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Showing 1 to 12 of 15 entries
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Trends in pharmacological sciences

Mantyh P.
PMID: 10918628
Trends Pharmacol Sci. 2000 Aug;21(8):286-7. doi: 10.1016/s0165-6147(00)01495-4.

No abstract available.

Response to Letter to the Editor.

Diseases of the colon and rectum

Sun Z, Turner MC, Migaly J, Mantyh CR.
PMID: 29624554
Dis Colon Rectum. 2018 May;61(5):e36-e37. doi: 10.1097/DCR.0000000000001092.

No abstract available.

Treating osteoarthritis pain: mechanisms of action of acetaminophen, nonsteroidal anti-inflammatory drugs, opioids, and nerve growth factor antibodies.

Postgraduate medicine

D'Arcy Y, Mantyh P, Yaksh T, Donevan S, Hall J, Sadrarhami M, Viktrup L.
PMID: 34252357
Postgrad Med. 2021 Nov;133(8):879-894. doi: 10.1080/00325481.2021.1949199. Epub 2021 Jul 12.

Osteoarthritis (OA) is a common difficult-to-treat condition where the goal, in the absence of disease-modifying treatments, is to alleviate symptoms such as pain and loss of function. Acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs), and opioids are common pharmacologic treatments for...

Epidermal Nerve Fiber Quantification in Patients With Erythromelalgia.

JAMA dermatology

Mantyh WG, Dyck PJB, Dyck PJ, Engelstad JK, Litchy WJ, Sandroni P, Davis MDP.
PMID: 27926760
JAMA Dermatol. 2017 Feb 01;153(2):162-167. doi: 10.1001/jamadermatol.2016.4404.

IMPORTANCE: Erythromelalgia is a clinical diagnosis based on intermittent warmth, erythema, and pain in the distal extremities. One problem facing physicians is how to objectively test for this disease. Given that other painful conditions of the distal extremities (ie,...

The involvement of prostaglandins in tumorigenesis, tumor-induced osteolysis and bone cancer pain.

Journal of musculoskeletal & neuronal interactions

Sabino MC, Ghilardi JR, Feia KJ, Jongen JL, Keyser CP, Luger NM, Mach DB, Peters CM, Rogers SD, Schwei MJ, De Filipe C, Mantyh PW.
PMID: 15758394
J Musculoskelet Neuronal Interact. 2002 Dec;2(6):561-2.

No abstract available.

Bone cancer pain: from mechanism to model to therapy.

Pain medicine (Malden, Mass.)

Honore P, Mantyh PW.
PMID: 15101876
Pain Med. 2000 Dec;1(4):303-9. doi: 10.1046/j.1526-4637.2000.00047.x.

Although bone cancer pain can be severe and is relatively common, very little is known about the basic mechanisms that generate and maintain this debilitating pain. To begin to define the mechanisms that give rise to bone cancer pain,...

Combined Primary Resection with Hepatic Artery Infusion Pump Implantation Is Safe for Unresectable Colorectal Liver Metastases.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

Turley MC, Moore C, Creasy JM, Sharib J, Lan B, Thacker JKM, Migaly J, Zani S, Allen PJ, Mantyh CR, Lidsky ME.
PMID: 34820727
J Gastrointest Surg. 2021 Nov 24; doi: 10.1007/s11605-021-05195-8. Epub 2021 Nov 24.

BACKGROUND: Colorectal liver metastases (CRLM) are the most common cause of disease-specific mortality in patients with colorectal cancer. Hepatic artery infusion (HAI) combined with systemic chemotherapy improves survival for these patients. The safety of colorectal resection at the time...

Activation of lamina I spinal cord neurons that express the substance P receptor in visceral nociception and hyperalgesia.

The journal of pain

Honoré P, Kamp EH, Rogers SD, Gebhart GF, Mantyh PW.
PMID: 14622848
J Pain. 2002 Feb;3(1):3-11. doi: 10.1054/jpai.2002.27001.

Spinal lamina I neurons expressing the substance P receptor (SPR) have been shown to play a role in the transmission of somatic inflammatory and neuropathic pain. To evaluate their involvement in visceral nociception in both the noninflamed and inflamed...

Heterogeneous distribution of tau pathology in the behavioural variant of Alzheimer's disease.

Journal of neurology, neurosurgery, and psychiatry

Singleton E, Hansson O, Pijnenburg YAL, La Joie R, Mantyh WG, Tideman P, Stomrud E, Leuzy A, Johansson M, Strandberg O, Smith R, Berendrecht E, Miller BL, Iaccarino L, Edwards L, Strom A, Wolters EE, Coomans E, Visser D, Golla SSV, Tuncel H, Bouwman F, Van Swieten JC, Papma JM, van Berckel B, Scheltens P, Dijkstra AA, Rabinovici GD, Ossenkoppele R.
PMID: 33850001
J Neurol Neurosurg Psychiatry. 2021 Apr 13; doi: 10.1136/jnnp-2020-325497. Epub 2021 Apr 13.

OBJECTIVE: The clinical phenotype of the rare behavioural variant of Alzheimer's disease (bvAD) is insufficiently understood. Given the strong clinico-anatomical correlations of tau pathology in AD, we investigated the distribution of tau deposits in bvAD, in-vivo and ex-vivo, using...

Reconstruction techniques after proctectomy: what's the best?.

Clinics in colon and rectal surgery

de la Fuente SG, Mantyh CR.
PMID: 20011203
Clin Colon Rectal Surg. 2007 Aug;20(3):221-30. doi: 10.1055/s-2007-984866.

There are approximately 40,000 new rectal cancer cases diagnosed each year in the United States, representing the second most common gastrointestinal malignancy (behind colon cancer). With the advent of sphincter preserving techniques, patients with mid and low colorectal cancers...

Mice with cancer-induced bone pain show a marked decline in day/night activity.

Pain reports

Majuta LA, Guedon JG, Mitchell SAT, Kuskowski MA, Mantyh PW.
PMID: 29392229
Pain Rep. 2017 Aug 11;2(5):e614. doi: 10.1097/PR9.0000000000000614. eCollection 2017 Sep.

INTRODUCTION: Cancer-induced bone pain (CIBP) is the most common type of pain with cancer. In humans, this pain can be difficult to control and highly disabling. A major problem with CIBP in humans is that it increases on weight-bearing...

Progressive dysexecutive syndrome due to Alzheimer's disease: a description of 55 cases and comparison to other phenotypes.

Brain communications

Townley RA, Graff-Radford J, Mantyh WG, Botha H, Polsinelli AJ, Przybelski SA, Machulda MM, Makhlouf AT, Senjem ML, Murray ME, Reichard RR, Savica R, Boeve BF, Drubach DA, Josephs KA, Knopman DS, Lowe VJ, Jack CR, Petersen RC, Jones DT.
PMID: 32671341
Brain Commun. 2020;2(1):fcaa068. doi: 10.1093/braincomms/fcaa068. Epub 2020 May 27.

We report a group of patients presenting with a progressive dementia syndrome characterized by predominant dysfunction in core executive functions, relatively young age of onset and positive biomarkers for Alzheimer's pathophysiology. Atypical frontal, dysexecutive/behavioural variants and early-onset variants of...

Showing 1 to 12 of 15 entries