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Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors.

ACS medicinal chemistry letters

Cadoni R, Pala N, Lomelino C, Mahon BP, McKenna R, Dallocchio R, Dessì A, Carcelli M, Rogolino D, Sanna V, Rassu M, Iaccarino C, Vullo D, Supuran CT, Sechi M.
PMID: 28947941
ACS Med Chem Lett. 2017 Jul 31;8(9):941-946. doi: 10.1021/acsmedchemlett.7b00229. eCollection 2017 Sep 14.

We report the synthesis, biological evaluation, and structural study of a series of substituted heteroaryl-pyrazole carboxylic acid derivatives. These compounds have been developed as inhibitors of specific isoforms of carbonic anhydrase (CA), with potential as prototypes of a new...

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Cadoni R, Pala N, Lomelino C, et al. Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors. ACS Med Chem Lett. 2017;8(9):941-946doi: 10.1021/acsmedchemlett.7b00229.
Cadoni, R., Pala, N., Lomelino, C., Mahon, B. P., McKenna, R., Dallocchio, R., Dessì, A., Carcelli, M., Rogolino, D., Sanna, V., Rassu, M., Iaccarino, C., Vullo, D., Supuran, C. T., & Sechi, M. (2017). Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors. ACS medicinal chemistry letters, 8(9), 941-946. https://doi.org/10.1021/acsmedchemlett.7b00229
Cadoni, Roberta, et al. "Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors." ACS medicinal chemistry letters vol. 8,9 (2017): 941-946. doi: https://doi.org/10.1021/acsmedchemlett.7b00229
Cadoni R, Pala N, Lomelino C, Mahon BP, McKenna R, Dallocchio R, Dessì A, Carcelli M, Rogolino D, Sanna V, Rassu M, Iaccarino C, Vullo D, Supuran CT, Sechi M. Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors. ACS Med Chem Lett. 2017 Jul 31;8(9):941-946. doi: 10.1021/acsmedchemlett.7b00229. eCollection 2017 Sep 14. PMID: 28947941; PMCID: PMC5601383.
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GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation.

Cell cycle (Georgetown, Tex.)

Velletri T, Romeo F, Tucci P, Peschiaroli A, Annicchiarico-Petruzzelli M, Niklison-Chirou M, Amelio I, Knight R, Mak T, Melino G, Agostini M.
PMID: 25997017
Cell Cycle. 2015;14(10):1611-2. doi: 10.1080/15384101.2015.1035968.

No abstract available.

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Velletri T, Romeo F, Tucci P, et al. GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation. Cell Cycle. 2015;14(10):1611-2doi: 10.1080/15384101.2015.1035968.
Velletri, T., Romeo, F., Tucci, P., Peschiaroli, A., Annicchiarico-Petruzzelli, M., Niklison-Chirou, M., Amelio, I., Knight, R., Mak, T., Melino, G., & Agostini, M. (2015). GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation. Cell cycle (Georgetown, Tex.), 14(10), 1611-2. https://doi.org/10.1080/15384101.2015.1035968
Velletri, Tania, et al. "GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation." Cell cycle (Georgetown, Tex.) vol. 14,10 (2015): 1611-2. doi: https://doi.org/10.1080/15384101.2015.1035968
Velletri T, Romeo F, Tucci P, Peschiaroli A, Annicchiarico-Petruzzelli M, Niklison-Chirou M, Amelio I, Knight R, Mak T, Melino G, Agostini M. GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation. Cell Cycle. 2015;14(10):1611-2. doi: 10.1080/15384101.2015.1035968. PMID: 25997017; PMCID: PMC4615081.
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Glass polymorphism in amorphous germanium probed by first-principles computer simulations.

Journal of physics. Condensed matter : an Institute of Physics journal

Mancini G, Celino M, Iesari F, Di Cicco A.
PMID: 26642884
J Phys Condens Matter. 2016 Jan 13;28(1):015401. doi: 10.1088/0953-8984/28/1/015401. Epub 2015 Dec 08.

The low-density (LDA) to high-density (HDA) transformation in amorphous Ge at high pressure is studied by first-principles molecular dynamics simulations in the framework of density functional theory. Previous experiments are accurately reproduced, including the presence of a well-defined LDA-HDA...

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Mancini G, Celino M, Iesari F, et al. Glass polymorphism in amorphous germanium probed by first-principles computer simulations. J Phys Condens Matter. 2015;28(1):015401doi: 10.1088/0953-8984/28/1/015401.
Mancini, G., Celino, M., Iesari, F., & Di Cicco, A. (2016). Glass polymorphism in amorphous germanium probed by first-principles computer simulations. Journal of physics. Condensed matter : an Institute of Physics journal, 28(1), 015401. https://doi.org/10.1088/0953-8984/28/1/015401
Mancini, G, et al. "Glass polymorphism in amorphous germanium probed by first-principles computer simulations." Journal of physics. Condensed matter : an Institute of Physics journal vol. 28,1 (2016): 015401. doi: https://doi.org/10.1088/0953-8984/28/1/015401
Mancini G, Celino M, Iesari F, Di Cicco A. Glass polymorphism in amorphous germanium probed by first-principles computer simulations. J Phys Condens Matter. 2016 Jan 13;28(1):015401. doi: 10.1088/0953-8984/28/1/015401. Epub 2015 Dec 08. PMID: 26642884.
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The Anterolateral Ligament: An Anatomic Study on Sex-Based Differences.

Orthopaedic journal of sports medicine

Daggett M, Helito C, Cullen M, Ockuly A, Busch K, Granite J, Wright B, Sonnery-Cottet B.
PMID: 28321423
Orthop J Sports Med. 2017 Feb 22;5(2):2325967116689387. doi: 10.1177/2325967116689387. eCollection 2017 Feb.

BACKGROUND: The anterolateral ligament (ALL) has been shown to have an important role in rotatory stability of the knee. While there is abundant research on sex-based differences related to anterior cruciate ligament (ACL) rupture, there is a paucity of...

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Daggett M, Helito C, Cullen M, et al. The Anterolateral Ligament: An Anatomic Study on Sex-Based Differences. Orthop J Sports Med. 2017;5(2):2325967116689387doi: 10.1177/2325967116689387.
Daggett, M., Helito, C., Cullen, M., Ockuly, A., Busch, K., Granite, J., Wright, B., & Sonnery-Cottet, B. (2017). The Anterolateral Ligament: An Anatomic Study on Sex-Based Differences. Orthopaedic journal of sports medicine, 5(2), 2325967116689387. https://doi.org/10.1177/2325967116689387
Daggett, Matt, et al. "The Anterolateral Ligament: An Anatomic Study on Sex-Based Differences." Orthopaedic journal of sports medicine vol. 5,2 (2017): 2325967116689387. doi: https://doi.org/10.1177/2325967116689387
Daggett M, Helito C, Cullen M, Ockuly A, Busch K, Granite J, Wright B, Sonnery-Cottet B. The Anterolateral Ligament: An Anatomic Study on Sex-Based Differences. Orthop J Sports Med. 2017 Feb 22;5(2):2325967116689387. doi: 10.1177/2325967116689387. eCollection 2017 Feb. PMID: 28321423; PMCID: PMC5347435.
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Myocardial infarction models in NOD/Scid mice for cell therapy research: permanent ischemia vs ischemia-reperfusion.

SpringerPlus

van Zuylen VL, den Haan MC, Roelofs H, Fibbe WE, Schalij MJ, Atsma DE.
PMID: 26185738
Springerplus. 2015 Jul 10;4:336. doi: 10.1186/s40064-015-1128-y. eCollection 2015.

Myocardial infarction animal studies are used to study disease mechanisms and new treatment options. Typically, myocardial infarction (MI) is induced by permanent occlusion of the left anterior descending artery. Since in MI patients coronary blood flow is often restored...

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van Zuylen VL, den Haan MC, Roelofs H, et al. Myocardial infarction models in NOD/Scid mice for cell therapy research: permanent ischemia vs ischemia-reperfusion. Springerplus. 2015;4:336doi: 10.1186/s40064-015-1128-y.
van Zuylen, V. L., den Haan, M. C., Roelofs, H., Fibbe, W. E., Schalij, M. J., & Atsma, D. E. (2015). Myocardial infarction models in NOD/Scid mice for cell therapy research: permanent ischemia vs ischemia-reperfusion. SpringerPlus, 4336. https://doi.org/10.1186/s40064-015-1128-y
van Zuylen, Vanessa-Leigh, et al. "Myocardial infarction models in NOD/Scid mice for cell therapy research: permanent ischemia vs ischemia-reperfusion." SpringerPlus vol. 4 (2015): 336. doi: https://doi.org/10.1186/s40064-015-1128-y
van Zuylen VL, den Haan MC, Roelofs H, Fibbe WE, Schalij MJ, Atsma DE. Myocardial infarction models in NOD/Scid mice for cell therapy research: permanent ischemia vs ischemia-reperfusion. Springerplus. 2015 Jul 10;4:336. doi: 10.1186/s40064-015-1128-y. eCollection 2015. PMID: 26185738; PMCID: PMC4498004.
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Genetic Variability and Host Specialization in the Latin American Clade of Ceratocystis fimbriata.

Phytopathology

Baker CJ, Harrington TC, Krauss U, Alfenas AC.
PMID: 18944327
Phytopathology. 2003 Oct;93(10):1274-84. doi: 10.1094/PHYTO.2003.93.10.1274.

ABSTRACT The Ceratocystis fimbriata complex includes many undescribed species that cause wilt and canker diseases of many economically important plants. Phylogenetic analyses of DNA sequences have delineated three geographic clades within Ceratocystis fimbriata. This study examined host specialization in...

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Baker CJ, Harrington TC, Krauss U, et al. Genetic Variability and Host Specialization in the Latin American Clade of Ceratocystis fimbriata. Phytopathology. 2003;93(10):1274-84doi: 10.1094/PHYTO.2003.93.10.1274.
Baker, C. J., Harrington, T. C., Krauss, U., & Alfenas, A. C. (2003). Genetic Variability and Host Specialization in the Latin American Clade of Ceratocystis fimbriata. Phytopathology, 93(10), 1274-84. https://doi.org/10.1094/PHYTO.2003.93.10.1274
Baker, Christine J, et al. "Genetic Variability and Host Specialization in the Latin American Clade of Ceratocystis fimbriata." Phytopathology vol. 93,10 (2003): 1274-84. doi: https://doi.org/10.1094/PHYTO.2003.93.10.1274
Baker CJ, Harrington TC, Krauss U, Alfenas AC. Genetic Variability and Host Specialization in the Latin American Clade of Ceratocystis fimbriata. Phytopathology. 2003 Oct;93(10):1274-84. doi: 10.1094/PHYTO.2003.93.10.1274. PMID: 18944327.
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c-myb down regulation is associated with apoptosis in human neuroblastoma cells.

Cell death and differentiation

Piacentini M, Raschellá G, Calabretta B, Melino G.
PMID: 17180021
Cell Death Differ. 1994;1(2):85-92.

The c-myb transcriptional regulator plays a crucial role in the control of several proliferative/differentiative processes in haematopoietic cells. Its expression and function is not lineage-restricted, since c-myb is also expressed in solid tumours such as neuroblastomas, where its transcription...

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Piacentini M, Raschellá G, Calabretta B, et al. c-myb down regulation is associated with apoptosis in human neuroblastoma cells. Cell Death Differ. 1994;1(2):85-92
Piacentini, M., Raschellá, G., Calabretta, B., & Melino, G. (1994). c-myb down regulation is associated with apoptosis in human neuroblastoma cells. Cell death and differentiation, 1(2), 85-92.
Piacentini, M, et al. "c-myb down regulation is associated with apoptosis in human neuroblastoma cells." Cell death and differentiation vol. 1,2 (1994): 85-92.
Piacentini M, Raschellá G, Calabretta B, Melino G. c-myb down regulation is associated with apoptosis in human neuroblastoma cells. Cell Death Differ. 1994;1(2):85-92. PMID: 17180021.
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Cell death in muscle pathology.

Cell death and differentiation

Lockshin RA, Knight RA, Melino G.
PMID: 17180026
Cell Death Differ. 1995 Oct;2(4):231-2.

No abstract available.

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Lockshin RA, Knight RA, Melino G. Cell death in muscle pathology. Cell Death Differ. 1995;2(4):231-2
Lockshin, R. A., Knight, R. A., & Melino, G. (1995). Cell death in muscle pathology. Cell death and differentiation, 2(4), 231-2.
Lockshin, R A, et al. "Cell death in muscle pathology." Cell death and differentiation vol. 2,4 (1995): 231-2.
Lockshin RA, Knight RA, Melino G. Cell death in muscle pathology. Cell Death Differ. 1995 Oct;2(4):231-2. PMID: 17180026.
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Coordination "oligomers" in self-assembly reactions of some "tritopic" picolinic dihydrazone ligands-mononuclear, dinuclear, hexanuclear, heptanuclear, and nonanuclear examples.

Inorganic chemistry

Niel V, Milway VA, Dawe LN, Grove H, Tandon SS, Abedin TS, Kelly TL, Spencer EC, Howard JA, Collins JL, Miller DO, Thompson LK.
PMID: 18076158
Inorg Chem. 2008 Jan 07;47(1):176-89. doi: 10.1021/ic7016787. Epub 2007 Dec 13.

"Tritopic" picolinic dihydrazone ligands with tridentate coordination pockets are designed to produce homoleptic [3 x 3] nonanuclear square grid complexes on reaction with transition-metal salts, and many structurally documented examples have been obtained with Mn(II), Cu(II), and Zn(II) ions....

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Niel V, Milway VA, Dawe LN, et al. Coordination "oligomers" in self-assembly reactions of some "tritopic" picolinic dihydrazone ligands-mononuclear, dinuclear, hexanuclear, heptanuclear, and nonanuclear examples. Inorg Chem. 2007;47(1):176-89doi: 10.1021/ic7016787.
Niel, V., Milway, V. A., Dawe, L. N., Grove, H., Tandon, S. S., Abedin, T. S., Kelly, T. L., Spencer, E. C., Howard, J. A., Collins, J. L., Miller, D. O., & Thompson, L. K. (2008). Coordination "oligomers" in self-assembly reactions of some "tritopic" picolinic dihydrazone ligands-mononuclear, dinuclear, hexanuclear, heptanuclear, and nonanuclear examples. Inorganic chemistry, 47(1), 176-89. https://doi.org/10.1021/ic7016787
Niel, Virginie, et al. "Coordination "oligomers" in self-assembly reactions of some "tritopic" picolinic dihydrazone ligands-mononuclear, dinuclear, hexanuclear, heptanuclear, and nonanuclear examples." Inorganic chemistry vol. 47,1 (2008): 176-89. doi: https://doi.org/10.1021/ic7016787
Niel V, Milway VA, Dawe LN, Grove H, Tandon SS, Abedin TS, Kelly TL, Spencer EC, Howard JA, Collins JL, Miller DO, Thompson LK. Coordination "oligomers" in self-assembly reactions of some "tritopic" picolinic dihydrazone ligands-mononuclear, dinuclear, hexanuclear, heptanuclear, and nonanuclear examples. Inorg Chem. 2008 Jan 07;47(1):176-89. doi: 10.1021/ic7016787. Epub 2007 Dec 13. PMID: 18076158.
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High accuracy plasma density measurement using hybrid Langmuir probe and microwave interferometer method.

The Review of scientific instruments

Deline C, Gilchrist BE, Dobson C, Jones JE, Chavers DG.
PMID: 18052471
Rev Sci Instrum. 2007 Nov;78(11):113504. doi: 10.1063/1.2813885.

High spatial resolution plasma density measurements have been taken as part of an investigation into magnetic nozzle physics at the NASA/MSFC Propulsion Research Center. These measurements utilized a Langmuir triple probe scanned across the measurement chord of either of...

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Deline C, Gilchrist BE, Dobson C, et al. High accuracy plasma density measurement using hybrid Langmuir probe and microwave interferometer method. Rev Sci Instrum. 2007;78(11):113504doi: 10.1063/1.2813885.
Deline, C., Gilchrist, B. E., Dobson, C., Jones, J. E., & Chavers, D. G. (2007). High accuracy plasma density measurement using hybrid Langmuir probe and microwave interferometer method. The Review of scientific instruments, 78(11), 113504. https://doi.org/10.1063/1.2813885
Deline, C, et al. "High accuracy plasma density measurement using hybrid Langmuir probe and microwave interferometer method." The Review of scientific instruments vol. 78,11 (2007): 113504. doi: https://doi.org/10.1063/1.2813885
Deline C, Gilchrist BE, Dobson C, Jones JE, Chavers DG. High accuracy plasma density measurement using hybrid Langmuir probe and microwave interferometer method. Rev Sci Instrum. 2007 Nov;78(11):113504. doi: 10.1063/1.2813885. PMID: 18052471.
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Global Assessment of Gastrointestinal Endoscopic Skills (GAGES): a valid measurement tool for technical skills in flexible endoscopy.

Surgical endoscopy

Vassiliou MC, Kaneva PA, Poulose BK, Dunkin BJ, Marks JM, Sadik R, Sroka G, Anvari M, Thaler K, Adrales GL, Hazey JW, Lightdale JR, Velanovich V, Swanstrom LL, Mellinger JD, Fried GM.
PMID: 20112113
Surg Endosc. 2010 Aug;24(8):1834-41. doi: 10.1007/s00464-010-0882-8. Epub 2010 Jan 29.

BACKGROUND: Simulators may improve the efficiency, safety, and quality of endoscopic training. However, no objective, reliable, and valid tool exists to assess clinical endoscopic skills. Such a tool to measure the outcomes of educational strategies is a necessity. This...

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Vassiliou MC, Kaneva PA, Poulose BK, et al. Global Assessment of Gastrointestinal Endoscopic Skills (GAGES): a valid measurement tool for technical skills in flexible endoscopy. Surg Endosc. 2010;24(8):1834-41doi: 10.1007/s00464-010-0882-8.
Vassiliou, M. C., Kaneva, P. A., Poulose, B. K., Dunkin, B. J., Marks, J. M., Sadik, R., Sroka, G., Anvari, M., Thaler, K., Adrales, G. L., Hazey, J. W., Lightdale, J. R., Velanovich, V., Swanstrom, L. L., Mellinger, J. D., & Fried, G. M. (2010). Global Assessment of Gastrointestinal Endoscopic Skills (GAGES): a valid measurement tool for technical skills in flexible endoscopy. Surgical endoscopy, 24(8), 1834-41. https://doi.org/10.1007/s00464-010-0882-8
Vassiliou, Melina C, et al. "Global Assessment of Gastrointestinal Endoscopic Skills (GAGES): a valid measurement tool for technical skills in flexible endoscopy." Surgical endoscopy vol. 24,8 (2010): 1834-41. doi: https://doi.org/10.1007/s00464-010-0882-8
Vassiliou MC, Kaneva PA, Poulose BK, Dunkin BJ, Marks JM, Sadik R, Sroka G, Anvari M, Thaler K, Adrales GL, Hazey JW, Lightdale JR, Velanovich V, Swanstrom LL, Mellinger JD, Fried GM. Global Assessment of Gastrointestinal Endoscopic Skills (GAGES): a valid measurement tool for technical skills in flexible endoscopy. Surg Endosc. 2010 Aug;24(8):1834-41. doi: 10.1007/s00464-010-0882-8. Epub 2010 Jan 29. PMID: 20112113.
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Pressure-induced cooperative bond rearrangement in a zinc imidazolate framework: a high-pressure single-crystal X-ray diffraction study.

Journal of the American Chemical Society

Spencer EC, Angel RJ, Ross NL, Hanson BE, Howard JA.
PMID: 19254021
J Am Chem Soc. 2009 Mar 25;131(11):4022-6. doi: 10.1021/ja808531m.

The pressure-dependent structural evolution of a neutral zinc-imidazolate framework [Zn(2)(C(3)H(3)N(2))(4)](n) (ZnIm) has been investigated. The as-synthesized three-dimensional ZnIm network (alpha-phase) crystallizes in the tetragonal space group I4(1)cd (a = 23.5028(4) A, c = 12.4607(3) A). The ZnIm crystal undergoes...

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Spencer EC, Angel RJ, Ross NL, et al. Pressure-induced cooperative bond rearrangement in a zinc imidazolate framework: a high-pressure single-crystal X-ray diffraction study. J Am Chem Soc. 2009;131(11):4022-6doi: 10.1021/ja808531m.
Spencer, E. C., Angel, R. J., Ross, N. L., Hanson, B. E., & Howard, J. A. (2009). Pressure-induced cooperative bond rearrangement in a zinc imidazolate framework: a high-pressure single-crystal X-ray diffraction study. Journal of the American Chemical Society, 131(11), 4022-6. https://doi.org/10.1021/ja808531m
Spencer, Elinor C, et al. "Pressure-induced cooperative bond rearrangement in a zinc imidazolate framework: a high-pressure single-crystal X-ray diffraction study." Journal of the American Chemical Society vol. 131,11 (2009): 4022-6. doi: https://doi.org/10.1021/ja808531m
Spencer EC, Angel RJ, Ross NL, Hanson BE, Howard JA. Pressure-induced cooperative bond rearrangement in a zinc imidazolate framework: a high-pressure single-crystal X-ray diffraction study. J Am Chem Soc. 2009 Mar 25;131(11):4022-6. doi: 10.1021/ja808531m. PMID: 19254021.
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Showing 1 to 12 of 437 entries