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Showing 1 to 12 of 40 entries
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Benzylamine and Thenylamine Derived Drugs Induce Apoptosis and Reduce Proliferation, Migration and Metastasis Formation in Melanoma Cells.

Frontiers in oncology

Mojena M, Povo-Retana A, González-Ramos S, Fernández-García V, Regadera J, Zazpe A, Artaiz I, Martín-Sanz P, Ledo F, Boscá L.
PMID: 30191142
Front Oncol. 2018 Aug 23;8:328. doi: 10.3389/fonc.2018.00328. eCollection 2018.

Melanomas are heterogeneous and aggressive tumors, and one of the worse in prognosis. Melanoma subtypes follow distinct pathways until terminal oncogenic transformation. Here, we have evaluated a series of molecules that exhibit potent cytotoxic effects over the murine and...

Clinical Features of Headache in Patients With Diagnosis of Definite Vestibular Migraine: The VM-Phenotypes Projects.

Frontiers in neurology

Teggi R, Colombo B, Albera R, Asprella Libonati G, Balzanelli C, Batuecas Caletrio A, Casani AP, Espinosa-Sanchez JM, Gamba P, Lopez-Escamez JA, Lucisano S, Mandalà M, Neri G, Nuti D, Pecci R, Russo A, Martin-Sanz E, Sanz R, Tedeschi G, Torelli P, Vannucchi P, Comi G, Bussi M.
PMID: 29922214
Front Neurol. 2018 Jun 05;9:395. doi: 10.3389/fneur.2018.00395. eCollection 2018.

Migraine is a common neurological disorder characterized by episodic headaches with specific features, presenting familial aggregation. Migraine is associated with episodic vertigo, named Vestibular Migraine (VM) whose diagnosis mainly rely on clinical history showing a temporary association of symptoms....

Oral Consumption of Bread from an RNAi Wheat Line with Strongly Silenced Gliadins Elicits No Immunogenic Response in a Pilot Study with Celiac Disease Patients.

Nutrients

Guzmán-López MH, Sánchez-León S, Marín-Sanz M, Comino I, Segura V, Vaquero L, Rivero-Lezcano OM, Pastor J, Sousa C, Vivas S, Barro F.
PMID: 34960101
Nutrients. 2021 Dec 18;13(12). doi: 10.3390/nu13124548.

Celiac disease (CD) is a genetically predisposed, T cell-mediated and autoimmune-like disorder caused by dietary exposure to the storage proteins of wheat and related cereals. A gluten-free diet (GFD) is the only treatment available for CD. The celiac immune...

A Bioinformatic Workflow for InDel Analysis in the Wheat Multi-Copy α-Gliadin Gene Family Engineered with CRISPR/Cas9.

International journal of molecular sciences

Guzmán-López MH, Marín-Sanz M, Sánchez-León S, Barro F.
PMID: 34884880
Int J Mol Sci. 2021 Dec 03;22(23). doi: 10.3390/ijms222313076.

The α-gliadins of wheat, along with other gluten components, are responsible for bread viscoelastic properties. However, they are also related to human pathologies as celiac disease or non-celiac wheat sensitivity. CRISPR/Cas was successfully used to knockout α-gliadin genes in...

How Does Water Availability Affect the Allocation to Bark in a Mediterranean Conifer?.

Frontiers in plant science

Martín-Sanz RC, San-Martín R, Poorter H, Vázquez A, Climent J.
PMID: 31164894
Front Plant Sci. 2019 May 21;10:607. doi: 10.3389/fpls.2019.00607. eCollection 2019.

Bark thickness is a key structural feature in woody plants in the protection against fire. We used 19 provenances of

A Bioinformatic Workflow for InDel Analysis in the Wheat Multi-Copy α-Gliadin Gene Family Engineered with CRISPR/Cas9.

International journal of molecular sciences

Guzmán-López MH, Marín-Sanz M, Sánchez-León S, Barro F.
PMID: 34884880
Int J Mol Sci. 2021 Dec 03;22(23). doi: 10.3390/ijms222313076.

The α-gliadins of wheat, along with other gluten components, are responsible for bread viscoelastic properties. However, they are also related to human pathologies as celiac disease or non-celiac wheat sensitivity. CRISPR/Cas was successfully used to knockout α-gliadin genes in...

Improving spatial resolution of a LTQ Orbitrap MALDI source.

Journal of the American Society for Mass Spectrometry

Montero R, Abad-García B, Garate J, Martín-Saiz L, Barceló-Coblijn G, Fernandez JA.
PMID: 32662650
J Am Soc Mass Spectrom. 2020 Jul 14; doi: 10.1021/jasms.0c00133. Epub 2020 Jul 14.

Here we present a simple and cost effective procedure to improve the spatial resolution of the commercial MALDI source of a LTQ Orbitrap. Based in spatial filtering techniques, we demonstrate that, with minimal modifications of the original set up,...

Fungal Planet description sheets: 868-950.

Persoonia

Crous PW, Carnegie AJ, Wingfield MJ, Sharma R, Mughini G, Noordeloos ME, Santini A, Shouche YS, Bezerra JDP, Dima B, Guarnaccia V, Imrefi I, Jurjević Ž, Knapp DG, Kovács GM, Magistà D, Perrone G, Rämä T, Rebriev YA, Shivas RG, Singh SM, Souza-Motta CM, Thangavel R, Adhapure NN, Alexandrova AV, Alfenas AC, Alfenas RF, Alvarado P, Alves AL, Andrade DA, Andrade JP, Barbosa RN, Barili A, Barnes CW, Baseia IG, Bellanger JM, Berlanas C, Bessette AE, Bessette AR, Biketova AY, Bomfim FS, Brandrud TE, Bransgrove K, Brito ACQ, Cano-Lira JF, Cantillo T, Cavalcanti AD, Cheewangkoon R, Chikowski RS, Conforto C, Cordeiro TRL, Craine JD, Cruz R, Damm U, de Oliveira RJV, de Souza JT, de Souza HG, Dearnaley JDW, Dimitrov RA, Dovana F, Erhard A, Esteve-Raventós F, Félix CR, Ferisin G, Fernandes RA, Ferreira RJ, Ferro LO, Figueiredo CN, Frank JL, Freire KTLS, García D, Gené J, Gêsiorska A, Gibertoni TB, Gondra RAG, Gouliamova DE, Gramaje D, Guard F, Gusmão LFP, Haitook S, Hirooka Y, Houbraken J, Hubka V, Inamdar A, Iturriaga T, Iturrieta-González I, Jadan M, Jiang N, Justo A, Kachalkin AV, Kapitonov VI, Karadelev M, Karakehian J, Kasuya T, Kautmanová I, Kruse J, Kušan I, Kuznetsova TA, Landell MF, Larsson KH, Lee HB, Lima DX, Lira CRS, Machado AR, Madrid H, Magalhães OMC, Majerova H, Malysheva EF, Mapperson RR, Marbach PAS, Martín MP, Martín-Sanz A, Matočec N, McTaggart AR, Mello JF, Melo RFR, Mešić A, Michereff SJ, Miller AN, Minoshima A, Molinero-Ruiz L, Morozova OV, Mosoh D, Nabe M, Naik R, Nara K, Nascimento SS, Neves RP, Olariaga I, Oliveira RL, Oliveira TGL, Ono T, Ordoñez ME, Ottoni AM, Paiva LM, Pancorbo F, Pant B, Pawłowska J, Peterson SW, Raudabaugh DB, Rodríguez-Andrade E, Rubio E, Rusevska K, Santiago ALCMA, Santos ACS, Santos C, Sazanova NA, Shah S, Sharma J, Silva BDB, Siquier JL, Sonawane MS, Stchigel AM, Svetasheva T, Tamakeaw N, Telleria MT, Tiago PV, Tian CM, Tkalčec Z, Tomashevskaya MA, Truong HH, Vecherskii MV, Visagie CM, Vizzini A, Yilmaz N, Zmitrovich IV, Zvyagina EA, Boekhout T, Kehlet T, Læssøe T, Groenewald JZ.
PMID: 31551622
Persoonia. 2019 Jun;42:291-473. doi: 10.3767/persoonia.2019.42.11. Epub 2019 Jul 19.

Novel species of fungi described in this study include those from various countries as follows:

Genetics, Host Range, and Molecular and Pathogenic Characterization of .

Frontiers in plant science

Martín-Sanz A, Rueda S, García-Carneros AB, González-Fernández S, Miranda-Fuentes P, Castuera-Santacruz S, Molinero-Ruiz L.
PMID: 29593756
Front Plant Sci. 2018 Mar 09;9:288. doi: 10.3389/fpls.2018.00288. eCollection 2018.

Verticillium wilt and leaf mottle of sunflower, caused by the fungus

Therapeutic illusion: another frontier in Ménière's disease.

Annals of translational medicine

Pérez-Fernández N, Martín-Sanz E.
PMID: 27868031
Ann Transl Med. 2016 Oct;4:S63. doi: 10.21037/atm.2016.10.61.

No abstract available.

Evaluation of epigenetic modulation of cyclooxygenase-2 as a prognostic marker for hepatocellular carcinoma.

Oncogenesis

Fernández-Alvarez A, Llorente-Izquierdo C, Mayoral R, Agra N, Boscá L, Casado M, Martín-Sanz P.
PMID: 23552739
Oncogenesis. 2012 Jul 09;1:e23. doi: 10.1038/oncsis.2012.23.

Cyclooxygenases (COX-1 and 2) catalyze the first step in prostanoid biosynthesis. They are implicated in homeostatic processes with an important role in inflammation and carcinogenesis. In the liver, COX-2 expression is restricted to proliferation or dedifferentiation situations. The COX-2...

Effect of rhodium (III) complex on experimental carcinogenesis in the livers of rats treated with thioacetamide.

Biological trace element research

Cascales C, Craciunescu DG, Martín-Sanz P, Cascales M.
PMID: 24254504
Biol Trace Elem Res. 1986 Dec;11(1):65-73. doi: 10.1007/BF02795525.

Enzyme activities and protein content were determined in the cytosolic and mitochondrial fractions of liver homogenates obtained from Rh(III) complex-, thioacetamide- and thioacetamide + Rh(III) complex-treated rats.The Rh(III) complex administered to nonthioacetamide-treated rats produced no significant changes either in...

Showing 1 to 12 of 40 entries