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Showing 1 to 12 of 59 entries
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Circulating nucleosomes as epigenetic biomarkers in pancreatic cancer.

Clinical epigenetics

Bauden M, Pamart D, Ansari D, Herzog M, Eccleston M, Micallef J, Andersson B, Andersson R.
PMID: 26451166
Clin Epigenetics. 2015 Oct 07;7:106. doi: 10.1186/s13148-015-0139-4. eCollection 2015.

BACKGROUND: To improve the prognosis of patients with pancreatic cancer, new biomarkers are required for earlier, pre-symptomatic diagnosis. Epigenetic mutations take place at the earliest stages of tumorigenesis and therefore offer new approaches for detecting and diagnosing disease. Nucleosomes...

Effect of desipramine on patients with breathing disorders in RETT syndrome.

Annals of clinical and translational neurology

Mancini J, Dubus JC, Jouve E, Roux JC, Franco P, Lagrue E, Castelnau P, Cances C, Chaix Y, Rougeot-Jung C, Cornu C, Desportes V, Vallée L, Bahi-Buisson N, Truillet R, Attolini L, Villard L, Blin O, Micallef J.
PMID: 29468173
Ann Clin Transl Neurol. 2017 Dec 27;5(2):118-127. doi: 10.1002/acn3.468. eCollection 2018 Feb.

OBJECTIVE: Rett Syndrome (RTT) is a severe neurodevelopmental condition with breathing disorders, affecting around one in 10,000 female births. Desipramine, a noradrenaline reuptake inhibitor, reduced the number of apneas in Mecp2-deficient mice, a model of RTT. We planned a...

Erratum to: An exploratory randomised double-blind and placebo-controlled phase 2 study of a combination of baclofen, naltrexone and sorbitol (PXT3003) in patients with Charcot-Marie-Tooth disease type 1A.

Orphanet journal of rare diseases

Attarian S, Vallat JM, Magy L, Funalot B, Gonnaud PM, Lacour A, Péréon Y, Dubourg O, Pouget J, Micallef J, Franques J, Lefebvre MN, Ghorab K, Al-Moussawi M, Tiffreau V, Preudhomme M, Magot A, Leclair-Visonneau L, Stojkovic T, Bossi L, Lehert P, Gilbert W, Bertrand V, Mandel J, Milet A, Hajj R, Boudiaf L, Scart-Grès C, Nabirotchkin S, Guedj M, Chumakov I, Cohen D.
PMID: 27387831
Orphanet J Rare Dis. 2016 Jul 07;11(1):92. doi: 10.1186/s13023-016-0463-6.

No abstract available.

Warning on increased serious health complications related to non-medical use of nitrous oxide.

Therapie

, Micallef J, Mallaret M, Lapeyre-Mestre M, Daveluy A, Victorri-Vigneau C, Peyrière H, Debruyne D, Deheul S, Bordet R, Chevallier C, Perault-Pochat MC, Le Boisselier R, Libert F, Chaouachi L, Gillet P.
PMID: 32063400
Therapie. 2021 Sep-Oct;76(5):478-479. doi: 10.1016/j.therap.2020.01.002. Epub 2020 Jan 17.

No abstract available.

Features of inflammatory heart reactions following mRNA COVID-19 vaccination at a global level.

Clinical pharmacology and therapeutics

Chouchana L, Blet A, Al-Khalaf M, Kafil TS, Nair G, Robblee J, Drici MD, Valnet-Rabier MB, Micallef J, Salvo F, Treluyer JM, Liu PP.
PMID: 34860360
Clin Pharmacol Ther. 2021 Dec 03; doi: 10.1002/cpt.2499. Epub 2021 Dec 03.

Myocarditis and pericarditis may constitute adverse reactions of mRNA COVID-19 vaccines. This study aimed to document these reactions and to assess the association with patient sex and age. This is as an observational retrospective study using a case-non-case design...

Antidepressants abuse in subjects with opioid use disorders: A 10-year study in the French OPPIDUM program.

Fundamental & clinical pharmacology

Dumonceau RG, Soeiro T, Lacroix C, Giocanti A, Frauger É, Mezaache S, Micallef J.
PMID: 34837277
Fundam Clin Pharmacol. 2021 Nov 27; doi: 10.1111/fcp.12738. Epub 2021 Nov 27.

Accumulating evidence shows that some antidepressants are abused for their psychostimulant effects, but the extent of antidepressants abuse is unknown in subjects with opioid use disorders (OUD). The objective of this work is to assess the prevalence of antidepressant...

Design of an Intramuscular Injection Simulator: Accommodating Cultural Differences.

Cureus

Micallef J, Lin AC, Arutiunian A, Dubrowski A.
PMID: 34820235
Cureus. 2021 Oct 22;13(10):e18980. doi: 10.7759/cureus.18980. eCollection 2021 Oct.

We had developed an inexpensive intramuscular (IM) injection simulator and gathered feedback from Canadian hospital-based practicing nurses about the design features of the simulator. While the feedback critiqued the density of the simulator as being too stiff and suggested...

A 13-Year National Monitoring Study to Assess Narcotic Prescriptions and Indications (2007-2019).

Drug safety

Perri-Plandé J, Miremont-Salamé G, Micallef J, Herman C, Baumevieille M, Abriat F, Lapeyre-Mestre M, Haramburu F, Daveluy A.
PMID: 34714529
Drug Saf. 2021 Oct 29; doi: 10.1007/s40264-021-01124-5. Epub 2021 Oct 29.

INTRODUCTION: Analgesics are among the most widely used drugs worldwide. This study describes the population treated with narcotic analgesics, their therapeutic indications and how the data have evolved over a decade.METHODS: A cross-sectional, national, multicentre survey study was conducted...

Adverse drug reaction monitoring: Doing it the French way - Act II.

Therapie

Soeiro T, Lacroix C, Micallef J.
PMID: 33190850
Therapie. 2021 Sep-Oct;76(5):385-387. doi: 10.1016/j.therap.2020.11.002. Epub 2020 Nov 06.

No abstract available.

Serious Neurological Adverse Events of Ceftriaxone.

Antibiotics (Basel, Switzerland)

Lacroix C, Bera-Jonville AP, Montastruc F, Velly L, Micallef J, Guilhaumou R.
PMID: 34066591
Antibiotics (Basel). 2021 May 06;10(5). doi: 10.3390/antibiotics10050540.

We described ceftriaxone-induced CNS adverse events through the largest case series of Adverse Drug Reactions (ADRs) reports, from 1995 to 2017, using the French Pharmacovigilance Database. In total, 152 cases of serious CNS ADRs were analyzed; 112 patients were...

A 13-Year National Monitoring Study to Assess Narcotic Prescriptions and Indications (2007-2019).

Drug safety

Perri-Plandé J, Miremont-Salamé G, Micallef J, Herman C, Baumevieille M, Abriat F, Lapeyre-Mestre M, Haramburu F, Daveluy A.
PMID: 34714529
Drug Saf. 2022 Jan;45(1):37-44. doi: 10.1007/s40264-021-01124-5. Epub 2021 Oct 29.

INTRODUCTION: Analgesics are among the most widely used drugs worldwide. This study describes the population treated with narcotic analgesics, their therapeutic indications and how the data have evolved over a decade.METHODS: A cross-sectional, national, multicentre survey study was conducted...

[Not Available].

Therapie

Dhainaut JF, Bassompierre F, Misse C, Diebolt V, Pouletty-Lefèbvre B, Baker A, Borel T, Braunstein D, Demotes J, François B, Huet S, Micallef J, Molon A, Rascol O, Ravoire S, Schwartz B, Donne de N, Fusaï G, Pouletty P, Vicaut E.
PMID: 27393399
Therapie. 2015 Jan-Feb;70(1):95-102. doi: 10.2515/therapie/2014232.

No abstract available.

Showing 1 to 12 of 59 entries