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Showing 1 to 12 of 25 entries
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Ceftolozane/Tazobactam for Treatment of Severe ESBL-Producing .

Open forum infectious diseases

Bassetti M, Vena A, Giacobbe DR, Falcone M, Tiseo G, Giannella M, Pascale R, Meschiari M, Digaetano M, Oliva A, Rovelli C, Carannante N, Losito AR, Carbonara S, Mariani MF, Mastroianni A, Angarano G, Tumbarello M, Tascini C, Grossi P, Mastroianni CM, Mussini C, Viale P, Menichetti F, Viscoli C, Russo A.
PMID: 32462046
Open Forum Infect Dis. 2020 Apr 21;7(5):ofaa139. doi: 10.1093/ofid/ofaa139. eCollection 2020 May.

BACKGROUND: Few data are reported in the literature about the outcome of patients with severe extended-spectrum β-lactamase-producing METHODS: A multicenter retrospective study was performed in Italy (June 2016-June 2019). Successful clinical outcome was defined as complete resolution of clinical...

A novel .

Neurology. Genetics

Alshaikh JT, Qin K, Zhao L, Mastrianni JA.
PMID: 32637633
Neurol Genet. 2020 Jun 05;6(4):e454. doi: 10.1212/NXG.0000000000000454. eCollection 2020 Aug.

No abstract available.

Subcutaneous tocilizumab treatment in patients with severe COVID-19-related cytokine release syndrome: An observational cohort study.

EClinicalMedicine

Mastroianni A, Greco S, Apuzzo G, De Santis S, Oriolo C, Zanolini A, Chidichimo L, Vangeli V.
PMID: 32766535
EClinicalMedicine. 2020 Jul 01;24:100410. doi: 10.1016/j.eclinm.2020.100410. eCollection 2020 Jul.

BACKGROUND: Patients with severe coronavirus disease 2019 (COVID-19) have elevated levels of acute phase reactants and inflammatory cytokines, including interleukin-6, indicative of cytokine release syndrome (CRS). The interleukin-6 receptor inhibitor tocilizumab is used for the treatment of chimeric antigen...

Impaired transmissibility of atypical prions from genetic CJD.

Neurology. Genetics

Cali I, Mikhail F, Qin K, Gregory C, Solanki A, Martinez MC, Zhao L, Appleby B, Gambetti P, Norstrom E, Mastrianni JA.
PMID: 30109268
Neurol Genet. 2018 Aug 07;4(4):e253. doi: 10.1212/NXG.0000000000000253. eCollection 2018 Aug.

OBJECTIVE: To describe the clinicopathologic, molecular, and transmissible characteristics of genetic prion disease in a young man carrying the METHODS: We performed genetic, histologic, and molecular studies, combined with in vivo transmission studies and in vitro replication studies, to...

[Septic arthritis in the setting of HIV disease. A case report and literature review].

Le infezioni in medicina

Manfredi R, Legnani G, Mastroianni A, Coronado OV, Chiodo F.
PMID: 12847313
Infez Med. 1997 Mar;5(1):52-6.

A case of septic arthritis due to Haemophilus influenzae is described in a HIV-infected patient. Even though complicated by large effusion and extensive subcutaneous involvement, the clinical picture showed a favourable outcome after prolonged ceftriaxone treatment, leading to complete...

[Bacteraemia in patients with HIV disease: aetiological spectrum and profile of antimicrobial susceptibility].

Le infezioni in medicina

Manfredi R, Nanetti A, Ferri M, Mastroianni A, Coronado OV, Chiodo F.
PMID: 12847308
Infez Med. 1997 Mar;5(1):23-8.

A retrospective survey of non-opportunistic bacterial pathogens isolated from blood cultures of patients with HIV disease has been carried out for a 6-year period, and the antibiotic susceptibility of the 748 microorganisms cultured from 682 consecutive patients, has been...

Early use of canakinumab to prevent mechanical ventilation in select COVID-19 patients: A retrospective, observational analysis.

International journal of immunopathology and pharmacology

Mastroianni A, Greco S, Chidichimo L, Urso F, Greco F, Mauro MV, Vangeli V.
PMID: 34928722
Int J Immunopathol Pharmacol. 2021 Jan-Dec;35:20587384211059675. doi: 10.1177/20587384211059675.

INTRODUCTION: The fully-human monoclonal anti-interleukin (IL)-1β antibody canakinumab may inhibit the production of inflammatory mediators in patients with coronavirus disease 2019 (COVID-19) and the hyperinflammatory response potentially leading to acute respiratory distress syndrome.OBJECTIVES: The goal of our retrospective, observational...

Treatment Rechallenge With Checkpoint Inhibition in Patients With Mismatch Repair-Deficient Pancreatic Cancer After Planned Treatment Interruption.

JCO precision oncology

Florou V, Nevala-Plagemann C, Barber KE, Mastroianni JN, Cavalieri CC, Garrido-Laguna I.
PMID: 33542969
JCO Precis Oncol. 2020 Jun 30;4. doi: 10.1200/PO.20.00052. eCollection 2020.

No abstract available.

Differential Susceptibility of Bacteria to Mouse Paneth Cell α-Defensins under Anaerobic Conditions.

Antibiotics (Basel, Switzerland)

Mastroianni JR, Lu W, Selsted ME, Ouellette AJ.
PMID: 25383215
Antibiotics (Basel). 2014;3(4):493-508. doi: 10.3390/antibiotics3040493.

Small intestinal Paneth cells secrete α-defensin peptides, termed cryptdins (Crps) in mice, into the intestinal lumen, where they confer immunity to oral infections and define the composition of the ileal microbiota. In these studies, facultative bacteria maintained under aerobic...

Ochrobactrum anthropi bacteremia: case report and review of the literature.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Mastroianni A, Cancellieri C, Montini G.
PMID: 11851711
Clin Microbiol Infect. 1999 Sep;5(9):570-573. doi: 10.1111/j.1469-0691.1999.tb00437.x.

No abstract available.

Early Delivery of Misfolded PrP from ER to Lysosomes by Autophagy.

International journal of cell biology

Cortes CJ, Qin K, Norstrom EM, Green WN, Bindokas VP, Mastrianni JA.
PMID: 24454378
Int J Cell Biol. 2013;2013:560421. doi: 10.1155/2013/560421. Epub 2013 Dec 17.

Prion diseases are linked to the accumulation of a misfolded isoform (PrP(Sc)) of prion protein (PrP). Evidence suggests that lysosomes are degradation endpoints and sites of the accumulation of PrP(Sc). We questioned whether lysosomes participate in the early quality...

Correction for Cobo et al., "Entamoeba histolytica Alters Ileal Paneth Cell Functions in Intact and Muc2 Mucin Deficiency".

Infection and immunity

Cobo ER, Holani R, Moreau F, Nakamura K, Ayabe T, Mastroianni JR, Eriguchi Y, Ouellette A, Chadee K.
PMID: 30242014
Infect Immun. 2018 Sep 21;86(10). doi: 10.1128/IAI.00564-18. Print 2018 Oct.

No abstract available.

Showing 1 to 12 of 25 entries