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Showing 1 to 12 of 42 entries
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In-patient physiotherapy for adults on veno-venous extracorporeal membrane oxygenation - United Kingdom ECMO Physiotherapy Network: A consensus agreement for best practice.

Journal of the Intensive Care Society

Eden A, Purkiss C, Cork G, Baddeley A, Morris K, Carey L, Brown M, McGarrigle L, Kennedy S.
PMID: 29118833
J Intensive Care Soc. 2017 Aug;18(3):212-220. doi: 10.1177/1751143717705801. Epub 2017 Jun 14.

Clinical specialist physiotherapists from the five severe respiratory failure centres in England where respiratory extracorporeal membrane oxygenation (ECMO) is practiced have established this consensus agreement for physiotherapy best practice. The severe respiratory failure centres are Wythenshawe Hospital, Manchester; Glenfield...

Investigation of RadFET response to X-ray and electron beams.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

Yilmaz E, Kahraman A, McGarrigle AM, Vasovic N, Yegen D, Jaksic A.
PMID: 28622597
Appl Radiat Isot. 2017 Sep;127:156-160. doi: 10.1016/j.apradiso.2017.06.004. Epub 2017 Jun 08.

The irradiation response of Radiation Sensing Field Effect Transistor (RadFET), also known as MOSFET/pMOS dosimeter, to high energy X-rays and electron beams was investigated. The threshold voltages before and after irradiation were measured and the trap densities in the...

Stereoselective organocatalyzed glycosylations - thiouracil, thioureas and monothiophthalimide act as Brønsted acid catalysts at low loadings.

Chemical science

Bradshaw GA, Colgan AC, Allen NP, Pongener I, Boland MB, Ortin Y, McGarrigle EM.
PMID: 30713648
Chem Sci. 2018 Oct 22;10(2):508-514. doi: 10.1039/c8sc02788a. eCollection 2019 Jan 14.

Thiouracil catalyzes stereoselective glycosylations with galactals in loadings as low as 0.1 mol%. It is proposed that in these glycosylations thiouracil, monothiophthalimide, and the previously reported catalyst, Schreiner's thiourea, do not operate

Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering.

Cell reports

Hamilton JR, Tsuchida CA, Nguyen DN, Shy BR, McGarrigle ER, Sandoval Espinoza CR, Carr D, Blaeschke F, Marson A, Doudna JA.
PMID: 34077734
Cell Rep. 2021 Jun 01;35(9):109207. doi: 10.1016/j.celrep.2021.109207.

As genome engineering advances cell-based therapies, a versatile approach to introducing both CRISPR-Cas9 ribonucleoproteins (RNPs) and therapeutic transgenes into specific cells would be transformative. Autologous T cells expressing a chimeric antigen receptor (CAR) manufactured by viral transduction are approved...

Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering.

Cell reports

Hamilton JR, Tsuchida CA, Nguyen DN, Shy BR, McGarrigle ER, Sandoval Espinoza CR, Carr D, Blaeschke F, Marson A, Doudna JA.
PMID: 34077734
Cell Rep. 2021 Jun 01;35(9):109207. doi: 10.1016/j.celrep.2021.109207.

As genome engineering advances cell-based therapies, a versatile approach to introducing both CRISPR-Cas9 ribonucleoproteins (RNPs) and therapeutic transgenes into specific cells would be transformative. Autologous T cells expressing a chimeric antigen receptor (CAR) manufactured by viral transduction are approved...

Predictors of Listening-Related Fatigue Across the Adult Life Span.

Psychological science

McGarrigle R, Knight S, Hornsby BWY, Mattys S.
PMID: 34751602
Psychol Sci. 2021 Nov 09;9567976211016410. doi: 10.1177/09567976211016410. Epub 2021 Nov 09.

Listening-related fatigue is a potentially serious negative consequence of an aging auditory and cognitive system. However, the impact of age on listening-related fatigue and the factors underpinning any such effect remain unexplored. Using data from a large sample of...

Non-contrast CT at comparable dose to an abdominal radiograph in patients with acute renal colic; impact of iterative reconstruction on image quality and diagnostic performance.

Insights into imaging

McLaughlin PD, Murphy KP, Hayes SA, Carey K, Sammon J, Crush L, O'Neill F, Normoyle B, McGarrigle AM, Barry JE, Maher MM.
PMID: 24500656
Insights Imaging. 2014 Apr;5(2):217-30. doi: 10.1007/s13244-014-0310-z. Epub 2014 Feb 07.

OBJECTIVES: The aim was to assess the performance of low-dose non-contrast CT of the urinary tract (LD-CT) acquired at radiation exposures close to that of abdominal radiography using adaptive statistical iterative reconstruction (ASiR).METHODS: Thirty-three patients with clinically suspected renal...

Chalcogenides as organocatalysts.

Chemical reviews

McGarrigle EM, Myers EL, Illa O, Shaw MA, Riches SL, Aggarwal VK.
PMID: 18072810
Chem Rev. 2007 Dec;107(12):5841-83. doi: 10.1021/cr068402y.

No abstract available.

Synthesis and application of easily recyclable thiomorpholines for use in sulfur ylide mediated asymmetric epoxidation of aldehydes.

Chemistry, an Asian journal

Hansch M, Illa O, McGarrigle EM, Aggarwal VK.
PMID: 18604816
Chem Asian J. 2008 Sep 01;3(8):1657-63. doi: 10.1002/asia.200800174.

Chiral nonracemic thiomorpholines have been synthesized in four to six steps from limonene or achiral alkenes using alpha-methylbenzylamine to control absolute stereochemistry. These aminosulfides have been used to generate sulfur ylides, which have been applied in the asymmetric epoxidation...

Synthesis of P-stereogenic phosphorus compounds. Asymmetric oxidation of phosphines under Appel conditions.

Journal of the American Chemical Society

Bergin E, O'Connor CT, Robinson SB, McGarrigle EM, O'Mahony CP, Gilheany DG.
PMID: 17630743
J Am Chem Soc. 2007 Aug 08;129(31):9566-7. doi: 10.1021/ja072925l. Epub 2007 Jul 14.

No abstract available.

Structural changes in alginate-based microspheres exposed to in vivo environment as revealed by confocal Raman microscopy.

Scientific reports

Kroneková Z, Pelach M, Mazancová P, Uhelská L, Treľová D, Rázga F, Némethová V, Szalai S, Chorvát D, McGarrigle JJ, Omami M, Isa D, Ghani S, Majková E, Oberholzer J, Raus V, Šiffalovič P, Lacík I.
PMID: 29374272
Sci Rep. 2018 Jan 26;8(1):1637. doi: 10.1038/s41598-018-20022-y.

A next-generation cure for type 1 diabetes relies on immunoprotection of insulin-producing cells, which can be achieved by their encapsulation in microspheres made of non-covalently crosslinked hydrogels. Treatment success is directly related to the microsphere structure that is characterized...

Stereoselective β-mannosylations and β-rhamnosylations from glycosyl hemiacetals mediated by lithium iodide.

Chemical science

Pongener I, Pepe DA, Ruddy JJ, McGarrigle EM.
PMID: 34377400
Chem Sci. 2021 Jul 05;12(29):10070-10075. doi: 10.1039/d1sc01300a. eCollection 2021 Jul 28.

Stereoselective β-mannosylation is one of the most challenging problems in the synthesis of oligosaccharides. Herein, a highly selective synthesis of β-mannosides and β-rhamnosides from glycosyl hemi-acetals is reported, following a one-pot chlorination, iodination, glycosylation sequence employing cheap oxalyl chloride,...

Showing 1 to 12 of 42 entries