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Showing 1 to 12 of 32 entries
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MAP1B Interaction with the FW Domain of the Autophagic Receptor Nbr1 Facilitates Its Association to the Microtubule Network.

International journal of cell biology

Marchbank K, Waters S, Roberts RG, Solomon E, Whitehouse CA.
PMID: 22654911
Int J Cell Biol. 2012;2012:208014. doi: 10.1155/2012/208014. Epub 2012 May 10.

Selective autophagy is a process whereby specific targeted cargo proteins, aggregates, or organelles are sequestered into double-membrane-bound phagophores before fusion with the lysosome for protein degradation. It has been demonstrated that the microtubule network is important for the formation...

Discovery of a New Natural Product and a Deactivation of a Quorum Sensing System by Culturing a "Producer" Bacterium With a Heat-Killed "Inducer" Culture.

Frontiers in microbiology

Liang L, Sproule A, Haltli B, Marchbank DH, Berrué F, Overy DP, McQuillan K, Lanteigne M, Duncan N, Correa H, Kerr RG.
PMID: 30705672
Front Microbiol. 2019 Jan 17;9:3351. doi: 10.3389/fmicb.2018.03351. eCollection 2018.

Herein we describe a modified bacterial culture methodology as a tool to discover new natural products via supplementing actinomycete fermentation media with autoclaved cultures of "inducer" microbes. Using seven actinomycetes and four inducer microbes, we detected 28 metabolites that...

Homodimeric Minimal Factor H: .

Frontiers in immunology

Kamala O, Malik TH, Hallam TM, Cox TE, Yang Y, Vyas F, Luli S, Connelly C, Gibson B, Smith-Jackson K, Denton H, Pappworth IY, Huang L, Kavanagh D, Pickering MC, Marchbank KJ.
PMID: 34956184
Front Immunol. 2021 Dec 09;12:752916. doi: 10.3389/fimmu.2021.752916. eCollection 2021.

C3 glomerulopathy (C3G) is associated with dysregulation of the alternative pathway (AP) of complement and treatment options remain inadequate. Factor H (FH) is a potent regulator of the AP. An in-depth analysis of FH-related protein dimerised minimal (mini)-FH constructs...

Correction: Marked variability in bioactivity between commercially available bovine colostrum for human use; implications for clinical trials.

PloS one

Playford RJ, Cattell M, Marchbank T.
PMID: 33022011
PLoS One. 2020 Oct 06;15(10):e0240392. doi: 10.1371/journal.pone.0240392. eCollection 2020.

[This corrects the article DOI: 10.1371/journal.pone.0234719.].

C3 Glomerulopathy and Related Disorders in Children: Etiology-Phenotype Correlation and Outcomes.

Clinical journal of the American Society of Nephrology : CJASN

Wong EKS, Marchbank KJ, Lomax-Browne H, Pappworth IY, Denton H, Cooke K, Ward S, McLoughlin AC, Richardson G, Wilson V, Harris CL, Morgan BP, Hakobyan S, McAlinden P, Gale DP, Maxwell H, Christian M, Malcomson R, Goodship THJ, Marks SD, Pickering MC, Kavanagh D, Cook HT, Johnson SA.
PMID: 34551983
Clin J Am Soc Nephrol. 2021 Nov;16(11):1639-1651. doi: 10.2215/CJN.00320121. Epub 2021 Sep 22.

BACKGROUND AND OBJECTIVES: Membranoproliferative GN and C3 glomerulopathy are rare and overlapping disorders associated with dysregulation of the alternative complement pathway. Specific etiologic data for pediatric membranoproliferative GN/C3 glomerulopathy are lacking, and outcome data are based on retrospective studies...

C3 Glomerulopathy and Related Disorders in Children: Etiology-Phenotype Correlation and Outcomes.

Clinical journal of the American Society of Nephrology : CJASN

Wong EKS, Marchbank KJ, Lomax-Browne H, Pappworth IY, Denton H, Cooke K, Ward S, McLoughlin AC, Richardson G, Wilson V, Harris CL, Morgan BP, Hakobyan S, McAlinden P, Gale DP, Maxwell H, Christian M, Malcomson R, Goodship THJ, Marks SD, Pickering MC, Kavanagh D, Cook HT, Johnson SA.
PMID: 34551983
Clin J Am Soc Nephrol. 2021 Nov;16(11):1639-1651. doi: 10.2215/CJN.00320121. Epub 2021 Sep 22.

BACKGROUND AND OBJECTIVES: Membranoproliferative GN and C3 glomerulopathy are rare and overlapping disorders associated with dysregulation of the alternative complement pathway. Specific etiologic data for pediatric membranoproliferative GN/C3 glomerulopathy are lacking, and outcome data are based on retrospective studies...

Video-assisted cardioscopy in a patient with left ventricular tumor of unknown etiology.

Interactive cardiovascular and thoracic surgery

Junemann-Ramirez M, Conn G, Marshall A, Marchbank A.
PMID: 17670371
Interact Cardiovasc Thorac Surg. 2005 Apr;4(2):123-5. doi: 10.1510/icvts.2004.093229. Epub 2005 Feb 07.

Ventricular tumors are a rare clinical entity with limited possibilities for excision diagnosis. For benign conditions surgical excision is the treatment of choice. A case presenting as a clinical conundrum with left ventricular tumor and complex past medical history...

Identification of specific SUVmax ratios enhances diagnostic accuracy for staging of intrathoracic nodes in lung cancer.

Nuclear medicine communications

Pencharz D, Matei N, Jeon J, Myerson J, Marchbank ND.
PMID: 34528931
Nucl Med Commun. 2021 Oct 01;42(10):1130-1134. doi: 10.1097/MNM.0000000000001441.

INTRODUCTION: Studies demonstrating limited accuracy of 'positive' and 'negative' lymph nodes on fluorodeoxyglucose (FDG) PET-CT in staging for lung cancer have led to guidelines stating mediastinal nodes enlarged on computed tomography, irrespective of FDG uptake, require endobronchial ultrasound (EBUS)-transbronchial...

Surgical factors associated with new-onset postoperative atrial fibrillation after lung resection: the EPAFT multicentre study.

Postgraduate medical journal

Crispi V, Isaac E, Abah U, Shackcloth M, Lopez E, Eadington T, Taylor M, Kandadai R, Marshall NR, Gurung A, Rogers LJ, Marchbank A, Qadri S, Loubani M.
PMID: 33310899
Postgrad Med J. 2020 Dec 11; doi: 10.1136/postgradmedj-2020-138904. Epub 2020 Dec 11.

PURPOSE OF THE STUDY: Postoperative atrial fibrillation (POAF) is a recognised complication in approximately 10% of major lung resections. In order to best target preoperative treatment, this study aimed at determining the association of incidence of POAF in patients...

Homodimeric Minimal Factor H: .

Frontiers in immunology

Kamala O, Malik TH, Hallam TM, Cox TE, Yang Y, Vyas F, Luli S, Connelly C, Gibson B, Smith-Jackson K, Denton H, Pappworth IY, Huang L, Kavanagh D, Pickering MC, Marchbank KJ.
PMID: 34956184
Front Immunol. 2021 Dec 09;12:752916. doi: 10.3389/fimmu.2021.752916. eCollection 2021.

C3 glomerulopathy (C3G) is associated with dysregulation of the alternative pathway (AP) of complement and treatment options remain inadequate. Factor H (FH) is a potent regulator of the AP. An in-depth analysis of FH-related protein dimerised minimal (mini)-FH constructs...

Absence of clinical benefit of FDG PET-CT in staging T1 part-solid lung adenocarcinoma.

Clinical radiology

Pencharz D, Modi S, Bandyopadhyay S, Alhun U, Marchbank N, Patel A, Wagner T.
PMID: 34953570
Clin Radiol. 2021 Dec 22; doi: 10.1016/j.crad.2021.11.013. Epub 2021 Dec 22.

AIM: To assess the rates of nodal and metastatic disease and change in management when staging part-solid T1 lung adenocarcinomas using integrated 2-[MATERIALS AND METHODS: This was a retrospective review of PET-CT examinations performed to stage radiologically suspected T1...

Diastereoselective cascade synthesis of azabicyclo[3.1.0]hexanes from acyclic precursors.

Chemical communications (Cambridge, England)

Böhmer J, Grigg R, Marchbank JD.
PMID: 12119714
Chem Commun (Camb). 2002 Apr 07;(7):768-9. doi: 10.1039/b110890e.

The diastereoselective synthesis of azabicyclo[3.1.0]hexanes bearing different substituents on all positions of the cyclopropane ring has been achieved in moderate to good yields.

Showing 1 to 12 of 32 entries