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Showing 1 to 12 of 23 entries
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Interferon-γ from Brain Leukocytes Enhances Meningitis by Type 4 Streptococcus pneumoniae.

Frontiers in microbiology

Pettini E, Fiorino F, Cuppone AM, Iannelli F, Medaglini D, Pozzi G.
PMID: 26648922
Front Microbiol. 2015 Dec 01;6:1340. doi: 10.3389/fmicb.2015.01340. eCollection 2015.

Streptococcus pneumoniae is the leading cause of bacterial meningitis. Pneumococcal meningitis is a life-threatening disease with high rates of mortality and neurological sequelae. Immune targeting of S. pneumoniae is essential for clearance of infection; however, within the brain, the...

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Pettini E, Fiorino F, Cuppone AM, et al. Interferon-γ from Brain Leukocytes Enhances Meningitis by Type 4 Streptococcus pneumoniae. Front Microbiol. 2015;6:1340doi: 10.3389/fmicb.2015.01340.
Pettini, E., Fiorino, F., Cuppone, A. M., Iannelli, F., Medaglini, D., & Pozzi, G. (2015). Interferon-γ from Brain Leukocytes Enhances Meningitis by Type 4 Streptococcus pneumoniae. Frontiers in microbiology, 61340. https://doi.org/10.3389/fmicb.2015.01340
Pettini, Elena, et al. "Interferon-γ from Brain Leukocytes Enhances Meningitis by Type 4 Streptococcus pneumoniae." Frontiers in microbiology vol. 6 (2015): 1340. doi: https://doi.org/10.3389/fmicb.2015.01340
Pettini E, Fiorino F, Cuppone AM, Iannelli F, Medaglini D, Pozzi G. Interferon-γ from Brain Leukocytes Enhances Meningitis by Type 4 Streptococcus pneumoniae. Front Microbiol. 2015 Dec 01;6:1340. doi: 10.3389/fmicb.2015.01340. eCollection 2015. PMID: 26648922; PMCID: PMC4664635.
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Using IFN-gamma release assay to confirm tuberculin skin test improves the screening of latent tuberculosis infection in Italian healthcare workers.

Journal of occupational medicine and toxicology (London, England)

Olivieri R, Scarnera S, Ciabattini A, De Vuono G, Manzi P, Pozzi G, Battista G, Medaglini D.
PMID: 27279894
J Occup Med Toxicol. 2016 Jun 07;11:29. doi: 10.1186/s12995-016-0117-6. eCollection 2016.

BACKGROUND: Healthcare workers (HCWs) represent a tuberculosis (TB) risk group for a wide range of tasks in healthcare, even in countries with low TB incidence, like Italy. Latent Tuberculosis Infection (LTBI) screening programs are an important tool for TB...

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Olivieri R, Scarnera S, Ciabattini A, et al. Using IFN-gamma release assay to confirm tuberculin skin test improves the screening of latent tuberculosis infection in Italian healthcare workers. J Occup Med Toxicol. 2016;11:29doi: 10.1186/s12995-016-0117-6.
Olivieri, R., Scarnera, S., Ciabattini, A., De Vuono, G., Manzi, P., Pozzi, G., Battista, G., & Medaglini, D. (2016). Using IFN-gamma release assay to confirm tuberculin skin test improves the screening of latent tuberculosis infection in Italian healthcare workers. Journal of occupational medicine and toxicology (London, England), 1129. https://doi.org/10.1186/s12995-016-0117-6
Olivieri, Raffaela, et al. "Using IFN-gamma release assay to confirm tuberculin skin test improves the screening of latent tuberculosis infection in Italian healthcare workers." Journal of occupational medicine and toxicology (London, England) vol. 11 (2016): 29. doi: https://doi.org/10.1186/s12995-016-0117-6
Olivieri R, Scarnera S, Ciabattini A, De Vuono G, Manzi P, Pozzi G, Battista G, Medaglini D. Using IFN-gamma release assay to confirm tuberculin skin test improves the screening of latent tuberculosis infection in Italian healthcare workers. J Occup Med Toxicol. 2016 Jun 07;11:29. doi: 10.1186/s12995-016-0117-6. eCollection 2016. PMID: 27279894; PMCID: PMC4897955.
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CD4(+) T Cell Priming as Biomarker to Study Immune Response to Preventive Vaccines.

Frontiers in immunology

Ciabattini A, Pettini E, Medaglini D.
PMID: 24363656
Front Immunol. 2013 Dec 04;4:421. doi: 10.3389/fimmu.2013.00421.

T cell priming is a critical event in the initiation of the immune response to vaccination since it deeply influences both the magnitude and the quality of the immune response induced. CD4(+) T cell priming, required for the induction...

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Ciabattini A, Pettini E, Medaglini D. CD4(+) T Cell Priming as Biomarker to Study Immune Response to Preventive Vaccines. Front Immunol. 2013;4:421doi: 10.3389/fimmu.2013.00421.
Ciabattini, A., Pettini, E., & Medaglini, D. (2013). CD4(+) T Cell Priming as Biomarker to Study Immune Response to Preventive Vaccines. Frontiers in immunology, 4421. https://doi.org/10.3389/fimmu.2013.00421
Ciabattini, Annalisa, et al. "CD4(+) T Cell Priming as Biomarker to Study Immune Response to Preventive Vaccines." Frontiers in immunology vol. 4 (2013): 421. doi: https://doi.org/10.3389/fimmu.2013.00421
Ciabattini A, Pettini E, Medaglini D. CD4(+) T Cell Priming as Biomarker to Study Immune Response to Preventive Vaccines. Front Immunol. 2013 Dec 04;4:421. doi: 10.3389/fimmu.2013.00421. PMID: 24363656; PMCID: PMC3850413.
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Impact of interproximal composite restorations on periodontal tissue health: Clinical and cytokine profiles from a pre-post quasi-experimental study.

Journal of periodontology

Nicola D, Crystal M, Francesco S, Raffaele M, Fiorino F, Donata M, Gianni P, Marco F, Simone G.
PMID: 34453748
J Periodontol. 2021 Aug 28; doi: 10.1002/JPER.21-0219. Epub 2021 Aug 28.

BACKGROUND: The aim of this study is to clinically and molecularly evaluate the effect of an interproximal iuxta/subgingival direct composite restoration on periodontal tissue healing.METHODS: Individuals in need of a posterior iuxta/subgingival interproximal restoration were consecutively enrolled. After enrollment,...

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Nicola D, Crystal M, Francesco S, et al. Impact of interproximal composite restorations on periodontal tissue health: Clinical and cytokine profiles from a pre-post quasi-experimental study. J Periodontol. 2021;doi: 10.1002/JPER.21-0219.
Nicola, D., Crystal, M., Francesco, S., Raffaele, M., Fiorino, F., Donata, M., Gianni, P., Marco, F., & Simone, G. (2021). Impact of interproximal composite restorations on periodontal tissue health: Clinical and cytokine profiles from a pre-post quasi-experimental study. Journal of periodontology, . https://doi.org/10.1002/JPER.21-0219
Nicola, Discepoli, et al. "Impact of interproximal composite restorations on periodontal tissue health: Clinical and cytokine profiles from a pre-post quasi-experimental study." Journal of periodontology vol. (2021). doi: https://doi.org/10.1002/JPER.21-0219
Nicola D, Crystal M, Francesco S, Raffaele M, Fiorino F, Donata M, Gianni P, Marco F, Simone G. Impact of interproximal composite restorations on periodontal tissue health: Clinical and cytokine profiles from a pre-post quasi-experimental study. J Periodontol. 2021 Aug 28; doi: 10.1002/JPER.21-0219. Epub 2021 Aug 28. PMID: 34453748.
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Metachromatic leukodystrophy: A single-center longitudinal study of 45 patients.

Journal of inherited metabolic disease

Fumagalli F, Zambon AA, Rancoita PMV, Baldoli C, Canale S, Spiga I, Medaglini S, Penati R, Facchini M, Ciotti F, Sarzana M, Lorioli L, Cesani M, Natali Sora MG, Del Carro U, Cugnata F, Antonioli G, Recupero S, Calbi V, Di Serio C, Aiuti A, Biffi A, Sessa M.
PMID: 33855715
J Inherit Metab Dis. 2021 Sep;44(5):1151-1164. doi: 10.1002/jimd.12388. Epub 2021 May 04.

In this study, we characterize the natural course of metachromatic leukodystrophy (MLD), explore intra/inter group differences, and identify biomarkers to monitor disease progression. This is a longitudinal observational study. Genotype and characteristics at disease onset were recorded. Time-to-event analyses...

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Fumagalli F, Zambon AA, Rancoita PMV, et al. Metachromatic leukodystrophy: A single-center longitudinal study of 45 patients. J Inherit Metab Dis. 2021;44(5):1151-1164doi: 10.1002/jimd.12388.
Fumagalli, F., Zambon, A. A., Rancoita, P. M. V., Baldoli, C., Canale, S., Spiga, I., Medaglini, S., Penati, R., Facchini, M., Ciotti, F., Sarzana, M., Lorioli, L., Cesani, M., Natali Sora, M. G., Del Carro, U., Cugnata, F., Antonioli, G., Recupero, S., Calbi, V., Di Serio, C., Aiuti, A., Biffi, A., & Sessa, M. (2021). Metachromatic leukodystrophy: A single-center longitudinal study of 45 patients. Journal of inherited metabolic disease, 44(5), 1151-1164. https://doi.org/10.1002/jimd.12388
Fumagalli, Francesca, et al. "Metachromatic leukodystrophy: A single-center longitudinal study of 45 patients." Journal of inherited metabolic disease vol. 44,5 (2021): 1151-1164. doi: https://doi.org/10.1002/jimd.12388
Fumagalli F, Zambon AA, Rancoita PMV, Baldoli C, Canale S, Spiga I, Medaglini S, Penati R, Facchini M, Ciotti F, Sarzana M, Lorioli L, Cesani M, Natali Sora MG, Del Carro U, Cugnata F, Antonioli G, Recupero S, Calbi V, Di Serio C, Aiuti A, Biffi A, Sessa M. Metachromatic leukodystrophy: A single-center longitudinal study of 45 patients. J Inherit Metab Dis. 2021 Sep;44(5):1151-1164. doi: 10.1002/jimd.12388. Epub 2021 May 04. PMID: 33855715.
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Antibacterial Activity of Linezolid against Gram-Negative Bacteria: Utilization of ε-Poly-l-Lysine Capped Silica Xerogel as an Activating Carrier.

Pharmaceutics

Guzel Kaya G, Medaglia S, Candela-Noguera V, Tormo-Mas MÁ, Marcos MD, Aznar E, Deveci H, Martínez-Máñez R.
PMID: 33233423
Pharmaceutics. 2020 Nov 21;12(11). doi: 10.3390/pharmaceutics12111126.

In recent times, many approaches have been developed against drug resistant Gram-negative bacteria. However, low-cost high effective materials which could broaden the spectrum of antibiotics are still needed. In this study, enhancement of linezolid spectrum, normally active against Gram-positive...

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Guzel Kaya G, Medaglia S, Candela-Noguera V, et al. Antibacterial Activity of Linezolid against Gram-Negative Bacteria: Utilization of ε-Poly-l-Lysine Capped Silica Xerogel as an Activating Carrier. Pharmaceutics. 2020;12(11)doi: 10.3390/pharmaceutics12111126.
Guzel Kaya, G., Medaglia, S., Candela-Noguera, V., Tormo-Mas, M. �. �., Marcos, M. D., Aznar, E., Deveci, H., & Martínez-Máñez, R. (2020). Antibacterial Activity of Linezolid against Gram-Negative Bacteria: Utilization of ε-Poly-l-Lysine Capped Silica Xerogel as an Activating Carrier. Pharmaceutics, 12(11), . https://doi.org/10.3390/pharmaceutics12111126
Guzel Kaya, Gulcihan, et al. "Antibacterial Activity of Linezolid against Gram-Negative Bacteria: Utilization of ε-Poly-l-Lysine Capped Silica Xerogel as an Activating Carrier." Pharmaceutics vol. 12,11 (2020). doi: https://doi.org/10.3390/pharmaceutics12111126
Guzel Kaya G, Medaglia S, Candela-Noguera V, Tormo-Mas MÁ, Marcos MD, Aznar E, Deveci H, Martínez-Máñez R. Antibacterial Activity of Linezolid against Gram-Negative Bacteria: Utilization of ε-Poly-l-Lysine Capped Silica Xerogel as an Activating Carrier. Pharmaceutics. 2020 Nov 21;12(11). doi: 10.3390/pharmaceutics12111126. PMID: 33233423; PMCID: PMC7700326.
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Short or Long Interval between Priming and Boosting: Does It Impact on the Vaccine Immunogenicity?.

Vaccines

Pettini E, Pastore G, Fiorino F, Medaglini D, Ciabattini A.
PMID: 33804604
Vaccines (Basel). 2021 Mar 20;9(3). doi: 10.3390/vaccines9030289.

Characterizing the impact of the vaccination schedule on the induction of B and T cell immune responses is critical for improving vaccine immunogenicity. Here we compare the effect of a short (4 weeks) or a long (18 weeks) interval...

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Pettini E, Pastore G, Fiorino F, et al. Short or Long Interval between Priming and Boosting: Does It Impact on the Vaccine Immunogenicity?. Vaccines (Basel). 2021;9(3)doi: 10.3390/vaccines9030289.
Pettini, E., Pastore, G., Fiorino, F., Medaglini, D., & Ciabattini, A. (2021). Short or Long Interval between Priming and Boosting: Does It Impact on the Vaccine Immunogenicity?. Vaccines, 9(3), . https://doi.org/10.3390/vaccines9030289
Pettini, Elena, et al. "Short or Long Interval between Priming and Boosting: Does It Impact on the Vaccine Immunogenicity?." Vaccines vol. 9,3 (2021). doi: https://doi.org/10.3390/vaccines9030289
Pettini E, Pastore G, Fiorino F, Medaglini D, Ciabattini A. Short or Long Interval between Priming and Boosting: Does It Impact on the Vaccine Immunogenicity?. Vaccines (Basel). 2021 Mar 20;9(3). doi: 10.3390/vaccines9030289. PMID: 33804604; PMCID: PMC8003773.
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From Bivariate to Multivariate Analysis of Cytometric Data: Overview of Computational Methods and Their Application in Vaccination Studies.

Vaccines

Lucchesi S, Furini S, Medaglini D, Ciabattini A.
PMID: 32244919
Vaccines (Basel). 2020 Mar 20;8(1). doi: 10.3390/vaccines8010138.

Flow and mass cytometry are used to quantify the expression of multiple extracellular or intracellular molecules on single cells, allowing the phenotypic and functional characterization of complex cell populations. Multiparametric flow cytometry is particularly suitable for deep analysis of...

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Lucchesi S, Furini S, Medaglini D, et al. From Bivariate to Multivariate Analysis of Cytometric Data: Overview of Computational Methods and Their Application in Vaccination Studies. Vaccines (Basel). 2020;8(1)doi: 10.3390/vaccines8010138.
Lucchesi, S., Furini, S., Medaglini, D., & Ciabattini, A. (2020). From Bivariate to Multivariate Analysis of Cytometric Data: Overview of Computational Methods and Their Application in Vaccination Studies. Vaccines, 8(1), . https://doi.org/10.3390/vaccines8010138
Lucchesi, Simone, et al. "From Bivariate to Multivariate Analysis of Cytometric Data: Overview of Computational Methods and Their Application in Vaccination Studies." Vaccines vol. 8,1 (2020). doi: https://doi.org/10.3390/vaccines8010138
Lucchesi S, Furini S, Medaglini D, Ciabattini A. From Bivariate to Multivariate Analysis of Cytometric Data: Overview of Computational Methods and Their Application in Vaccination Studies. Vaccines (Basel). 2020 Mar 20;8(1). doi: 10.3390/vaccines8010138. PMID: 32244919; PMCID: PMC7157606.
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Role of the Microbiota in the Modulation of Vaccine Immune Responses.

Frontiers in microbiology

Ciabattini A, Olivieri R, Lazzeri E, Medaglini D.
PMID: 31333592
Front Microbiol. 2019 Jul 03;10:1305. doi: 10.3389/fmicb.2019.01305. eCollection 2019.

The human immune system and the microbiota co-evolve, and their balanced relationship is based on crosstalk between the two systems through the course of life. This tight association and the overall composition and richness of the microbiota play an...

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Ciabattini A, Olivieri R, Lazzeri E, et al. Role of the Microbiota in the Modulation of Vaccine Immune Responses. Front Microbiol. 2019;10:1305doi: 10.3389/fmicb.2019.01305.
Ciabattini, A., Olivieri, R., Lazzeri, E., & Medaglini, D. (2019). Role of the Microbiota in the Modulation of Vaccine Immune Responses. Frontiers in microbiology, 101305. https://doi.org/10.3389/fmicb.2019.01305
Ciabattini, Annalisa, et al. "Role of the Microbiota in the Modulation of Vaccine Immune Responses." Frontiers in microbiology vol. 10 (2019): 1305. doi: https://doi.org/10.3389/fmicb.2019.01305
Ciabattini A, Olivieri R, Lazzeri E, Medaglini D. Role of the Microbiota in the Modulation of Vaccine Immune Responses. Front Microbiol. 2019 Jul 03;10:1305. doi: 10.3389/fmicb.2019.01305. eCollection 2019. PMID: 31333592; PMCID: PMC6616116.
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Prime-boost strategies in mucosal immunization affect local IgA production and the type of th response.

Frontiers in immunology

Fiorino F, Pettini E, Pozzi G, Medaglini D, Ciabattini A.
PMID: 23755051
Front Immunol. 2013 May 29;4:128. doi: 10.3389/fimmu.2013.00128. eCollection 2013.

Combinations of different delivery routes for priming and boosting represent vaccination strategies that can modulate magnitude, quality, and localization of the immune response. A murine model was used to study T cell clonal expansion following intranasal (IN) or subcutaneous...

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Fiorino F, Pettini E, Pozzi G, et al. Prime-boost strategies in mucosal immunization affect local IgA production and the type of th response. Front Immunol. 2013;4:128doi: 10.3389/fimmu.2013.00128.
Fiorino, F., Pettini, E., Pozzi, G., Medaglini, D., & Ciabattini, A. (2013). Prime-boost strategies in mucosal immunization affect local IgA production and the type of th response. Frontiers in immunology, 4128. https://doi.org/10.3389/fimmu.2013.00128
Fiorino, Fabio, et al. "Prime-boost strategies in mucosal immunization affect local IgA production and the type of th response." Frontiers in immunology vol. 4 (2013): 128. doi: https://doi.org/10.3389/fimmu.2013.00128
Fiorino F, Pettini E, Pozzi G, Medaglini D, Ciabattini A. Prime-boost strategies in mucosal immunization affect local IgA production and the type of th response. Front Immunol. 2013 May 29;4:128. doi: 10.3389/fimmu.2013.00128. eCollection 2013. PMID: 23755051; PMCID: PMC3665932.
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Rapid dose-dependent Natural Killer (NK) cell modulation and cytokine responses following human rVSV-ZEBOV Ebolavirus vaccination.

NPJ vaccines

Pejoski D, de Rham C, Martinez-Murillo P, Santoro F, Auderset F, Medaglini D, Pozzi G, Vono M, Lambert PH, Huttner A, Haks MC, Ottenhoff THM, Villard J, Siegrist CA.
PMID: 32337075
NPJ Vaccines. 2020 Apr 14;5(1):32. doi: 10.1038/s41541-020-0179-4. eCollection 2020.

The rVSV-ZEBOV Ebolavirus vaccine confers protection within days after immunization, suggesting the contribution of innate immune responses. We report modulation of rVSV-ZEBOV vaccinee blood CD56

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Pejoski D, de Rham C, Martinez-Murillo P, et al. Rapid dose-dependent Natural Killer (NK) cell modulation and cytokine responses following human rVSV-ZEBOV Ebolavirus vaccination. NPJ Vaccines. 2020;5(1):32doi: 10.1038/s41541-020-0179-4.
Pejoski, D., de Rham, C., Martinez-Murillo, P., Santoro, F., Auderset, F., Medaglini, D., Pozzi, G., Vono, M., Lambert, P. H., Huttner, A., Haks, M. C., Ottenhoff, T. H. M., Villard, J., Siegrist, C. A. (2020). Rapid dose-dependent Natural Killer (NK) cell modulation and cytokine responses following human rVSV-ZEBOV Ebolavirus vaccination. NPJ vaccines, 5(1), 32. https://doi.org/10.1038/s41541-020-0179-4
Pejoski, David, et al. "Rapid dose-dependent Natural Killer (NK) cell modulation and cytokine responses following human rVSV-ZEBOV Ebolavirus vaccination." NPJ vaccines vol. 5,1 (2020): 32. doi: https://doi.org/10.1038/s41541-020-0179-4
Pejoski D, de Rham C, Martinez-Murillo P, Santoro F, Auderset F, Medaglini D, Pozzi G, Vono M, Lambert PH, Huttner A, Haks MC, Ottenhoff THM, Villard J, Siegrist CA. Rapid dose-dependent Natural Killer (NK) cell modulation and cytokine responses following human rVSV-ZEBOV Ebolavirus vaccination. NPJ Vaccines. 2020 Apr 14;5(1):32. doi: 10.1038/s41541-020-0179-4. eCollection 2020. PMID: 32337075; PMCID: PMC7156503.
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Modulation of Primary Immune Response by Different Vaccine Adjuvants.

Frontiers in immunology

Ciabattini A, Pettini E, Fiorino F, Pastore G, Andersen P, Pozzi G, Medaglini D.
PMID: 27781036
Front Immunol. 2016 Oct 17;7:427. doi: 10.3389/fimmu.2016.00427. eCollection 2016.

Adjuvants contribute to enhancing and shaping the vaccine immune response through different modes of action. Here early biomarkers of adjuvanticity after primary immunization were investigated using four different adjuvants combined with the chimeric tuberculosis vaccine antigen H56. C57BL/6 mice...

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Ciabattini A, Pettini E, Fiorino F, et al. Modulation of Primary Immune Response by Different Vaccine Adjuvants. Front Immunol. 2016;7:427doi: 10.3389/fimmu.2016.00427.
Ciabattini, A., Pettini, E., Fiorino, F., Pastore, G., Andersen, P., Pozzi, G., & Medaglini, D. (2016). Modulation of Primary Immune Response by Different Vaccine Adjuvants. Frontiers in immunology, 7427. https://doi.org/10.3389/fimmu.2016.00427
Ciabattini, Annalisa, et al. "Modulation of Primary Immune Response by Different Vaccine Adjuvants." Frontiers in immunology vol. 7 (2016): 427. doi: https://doi.org/10.3389/fimmu.2016.00427
Ciabattini A, Pettini E, Fiorino F, Pastore G, Andersen P, Pozzi G, Medaglini D. Modulation of Primary Immune Response by Different Vaccine Adjuvants. Front Immunol. 2016 Oct 17;7:427. doi: 10.3389/fimmu.2016.00427. eCollection 2016. PMID: 27781036; PMCID: PMC5066114.
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Showing 1 to 12 of 23 entries