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Stem Cell Therapy for Treatment of Ocular Disorders.

Stem cells international

Sivan PP, Syed S, Mok PL, Higuchi A, Murugan K, Alarfaj AA, Munusamy MA, Awang Hamat R, Umezawa A, Kumar S.
PMID: 27293447
Stem Cells Int. 2016;2016:8304879. doi: 10.1155/2016/8304879. Epub 2016 May 15.

Sustenance of visual function is the ultimate focus of ophthalmologists. Failure of complete recovery of visual function and complications that follow conventional treatments have shifted search to a new form of therapy using stem cells. Stem cell progenitors play...

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Sivan PP, Syed S, Mok PL, et al. Stem Cell Therapy for Treatment of Ocular Disorders. Stem Cells Int. 2016;2016:8304879doi: 10.1155/2016/8304879.
Sivan, P. P., Syed, S., Mok, P. L., Higuchi, A., Murugan, K., Alarfaj, A. A., Munusamy, M. A., Awang Hamat, R., Umezawa, A., & Kumar, S. (2016). Stem Cell Therapy for Treatment of Ocular Disorders. Stem cells international, 20168304879. https://doi.org/10.1155/2016/8304879
Sivan, Padma Priya, et al. "Stem Cell Therapy for Treatment of Ocular Disorders." Stem cells international vol. 2016 (2016): 8304879. doi: https://doi.org/10.1155/2016/8304879
Sivan PP, Syed S, Mok PL, Higuchi A, Murugan K, Alarfaj AA, Munusamy MA, Awang Hamat R, Umezawa A, Kumar S. Stem Cell Therapy for Treatment of Ocular Disorders. Stem Cells Int. 2016;2016:8304879. doi: 10.1155/2016/8304879. Epub 2016 May 15. PMID: 27293447; PMCID: PMC4884591.
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Isolation and kinetic characterisation of hydrophobically distinct populations of form I Rubisco.

Plant methods

O'Donnelly K, Zhao G, Patel P, Butt MS, Mak LH, Kretschmer S, Woscholski R, Barter LM.
PMID: 24987448
Plant Methods. 2014 Jun 12;10:17. doi: 10.1186/1746-4811-10-17. eCollection 2014.

BACKGROUND: Rubisco (Ribulose-1,5-bisphosphate carboxylase/oxygenase) is a Calvin Cycle enzyme involved in CO2 assimilation. It is thought to be a major cause of photosynthetic inefficiency, suffering from both a slow catalytic rate and lack of specificity due to a competing...

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O'Donnelly K, Zhao G, Patel P, et al. Isolation and kinetic characterisation of hydrophobically distinct populations of form I Rubisco. Plant Methods. 2014;10:17doi: 10.1186/1746-4811-10-17.
O'Donnelly, K., Zhao, G., Patel, P., Butt, M. S., Mak, L. H., Kretschmer, S., Woscholski, R., & Barter, L. M. (2014). Isolation and kinetic characterisation of hydrophobically distinct populations of form I Rubisco. Plant methods, 1017. https://doi.org/10.1186/1746-4811-10-17
O'Donnelly, Kerry, et al. "Isolation and kinetic characterisation of hydrophobically distinct populations of form I Rubisco." Plant methods vol. 10 (2014): 17. doi: https://doi.org/10.1186/1746-4811-10-17
O'Donnelly K, Zhao G, Patel P, Butt MS, Mak LH, Kretschmer S, Woscholski R, Barter LM. Isolation and kinetic characterisation of hydrophobically distinct populations of form I Rubisco. Plant Methods. 2014 Jun 12;10:17. doi: 10.1186/1746-4811-10-17. eCollection 2014. PMID: 24987448; PMCID: PMC4076768.
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Storage of 500 high-resolution holograms in a LiNbO(3) crystal.

Optics letters

Mok FH, Tackitt MC, Stoll HM.
PMID: 19774013
Opt Lett. 1991 Apr 15;16(8):605-7. doi: 10.1364/ol.16.000605.

We have recorded (at room temperature) as many as 500 high-resolution, uniformly diffracting volume holograms in a single Fe-doped LiNbO(3) crystal. The holograms were stored by angularly multiplexing a plane-wave reference beam. The graphical procedure that we used to...

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Mok FH, Tackitt MC, Stoll HM. Storage of 500 high-resolution holograms in a LiNbO(3) crystal. Opt Lett. 1991;16(8):605-7doi: 10.1364/ol.16.000605.
Mok, F. H., Tackitt, M. C., & Stoll, H. M. (1991). Storage of 500 high-resolution holograms in a LiNbO(3) crystal. Optics letters, 16(8), 605-7. https://doi.org/10.1364/ol.16.000605
Mok, F H, et al. "Storage of 500 high-resolution holograms in a LiNbO(3) crystal." Optics letters vol. 16,8 (1991): 605-7. doi: https://doi.org/10.1364/ol.16.000605
Mok FH, Tackitt MC, Stoll HM. Storage of 500 high-resolution holograms in a LiNbO(3) crystal. Opt Lett. 1991 Apr 15;16(8):605-7. doi: 10.1364/ol.16.000605. PMID: 19774013.
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Human Blood CD1c.

Frontiers in immunology

Leal Rojas IM, Mok WH, Pearson FE, Minoda Y, Kenna TJ, Barnard RT, Radford KJ.
PMID: 28878767
Front Immunol. 2017 Aug 17;8:971. doi: 10.3389/fimmu.2017.00971. eCollection 2017.

Dendritic cells (DC) initiate the differentiation of CD4

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Leal Rojas IM, Mok WH, Pearson FE, et al. Human Blood CD1c. Front Immunol. 2017;8:971doi: 10.3389/fimmu.2017.00971.
Leal Rojas, I. M., Mok, W. H., Pearson, F. E., Minoda, Y., Kenna, T. J., Barnard, R. T., & Radford, K. J. (2017). Human Blood CD1c. Frontiers in immunology, 8971. https://doi.org/10.3389/fimmu.2017.00971
Leal Rojas, Ingrid M, et al. "Human Blood CD1c." Frontiers in immunology vol. 8 (2017): 971. doi: https://doi.org/10.3389/fimmu.2017.00971
Leal Rojas IM, Mok WH, Pearson FE, Minoda Y, Kenna TJ, Barnard RT, Radford KJ. Human Blood CD1c. Front Immunol. 2017 Aug 17;8:971. doi: 10.3389/fimmu.2017.00971. eCollection 2017. PMID: 28878767; PMCID: PMC5572390.
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Make it SIMPLE: enhanced shock management by focused cardiac ultrasound.

Journal of intensive care

Mok KL.
PMID: 27529027
J Intensive Care. 2016 Aug 15;4:51. doi: 10.1186/s40560-016-0176-x. eCollection 2016.

BACKGROUND: Shock is a spectrum of circulatory failure that, if not properly managed, would lead to high mortality. Special diagnostic and treatment strategies are essential to save lives. However, clinical and laboratory findings are always non-specific, resulting in clinical...

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Mok KL. Make it SIMPLE: enhanced shock management by focused cardiac ultrasound. J Intensive Care. 2016;4:51doi: 10.1186/s40560-016-0176-x.
Mok, K. L. (2016). Make it SIMPLE: enhanced shock management by focused cardiac ultrasound. Journal of intensive care, 451. https://doi.org/10.1186/s40560-016-0176-x
Mok, Ka Leung. "Make it SIMPLE: enhanced shock management by focused cardiac ultrasound." Journal of intensive care vol. 4 (2016): 51. doi: https://doi.org/10.1186/s40560-016-0176-x
Mok KL. Make it SIMPLE: enhanced shock management by focused cardiac ultrasound. J Intensive Care. 2016 Aug 15;4:51. doi: 10.1186/s40560-016-0176-x. eCollection 2016. PMID: 27529027; PMCID: PMC4983798.
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Evaluation of plasma tau and neurofilament light chain biomarkers in a 12-year clinical cohort of human prion diseases.

Molecular psychiatry

Thompson AGB, Anastasiadis P, Druyeh R, Whitworth I, Nayak A, Nihat A, Mok TH, Rudge P, Wadsworth JDF, Rohrer J, Schott JM, Heslegrave A, Zetterberg H, Collinge J, Jackson GS, Mead S.
PMID: 33674752
Mol Psychiatry. 2021 Oct;26(10):5955-5966. doi: 10.1038/s41380-021-01045-w. Epub 2021 Mar 05.

Prion diseases are fatal neurodegenerative conditions with highly accurate CSF and imaging diagnostic tests, but major unmet needs for blood biomarkers. Using ultrasensitive immuno-assays, we measured tau and neurofilament light chain (NfL) protein concentrations in 709 plasma samples taken...

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Thompson AGB, Anastasiadis P, Druyeh R, et al. Evaluation of plasma tau and neurofilament light chain biomarkers in a 12-year clinical cohort of human prion diseases. Mol Psychiatry. 2021;26(10):5955-5966doi: 10.1038/s41380-021-01045-w.
Thompson, A. G. B., Anastasiadis, P., Druyeh, R., Whitworth, I., Nayak, A., Nihat, A., Mok, T. H., Rudge, P., Wadsworth, J. D. F., Rohrer, J., Schott, J. M., Heslegrave, A., Zetterberg, H., Collinge, J., Jackson, G. S., & Mead, S. (2021). Evaluation of plasma tau and neurofilament light chain biomarkers in a 12-year clinical cohort of human prion diseases. Molecular psychiatry, 26(10), 5955-5966. https://doi.org/10.1038/s41380-021-01045-w
Thompson, Andrew G B, et al. "Evaluation of plasma tau and neurofilament light chain biomarkers in a 12-year clinical cohort of human prion diseases." Molecular psychiatry vol. 26,10 (2021): 5955-5966. doi: https://doi.org/10.1038/s41380-021-01045-w
Thompson AGB, Anastasiadis P, Druyeh R, Whitworth I, Nayak A, Nihat A, Mok TH, Rudge P, Wadsworth JDF, Rohrer J, Schott JM, Heslegrave A, Zetterberg H, Collinge J, Jackson GS, Mead S. Evaluation of plasma tau and neurofilament light chain biomarkers in a 12-year clinical cohort of human prion diseases. Mol Psychiatry. 2021 Oct;26(10):5955-5966. doi: 10.1038/s41380-021-01045-w. Epub 2021 Mar 05. PMID: 33674752.
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Dinitrogen Activation and Functionalization by Heteronuclear Metal Cluster Anions FeV.

The journal of physical chemistry letters

Mou LH, Li Y, Li ZY, Liu QY, Ren Y, Chen H, He SG.
PMID: 33179926
J Phys Chem Lett. 2020 Dec 03;11(23):9990-9994. doi: 10.1021/acs.jpclett.0c02921. Epub 2020 Nov 12.

It is of great importance to study the mechanisms to activate dinitrogen (N

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Mou LH, Li Y, Li ZY, et al. Dinitrogen Activation and Functionalization by Heteronuclear Metal Cluster Anions FeV. J Phys Chem Lett. 2020;11(23):9990-9994doi: 10.1021/acs.jpclett.0c02921.
Mou, L. H., Li, Y., Li, Z. Y., Liu, Q. Y., Ren, Y., Chen, H., & He, S. G. (2020). Dinitrogen Activation and Functionalization by Heteronuclear Metal Cluster Anions FeV. The journal of physical chemistry letters, 11(23), 9990-9994. https://doi.org/10.1021/acs.jpclett.0c02921
Mou, Li-Hui, et al. "Dinitrogen Activation and Functionalization by Heteronuclear Metal Cluster Anions FeV." The journal of physical chemistry letters vol. 11,23 (2020): 9990-9994. doi: https://doi.org/10.1021/acs.jpclett.0c02921
Mou LH, Li Y, Li ZY, Liu QY, Ren Y, Chen H, He SG. Dinitrogen Activation and Functionalization by Heteronuclear Metal Cluster Anions FeV. J Phys Chem Lett. 2020 Dec 03;11(23):9990-9994. doi: 10.1021/acs.jpclett.0c02921. Epub 2020 Nov 12. PMID: 33179926.
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Work-related factors on mental health among migrant factory workers in china: Application of the Demand-Control and Effort-Reward Imbalance Model.

Health & social care in the community

Mo PKH, Cheng Y, Lau JTF.
PMID: 32989898
Health Soc Care Community. 2020 Sep 28; doi: 10.1111/hsc.13176. Epub 2020 Sep 28.

Mental health problems are prevalent among migrant workers in China. The present study examined the prevalence of mental health problems (depression, anxiety and suicidal ideation) among migrant workers in China, and identified the work-related factors associated with their mental...

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Mo PKH, Cheng Y, Lau JTF. Work-related factors on mental health among migrant factory workers in china: Application of the Demand-Control and Effort-Reward Imbalance Model. Health Soc Care Community. 2020;doi: 10.1111/hsc.13176.
Mo, P. K. H., Cheng, Y., & Lau, J. T. F. (2020). Work-related factors on mental health among migrant factory workers in china: Application of the Demand-Control and Effort-Reward Imbalance Model. Health & social care in the community, . https://doi.org/10.1111/hsc.13176
Mo, Phoenix K H, et al. "Work-related factors on mental health among migrant factory workers in china: Application of the Demand-Control and Effort-Reward Imbalance Model." Health & social care in the community vol. (2020). doi: https://doi.org/10.1111/hsc.13176
Mo PKH, Cheng Y, Lau JTF. Work-related factors on mental health among migrant factory workers in china: Application of the Demand-Control and Effort-Reward Imbalance Model. Health Soc Care Community. 2020 Sep 28; doi: 10.1111/hsc.13176. Epub 2020 Sep 28. PMID: 32989898.
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Optimal Dosing of Meropenem in a Small Cohort of Critically Ill Children Receiving Continuous Renal Replacement Therapy.

Journal of clinical pharmacology

Tan WW, Watt KM, Boakye-Agyeman F, Cohen-Wolkowiez M, Mok YH, Yung CF, Chan YH.
PMID: 33314163
J Clin Pharmacol. 2021 Jun;61(6):744-754. doi: 10.1002/jcph.1798. Epub 2021 Jan 12.

Severe sepsis is an important cause of mortality and morbidity in critically ill children. Meropenem is a broad-spectrum antibiotic commonly used to treat sepsis. Current meropenem dosage recommendations for children on continuous renal replacement therapy are extrapolated from pharmacokinetic...

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Tan WW, Watt KM, Boakye-Agyeman F, et al. Optimal Dosing of Meropenem in a Small Cohort of Critically Ill Children Receiving Continuous Renal Replacement Therapy. J Clin Pharmacol. 2021;61(6):744-754doi: 10.1002/jcph.1798.
Tan, W. W., Watt, K. M., Boakye-Agyeman, F., Cohen-Wolkowiez, M., Mok, Y. H., Yung, C. F., & Chan, Y. H. (2021). Optimal Dosing of Meropenem in a Small Cohort of Critically Ill Children Receiving Continuous Renal Replacement Therapy. Journal of clinical pharmacology, 61(6), 744-754. https://doi.org/10.1002/jcph.1798
Tan, Wei Wei, et al. "Optimal Dosing of Meropenem in a Small Cohort of Critically Ill Children Receiving Continuous Renal Replacement Therapy." Journal of clinical pharmacology vol. 61,6 (2021): 744-754. doi: https://doi.org/10.1002/jcph.1798
Tan WW, Watt KM, Boakye-Agyeman F, Cohen-Wolkowiez M, Mok YH, Yung CF, Chan YH. Optimal Dosing of Meropenem in a Small Cohort of Critically Ill Children Receiving Continuous Renal Replacement Therapy. J Clin Pharmacol. 2021 Jun;61(6):744-754. doi: 10.1002/jcph.1798. Epub 2021 Jan 12. PMID: 33314163; PMCID: PMC8089047.
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Transplanted Erythropoietin-Expressing Mesenchymal Stem Cells Promote Pro-survival Gene Expression and Protect Photoreceptors From Sodium Iodate-Induced Cytotoxicity in a Retinal Degeneration Model.

Frontiers in cell and developmental biology

Koh AE, Alsaeedi HA, Rashid MBA, Lam C, Harun MHN, Ng MH, Mohd Isa H, Then KY, Bastion MC, Farhana A, Khursheed Alam M, Subbiah SK, Mok PL.
PMID: 33987180
Front Cell Dev Biol. 2021 Apr 27;9:652017. doi: 10.3389/fcell.2021.652017. eCollection 2021.

Mesenchymal stem cells (MSC) are highly regarded as a potential treatment for retinal degenerative disorders like retinitis pigmentosa and age-related macular degeneration. However, donor cell heterogeneity and inconsistent protocols for transplantation have led to varied outcomes in clinical trials....

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Koh AE, Alsaeedi HA, Rashid MBA, et al. Transplanted Erythropoietin-Expressing Mesenchymal Stem Cells Promote Pro-survival Gene Expression and Protect Photoreceptors From Sodium Iodate-Induced Cytotoxicity in a Retinal Degeneration Model. Front Cell Dev Biol. 2021;9:652017doi: 10.3389/fcell.2021.652017.
Koh, A. E., Alsaeedi, H. A., Rashid, M. B. A., Lam, C., Harun, M. H. N., Ng, M. H., Mohd Isa, H., Then, K. Y., Bastion, M. C., Farhana, A., Khursheed Alam, M., Subbiah, S. K., & Mok, P. L. (2021). Transplanted Erythropoietin-Expressing Mesenchymal Stem Cells Promote Pro-survival Gene Expression and Protect Photoreceptors From Sodium Iodate-Induced Cytotoxicity in a Retinal Degeneration Model. Frontiers in cell and developmental biology, 9652017. https://doi.org/10.3389/fcell.2021.652017
Koh, Avin Ee-Hwan, et al. "Transplanted Erythropoietin-Expressing Mesenchymal Stem Cells Promote Pro-survival Gene Expression and Protect Photoreceptors From Sodium Iodate-Induced Cytotoxicity in a Retinal Degeneration Model." Frontiers in cell and developmental biology vol. 9 (2021): 652017. doi: https://doi.org/10.3389/fcell.2021.652017
Koh AE, Alsaeedi HA, Rashid MBA, Lam C, Harun MHN, Ng MH, Mohd Isa H, Then KY, Bastion MC, Farhana A, Khursheed Alam M, Subbiah SK, Mok PL. Transplanted Erythropoietin-Expressing Mesenchymal Stem Cells Promote Pro-survival Gene Expression and Protect Photoreceptors From Sodium Iodate-Induced Cytotoxicity in a Retinal Degeneration Model. Front Cell Dev Biol. 2021 Apr 27;9:652017. doi: 10.3389/fcell.2021.652017. eCollection 2021. PMID: 33987180; PMCID: PMC8111290.
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The Prognostic Value of the Charlson's Comorbidity Index in Patients with Prolonged Acute Mechanical Ventilation: A Single Center Experience.

Tuberculosis and respiratory diseases

Song SE, Lee SH, Jo EJ, Eom JS, Mok JH, Kim MH, Kim KU, Lee MK, Lee K.
PMID: 27790281
Tuberc Respir Dis (Seoul). 2016 Oct;79(4):289-294. doi: 10.4046/trd.2016.79.4.289. Epub 2016 Oct 05.

BACKGROUND: The aim of our study was to evaluate the prognostic value of Charlson's weighted index of comorbidities (WIC) in patients with prolonged acute mechanical ventilation (PAMV, ventilator care ≥96 hours).METHODS: We retrospectively enrolled 299 Korean PAMV patients who...

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Song SE, Lee SH, Jo EJ, et al. The Prognostic Value of the Charlson's Comorbidity Index in Patients with Prolonged Acute Mechanical Ventilation: A Single Center Experience. Tuberc Respir Dis (Seoul). 2016;79(4):289-294doi: 10.4046/trd.2016.79.4.289.
Song, S. E., Lee, S. H., Jo, E. J., Eom, J. S., Mok, J. H., Kim, M. H., Kim, K. U., Lee, M. K., & Lee, K. (2016). The Prognostic Value of the Charlson's Comorbidity Index in Patients with Prolonged Acute Mechanical Ventilation: A Single Center Experience. Tuberculosis and respiratory diseases, 79(4), 289-294. https://doi.org/10.4046/trd.2016.79.4.289
Song, Seung Eon, et al. "The Prognostic Value of the Charlson's Comorbidity Index in Patients with Prolonged Acute Mechanical Ventilation: A Single Center Experience." Tuberculosis and respiratory diseases vol. 79,4 (2016): 289-294. doi: https://doi.org/10.4046/trd.2016.79.4.289
Song SE, Lee SH, Jo EJ, Eom JS, Mok JH, Kim MH, Kim KU, Lee MK, Lee K. The Prognostic Value of the Charlson's Comorbidity Index in Patients with Prolonged Acute Mechanical Ventilation: A Single Center Experience. Tuberc Respir Dis (Seoul). 2016 Oct;79(4):289-294. doi: 10.4046/trd.2016.79.4.289. Epub 2016 Oct 05. PMID: 27790281; PMCID: PMC5077733.
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Kinetics of Gene Expression Changes in Equine Fetal Interzone and Anlagen Cells Over 14 Days of Induced Chondrogenesis.

Frontiers in veterinary science

Mok CH, MacLeod JN.
PMID: 34434986
Front Vet Sci. 2021 Aug 09;8:722324. doi: 10.3389/fvets.2021.722324. eCollection 2021.

Within developing synovial joints, interzone and anlagen cells progress through divergent chondrogenic pathways to generate stable articular cartilage and transient hypertrophic anlagen cartilage, respectively. Understanding the comparative cell biology between interzone and anlagen cells may provide novel insights into...

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Mok CH, MacLeod JN. Kinetics of Gene Expression Changes in Equine Fetal Interzone and Anlagen Cells Over 14 Days of Induced Chondrogenesis. Front Vet Sci. 2021;8:722324doi: 10.3389/fvets.2021.722324.
Mok, C. H., & MacLeod, J. N. (2021). Kinetics of Gene Expression Changes in Equine Fetal Interzone and Anlagen Cells Over 14 Days of Induced Chondrogenesis. Frontiers in veterinary science, 8722324. https://doi.org/10.3389/fvets.2021.722324
Mok, Chan Hee, and MacLeod, James N. "Kinetics of Gene Expression Changes in Equine Fetal Interzone and Anlagen Cells Over 14 Days of Induced Chondrogenesis." Frontiers in veterinary science vol. 8 (2021): 722324. doi: https://doi.org/10.3389/fvets.2021.722324
Mok CH, MacLeod JN. Kinetics of Gene Expression Changes in Equine Fetal Interzone and Anlagen Cells Over 14 Days of Induced Chondrogenesis. Front Vet Sci. 2021 Aug 09;8:722324. doi: 10.3389/fvets.2021.722324. eCollection 2021. PMID: 34434986; PMCID: PMC8380811.
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Showing 1 to 12 of 134 entries