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Showing 1 to 12 of 224 entries
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Spatial sexual dimorphism of X and Y homolog gene expression in the human central nervous system during early male development.

Biology of sex differences

Johansson MM, Lundin E, Qian X, Mirzazadeh M, Halvardson J, Darj E, Feuk L, Nilsson M, Jazin E.
PMID: 26759715
Biol Sex Differ. 2016 Jan 12;7:5. doi: 10.1186/s13293-015-0056-4. eCollection 2016.

BACKGROUND: Renewed attention has been directed to the functions of the Y chromosome in the central nervous system during early human male development, due to the recent proposed involvement in neurodevelopmental diseases. PCDH11Y and NLGN4Y are of special interest...

Unusual ultra-hydrophilic, porous carbon cuboids for atmospheric-water capture.

Angewandte Chemie (International ed. in English)

Hao GP, Mondin G, Zheng Z, Biemelt T, Klosz S, Schubel R, Eychmüller A, Kaskel S.
PMID: 25522081
Angew Chem Int Ed Engl. 2015 Feb 02;54(6):1941-5. doi: 10.1002/anie.201409439. Epub 2014 Dec 17.

There is significant interest in high-performance materials that can directly and efficiently capture water vapor, particularly from air. Herein, we report a class of novel porous carbon cuboids with unusual ultra-hydrophilic properties, over which the synergistic effects between surface...

The core content of the undergraduate curriculum in Manchester.

Medical education

Mandin H, Woloschuk W.
PMID: 10532857
Med Educ. 1999 Jun;33(6):470-1. doi: 10.1046/j.1365-2923.1999.0442b.x.

No abstract available.

Cloning and characterization of the mouse Mcoln1 gene reveals an alternatively spliced transcript not seen in humans.

BMC genomics

Falardeau JL, Kennedy JC, Acierno JS, Sun M, Stahl S, Goldin E, Slaugenhaupt SA.
PMID: 11897010
BMC Genomics. 2002;3:3. doi: 10.1186/1471-2164-3-3. Epub 2002 Feb 05.

BACKGROUND: Mucolipidosis type IV (MLIV) is an autosomal recessive lysosomal storage disorder characterized by severe neurologic and ophthalmologic abnormalities. Recently the MLIV gene, MCOLN1, has been identified as a new member of the transient receptor potential (TRP) cation channel...

A schematic approach to diagnosing and resolving lecturalgia.

Medical education

McLaughlin K, Mandin H.
PMID: 11895238
Med Educ. 2001 Dec;35(12):1135-42. doi: 10.1046/j.1365-2923.2001.01090.x.

BACKGROUND: The lecture is a much used and much criticized teaching method. Lecturalgia (painful lecture) is a frequent cause of morbidity for both teachers and learners. The etiology of lecturalgia is multifactorial and multiple lecturing pathologies frequently coexist. The...

Fabry disease - current treatment and new drug development.

Current chemical genomics

Motabar O, Sidransky E, Goldin E, Zheng W.
PMID: 21127742
Curr Chem Genomics. 2010 Jul 23;4:50-6. doi: 10.2174/1875397301004010050.

Fabry disease is a rare inherited lysosomal storage disorder caused by a partial or complete deficiency of α-galactosidase A (GLA), resulting in the storage of excess cellular glycosphingolipids. Enzyme replacement therapy is available for the treatment of Fabry disease,...

Management of more severe cases of hypertension.

Canadian family physician Medecin de famille canadien

Mandin H.
PMID: 21274105
Can Fam Physician. 1985 Feb;31:329-31.

Despite the use of general guidelines for non-pharmacologic and pharmacologic therapy of hypertension, special problems do arise. In some instances the hypertension may be unresponsive or so severe that a different mode of intervention might be necessary. For such...

High-fiber rye diet increases ileal excretion of energy and macronutrients compared with low-fiber wheat diet independent of meal frequency in ileostomy subjects.

Food & nutrition research

Isaksson H, Landberg R, Sundberg B, Lundin E, Hallmans G, Zhang JX, Tidehag P, Erik Bach Knudsen K, Moazzami AA, Aman P.
PMID: 24358035
Food Nutr Res. 2013 Dec 12;57. doi: 10.3402/fnr.v57i0.18519. eCollection 2013.

BACKGROUND: Whole-grain foods and cereal dietary fiber intake is associated with lower body weight. This may partly result from lower energy utilization of high-fiber diets.OBJECTIVE: In the present study, the impact on ileal excretion of energy and macronutrients in...

Human enterovirus species B in ileocecal Crohn's disease.

Clinical and translational gastroenterology

Nyström N, Berg T, Lundin E, Skog O, Hansson I, Frisk G, Juko-Pecirep I, Nilsson M, Gyllensten U, Finkel Y, Fuxe J, Wanders A.
PMID: 23804031
Clin Transl Gastroenterol. 2013 Jun 27;4:e38. doi: 10.1038/ctg.2013.7.

OBJECTIVES: Advanced ileocecal Crohn's disease (ICD) is characterized by strictures, inflammation in the enteric nervous system (myenteric plexitis), and a high frequency of NOD2 mutations. Recent findings implicate a role of NOD2 and another CD susceptibility gene, ATG16L1, in...

Excited-state photodynamics of perylene-porphyrin dyads. 5. Tuning light-harvesting characteristics via perylene substituents, connection motif, and three-dimensional architecture.

The journal of physical chemistry. B

Kirmaier C, Song HE, Yang E, Schwartz JK, Hindin E, Diers JR, Loewe RS, Tomizaki KY, Chevalier F, Ramos L, Birge RR, Lindsey JS, Bocian DF, Holten D.
PMID: 20112987
J Phys Chem B. 2010 Nov 18;114(45):14249-64. doi: 10.1021/jp910705q. Epub 2010 Jan 29.

Seven perylene-porphyrin dyads were examined with the goal of identifying those most suitable for components of light-harvesting systems. The ideal dyad should exhibit strong absorption by the perylene in the green, undergo rapid and efficient excited-state energy transfer from...

High throughput screening for inhibitors of alpha-galactosidase.

Current chemical genomics

Motabar O, Liu K, Southall N, Marugan JJ, Goldin E, Sidransky E, Zheng W.
PMID: 21331308
Curr Chem Genomics. 2010 Dec 03;4:67-73. doi: 10.2174/1875397301004010067.

Fabry disease is a rare X-linked lysosomal storage disorder caused by a deficiency in α-galactosidase A (GLA), which catalyzes the hydrolysis of terminal α-galactosyl groups from glycosphingolipids, such as globotriaosylceramide (Gb3). Many of the mutations in the GLA gene...

Fast solubilization of recalcitrant cellulosic biomass by the basidiomycete fungus Laetisaria arvalis involves successive secretion of oxidative and hydrolytic enzymes.

Biotechnology for biofuels

Navarro D, Rosso MN, Haon M, Olivé C, Bonnin E, Lesage-Meessen L, Chevret D, Coutinho PM, Henrissat B, Berrin JG.
PMID: 25320637
Biotechnol Biofuels. 2014 Oct 08;7(1):143. doi: 10.1186/s13068-014-0143-5. eCollection 2014.

BACKGROUND: Enzymatic breakdown of lignocellulosic biomass is a known bottleneck for the production of high-value molecules and biofuels from renewable sources. Filamentous fungi are the predominant natural source of enzymes acting on lignocellulose. We describe the extraordinary cellulose-deconstructing capacity...

Showing 1 to 12 of 224 entries