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Spatial Separation of Plk1 Phosphorylation and Activity.

Frontiers in oncology

Bruinsma W, Aprelia M, Kool J, Macurek L, Lindqvist A, Medema RH.
PMID: 26114094
Front Oncol. 2015 Jun 10;5:132. doi: 10.3389/fonc.2015.00132. eCollection 2015.

Polo-like kinase 1 (Plk1) is one of the major kinases controlling mitosis and cell division. Plk1 is first recruited to the centrosome in S phase, then appears on the kinetochores in late G2, and at the end of mitosis,...

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Bruinsma W, Aprelia M, Kool J, et al. Spatial Separation of Plk1 Phosphorylation and Activity. Front Oncol. 2015;5:132doi: 10.3389/fonc.2015.00132.
Bruinsma, W., Aprelia, M., Kool, J., Macurek, L., Lindqvist, A., & Medema, R. H. (2015). Spatial Separation of Plk1 Phosphorylation and Activity. Frontiers in oncology, 5132. https://doi.org/10.3389/fonc.2015.00132
Bruinsma, Wytse, et al. "Spatial Separation of Plk1 Phosphorylation and Activity." Frontiers in oncology vol. 5 (2015): 132. doi: https://doi.org/10.3389/fonc.2015.00132
Bruinsma W, Aprelia M, Kool J, Macurek L, Lindqvist A, Medema RH. Spatial Separation of Plk1 Phosphorylation and Activity. Front Oncol. 2015 Jun 10;5:132. doi: 10.3389/fonc.2015.00132. eCollection 2015. PMID: 26114094; PMCID: PMC4462105.
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Methylation of WNT target genes AXIN2 and DKK1 as robust biomarkers for recurrence prediction in stage II colon cancer.

Oncogenesis

Kandimalla R, Linnekamp JF, van Hooff S, Castells A, Llor X, Andreu M, Jover R, Goel A, Medema JP.
PMID: 28368388
Oncogenesis. 2017 Apr 03;6(4):e308. doi: 10.1038/oncsis.2017.9.

Stage II colon cancer (CC) still remains a clinical challenge with patient stratification for adjuvant therapy (AT) largely relying on clinical parameters. Prognostic biomarkers are urgently needed for better stratification. Previously, we have shown that WNT target genes AXIN2,...

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Kandimalla R, Linnekamp JF, van Hooff S, et al. Methylation of WNT target genes AXIN2 and DKK1 as robust biomarkers for recurrence prediction in stage II colon cancer. Oncogenesis. 2017;6(4):e308doi: 10.1038/oncsis.2017.9.
Kandimalla, R., Linnekamp, J. F., van Hooff, S., Castells, A., Llor, X., Andreu, M., Jover, R., Goel, A., & Medema, J. P. (2017). Methylation of WNT target genes AXIN2 and DKK1 as robust biomarkers for recurrence prediction in stage II colon cancer. Oncogenesis, 6(4), e308. https://doi.org/10.1038/oncsis.2017.9
Kandimalla, R, et al. "Methylation of WNT target genes AXIN2 and DKK1 as robust biomarkers for recurrence prediction in stage II colon cancer." Oncogenesis vol. 6,4 (2017): e308. doi: https://doi.org/10.1038/oncsis.2017.9
Kandimalla R, Linnekamp JF, van Hooff S, Castells A, Llor X, Andreu M, Jover R, Goel A, Medema JP. Methylation of WNT target genes AXIN2 and DKK1 as robust biomarkers for recurrence prediction in stage II colon cancer. Oncogenesis. 2017 Apr 03;6(4):e308. doi: 10.1038/oncsis.2017.9. PMID: 28368388; PMCID: PMC5520503.
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Carcinoma of the oesophagus: correlation of radiological appearance with response to radiotherapy.

The Indian journal of chest diseases & allied sciences

Vyas RK, Baboo HA, Neema JP, Singhal S, Dixit S, Murthy R.
PMID: 8125534
Indian J Chest Dis Allied Sci. 1993 Jul-Sep;35(3):113-6.

In order to predict possibility of local control in carcinoma of the oesophagus by radiotherapy, the relationship between the x-ray findings before and after radiotherapy were analyzed in 55 irradiated cases. In the superficial or proliferative type on x-ray...

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Vyas RK, Baboo HA, Neema JP, et al. Carcinoma of the oesophagus: correlation of radiological appearance with response to radiotherapy. Indian J Chest Dis Allied Sci. 1993;35(3):113-6
Vyas, R. K., Baboo, H. A., Neema, J. P., Singhal, S., Dixit, S., & Murthy, R. (1993). Carcinoma of the oesophagus: correlation of radiological appearance with response to radiotherapy. The Indian journal of chest diseases & allied sciences, 35(3), 113-6.
Vyas, R K, et al. "Carcinoma of the oesophagus: correlation of radiological appearance with response to radiotherapy." The Indian journal of chest diseases & allied sciences vol. 35,3 (1993): 113-6.
Vyas RK, Baboo HA, Neema JP, Singhal S, Dixit S, Murthy R. Carcinoma of the oesophagus: correlation of radiological appearance with response to radiotherapy. Indian J Chest Dis Allied Sci. 1993 Jul-Sep;35(3):113-6. PMID: 8125534.
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Does the Caenorhabditis elegans protein CED-4 contain a region of homology to the mammalian death effector domain?.

Cell death and differentiation

Peter ME, Medema JP, Krammer PH.
PMID: 14555964
Cell Death Differ. 1997 Oct;4(7):523-5. doi: 10.1038/sj.cdd.4400285.

No abstract available.

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Peter ME, Medema JP, Krammer PH. Does the Caenorhabditis elegans protein CED-4 contain a region of homology to the mammalian death effector domain?. Cell Death Differ. 1997;4(7):523-5doi: 10.1038/sj.cdd.4400285.
Peter, M. E., Medema, J. P., & Krammer, P. H. (1997). Does the Caenorhabditis elegans protein CED-4 contain a region of homology to the mammalian death effector domain?. Cell death and differentiation, 4(7), 523-5. https://doi.org/10.1038/sj.cdd.4400285
Peter, M E, et al. "Does the Caenorhabditis elegans protein CED-4 contain a region of homology to the mammalian death effector domain?." Cell death and differentiation vol. 4,7 (1997): 523-5. doi: https://doi.org/10.1038/sj.cdd.4400285
Peter ME, Medema JP, Krammer PH. Does the Caenorhabditis elegans protein CED-4 contain a region of homology to the mammalian death effector domain?. Cell Death Differ. 1997 Oct;4(7):523-5. doi: 10.1038/sj.cdd.4400285. PMID: 14555964.
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Pit cells exclusively kill P815 tumor cells by the perforin/granzyme pathway.

Comparative hepatology

Vermijlen D, Luo D, Froelich CJ, Medema JP, Kummer JA, Willems E, Braet F, Wisse E.
PMID: 14960210
Comp Hepatol. 2004 Jan 14;3:S58. doi: 10.1186/1476-5926-2-S1-S58.

No abstract available.

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Vermijlen D, Luo D, Froelich CJ, et al. Pit cells exclusively kill P815 tumor cells by the perforin/granzyme pathway. Comp Hepatol. 2004;3:S58doi: 10.1186/1476-5926-2-S1-S58.
Vermijlen, D., Luo, D., Froelich, C. J., Medema, J. P., Kummer, J. A., Willems, E., Braet, F., & Wisse, E. (2004). Pit cells exclusively kill P815 tumor cells by the perforin/granzyme pathway. Comparative hepatology, 3S58. https://doi.org/10.1186/1476-5926-2-S1-S58
Vermijlen, David, et al. "Pit cells exclusively kill P815 tumor cells by the perforin/granzyme pathway." Comparative hepatology vol. 3 (2004): S58. doi: https://doi.org/10.1186/1476-5926-2-S1-S58
Vermijlen D, Luo D, Froelich CJ, Medema JP, Kummer JA, Willems E, Braet F, Wisse E. Pit cells exclusively kill P815 tumor cells by the perforin/granzyme pathway. Comp Hepatol. 2004 Jan 14;3:S58. doi: 10.1186/1476-5926-2-S1-S58. PMID: 14960210; PMCID: PMC2410270.
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ADAM12 is a circulating marker for stromal activation in pancreatic cancer and predicts response to chemotherapy.

Oncogenesis

Veenstra VL, Damhofer H, Waasdorp C, van Rijssen LB, van de Vijver MJ, Dijk F, Wilmink HW, Besselink MG, Busch OR, Chang DK, Bailey PJ, Biankin AV, Kocher HM, Medema JP, Li JS, Jiang R, Pierce DW, van Laarhoven HWM, Bijlsma MF.
PMID: 30442938
Oncogenesis. 2018 Nov 16;7(11):87. doi: 10.1038/s41389-018-0096-9.

Pancreatic ductal adenocarcinoma (PDAC) is characterized by abundant stroma that harbors tumor-promoting properties. No good biomarkers exist to monitor the effect of stromal targeting therapies or to predict response. We set out to identify such non-invasive markers for PDAC...

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Veenstra VL, Damhofer H, Waasdorp C, et al. ADAM12 is a circulating marker for stromal activation in pancreatic cancer and predicts response to chemotherapy. Oncogenesis. 2018;7(11):87doi: 10.1038/s41389-018-0096-9.
Veenstra, V. L., Damhofer, H., Waasdorp, C., van Rijssen, L. B., van de Vijver, M. J., Dijk, F., Wilmink, H. W., Besselink, M. G., Busch, O. R., Chang, D. K., Bailey, P. J., Biankin, A. V., Kocher, H. M., Medema, J. P., Li, J. S., Jiang, R., Pierce, D. W., van Laarhoven, H. W. M., & Bijlsma, M. F. (2018). ADAM12 is a circulating marker for stromal activation in pancreatic cancer and predicts response to chemotherapy. Oncogenesis, 7(11), 87. https://doi.org/10.1038/s41389-018-0096-9
Veenstra, V L, et al. "ADAM12 is a circulating marker for stromal activation in pancreatic cancer and predicts response to chemotherapy." Oncogenesis vol. 7,11 (2018): 87. doi: https://doi.org/10.1038/s41389-018-0096-9
Veenstra VL, Damhofer H, Waasdorp C, van Rijssen LB, van de Vijver MJ, Dijk F, Wilmink HW, Besselink MG, Busch OR, Chang DK, Bailey PJ, Biankin AV, Kocher HM, Medema JP, Li JS, Jiang R, Pierce DW, van Laarhoven HWM, Bijlsma MF. ADAM12 is a circulating marker for stromal activation in pancreatic cancer and predicts response to chemotherapy. Oncogenesis. 2018 Nov 16;7(11):87. doi: 10.1038/s41389-018-0096-9. PMID: 30442938; PMCID: PMC6237826.
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CFTR is a tumor suppressor gene in murine and human intestinal cancer.

Oncogene

Than BLN, Linnekamp JF, Starr TK, Largaespada DA, Rod A, Zhang Y, Bruner V, Abrahante J, Schumann A, Luczak T, Walter J, Niemczyk A, O'Sullivan MG, Medema JP, Fijneman RJA, Meijer GA, Van den Broek E, Hodges CA, Scott PM, Vermeulen L, Cormier RT.
PMID: 28192405
Oncogene. 2017 Jun 15;36(24):3504. doi: 10.1038/onc.2017.3. Epub 2017 Feb 13.

This corrects the article DOI: 10.1038/onc.2015.483.

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Than BLN, Linnekamp JF, Starr TK, et al. CFTR is a tumor suppressor gene in murine and human intestinal cancer. Oncogene. 2017;36(24):3504doi: 10.1038/onc.2017.3.
Than, B. L. N., Linnekamp, J. F., Starr, T. K., Largaespada, D. A., Rod, A., Zhang, Y., Bruner, V., Abrahante, J., Schumann, A., Luczak, T., Walter, J., Niemczyk, A., O'Sullivan, M. G., Medema, J. P., Fijneman, R. J. A., Meijer, G. A., Van den Broek, E., Hodges, C. A., Scott, P. M., Vermeulen, L., & Cormier, R. T. (2017). CFTR is a tumor suppressor gene in murine and human intestinal cancer. Oncogene, 36(24), 3504. https://doi.org/10.1038/onc.2017.3
Than, B L N, et al. "CFTR is a tumor suppressor gene in murine and human intestinal cancer." Oncogene vol. 36,24 (2017): 3504. doi: https://doi.org/10.1038/onc.2017.3
Than BLN, Linnekamp JF, Starr TK, Largaespada DA, Rod A, Zhang Y, Bruner V, Abrahante J, Schumann A, Luczak T, Walter J, Niemczyk A, O'Sullivan MG, Medema JP, Fijneman RJA, Meijer GA, Van den Broek E, Hodges CA, Scott PM, Vermeulen L, Cormier RT. CFTR is a tumor suppressor gene in murine and human intestinal cancer. Oncogene. 2017 Jun 15;36(24):3504. doi: 10.1038/onc.2017.3. Epub 2017 Feb 13. PMID: 28192405.
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Impact of G-CSF administration post-allogeneic hematopoietic stem-cell transplantation on outcomes: a systematic review and meta-analysis.

American journal of blood research

Gupta AK, Meena JP, Haldar P, Tanwar P, Seth R.
PMID: 34824887
Am J Blood Res. 2021 Oct 15;11(5):544-563. eCollection 2021.

Granulocyte colony-stimulating factors (G-CSFs) have been used post hematopoietic stem cell transplant (HSCT) for earlier neutrophil engraftment. The use of G-CSFs, and their effect on other post-HSCT outcomes remains debatable. In this systematic review and meta-analysis, we searched PubMed,...

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Gupta AK, Meena JP, Haldar P, et al. Impact of G-CSF administration post-allogeneic hematopoietic stem-cell transplantation on outcomes: a systematic review and meta-analysis. Am J Blood Res. 2021;11(5):544-563
Gupta, A. K., Meena, J. P., Haldar, P., Tanwar, P., & Seth, R. (2021). Impact of G-CSF administration post-allogeneic hematopoietic stem-cell transplantation on outcomes: a systematic review and meta-analysis. American journal of blood research, 11(5), 544-563.
Gupta, Aditya Kumar, et al. "Impact of G-CSF administration post-allogeneic hematopoietic stem-cell transplantation on outcomes: a systematic review and meta-analysis." American journal of blood research vol. 11,5 (2021): 544-563.
Gupta AK, Meena JP, Haldar P, Tanwar P, Seth R. Impact of G-CSF administration post-allogeneic hematopoietic stem-cell transplantation on outcomes: a systematic review and meta-analysis. Am J Blood Res. 2021 Oct 15;11(5):544-563. eCollection 2021. PMID: 34824887; PMCID: PMC8610798.
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Early Cost-effectiveness Analysis of Risk-Based Selection Strategies for Adjuvant Treatment in Stage II Colon Cancer: The Potential Value of Prognostic Molecular Markers.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Jongeneel G, Greuter MJE, Kunst N, van Erning FN, Koopman M, Medema JP, Vermeulen L, Ijzermans JNM, Vink GR, Punt CJA, Coupé VMH.
PMID: 34162659
Cancer Epidemiol Biomarkers Prev. 2021 Sep;30(9):1726-1734. doi: 10.1158/1055-9965.EPI-21-0078. Epub 2021 Jun 23.

BACKGROUND: To explore the potential value of consensus molecular subtypes (CMS) in stage II colon cancer treatment selection, we carried out an early cost-effectiveness assessment of a CMS-based strategy for adjuvant chemotherapy.METHODS: We used a Markov cohort model to...

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Jongeneel G, Greuter MJE, Kunst N, et al. Early Cost-effectiveness Analysis of Risk-Based Selection Strategies for Adjuvant Treatment in Stage II Colon Cancer: The Potential Value of Prognostic Molecular Markers. Cancer Epidemiol Biomarkers Prev. 2021;30(9):1726-1734doi: 10.1158/1055-9965.EPI-21-0078.
Jongeneel, G., Greuter, M. J. E., Kunst, N., van Erning, F. N., Koopman, M., Medema, J. P., Vermeulen, L., Ijzermans, J. N. M., Vink, G. R., Punt, C. J. A., & Coupé, V. M. H. (2021). Early Cost-effectiveness Analysis of Risk-Based Selection Strategies for Adjuvant Treatment in Stage II Colon Cancer: The Potential Value of Prognostic Molecular Markers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 30(9), 1726-1734. https://doi.org/10.1158/1055-9965.EPI-21-0078
Jongeneel, Gabrielle, et al. "Early Cost-effectiveness Analysis of Risk-Based Selection Strategies for Adjuvant Treatment in Stage II Colon Cancer: The Potential Value of Prognostic Molecular Markers." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology vol. 30,9 (2021): 1726-1734. doi: https://doi.org/10.1158/1055-9965.EPI-21-0078
Jongeneel G, Greuter MJE, Kunst N, van Erning FN, Koopman M, Medema JP, Vermeulen L, Ijzermans JNM, Vink GR, Punt CJA, Coupé VMH. Early Cost-effectiveness Analysis of Risk-Based Selection Strategies for Adjuvant Treatment in Stage II Colon Cancer: The Potential Value of Prognostic Molecular Markers. Cancer Epidemiol Biomarkers Prev. 2021 Sep;30(9):1726-1734. doi: 10.1158/1055-9965.EPI-21-0078. Epub 2021 Jun 23. PMID: 34162659; PMCID: PMC7611620.
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Corrigendum to "Quantitative risk assessment of norovirus and adenovirus for the use of reclaimed water to irrigate lettuce in Catalonia" Water Research 153 (2019) 91-99.

Water research

Gonzales-Gustavson E, Rusiñol M, Medema G, Calvo M, Girones R.
PMID: 34974346
Water Res. 2021 Dec 30;210:117978. doi: 10.1016/j.watres.2021.117978. Epub 2021 Dec 30.

No abstract available.

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Gonzales-Gustavson E, Rusiñol M, Medema G, et al. Corrigendum to "Quantitative risk assessment of norovirus and adenovirus for the use of reclaimed water to irrigate lettuce in Catalonia" Water Research 153 (2019) 91-99. Water Res. 2021;210:117978doi: 10.1016/j.watres.2021.117978.
Gonzales-Gustavson, E., Rusiñol, M., Medema, G., Calvo, M., & Girones, R. (2021). Corrigendum to "Quantitative risk assessment of norovirus and adenovirus for the use of reclaimed water to irrigate lettuce in Catalonia" Water Research 153 (2019) 91-99. Water research, 210117978. https://doi.org/10.1016/j.watres.2021.117978
Gonzales-Gustavson, Eloy, et al. "Corrigendum to "Quantitative risk assessment of norovirus and adenovirus for the use of reclaimed water to irrigate lettuce in Catalonia" Water Research 153 (2019) 91-99." Water research vol. 210 (2021): 117978. doi: https://doi.org/10.1016/j.watres.2021.117978
Gonzales-Gustavson E, Rusiñol M, Medema G, Calvo M, Girones R. Corrigendum to "Quantitative risk assessment of norovirus and adenovirus for the use of reclaimed water to irrigate lettuce in Catalonia" Water Research 153 (2019) 91-99. Water Res. 2021 Dec 30;210:117978. doi: 10.1016/j.watres.2021.117978. Epub 2021 Dec 30. PMID: 34974346.
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Corrigendum to "Quantitative risk assessment of norovirus and adenovirus for the use of reclaimed water to irrigate lettuce in Catalonia" Water Research 153 (2019) 91-99.

Water research

Gonzales-Gustavson E, Rusiñol M, Medema G, Calvo M, Girones R.
PMID: 34974346
Water Res. 2021 Dec 30;210:117978. doi: 10.1016/j.watres.2021.117978. Epub 2021 Dec 30.

No abstract available.

Cite
Gonzales-Gustavson E, Rusiñol M, Medema G, et al. Corrigendum to "Quantitative risk assessment of norovirus and adenovirus for the use of reclaimed water to irrigate lettuce in Catalonia" Water Research 153 (2019) 91-99. Water Res. 2021;210:117978doi: 10.1016/j.watres.2021.117978.
Gonzales-Gustavson, E., Rusiñol, M., Medema, G., Calvo, M., & Girones, R. (2021). Corrigendum to "Quantitative risk assessment of norovirus and adenovirus for the use of reclaimed water to irrigate lettuce in Catalonia" Water Research 153 (2019) 91-99. Water research, 210117978. https://doi.org/10.1016/j.watres.2021.117978
Gonzales-Gustavson, Eloy, et al. "Corrigendum to "Quantitative risk assessment of norovirus and adenovirus for the use of reclaimed water to irrigate lettuce in Catalonia" Water Research 153 (2019) 91-99." Water research vol. 210 (2021): 117978. doi: https://doi.org/10.1016/j.watres.2021.117978
Gonzales-Gustavson E, Rusiñol M, Medema G, Calvo M, Girones R. Corrigendum to "Quantitative risk assessment of norovirus and adenovirus for the use of reclaimed water to irrigate lettuce in Catalonia" Water Research 153 (2019) 91-99. Water Res. 2021 Dec 30;210:117978. doi: 10.1016/j.watres.2021.117978. Epub 2021 Dec 30. PMID: 34974346.
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Molecular update on biology of Wilms Tumor 1 gene and its applications in acute myeloid leukemia.

American journal of blood research

Goel H, Rahul E, Gupta AK, Meena JP, Chopra A, Ranjan A, Hussain S, Rath GK, Tanwar P.
PMID: 33224559
Am J Blood Res. 2020 Oct 15;10(5):151-160. eCollection 2020.

Wilms tumor gene 1 (WT1) is an important gene which is involved in growth and development of many organs. It is identified as a tumor suppressor gene in nephroblastoma. However, its role as a tumor oncogene has been highlighted...

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Goel H, Rahul E, Gupta AK, et al. Molecular update on biology of Wilms Tumor 1 gene and its applications in acute myeloid leukemia. Am J Blood Res. 2020;10(5):151-160
Goel, H., Rahul, E., Gupta, A. K., Meena, J. P., Chopra, A., Ranjan, A., Hussain, S., Rath, G. K., & Tanwar, P. (2020). Molecular update on biology of Wilms Tumor 1 gene and its applications in acute myeloid leukemia. American journal of blood research, 10(5), 151-160.
Goel, Harsh, et al. "Molecular update on biology of Wilms Tumor 1 gene and its applications in acute myeloid leukemia." American journal of blood research vol. 10,5 (2020): 151-160.
Goel H, Rahul E, Gupta AK, Meena JP, Chopra A, Ranjan A, Hussain S, Rath GK, Tanwar P. Molecular update on biology of Wilms Tumor 1 gene and its applications in acute myeloid leukemia. Am J Blood Res. 2020 Oct 15;10(5):151-160. eCollection 2020. PMID: 33224559; PMCID: PMC7675129.
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