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Showing 1 to 12 of 12 entries
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Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic.

EBioMedicine

Foley SB, Rios JJ, Mgbemena VE, Robinson LS, Hampel HL, Toland AE, Durham L, Ross TS.
PMID: 26023681
EBioMedicine. 2015 Jan;2(1):74-81. doi: 10.1016/j.ebiom.2014.12.003.

Despite the potential of whole-genome sequencing (WGS) to improve patient diagnosis and care, the empirical value of WGS in the cancer genetics clinic is unknown. We performed WGS on members of two cohorts of cancer genetics patients: those with

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Foley SB, Rios JJ, Mgbemena VE, et al. Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic. EBioMedicine. 2015;2(1):74-81doi: 10.1016/j.ebiom.2014.12.003.
Foley, S. B., Rios, J. J., Mgbemena, V. E., Robinson, L. S., Hampel, H. L., Toland, A. E., Durham, L., & Ross, T. S. (2015). Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic. EBioMedicine, 2(1), 74-81. https://doi.org/10.1016/j.ebiom.2014.12.003
Foley, Samantha B, et al. "Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic." EBioMedicine vol. 2,1 (2015): 74-81. doi: https://doi.org/10.1016/j.ebiom.2014.12.003
Foley SB, Rios JJ, Mgbemena VE, Robinson LS, Hampel HL, Toland AE, Durham L, Ross TS. Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic. EBioMedicine. 2015 Jan;2(1):74-81. doi: 10.1016/j.ebiom.2014.12.003. PMID: 26023681; PMCID: PMC4444225.
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Bartonella Endocarditis: A Missed Diagnosis in Medical Practice.

Cureus

Zhang Y, Verdecia J, Mgbemena O, Ravi M, Sands M.
PMID: 34900484
Cureus. 2021 Nov 06;13(11):e19309. doi: 10.7759/cureus.19309. eCollection 2021 Nov.

Here, we present the case of a 52-year-old patient who presented with fever, chills, and weight loss. Further workup revealed

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Zhang Y, Verdecia J, Mgbemena O, et al. Bartonella Endocarditis: A Missed Diagnosis in Medical Practice. Cureus. 2021;13(11):e19309doi: 10.7759/cureus.19309.
Zhang, Y., Verdecia, J., Mgbemena, O., Ravi, M., & Sands, M. (2021). Bartonella Endocarditis: A Missed Diagnosis in Medical Practice. Cureus, 13(11), e19309. https://doi.org/10.7759/cureus.19309
Zhang, Yixin, et al. "Bartonella Endocarditis: A Missed Diagnosis in Medical Practice." Cureus vol. 13,11 (2021): e19309. doi: https://doi.org/10.7759/cureus.19309
Zhang Y, Verdecia J, Mgbemena O, Ravi M, Sands M. Bartonella Endocarditis: A Missed Diagnosis in Medical Practice. Cureus. 2021 Nov 06;13(11):e19309. doi: 10.7759/cureus.19309. eCollection 2021 Nov. PMID: 34900484; PMCID: PMC8647862.
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Role of Diabetes Mellitus in Heart Failure With Preserved Ejection Fraction: A Review Article.

Cureus

Mgbemena O, Zhang Y, Velarde G.
PMID: 34926000
Cureus. 2021 Nov 09;13(11):e19398. doi: 10.7759/cureus.19398. eCollection 2021 Nov.

The pathophysiology of heart failure with preserved ejection fraction (HFpEF) is complex and poorly understood. There is a high prevalence of Diabetes Mellitus (DM) in patients with HFpEF, and the presence of DM has been shown to increase mortality...

Cite
Mgbemena O, Zhang Y, Velarde G. Role of Diabetes Mellitus in Heart Failure With Preserved Ejection Fraction: A Review Article. Cureus. 2021;13(11):e19398doi: 10.7759/cureus.19398.
Mgbemena, O., Zhang, Y., & Velarde, G. (2021). Role of Diabetes Mellitus in Heart Failure With Preserved Ejection Fraction: A Review Article. Cureus, 13(11), e19398. https://doi.org/10.7759/cureus.19398
Mgbemena, Okechukwu, et al. "Role of Diabetes Mellitus in Heart Failure With Preserved Ejection Fraction: A Review Article." Cureus vol. 13,11 (2021): e19398. doi: https://doi.org/10.7759/cureus.19398
Mgbemena O, Zhang Y, Velarde G. Role of Diabetes Mellitus in Heart Failure With Preserved Ejection Fraction: A Review Article. Cureus. 2021 Nov 09;13(11):e19398. doi: 10.7759/cureus.19398. eCollection 2021 Nov. PMID: 34926000; PMCID: PMC8654084.
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Prevalence of congenital malaria in minna, north central Nigeria.

Journal of tropical medicine

Omalu IC, Mgbemena C, Mgbemena A, Ayanwale V, Olayemi IK, Lateef A, Chukwuemeka VI.
PMID: 21876706
J Trop Med. 2012;2012:274142. doi: 10.1155/2012/274142. Epub 2011 Aug 14.

The study was designed to determine the true prevalence of congenital, cord, and placental malaria in General Hospital Minna, North Central Nigeria. Peripheral blood smears of near-term pregnant women, as well as the placental, cord, and peripheral blood smears...

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Omalu IC, Mgbemena C, Mgbemena A, et al. Prevalence of congenital malaria in minna, north central Nigeria. J Trop Med. 2011;2012:274142doi: 10.1155/2012/274142.
Omalu, I. C., Mgbemena, C., Mgbemena, A., Ayanwale, V., Olayemi, I. K., Lateef, A., & Chukwuemeka, V. I. (2012). Prevalence of congenital malaria in minna, north central Nigeria. Journal of tropical medicine, 2012274142. https://doi.org/10.1155/2012/274142
Omalu, Innocent Chukwuemeka James, et al. "Prevalence of congenital malaria in minna, north central Nigeria." Journal of tropical medicine vol. 2012 (2012): 274142. doi: https://doi.org/10.1155/2012/274142
Omalu IC, Mgbemena C, Mgbemena A, Ayanwale V, Olayemi IK, Lateef A, Chukwuemeka VI. Prevalence of congenital malaria in minna, north central Nigeria. J Trop Med. 2012;2012:274142. doi: 10.1155/2012/274142. Epub 2011 Aug 14. PMID: 21876706; PMCID: PMC3157756.
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Re-evaluating the role of BCR/ABL in chronic myelogenous leukemia.

Molecular & cellular oncology

Ross TS, Mgbemena VE.
PMID: 27308345
Mol Cell Oncol. 2014 Oct 29;1(3):e963450. doi: 10.4161/23723548.2014.963450. eCollection 2014.

Chronic myelogenous leukemia (CML) requires the BCR/ABL tyrosine kinase for disease onset and maintenance. As a result, CML can be successfully treated with tyrosine kinase inhibitors (TKIs) such as imatinib. Most patients are maintained in a disease-suppressed state on...

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Ross TS, Mgbemena VE. Re-evaluating the role of BCR/ABL in chronic myelogenous leukemia. Mol Cell Oncol. 2014;1(3):e963450doi: 10.4161/23723548.2014.963450.
Ross, T. S., & Mgbemena, V. E. (2014). Re-evaluating the role of BCR/ABL in chronic myelogenous leukemia. Molecular & cellular oncology, 1(3), e963450. https://doi.org/10.4161/23723548.2014.963450
Ross, Theodora S, and Mgbemena, Victoria E. "Re-evaluating the role of BCR/ABL in chronic myelogenous leukemia." Molecular & cellular oncology vol. 1,3 (2014): e963450. doi: https://doi.org/10.4161/23723548.2014.963450
Ross TS, Mgbemena VE. Re-evaluating the role of BCR/ABL in chronic myelogenous leukemia. Mol Cell Oncol. 2014 Oct 29;1(3):e963450. doi: 10.4161/23723548.2014.963450. eCollection 2014. PMID: 27308345; PMCID: PMC4904890.
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Functional Interaction of BRCA1 and CREBBP in Murine Hematopoiesis.

iScience

Holmstrom SR, Wijayatunge R, McCrum K, Mgbemena VE, Ross TS.
PMID: 31499338
iScience. 2019 Sep 27;19:809-820. doi: 10.1016/j.isci.2019.08.031. Epub 2019 Aug 26.

Both BRCA1 and CREBBP are tumor suppressor genes that are important for hematopoiesis. We have previously shown that mouse Brca1 is essential for hematopoietic stem cell (HSC) viability. In contrast to Brca1 deficiency, which results in pancytopenia, we report...

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Holmstrom SR, Wijayatunge R, McCrum K, et al. Functional Interaction of BRCA1 and CREBBP in Murine Hematopoiesis. iScience. 2019;19:809-820doi: 10.1016/j.isci.2019.08.031.
Holmstrom, S. R., Wijayatunge, R., McCrum, K., Mgbemena, V. E., & Ross, T. S. (2019). Functional Interaction of BRCA1 and CREBBP in Murine Hematopoiesis. iScience, 19809-820. https://doi.org/10.1016/j.isci.2019.08.031
Holmstrom, Sam R, et al. "Functional Interaction of BRCA1 and CREBBP in Murine Hematopoiesis." iScience vol. 19 (2019): 809-820. doi: https://doi.org/10.1016/j.isci.2019.08.031
Holmstrom SR, Wijayatunge R, McCrum K, Mgbemena VE, Ross TS. Functional Interaction of BRCA1 and CREBBP in Murine Hematopoiesis. iScience. 2019 Sep 27;19:809-820. doi: 10.1016/j.isci.2019.08.031. Epub 2019 Aug 26. PMID: 31499338; PMCID: PMC6734175.
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Relationship between handgrip strength and lung function in adults: a systematic review.

Physiotherapy theory and practice

Mgbemena N, Jones A, Leicht AS.
PMID: 33870831
Physiother Theory Pract. 2021 Apr 18;1-20. doi: 10.1080/09593985.2021.1901323. Epub 2021 Apr 18.

Handgrip strength (HGS) is a functional test that has been directly associated with lung function in some healthy populations; however, inconsistent findings have been reported for populations with chronic diseases. The aim of this study was to identify the...

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Mgbemena N, Jones A, Leicht AS. Relationship between handgrip strength and lung function in adults: a systematic review. Physiother Theory Pract. 2021;1-20doi: 10.1080/09593985.2021.1901323.
Mgbemena, N., Jones, A., & Leicht, A. S. (2021). Relationship between handgrip strength and lung function in adults: a systematic review. Physiotherapy theory and practice, 1-20. https://doi.org/10.1080/09593985.2021.1901323
Mgbemena, Nnamdi, et al. "Relationship between handgrip strength and lung function in adults: a systematic review." Physiotherapy theory and practice vol. (2021): 1-20. doi: https://doi.org/10.1080/09593985.2021.1901323
Mgbemena N, Jones A, Leicht AS. Relationship between handgrip strength and lung function in adults: a systematic review. Physiother Theory Pract. 2021 Apr 18;1-20. doi: 10.1080/09593985.2021.1901323. Epub 2021 Apr 18. PMID: 33870831.
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Genomic Fabric Remodeling in Metastatic Clear Cell Renal Cell Carcinoma (ccRCC): A New Paradigm and Proposal for a Personalized Gene Therapy Approach.

Cancers

Iacobas DA, Mgbemena VE, Iacobas S, Menezes KM, Wang H, Saganti PB.
PMID: 33302383
Cancers (Basel). 2020 Dec 08;12(12). doi: 10.3390/cancers12123678.

Published transcriptomic data from surgically removed metastatic clear cell renal cell carcinoma samples were analyzed from the genomic fabric paradigm (GFP) perspective to identify the best targets for gene therapy. GFP considers the transcriptome as a multi-dimensional mathematical object...

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Iacobas DA, Mgbemena VE, Iacobas S, et al. Genomic Fabric Remodeling in Metastatic Clear Cell Renal Cell Carcinoma (ccRCC): A New Paradigm and Proposal for a Personalized Gene Therapy Approach. Cancers (Basel). 2020;12(12)doi: 10.3390/cancers12123678.
Iacobas, D. A., Mgbemena, V. E., Iacobas, S., Menezes, K. M., Wang, H., & Saganti, P. B. (2020). Genomic Fabric Remodeling in Metastatic Clear Cell Renal Cell Carcinoma (ccRCC): A New Paradigm and Proposal for a Personalized Gene Therapy Approach. Cancers, 12(12), . https://doi.org/10.3390/cancers12123678
Iacobas, Dumitru A, et al. "Genomic Fabric Remodeling in Metastatic Clear Cell Renal Cell Carcinoma (ccRCC): A New Paradigm and Proposal for a Personalized Gene Therapy Approach." Cancers vol. 12,12 (2020). doi: https://doi.org/10.3390/cancers12123678
Iacobas DA, Mgbemena VE, Iacobas S, Menezes KM, Wang H, Saganti PB. Genomic Fabric Remodeling in Metastatic Clear Cell Renal Cell Carcinoma (ccRCC): A New Paradigm and Proposal for a Personalized Gene Therapy Approach. Cancers (Basel). 2020 Dec 08;12(12). doi: 10.3390/cancers12123678. PMID: 33302383; PMCID: PMC7762545.
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Bartonella Endocarditis: A Missed Diagnosis in Medical Practice.

Cureus

Zhang Y, Verdecia J, Mgbemena O, Ravi M, Sands M.
PMID: 34900484
Cureus. 2021 Nov 06;13(11):e19309. doi: 10.7759/cureus.19309. eCollection 2021 Nov.

Here, we present the case of a 52-year-old patient who presented with fever, chills, and weight loss. Further workup revealed

Cite
Zhang Y, Verdecia J, Mgbemena O, et al. Bartonella Endocarditis: A Missed Diagnosis in Medical Practice. Cureus. 2021;13(11):e19309doi: 10.7759/cureus.19309.
Zhang, Y., Verdecia, J., Mgbemena, O., Ravi, M., & Sands, M. (2021). Bartonella Endocarditis: A Missed Diagnosis in Medical Practice. Cureus, 13(11), e19309. https://doi.org/10.7759/cureus.19309
Zhang, Yixin, et al. "Bartonella Endocarditis: A Missed Diagnosis in Medical Practice." Cureus vol. 13,11 (2021): e19309. doi: https://doi.org/10.7759/cureus.19309
Zhang Y, Verdecia J, Mgbemena O, Ravi M, Sands M. Bartonella Endocarditis: A Missed Diagnosis in Medical Practice. Cureus. 2021 Nov 06;13(11):e19309. doi: 10.7759/cureus.19309. eCollection 2021 Nov. PMID: 34900484; PMCID: PMC8647862.
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Augmenting Traditional Cardiac and Medical Care in Africa via Telemedicine: A Pilot Study.

Cureus

Mgbemena ON, Sears I, Levine B.
PMID: 34603870
Cureus. 2021 Aug 27;13(8):e17483. doi: 10.7759/cureus.17483. eCollection 2021 Aug.

Background A critical decrease in the number of healthcare providers in developing countries is one of the major burdens to healthcare access in these countries. Many factors contribute to the lack of healthcare providers, including low doctor-to-population ratio, emigration...

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Mgbemena ON, Sears I, Levine B. Augmenting Traditional Cardiac and Medical Care in Africa via Telemedicine: A Pilot Study. Cureus. 2021;13(8):e17483doi: 10.7759/cureus.17483.
Mgbemena, O. N., Sears, I., & Levine, B. (2021). Augmenting Traditional Cardiac and Medical Care in Africa via Telemedicine: A Pilot Study. Cureus, 13(8), e17483. https://doi.org/10.7759/cureus.17483
Mgbemena, Okechukwu N, et al. "Augmenting Traditional Cardiac and Medical Care in Africa via Telemedicine: A Pilot Study." Cureus vol. 13,8 (2021): e17483. doi: https://doi.org/10.7759/cureus.17483
Mgbemena ON, Sears I, Levine B. Augmenting Traditional Cardiac and Medical Care in Africa via Telemedicine: A Pilot Study. Cureus. 2021 Aug 27;13(8):e17483. doi: 10.7759/cureus.17483. eCollection 2021 Aug. PMID: 34603870; PMCID: PMC8476115.
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Community acceptance and willingness to pay for hypothetical COVID-19 vaccines in a developing country: a web-based nationwide study in Nigeria.

The Pan African medical journal

Okafor UG, Isah A, Onuh JC, Mgbemena CB, Ubaka CM.
PMID: 34887986
Pan Afr Med J. 2021 Oct 21;40:112. doi: 10.11604/pamj.2021.40.112.27780. eCollection 2021.

INTRODUCTION: some promising COVID-19 vaccines are soon to be available but getting the African community to accept them may be challenging. This study assessed the acceptability and willingness to pay (WTP) for hypothetical COVID-19 vaccines among Nigerians.METHODS: a cross-sectional,...

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Okafor UG, Isah A, Onuh JC, et al. Community acceptance and willingness to pay for hypothetical COVID-19 vaccines in a developing country: a web-based nationwide study in Nigeria. Pan Afr Med J. 2021;40:112doi: 10.11604/pamj.2021.40.112.27780.
Okafor, U. G., Isah, A., Onuh, J. C., Mgbemena, C. B., & Ubaka, C. M. (2021). Community acceptance and willingness to pay for hypothetical COVID-19 vaccines in a developing country: a web-based nationwide study in Nigeria. The Pan African medical journal, 40112. https://doi.org/10.11604/pamj.2021.40.112.27780
Okafor, Ukamaka Gladys, et al. "Community acceptance and willingness to pay for hypothetical COVID-19 vaccines in a developing country: a web-based nationwide study in Nigeria." The Pan African medical journal vol. 40 (2021): 112. doi: https://doi.org/10.11604/pamj.2021.40.112.27780
Okafor UG, Isah A, Onuh JC, Mgbemena CB, Ubaka CM. Community acceptance and willingness to pay for hypothetical COVID-19 vaccines in a developing country: a web-based nationwide study in Nigeria. Pan Afr Med J. 2021 Oct 21;40:112. doi: 10.11604/pamj.2021.40.112.27780. eCollection 2021. PMID: 34887986; PMCID: PMC8627134.
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Role of Diabetes Mellitus in Heart Failure With Preserved Ejection Fraction: A Review Article.

Cureus

Mgbemena O, Zhang Y, Velarde G.
PMID: 34926000
Cureus. 2021 Nov 09;13(11):e19398. doi: 10.7759/cureus.19398. eCollection 2021 Nov.

The pathophysiology of heart failure with preserved ejection fraction (HFpEF) is complex and poorly understood. There is a high prevalence of Diabetes Mellitus (DM) in patients with HFpEF, and the presence of DM has been shown to increase mortality...

Cite
Mgbemena O, Zhang Y, Velarde G. Role of Diabetes Mellitus in Heart Failure With Preserved Ejection Fraction: A Review Article. Cureus. 2021;13(11):e19398doi: 10.7759/cureus.19398.
Mgbemena, O., Zhang, Y., & Velarde, G. (2021). Role of Diabetes Mellitus in Heart Failure With Preserved Ejection Fraction: A Review Article. Cureus, 13(11), e19398. https://doi.org/10.7759/cureus.19398
Mgbemena, Okechukwu, et al. "Role of Diabetes Mellitus in Heart Failure With Preserved Ejection Fraction: A Review Article." Cureus vol. 13,11 (2021): e19398. doi: https://doi.org/10.7759/cureus.19398
Mgbemena O, Zhang Y, Velarde G. Role of Diabetes Mellitus in Heart Failure With Preserved Ejection Fraction: A Review Article. Cureus. 2021 Nov 09;13(11):e19398. doi: 10.7759/cureus.19398. eCollection 2021 Nov. PMID: 34926000; PMCID: PMC8654084.
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Showing 1 to 12 of 12 entries