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Showing 1 to 12 of 63 entries
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Cow's milk allergy in Dutch children: an epigenetic pilot survey.

Clinical and translational allergy

Petrus NCM, Henneman P, Venema A, Mul A, van Sinderen F, Haagmans M, Mook O, Hennekam RC, Sprikkelman AB, Mannens M.
PMID: 27148440
Clin Transl Allergy. 2016 May 04;6:16. doi: 10.1186/s13601-016-0105-z. eCollection 2016.

BACKGROUND: Cow's milk allergy (CMA) is a common disease in infancy. Early environmental factors are likely to contribute to CMA. It is known that epigenetic gene regulation can be altered by environmental factors. We have set up a proof...

MicroRNAs downregulated in neuropathic pain regulate MeCP2 and BDNF related to pain sensitivity.

FEBS open bio

Manners MT, Tian Y, Zhou Z, Ajit SK.
PMID: 26448907
FEBS Open Bio. 2015 Aug 31;5:733-40. doi: 10.1016/j.fob.2015.08.010. eCollection 2015.

Nerve injury induces chronic pain and dysregulation of microRNAs in dorsal root ganglia (DRG). Several downregulated microRNAs are predicted to target Mecp2. MECP2 mutations cause Rett syndrome and these patients report decreased pain perception. We confirmed MeCP2 upregulation in...

Next-generation sequencing-based genome diagnostics across clinical genetics centers: implementation choices and their effects.

European journal of human genetics : EJHG

Vrijenhoek T, Kraaijeveld K, Elferink M, de Ligt J, Kranendonk E, Santen G, Nijman IJ, Butler D, Claes G, Costessi A, Dorlijn W, van Eyndhoven W, Halley DJ, van den Hout MC, van Hove S, Johansson LF, Jongbloed JD, Kamps R, Kockx CE, de Koning B, Kriek M, Deprez RL, Lunstroo H, Mannens M, Mook OR, Nelen M, Ploem C, Rijnen M, Saris JJ, Sinke R, Sistermans E, van Slegtenhorst M, Sleutels F, van der Stoep N, van Tienhoven M, Vermaat M, Vogel M, Waisfisz Q, Weiss JM, van den Wijngaard A, van Workum W, Ijntema H, van der Zwaag B, van IJcken WF, den Dunnen JT, Veltman JA, Hennekam R, Cuppen E.
PMID: 26269248
Eur J Hum Genet. 2015 Sep;23(9):1270. doi: 10.1038/ejhg.2015.44.

No abstract available.

Founder mutations in hypertrophic cardiomyopathy patients in the Netherlands.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Christiaans I, Nannenberg EA, Dooijes D, Jongbloed RJ, Michels M, Postema PG, Majoor-Krakauer D, van den Wijngaard A, Mannens MM, van Tintelen JP, van Langen IM, Wilde AA.
PMID: 20505798
Neth Heart J. 2010 May;18(5):248-54. doi: 10.1007/BF03091771.

In this part of a series on cardiogenetic founder mutations in the Netherlands, we review the Dutch founder mutations in hypertrophic cardiomyopathy (HCM) patients. HCM is a common autosomal dominant genetic disease affecting at least one in 500 persons...

Acidimetric titration of heavy metal acetates.

Analytical chemistry

Mannens MG.
PMID: 22324610
Anal Chem. 1972 Sep 01;44(11):1876-7. doi: 10.1021/ac60319a038.

No abstract available.

Genome Sequences of Pseudomonas spp. Isolated from Cereal Crops.

Genome announcements

Gardiner DM, Stiller J, Covarelli L, Lindeberg M, Shivas RG, Manners JM.
PMID: 23661484
Genome Announc. 2013 May 09;1(3). doi: 10.1128/genomeA.00209-13.

Compared to those of dicot-infecting bacteria, the available genome sequences of bacteria that infect wheat and barley are limited. Herein, we report the draft genome sequences of four pseudomonads originally isolated from these cereals. These genome sequences provide a...

Three-dimensional kinematics in healthy older adult males during golf swings.

Sports biomechanics

Severin AC, Tackett SA, Barnes CL, Mannen EM.
PMID: 31453740
Sports Biomech. 2019 Aug 27;1-14. doi: 10.1080/14763141.2019.1649452. Epub 2019 Aug 27.

The biomechanics of the golf swing have received considerable attention in previous research. However, existing studies have focused on young athletes, while the kinematics of older golfers remain poorly documented. This study presents kinematic data for healthy senior golfers...

Loss of RANKL in osteocytes dramatically increases cancellous bone mass in the osteogenesis imperfecta mouse (oim).

Bone reports

Zimmerman SM, Heard-Lipsmeyer ME, Dimori M, Thostenson JD, Mannen EM, O'Brien CA, Morello R.
PMID: 30105276
Bone Rep. 2018 Jul 02;9:61-73. doi: 10.1016/j.bonr.2018.06.008. eCollection 2018 Dec.

Osteogenesis imperfecta (OI) is characterized by osteopenia and bone fragility, and OI patients during growth often exhibit high bone turnover with the net result of low bone mass. Recent evidence shows that osteocytes significantly affect bone remodeling under physiological...

Rare, Unusual Causality of Acute Appendicitis.

Journal of gastrointestinal cancer

Janssens KK, Mannens D, Declercq S, Maes M, Van Outryve SM.
PMID: 32860203
J Gastrointest Cancer. 2021 Jun;52(2):759-765. doi: 10.1007/s12029-020-00503-y.

No abstract available.

Radiographic Findings in Flexion Instability after Total Knee Arthroplasty.

The journal of knee surgery

Howie CM, Mears SC, Barnes CL, Mannen EM, Stambough JB.
PMID: 34507362
J Knee Surg. 2021 Sep 10; doi: 10.1055/s-0041-1735279. Epub 2021 Sep 10.

Flexion instability (FI) is one of the leading causes of knee pain and revision surgery. Generally, the biomechanical etiology is considered to be a larger flexion than extension gap. This may be due to mismatch of components sizes to...

Exploring infant hip position and muscle activity in common baby gear and orthopedic devices.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Siddicky SF, Wang J, Rabenhorst B, Buchele L, Mannen EM.
PMID: 34566253
J Orthop Res. 2021 May;39(5):941-949. doi: 10.1002/jor.24818. Epub 2020 Jul 31.

Infant positioning in daily life may affect hip development. While neonatal animal studies indicate detrimental relationships between inactive lower extremities and hip development and dysplasia, no research has explored infant hip biomechanics experimentally. This study evaluated hip joint position...

Management of Periprosthetic Joint Infection and Extensor Mechanism Disruption With Modular Knee Fusion: Clinical and Biomechanical Outcomes.

Arthroplasty today

Mayes WH, Severin AC, Mannen EM, Edwards PK, Barnes CL, Stambough JB, Mears SC.
PMID: 33718555
Arthroplast Today. 2021 Feb 26;8:46-52. doi: 10.1016/j.artd.2020.12.008. eCollection 2021 Apr.

BACKGROUND: Extensor mechanism disruption (EMD) combined with periprosthetic joint infection (PJI) after total knee arthroplasty are life-changing complications. The literature suggests many eventually receive above-knee amputation and lose ambulatory function. An alternative is modular knee fusion (KF), but little...

Showing 1 to 12 of 63 entries