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Showing 1 to 12 of 12 entries
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A liquid-crystalline hexagonal columnar phase in highly-dilute suspensions of imogolite nanotubes.

Nature communications

Paineau E, Krapf ME, Amara MS, Matskova NV, Dozov I, Rouzière S, Thill A, Launois P, Davidson P.
PMID: 26728415
Nat Commun. 2016 Jan 05;7:10271. doi: 10.1038/ncomms10271.

Liquid crystals have found wide applications in many fields ranging from detergents to information displays and they are also increasingly being used in the 'bottom-up' self-assembly approach of material nano-structuration. Moreover, liquid-crystalline organizations are frequently observed by biologists. Here...

Spatial Navigation and Visuospatial Strategies in Typical and Atypical Aging.

Brain sciences

Laczó M, Wiener JM, Kalinova J, Matuskova V, Vyhnalek M, Hort J, Laczó J.
PMID: 34827423
Brain Sci. 2021 Oct 27;11(11). doi: 10.3390/brainsci11111421.

Age-related spatial navigation decline is more pronounced in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) dementia. We used a realistic-looking virtual navigation test suite to analyze different aspects of visuospatial processing in typical and atypical aging....

Results of Ranibizumab Treatment of the Myopic Choroidal Neovascular Membrane according to the Axial Length of the Eye.

Journal of ophthalmology

Stepanov A, Pencak M, Nemcansky J, Matuskova V, Stredova M, Beran D, Studnicka J.
PMID: 32454987
J Ophthalmol. 2020 May 12;2020:3076596. doi: 10.1155/2020/3076596. eCollection 2020.

AIM: A retrospective evaluation of the results of treatment of myopic choroidal neovascularization (mCNV) with intravitreal injections of ranibizumab in a METHODS: The paper presents a retrospective multicenter study carried out with the cooperation of several Departments of Ophthalmology...

Epigenetic inactivation of hydroxymethylglutaryl CoA synthase reduces ketogenesis and facilitates tumor cell motility in clear cell renal carcinoma.

Pathology, research and practice

Han P, Wang Y, Luo W, Lu Y, Zhou X, Yang Y, Zheng Q, Li D, Wu S, Li L, Zhang H, Zhao J, Zhang Z, Matskova L, Li P, Zhou X.
PMID: 34624592
Pathol Res Pract. 2021 Nov;227:153622. doi: 10.1016/j.prp.2021.153622. Epub 2021 Sep 20.

Previously, we have reported that the dysregulation of ketogenesis plays an important role in the carcinogenesis of clear cell renal cell carcinoma (ccRCC). Here, we demonstrate decreased expression of the HMGCS2 gene in ccRCC, a critical enzyme for the...

Epstein-Barr virus-encoded LMP2A stimulates migration of nasopharyngeal carcinoma cells via the EGFR/Ca.

Biology open

Liang J, Zheng S, Xiao X, Wei J, Zhang Z, Ernberg I, Matskova L, Huang G, Zhou X.
PMID: 28512118
Biol Open. 2017 Jun 15;6(6):914-922. doi: 10.1242/bio.024646.

Epstein-Barr virus (EBV)-encoded latent membrane protein 2A (LMP2A) promotes the motility of nasopharyngeal carcinoma (NPC) cells. Previously, we have shown that the localization of integrin β4 (ITGβ4) is regulated by LMP2A, with ITGβ4 concentrated at the cellular protrusions in...

Dysregulation of Ketone Body Metabolism Is Associated With Poor Prognosis for Clear Cell Renal Cell Carcinoma Patients.

Frontiers in oncology

Cui W, Luo W, Zhou X, Lu Y, Xu W, Zhong S, Feng G, Liang Y, Liang L, Mo Y, Xiao X, Huang G, Matskova L, Zhang Z, Li P, Zhou X.
PMID: 31921677
Front Oncol. 2019 Dec 17;9:1422. doi: 10.3389/fonc.2019.01422. eCollection 2019.

Kidney is an important organ for ketone body metabolism. However, the role of abnormal ketone metabolism and its possible function in tumorigenesis of clear cell renal cell carcinoma (ccRCC) have not yet been elucidated. Three differentially expressed key enzymes...

Memory Binding Test and Its Associations With Hippocampal Volume Across the Cognitive Continuum Preceding Dementia.

Assessment

Markova H, Fendrych Mazancova A, Jester DJ, Cechova K, Matuskova V, Nikolai T, Nedelska Z, Uller M, Andel R, Laczó J, Hort J, Vyhnalek M.
PMID: 35023365
Assessment. 2022 Jan 13;10731911211069676. doi: 10.1177/10731911211069676. Epub 2022 Jan 13.

Innovative memory paradigms have been introduced to capture subtle memory changes in early Alzheimer's disease (AD). We aimed to examine the associations between different indexes of the challenging Memory Binding Test (MBT) and hippocampal volume (HV) in a sample...

Epigenetic inactivation of ACAT1 promotes epithelial-mesenchymal transition of clear cell renal cell carcinoma.

Genes & genomics

Han P, Wu S, Li L, Li D, Zhao J, Zhang H, Wang Y, Zhong X, Zhang Z, Li P, Matskova L, Zhou X.
PMID: 34985712
Genes Genomics. 2022 Jan 05; doi: 10.1007/s13258-021-01211-y. Epub 2022 Jan 05.

BACKGROUND: Acetyl-CoA acyltransferase 1 (ACAT1) is a key enzyme catalyzing the production of mitochondrial ketone bodies. We have shown that ACAT1 is down-regulated in kidney renal clear cell carcinoma (KIRC) previously.OBJECTIVE: To investigate the reasons for downregulation of ACAT1...

Anti-conjunctivitis effect of fresh juice of xGraptoveria (Crassulaceae): A phytochemical and ethnobotanical study.

Journal of intercultural ethnopharmacology

Markova NV, Batovska DI, Kozuharova EK, Enchev VG.
PMID: 26401380
J Intercult Ethnopharmacol. 2015 Jan-Mar;4(1):24-8. doi: 10.5455/jice.20141104014605. Epub 2014 Nov 28.

AIM: The parent of xGraptoveria, Graptopetalum paraguayense, is used in Chinese folk medicine for alleviating hepatic disorders, detumescence and detoxication, lowering of blood pressure, inhibition of cancer cells, exerting diuretic effects, relieving pain and infections. No data are available...

Genetic damage in lymphocytes of lung cancer patients is correlated to the composition of the respiratory tract microbiome.

Mutagenesis

Druzhinin VG, Matskova LV, Demenkov PS, Baranova ED, Volobaev VP, Minina VI, Larionov AV, Titov VA, Fucic A.
PMID: 33454779
Mutagenesis. 2021 May 31;36(2):143-153. doi: 10.1093/mutage/geab004.

Recent findings indicate that the microbiome may have significant impact on the development of lung cancer by its effects on inflammation, dysbiosis or genome damage. The aim of this study was to compare the sputum microbiome of lung cancer...

Mild Behavioral Impairment Is Associated With Atrophy of Entorhinal Cortex and Hippocampus in a Memory Clinic Cohort.

Frontiers in aging neuroscience

Matuskova V, Ismail Z, Nikolai T, Markova H, Cechova K, Nedelska Z, Laczo J, Wang M, Hort J, Vyhnalek M.
PMID: 34108874
Front Aging Neurosci. 2021 May 24;13:643271. doi: 10.3389/fnagi.2021.643271. eCollection 2021.

OBJECTIVES: Mild behavioral impairment (MBI) is a syndrome describing late-onset persistent neuropsychiatric symptoms (NPS) in non-demented older adults. Few studies to date have investigated the associations of MBI with structural brain changes. Our aim was to explore structural correlates...

Biosimilar SB11 versus reference ranibizumab in neovascular age-related macular degeneration: 1-year phase III randomised clinical trial outcomes.

The British journal of ophthalmology

Bressler NM, Veith M, Hamouz J, Ernest J, Zalewski D, Studnička J, Vajas A, Papp A, Vogt G, Luu J, Matuskova V, Yoon YH, Pregun T, Kim T, Shin D, Oh I, Jeong H, Kim MY, Woo SJ.
PMID: 34656987
Br J Ophthalmol. 2021 Oct 16; doi: 10.1136/bjophthalmol-2021-319637. Epub 2021 Oct 16.

INTERVENTION: 1:1 randomisation to monthly intravitreal injection of 0.5 mg SB11 or RBZ. RESULTS: Baseline and disease characteristics were comparable between treatment groups. Of 705 randomised participants (SB11: n=351; RBZ: n=354), 634 participants (89.9%; SB11: n=307; RBZ: n=327) completed...

Showing 1 to 12 of 12 entries