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Genetic Deletion of Akt3 Induces an Endophenotype Reminiscent of Psychiatric Manifestations in Mice.

Frontiers in molecular neuroscience

Bergeron Y, Bureau G, Laurier-Laurin MÉ, Asselin E, Massicotte G, Cyr M.
PMID: 28442992
Front Mol Neurosci. 2017 Apr 10;10:102. doi: 10.3389/fnmol.2017.00102. eCollection 2017.

The protein kinase B (PKB/Akt), found in three distinctive isoforms (PKBα/Akt1, PKBβ/Akt2, PKBγ/Akt3), is implicated in a variety of cellular processes such as cell development, growth and survival. Although Akt3 is the most expressed isoform in the brain, its...

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Bergeron Y, Bureau G, Laurier-Laurin MÉ, et al. Genetic Deletion of Akt3 Induces an Endophenotype Reminiscent of Psychiatric Manifestations in Mice. Front Mol Neurosci. 2017;10:102doi: 10.3389/fnmol.2017.00102.
Bergeron, Y., Bureau, G., Laurier-Laurin, M. �. �., Asselin, E., Massicotte, G., & Cyr, M. (2017). Genetic Deletion of Akt3 Induces an Endophenotype Reminiscent of Psychiatric Manifestations in Mice. Frontiers in molecular neuroscience, 10102. https://doi.org/10.3389/fnmol.2017.00102
Bergeron, Yan, et al. "Genetic Deletion of Akt3 Induces an Endophenotype Reminiscent of Psychiatric Manifestations in Mice." Frontiers in molecular neuroscience vol. 10 (2017): 102. doi: https://doi.org/10.3389/fnmol.2017.00102
Bergeron Y, Bureau G, Laurier-Laurin MÉ, Asselin E, Massicotte G, Cyr M. Genetic Deletion of Akt3 Induces an Endophenotype Reminiscent of Psychiatric Manifestations in Mice. Front Mol Neurosci. 2017 Apr 10;10:102. doi: 10.3389/fnmol.2017.00102. eCollection 2017. PMID: 28442992; PMCID: PMC5385361.
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Incidence and Outcomes of Acute Implant Extrusion Following Anterior Cervical Spine Surgery.

Global spine journal

Smith GA, Pace J, Corriveau M, Lee S, Mroz TE, Nassr A, Fehlings MG, Hart RA, Hilibrand AS, Arnold PM, Bumpass DB, Gokaslan Z, Bydon M, Fogelson JL, Massicotte EM, Riew KD, Steinmetz MP.
PMID: 28451490
Global Spine J. 2017 Apr;7(1):40S-45S. doi: 10.1177/2192568216686752. Epub 2017 Apr 01.

STUDY DESIGN: Multi-institutional retrospective case series of 8887 patients who underwent anterior cervical spine surgery.OBJECTIVE: Anterior decompression from discectomy or corpectomy is not without risk. Surgical morbidity ranges from 9% to 20% and is likely underreported. Little is known...

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Smith GA, Pace J, Corriveau M, et al. Incidence and Outcomes of Acute Implant Extrusion Following Anterior Cervical Spine Surgery. Global Spine J. 2017;7(1):40S-45Sdoi: 10.1177/2192568216686752.
Smith, G. A., Pace, J., Corriveau, M., Lee, S., Mroz, T. E., Nassr, A., Fehlings, M. G., Hart, R. A., Hilibrand, A. S., Arnold, P. M., Bumpass, D. B., Gokaslan, Z., Bydon, M., Fogelson, J. L., Massicotte, E. M., Riew, K. D., & Steinmetz, M. P. (2017). Incidence and Outcomes of Acute Implant Extrusion Following Anterior Cervical Spine Surgery. Global spine journal, 7(1), 40S-45S. https://doi.org/10.1177/2192568216686752
Smith, Gabriel A, et al. "Incidence and Outcomes of Acute Implant Extrusion Following Anterior Cervical Spine Surgery." Global spine journal vol. 7,1 (2017): 40S-45S. doi: https://doi.org/10.1177/2192568216686752
Smith GA, Pace J, Corriveau M, Lee S, Mroz TE, Nassr A, Fehlings MG, Hart RA, Hilibrand AS, Arnold PM, Bumpass DB, Gokaslan Z, Bydon M, Fogelson JL, Massicotte EM, Riew KD, Steinmetz MP. Incidence and Outcomes of Acute Implant Extrusion Following Anterior Cervical Spine Surgery. Global Spine J. 2017 Apr;7(1):40S-45S. doi: 10.1177/2192568216686752. Epub 2017 Apr 01. PMID: 28451490; PMCID: PMC5400179.
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Misplaced Cervical Screws Requiring Reoperation.

Global spine journal

Peterson JC, Arnold PM, Smith ZA, Hsu WK, Fehlings MG, Hart RA, Hilibrand AS, Nassr A, Rahman RK, Tannoury CA, Tannoury T, Mroz TE, Currier BL, De Giacomo AF, Fogelson JL, Jobse BC, Massicotte EM, Riew KD.
PMID: 28451491
Global Spine J. 2017 Apr;7(1):46S-52S. doi: 10.1177/2192568216687527. Epub 2017 Apr 01.

STUDY DESIGN: A multicenter, retrospective case series.OBJECTIVE: In the past several years, screw fixation of the cervical spine has become commonplace. For the most part, this is a safe, low-risk procedure. While rare, screw backout or misplaced screws can...

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Peterson JC, Arnold PM, Smith ZA, et al. Misplaced Cervical Screws Requiring Reoperation. Global Spine J. 2017;7(1):46S-52Sdoi: 10.1177/2192568216687527.
Peterson, J. C., Arnold, P. M., Smith, Z. A., Hsu, W. K., Fehlings, M. G., Hart, R. A., Hilibrand, A. S., Nassr, A., Rahman, R. K., Tannoury, C. A., Tannoury, T., Mroz, T. E., Currier, B. L., De Giacomo, A. F., Fogelson, J. L., Jobse, B. C., Massicotte, E. M., & Riew, K. D. (2017). Misplaced Cervical Screws Requiring Reoperation. Global spine journal, 7(1), 46S-52S. https://doi.org/10.1177/2192568216687527
Peterson, Jeremy C, et al. "Misplaced Cervical Screws Requiring Reoperation." Global spine journal vol. 7,1 (2017): 46S-52S. doi: https://doi.org/10.1177/2192568216687527
Peterson JC, Arnold PM, Smith ZA, Hsu WK, Fehlings MG, Hart RA, Hilibrand AS, Nassr A, Rahman RK, Tannoury CA, Tannoury T, Mroz TE, Currier BL, De Giacomo AF, Fogelson JL, Jobse BC, Massicotte EM, Riew KD. Misplaced Cervical Screws Requiring Reoperation. Global Spine J. 2017 Apr;7(1):46S-52S. doi: 10.1177/2192568216687527. Epub 2017 Apr 01. PMID: 28451491; PMCID: PMC5400184.
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Cost-utility analysis of posterior minimally invasive fusion compared with conventional open fusion for lumbar spondylolisthesis.

SAS journal

Rampersaud YR, Gray R, Lewis SJ, Massicotte EM, Fehlings MG.
PMID: 25802665
SAS J. 2011 Jun 01;5(2):29-35. doi: 10.1016/j.esas.2011.02.001. eCollection 2011.

BACKGROUND: The utility and cost of minimally invasive surgical (MIS) fusion remain controversial. The primary objective of this study was to compare the direct economic impact of 1- and 2-level fusion for grade I or II degenerative or isthmic...

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Rampersaud YR, Gray R, Lewis SJ, et al. Cost-utility analysis of posterior minimally invasive fusion compared with conventional open fusion for lumbar spondylolisthesis. SAS J. 2011;5(2):29-35doi: 10.1016/j.esas.2011.02.001.
Rampersaud, Y. R., Gray, R., Lewis, S. J., Massicotte, E. M., & Fehlings, M. G. (2011). Cost-utility analysis of posterior minimally invasive fusion compared with conventional open fusion for lumbar spondylolisthesis. SAS journal, 5(2), 29-35. https://doi.org/10.1016/j.esas.2011.02.001
Rampersaud, Y Raja, et al. "Cost-utility analysis of posterior minimally invasive fusion compared with conventional open fusion for lumbar spondylolisthesis." SAS journal vol. 5,2 (2011): 29-35. doi: https://doi.org/10.1016/j.esas.2011.02.001
Rampersaud YR, Gray R, Lewis SJ, Massicotte EM, Fehlings MG. Cost-utility analysis of posterior minimally invasive fusion compared with conventional open fusion for lumbar spondylolisthesis. SAS J. 2011 Jun 01;5(2):29-35. doi: 10.1016/j.esas.2011.02.001. eCollection 2011. PMID: 25802665; PMCID: PMC4365621.
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Correction: Regulation of Tyrosine Phosphatase STEP61 by Protein Kinase A during Motor Skill Learning in Mice.

PloS one

Chagniel L, Bergeron Y, Bureau G, Massicotte G, Cyr M.
PMID: 26960137
PLoS One. 2016 Mar 09;11(3):e0150220. doi: 10.1371/journal.pone.0150220. eCollection 2016.

No abstract available.

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Chagniel L, Bergeron Y, Bureau G, et al. Correction: Regulation of Tyrosine Phosphatase STEP61 by Protein Kinase A during Motor Skill Learning in Mice. PLoS One. 2016;11(3):e0150220doi: 10.1371/journal.pone.0150220.
Chagniel, L., Bergeron, Y., Bureau, G., Massicotte, G., & Cyr, M. (2016). Correction: Regulation of Tyrosine Phosphatase STEP61 by Protein Kinase A during Motor Skill Learning in Mice. PloS one, 11(3), e0150220. https://doi.org/10.1371/journal.pone.0150220
Chagniel, Laure, et al. "Correction: Regulation of Tyrosine Phosphatase STEP61 by Protein Kinase A during Motor Skill Learning in Mice." PloS one vol. 11,3 (2016): e0150220. doi: https://doi.org/10.1371/journal.pone.0150220
Chagniel L, Bergeron Y, Bureau G, Massicotte G, Cyr M. Correction: Regulation of Tyrosine Phosphatase STEP61 by Protein Kinase A during Motor Skill Learning in Mice. PLoS One. 2016 Mar 09;11(3):e0150220. doi: 10.1371/journal.pone.0150220. eCollection 2016. PMID: 26960137; PMCID: PMC4784932.
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Photo-thermionic effect in vertical graphene heterostructures.

Nature communications

Massicotte M, Schmidt P, Vialla F, Watanabe K, Taniguchi T, Tielrooij KJ, Koppens FH.
PMID: 27412308
Nat Commun. 2016 Jul 14;7:12174. doi: 10.1038/ncomms12174.

Finding alternative optoelectronic mechanisms that overcome the limitations of conventional semiconductor devices is paramount for detecting and harvesting low-energy photons. A highly promising approach is to drive a current from the thermal energy added to the free-electron bath as...

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Massicotte M, Schmidt P, Vialla F, et al. Photo-thermionic effect in vertical graphene heterostructures. Nat Commun. 2016;7:12174doi: 10.1038/ncomms12174.
Massicotte, M., Schmidt, P., Vialla, F., Watanabe, K., Taniguchi, T., Tielrooij, K. J., & Koppens, F. H. (2016). Photo-thermionic effect in vertical graphene heterostructures. Nature communications, 712174. https://doi.org/10.1038/ncomms12174
Massicotte, M, et al. "Photo-thermionic effect in vertical graphene heterostructures." Nature communications vol. 7 (2016): 12174. doi: https://doi.org/10.1038/ncomms12174
Massicotte M, Schmidt P, Vialla F, Watanabe K, Taniguchi T, Tielrooij KJ, Koppens FH. Photo-thermionic effect in vertical graphene heterostructures. Nat Commun. 2016 Jul 14;7:12174. doi: 10.1038/ncomms12174. PMID: 27412308; PMCID: PMC4947168.
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Comparison between Flow Cytometry and Traditional Culture Methods for Efficacy Assessment of Six Disinfectant Agents against Nosocomial Bacterial Species.

Frontiers in microbiology

Massicotte R, Mafu AA, Ahmad D, Deshaies F, Pichette G, Belhumeur P.
PMID: 28217115
Front Microbiol. 2017 Feb 03;8:112. doi: 10.3389/fmicb.2017.00112. eCollection 2017.

The present study was undertaken to compare the use of flow cytometry (FCM) and traditional culture methods for efficacy assessment of six disinfectants used in Quebec hospitals including: two quaternary ammonium-based, two activated hydrogen peroxide-based, one phenol-based, and one...

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Massicotte R, Mafu AA, Ahmad D, et al. Comparison between Flow Cytometry and Traditional Culture Methods for Efficacy Assessment of Six Disinfectant Agents against Nosocomial Bacterial Species. Front Microbiol. 2017;8:112doi: 10.3389/fmicb.2017.00112.
Massicotte, R., Mafu, A. A., Ahmad, D., Deshaies, F., Pichette, G., & Belhumeur, P. (2017). Comparison between Flow Cytometry and Traditional Culture Methods for Efficacy Assessment of Six Disinfectant Agents against Nosocomial Bacterial Species. Frontiers in microbiology, 8112. https://doi.org/10.3389/fmicb.2017.00112
Massicotte, Richard, et al. "Comparison between Flow Cytometry and Traditional Culture Methods for Efficacy Assessment of Six Disinfectant Agents against Nosocomial Bacterial Species." Frontiers in microbiology vol. 8 (2017): 112. doi: https://doi.org/10.3389/fmicb.2017.00112
Massicotte R, Mafu AA, Ahmad D, Deshaies F, Pichette G, Belhumeur P. Comparison between Flow Cytometry and Traditional Culture Methods for Efficacy Assessment of Six Disinfectant Agents against Nosocomial Bacterial Species. Front Microbiol. 2017 Feb 03;8:112. doi: 10.3389/fmicb.2017.00112. eCollection 2017. PMID: 28217115; PMCID: PMC5289957.
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Global distribution of dissolved organic matter along the aquatic continuum: Across rivers, lakes and oceans.

The Science of the total environment

Massicotte P, Asmala E, Stedmon C, Markager S.
PMID: 28738200
Sci Total Environ. 2017 Dec 31;609:180-191. doi: 10.1016/j.scitotenv.2017.07.076. Epub 2017 Jul 26.

Based on an extensive literature survey containing more than 12,000 paired measurements of dissolved organic carbon (DOC) concentrations and absorption of chromophoric dissolved organic matter (CDOM) distributed over four continents and seven oceans, we described the global distribution and...

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Massicotte P, Asmala E, Stedmon C, et al. Global distribution of dissolved organic matter along the aquatic continuum: Across rivers, lakes and oceans. Sci Total Environ. 2017;609:180-191doi: 10.1016/j.scitotenv.2017.07.076.
Massicotte, P., Asmala, E., Stedmon, C., & Markager, S. (2017). Global distribution of dissolved organic matter along the aquatic continuum: Across rivers, lakes and oceans. The Science of the total environment, 609180-191. https://doi.org/10.1016/j.scitotenv.2017.07.076
Massicotte, Philippe, et al. "Global distribution of dissolved organic matter along the aquatic continuum: Across rivers, lakes and oceans." The Science of the total environment vol. 609 (2017): 180-191. doi: https://doi.org/10.1016/j.scitotenv.2017.07.076
Massicotte P, Asmala E, Stedmon C, Markager S. Global distribution of dissolved organic matter along the aquatic continuum: Across rivers, lakes and oceans. Sci Total Environ. 2017 Dec 31;609:180-191. doi: 10.1016/j.scitotenv.2017.07.076. Epub 2017 Jul 26. PMID: 28738200.
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A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Type and Timing of Anticoagulant Thromboprophylaxis.

Global spine journal

Fehlings MG, Tetreault LA, Aarabi B, Anderson P, Arnold PM, Brodke DS, Burns AS, Chiba K, Dettori JR, Furlan JC, Hawryluk G, Holly LT, Howley S, Jeji T, Kalsi-Ryan S, Kotter M, Kurpad S, Kwon BK, Marino RJ, Martin AR, Massicotte E, Merli G, Middleton JW, Nakashima H, Nagoshi N, Palmieri K, Singh A, Skelly AC, Tsai EC, Vaccaro A, Wilson JR, Yee A, Harrop JS.
PMID: 29164026
Global Spine J. 2017 Sep;7(3):212S-220S. doi: 10.1177/2192568217702107. Epub 2017 Sep 05.

INTRODUCTION: The objective of this study is to develop evidence-based guidelines that recommend effective, safe and cost-effective thromboprophylaxis strategies in patients with spinal cord injury (SCI).METHODS: A systematic review of the literature was conducted to address key questions relating...

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Fehlings MG, Tetreault LA, Aarabi B, et al. A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Type and Timing of Anticoagulant Thromboprophylaxis. Global Spine J. 2017;7(3):212S-220Sdoi: 10.1177/2192568217702107.
Fehlings, M. G., Tetreault, L. A., Aarabi, B., Anderson, P., Arnold, P. M., Brodke, D. S., Burns, A. S., Chiba, K., Dettori, J. R., Furlan, J. C., Hawryluk, G., Holly, L. T., Howley, S., Jeji, T., Kalsi-Ryan, S., Kotter, M., Kurpad, S., Kwon, B. K., Marino, R. J., Martin, A. R., Massicotte, E., Merli, G., Middleton, J. W., Nakashima, H., Nagoshi, N., Palmieri, K., Singh, A., Skelly, A. C., Tsai, E. C., Vaccaro, A., Wilson, J. R., Yee, A., & Harrop, J. S. (2017). A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Type and Timing of Anticoagulant Thromboprophylaxis. Global spine journal, 7(3), 212S-220S. https://doi.org/10.1177/2192568217702107
Fehlings, Michael G, et al. "A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Type and Timing of Anticoagulant Thromboprophylaxis." Global spine journal vol. 7,3 (2017): 212S-220S. doi: https://doi.org/10.1177/2192568217702107
Fehlings MG, Tetreault LA, Aarabi B, Anderson P, Arnold PM, Brodke DS, Burns AS, Chiba K, Dettori JR, Furlan JC, Hawryluk G, Holly LT, Howley S, Jeji T, Kalsi-Ryan S, Kotter M, Kurpad S, Kwon BK, Marino RJ, Martin AR, Massicotte E, Merli G, Middleton JW, Nakashima H, Nagoshi N, Palmieri K, Singh A, Skelly AC, Tsai EC, Vaccaro A, Wilson JR, Yee A, Harrop JS. A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Type and Timing of Anticoagulant Thromboprophylaxis. Global Spine J. 2017 Sep;7(3):212S-220S. doi: 10.1177/2192568217702107. Epub 2017 Sep 05. PMID: 29164026; PMCID: PMC5684841.
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Consensus statement: Hemostasis trial outcomes in cardiac surgery/mechanical support.

The Annals of thoracic surgery

Levy JH, Faraoni D, Almond CS, Baumann-Kreuziger L, Bembea MM, Connors JM, Dalton HJ, Davies R, Dumont LJ, Griselli M, Karkouti K, Massicotte MP, Teruya J, Thiagarajan RR, Spinella PC, Steiner ME.
PMID: 34826386
Ann Thorac Surg. 2021 Nov 23; doi: 10.1016/j.athoracsur.2021.09.080. Epub 2021 Nov 23.

BACKGROUND: Research evaluating hemostatic agents for the treatment of clinically significant bleeding has been hampered by inconsistency and lack of standardized primary clinical trial outcomes. Clinical trials of hemostatic agents in both cardiac surgery and mechanical circulatory support (MCS),...

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Levy JH, Faraoni D, Almond CS, et al. Consensus statement: Hemostasis trial outcomes in cardiac surgery/mechanical support. Ann Thorac Surg. 2021;doi: 10.1016/j.athoracsur.2021.09.080.
Levy, J. H., Faraoni, D., Almond, C. S., Baumann-Kreuziger, L., Bembea, M. M., Connors, J. M., Dalton, H. J., Davies, R., Dumont, L. J., Griselli, M., Karkouti, K., Massicotte, M. P., Teruya, J., Thiagarajan, R. R., Spinella, P. C., & Steiner, M. E. (2021). Consensus statement: Hemostasis trial outcomes in cardiac surgery/mechanical support. The Annals of thoracic surgery, . https://doi.org/10.1016/j.athoracsur.2021.09.080
Levy, Jerrold H, et al. "Consensus statement: Hemostasis trial outcomes in cardiac surgery/mechanical support." The Annals of thoracic surgery vol. (2021). doi: https://doi.org/10.1016/j.athoracsur.2021.09.080
Levy JH, Faraoni D, Almond CS, Baumann-Kreuziger L, Bembea MM, Connors JM, Dalton HJ, Davies R, Dumont LJ, Griselli M, Karkouti K, Massicotte MP, Teruya J, Thiagarajan RR, Spinella PC, Steiner ME. Consensus statement: Hemostasis trial outcomes in cardiac surgery/mechanical support. Ann Thorac Surg. 2021 Nov 23; doi: 10.1016/j.athoracsur.2021.09.080. Epub 2021 Nov 23. PMID: 34826386.
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Hot carriers in graphene - fundamentals and applications.

Nanoscale

Massicotte M, Soavi G, Principi A, Tielrooij KJ.
PMID: 33913956
Nanoscale. 2021 May 14;13(18):8376-8411. doi: 10.1039/d0nr09166a. Epub 2021 Apr 29.

Hot charge carriers in graphene exhibit fascinating physical phenomena, whose understanding has improved greatly over the past decade. They have distinctly different physical properties compared to, for example, hot carriers in conventional metals. This is predominantly the result of...

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Massicotte M, Soavi G, Principi A, et al. Hot carriers in graphene - fundamentals and applications. Nanoscale. 2021;13(18):8376-8411doi: 10.1039/d0nr09166a.
Massicotte, M., Soavi, G., Principi, A., & Tielrooij, K. J. (2021). Hot carriers in graphene - fundamentals and applications. Nanoscale, 13(18), 8376-8411. https://doi.org/10.1039/d0nr09166a
Massicotte, Mathieu, et al. "Hot carriers in graphene - fundamentals and applications." Nanoscale vol. 13,18 (2021): 8376-8411. doi: https://doi.org/10.1039/d0nr09166a
Massicotte M, Soavi G, Principi A, Tielrooij KJ. Hot carriers in graphene - fundamentals and applications. Nanoscale. 2021 May 14;13(18):8376-8411. doi: 10.1039/d0nr09166a. Epub 2021 Apr 29. PMID: 33913956; PMCID: PMC8118204.
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General-purpose genotype or how epigenetics extend the flexibility of a genotype.

Genetics research international

Massicotte R, Angers B.
PMID: 22567383
Genet Res Int. 2012;2012:317175. doi: 10.1155/2012/317175. Epub 2011 Dec 15.

This project aims at investigating the link between individual epigenetic variability (not related to genetic variability) and the variation of natural environmental conditions. We studied DNA methylation polymorphisms of individuals belonging to a single genetic lineage of the clonal...

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Massicotte R, Angers B. General-purpose genotype or how epigenetics extend the flexibility of a genotype. Genet Res Int. 2011;2012:317175doi: 10.1155/2012/317175.
Massicotte, R., & Angers, B. (2012). General-purpose genotype or how epigenetics extend the flexibility of a genotype. Genetics research international, 2012317175. https://doi.org/10.1155/2012/317175
Massicotte, Rachel, and Angers, Bernard. "General-purpose genotype or how epigenetics extend the flexibility of a genotype." Genetics research international vol. 2012 (2012): 317175. doi: https://doi.org/10.1155/2012/317175
Massicotte R, Angers B. General-purpose genotype or how epigenetics extend the flexibility of a genotype. Genet Res Int. 2012;2012:317175. doi: 10.1155/2012/317175. Epub 2011 Dec 15. PMID: 22567383; PMCID: PMC3335555.
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