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Showing 1 to 7 of 7 entries
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The cytotoxicity of aflatoxin b1 in human lymphocytes.

Sultan Qaboos University medical journal

Al-Hammadi S, Marzouqi F, Al-Mansouri A, Shahin A, Al-Shamsi M, Mensah-Brown E, Souid AK.
PMID: 24516756
Sultan Qaboos Univ Med J. 2014 Feb;14(1):e65-71. doi: 10.12816/0003338. Epub 2014 Jan 27.

OBJECTIVES: Aflatoxin B1 (AFB1) is a naturally occurring carcinogenic and immunosuppressive compound. This study was designed to measure its toxic effects on human peripheral blood mononuclear cells (PBMC).METHODS: The study recruited 7 healthy volunteers. PBMC were isolated and cellular...

Use of Second Window ICG in spinal cord biopsy of a mildly contrast-enhancing lesion: Technical note and review of the literature.

Neuro-Chirurgie

Mensah-Brown KG, Germi JW, Quattrone F, Maloney-Wilensky E, Lee JYK, Chen HI, Schuster JM.
PMID: 34102223
Neurochirurgie. 2021 Jun 06; doi: 10.1016/j.neuchi.2021.05.007. Epub 2021 Jun 06.

INTRODUCTION: Indocyanine green (ICG) is commonly used to visualize cerebral vasculature, particularly in the management of cerebral aneurysms. There have also been attempts to use ICG for visualization of tumors. Injection of ICG followed by immediate fluorescence microscopy is...

Effects of circulatory arrest and cardiopulmonary bypass on cerebral autoregulation in neonatal swine.

Pediatric research

Padawer-Curry JA, Volk LE, Mavroudis CD, Ko TS, Morano VC, Busch DR, Rosenthal TM, Melchior RW, Shade BC, Schiavo KL, Boorady TW, Schmidt AL, Andersen KN, Breimann JS, Jahnavi J, Mensah-Brown KG, Yodh AG, Mascio CE, Kilbaugh TJ, Licht DJ, White BR, Baker WB.
PMID: 33947997
Pediatr Res. 2021 May 04; doi: 10.1038/s41390-021-01525-3. Epub 2021 May 04.

BACKGROUND: Cerebral autoregulation mechanisms help maintain adequate cerebral blood flow (CBF) despite changes in cerebral perfusion pressure. Impairment of cerebral autoregulation, during and after cardiopulmonary bypass (CPB), may increase risk of neurologic injury in neonates undergoing surgery. In this...

Higher O-GlcNAc Levels Are Associated with Defects in Progenitor Proliferation and Premature Neuronal Differentiation during .

Frontiers in cellular neuroscience

Parween S, Varghese DS, Ardah MT, Prabakaran AD, Mensah-Brown E, Emerald BS, Ansari SA.
PMID: 29311838
Front Cell Neurosci. 2017 Dec 21;11:415. doi: 10.3389/fncel.2017.00415. eCollection 2017.

The nutrient responsive O-GlcNAcylation is a dynamic post-translational protein modification found on several nucleocytoplasmic proteins. Previous studies have suggested that hyperglycemia induces the levels of total O-GlcNAcylation inside the cells. Hyperglycemia mediated increase in protein O-GlcNAcylation has been shown...

Non-invasive diffuse optical neuromonitoring during cardiopulmonary resuscitation predicts return of spontaneous circulation.

Scientific reports

Ko TS, Mavroudis CD, Morgan RW, Baker WB, Marquez AM, Boorady TW, Devarajan M, Lin Y, Roberts AL, Landis WP, Mensah-Brown K, Nadkarni VM, Berg RA, Sutton RM, Yodh AG, Licht DJ, Guo W, Kilbaugh TJ.
PMID: 33589662
Sci Rep. 2021 Feb 15;11(1):3828. doi: 10.1038/s41598-021-83270-5.

Neurologic injury is a leading cause of morbidity and mortality following pediatric cardiac arrest. In this study, we assess the feasibility of quantitative, non-invasive, frequency-domain diffuse optical spectroscopy (FD-DOS) neuromonitoring during cardiopulmonary resuscitation (CPR), and its predictive utility for...

Inequalities in Meningioma Survival: Results from the National Cancer Database.

Cureus

Yang AI, Mensah-Brown KG, Rinehart C, Fathy R, Hitti FL, Brant J, Lee JYK.
PMID: 32313745
Cureus. 2020 Mar 18;12(3):e7304. doi: 10.7759/cureus.7304.

Background Meningiomas are the second most common primary tumors of the central nervous system. However, there is a paucity of literature examining how healthcare, demographic, and socioeconomic factors impact patient outcomes. Methods We conducted a retrospective study of 65,812...

Antibody Reactivity to Merozoite Antigens in Ghanaian Adults Correlates With Growth Inhibitory Activity Against .

Open forum infectious diseases

Mensah-Brown HE, Aspeling-Jones H, Delimini RK, Asante KP, Amlabu E, Bah SY, Beeson JG, Wright GJ, Conway DJ, Awandare GA.
PMID: 31294045
Open Forum Infect Dis. 2019 May 28;6(7):ofz254. doi: 10.1093/ofid/ofz254. eCollection 2019 Jul.

METHODS: We assayed antibody reactivity against a panel of 9 recombinant antigens based on erythrocyte-binding antigen (EBA) and reticulocyte-like homolog (Rh) proteins in plasma from children with malaria and healthy adults residing in 3 endemic areas in Ghana using...

Showing 1 to 7 of 7 entries