isotretinoin treatment.HYPOTHESIS: People with severe acne may be at higher risk of attempted suicide regardless of exposure to isotretinoin.SETTING AND DESIGN: This...

Altered CD38/Cyclic ADP-Ribose Signaling Contributes to the Asthmatic Phenotype.

Journal of allergy

Jude JA, Dileepan M, Panettieri RA, Walseth TF, Kannan MS.
PMID: 23213344
J Allergy (Cairo). 2012;2012:289468. doi: 10.1155/2012/289468. Epub 2012 Nov 20.

CD38 is a transmembrane glycoprotein expressed in airway smooth muscle cells. The enzymatic activity of CD38 generates cyclic ADP-ribose from β-NAD. Cyclic ADP-ribose mobilizes intracellular calcium during activation of airway smooth muscle cells by G-protein-coupled receptors through activation of...

Protocol for the development of a CONSORT extension for RCTs using cohorts and routinely collected health data.

Research integrity and peer review

Kwakkenbos L, Juszczak E, Hemkens LG, Sampson M, Fröbert O, Relton C, Gale C, Zwarenstein M, Langan SM, Moher D, Boutron I, Ravaud P, Campbell MK, Mc Cord KA, van Staa TP, Thabane L, Uher R, Verkooijen HM, Benchimol EI, Erlinge D, Sauvé M, Torgerson D, Thombs BD.
PMID: 30397513
Res Integr Peer Rev. 2018 Oct 29;3:9. doi: 10.1186/s41073-018-0053-3. eCollection 2018.

BACKGROUND: Randomized controlled trials (RCTs) are often complex and expensive to perform. Less than one third achieve planned recruitment targets, follow-up can be labor-intensive, and many have limited real-world generalizability. Designs for RCTs conducted using cohorts and routinely collected...

Threshold effect of growth rate on population variability of .

Royal Society open science

Gangan MS, Athale CA.
PMID: 28386413
R Soc Open Sci. 2017 Feb 22;4(2):160417. doi: 10.1098/rsos.160417. eCollection 2017 Feb.

A long-standing question in biology is the effect of growth on cell size. Here, we estimate the effect of

Bilateral Serous Macular Detachment After Attempted Suicide with Pregabalin.

Turkish journal of ophthalmology

Tanyıldız B, Kandemir B, Mangan MS, Tangılntız A, Göktaş E, Şimşek Ş.
PMID: 30405948
Turk J Ophthalmol. 2018 Oct;48(5):254-257. doi: 10.4274/tjo.70923. Epub 2018 Oct 31.

A 24-year-old female presented with bilateral vision loss following attempted suicide with pregabalin. Her best-corrected visual acuity (BCVA) was 20/40 in the right eye and 20/50 in the left eye. The bilateral visual disturbance was associated with serous macular...

BraggNet: integrating Bragg peaks using neural networks.

Journal of applied crystallography

Sullivan B, Archibald R, Azadmanesh J, Vandavasi VG, Langan PS, Coates L, Lynch V, Langan P.
PMID: 31396028
J Appl Crystallogr. 2019 Jul 26;52:854-863. doi: 10.1107/S1600576719008665. eCollection 2019 Aug 01.

Neutron crystallography offers enormous potential to complement structures from X-ray crystallography by clarifying the positions of low-

Room-temperature photo-induced martensitic transformation in a protein crystal. Corrigendum.

IUCrJ

Dajnowicz S, Langan PS, Weiss KL, Ivanov IN, Kovalevsky A.
PMID: 31318360
IUCrJ. 2019 Jun 06;6:781. doi: 10.1107/S2052252519007851. eCollection 2019 Jul 01.

[This retracts the article DOI: 10.1107/S2052252519005761.].

Showing 1 to 12 of 168 entries