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Rigosertib elicits potent anti-tumor responses in colorectal cancer by inhibiting Ras signaling pathway.

Cellular signalling

Rahmani F, Hashemzehi M, Avan A, Barneh F, Asgharzadeh F, Moradi Marjaneh R, Soleimani A, Parizadeh M, Ferns GA, Ghayour Mobarhan M, Ryzhikov M, Afshari AR, Ahmadian MR, Giovannetti E, Jafari M, Khazaei M, Hassanian SM.
PMID: 34214591
Cell Signal. 2021 Sep;85:110069. doi: 10.1016/j.cellsig.2021.110069. Epub 2021 Jun 29.

BACKGROUND: The therapeutic potency of Rigosertib (RGS) in the treatment of the myelodysplastic syndrome has been investigated previously, but little is known about its mechanisms of action.METHODS: The present study integrates systems and molecular biology approaches to investigate the...

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Rahmani F, Hashemzehi M, Avan A, et al. Rigosertib elicits potent anti-tumor responses in colorectal cancer by inhibiting Ras signaling pathway. Cell Signal. 2021;85:110069doi: 10.1016/j.cellsig.2021.110069.
Rahmani, F., Hashemzehi, M., Avan, A., Barneh, F., Asgharzadeh, F., Moradi Marjaneh, R., Soleimani, A., Parizadeh, M., Ferns, G. A., Ghayour Mobarhan, M., Ryzhikov, M., Afshari, A. R., Ahmadian, M. R., Giovannetti, E., Jafari, M., Khazaei, M., & Hassanian, S. M. (2021). Rigosertib elicits potent anti-tumor responses in colorectal cancer by inhibiting Ras signaling pathway. Cellular signalling, 85110069. https://doi.org/10.1016/j.cellsig.2021.110069
Rahmani, Farzad, et al. "Rigosertib elicits potent anti-tumor responses in colorectal cancer by inhibiting Ras signaling pathway." Cellular signalling vol. 85 (2021): 110069. doi: https://doi.org/10.1016/j.cellsig.2021.110069
Rahmani F, Hashemzehi M, Avan A, Barneh F, Asgharzadeh F, Moradi Marjaneh R, Soleimani A, Parizadeh M, Ferns GA, Ghayour Mobarhan M, Ryzhikov M, Afshari AR, Ahmadian MR, Giovannetti E, Jafari M, Khazaei M, Hassanian SM. Rigosertib elicits potent anti-tumor responses in colorectal cancer by inhibiting Ras signaling pathway. Cell Signal. 2021 Sep;85:110069. doi: 10.1016/j.cellsig.2021.110069. Epub 2021 Jun 29. PMID: 34214591.
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Effects of Securigera securidaca Extract on Lipolysis and Adipogenesis in Diabetic Rats.

Cholesterol

Ghorbani A, Moradi Marjaneh R, Rajaei Z, Hadjzadeh MA.
PMID: 25161769
Cholesterol. 2014;2014:582106. doi: 10.1155/2014/582106. Epub 2014 Aug 03.

Diabetes mellitus is associated with dysregulation of adipose tissue metabolism and increased level of serum lipids. In our previous work we found that Securigera securidaca decreases cholesterol level in blood of diabetic rats. The present study was carried out...

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Ghorbani A, Moradi Marjaneh R, Rajaei Z, et al. Effects of Securigera securidaca Extract on Lipolysis and Adipogenesis in Diabetic Rats. Cholesterol. 2014;2014:582106doi: 10.1155/2014/582106.
Ghorbani, A., Moradi Marjaneh, R., Rajaei, Z., & Hadjzadeh, M. A. (2014). Effects of Securigera securidaca Extract on Lipolysis and Adipogenesis in Diabetic Rats. Cholesterol, 2014582106. https://doi.org/10.1155/2014/582106
Ghorbani, Ahmad, et al. "Effects of Securigera securidaca Extract on Lipolysis and Adipogenesis in Diabetic Rats." Cholesterol vol. 2014 (2014): 582106. doi: https://doi.org/10.1155/2014/582106
Ghorbani A, Moradi Marjaneh R, Rajaei Z, Hadjzadeh MA. Effects of Securigera securidaca Extract on Lipolysis and Adipogenesis in Diabetic Rats. Cholesterol. 2014;2014:582106. doi: 10.1155/2014/582106. Epub 2014 Aug 03. PMID: 25161769; PMCID: PMC4137550.
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Rigosertib elicits potent anti-tumor responses in colorectal cancer by inhibiting Ras signaling pathway.

Cellular signalling

Rahmani F, Hashemzehi M, Avan A, Barneh F, Asgharzadeh F, Moradi Marjaneh R, Soleimani A, Parizadeh M, Ferns GA, Ghayour Mobarhan M, Ryzhikov M, Afshari AR, Ahmadian MR, Giovannetti E, Jafari M, Khazaei M, Hassanian SM.
PMID: 34214591
Cell Signal. 2021 Sep;85:110069. doi: 10.1016/j.cellsig.2021.110069. Epub 2021 Jun 29.

BACKGROUND: The therapeutic potency of Rigosertib (RGS) in the treatment of the myelodysplastic syndrome has been investigated previously, but little is known about its mechanisms of action.METHODS: The present study integrates systems and molecular biology approaches to investigate the...

Cite
Rahmani F, Hashemzehi M, Avan A, et al. Rigosertib elicits potent anti-tumor responses in colorectal cancer by inhibiting Ras signaling pathway. Cell Signal. 2021;85:110069doi: 10.1016/j.cellsig.2021.110069.
Rahmani, F., Hashemzehi, M., Avan, A., Barneh, F., Asgharzadeh, F., Moradi Marjaneh, R., Soleimani, A., Parizadeh, M., Ferns, G. A., Ghayour Mobarhan, M., Ryzhikov, M., Afshari, A. R., Ahmadian, M. R., Giovannetti, E., Jafari, M., Khazaei, M., & Hassanian, S. M. (2021). Rigosertib elicits potent anti-tumor responses in colorectal cancer by inhibiting Ras signaling pathway. Cellular signalling, 85110069. https://doi.org/10.1016/j.cellsig.2021.110069
Rahmani, Farzad, et al. "Rigosertib elicits potent anti-tumor responses in colorectal cancer by inhibiting Ras signaling pathway." Cellular signalling vol. 85 (2021): 110069. doi: https://doi.org/10.1016/j.cellsig.2021.110069
Rahmani F, Hashemzehi M, Avan A, Barneh F, Asgharzadeh F, Moradi Marjaneh R, Soleimani A, Parizadeh M, Ferns GA, Ghayour Mobarhan M, Ryzhikov M, Afshari AR, Ahmadian MR, Giovannetti E, Jafari M, Khazaei M, Hassanian SM. Rigosertib elicits potent anti-tumor responses in colorectal cancer by inhibiting Ras signaling pathway. Cell Signal. 2021 Sep;85:110069. doi: 10.1016/j.cellsig.2021.110069. Epub 2021 Jun 29. PMID: 34214591.
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Diabetes and COVID-19; a Review of Possible Mechanisms.

Current pharmaceutical design

Moradi-Marjaneh R, Asgharzadeh F, Khordad E, Marjaneh MM.
PMID: 33655850
Curr Pharm Des. 2021;27(21):2522-2527. doi: 10.2174/1381612827666210303141846.

Coronavirus disease 2019 (SARS-CoV-2) (COVID-19) has recently raised worldwide public health concerns. The available data on COVID-19 in patients with diabetes is limited but generally indicate that there is an increased risk of developing COVID-19 infection in diabetic patients,...

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Moradi-Marjaneh R, Asgharzadeh F, Khordad E, et al. Diabetes and COVID-19; a Review of Possible Mechanisms. Curr Pharm Des. 2021;27(21):2522-2527doi: 10.2174/1381612827666210303141846.
Moradi-Marjaneh, R., Asgharzadeh, F., Khordad, E., & Marjaneh, M. M. (2021). Diabetes and COVID-19; a Review of Possible Mechanisms. Current pharmaceutical design, 27(21), 2522-2527. https://doi.org/10.2174/1381612827666210303141846
Moradi-Marjaneh, Reyhaneh, et al. "Diabetes and COVID-19; a Review of Possible Mechanisms." Current pharmaceutical design vol. 27,21 (2021): 2522-2527. doi: https://doi.org/10.2174/1381612827666210303141846
Moradi-Marjaneh R, Asgharzadeh F, Khordad E, Marjaneh MM. Diabetes and COVID-19; a Review of Possible Mechanisms. Curr Pharm Des. 2021;27(21):2522-2527. doi: 10.2174/1381612827666210303141846. PMID: 33655850.
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The hepatoprotective effects of fennel seeds extract and .

Food science & nutrition

Samadi-Noshahr Z, Hadjzadeh MA, Moradi-Marjaneh R, Khajavi-Rad A.
PMID: 33598196
Food Sci Nutr. 2020 Dec 30;9(2):1121-1131. doi: 10.1002/fsn3.2090. eCollection 2021 Feb.

Hypoglycemic, anti-inflammatory, and antioxidant activities of fennel have been recorded in numerous investigations. The study aimed to evaluate the protective effects of fennel or its active component

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Samadi-Noshahr Z, Hadjzadeh MA, Moradi-Marjaneh R, et al. The hepatoprotective effects of fennel seeds extract and . Food Sci Nutr. 2020;9(2):1121-1131doi: 10.1002/fsn3.2090.
Samadi-Noshahr, Z., Hadjzadeh, M. A., Moradi-Marjaneh, R., & Khajavi-Rad, A. (2021). The hepatoprotective effects of fennel seeds extract and . Food science & nutrition, 9(2), 1121-1131. https://doi.org/10.1002/fsn3.2090
Samadi-Noshahr, Zahra, et al. "The hepatoprotective effects of fennel seeds extract and ." Food science & nutrition vol. 9,2 (2021): 1121-1131. doi: https://doi.org/10.1002/fsn3.2090
Samadi-Noshahr Z, Hadjzadeh MA, Moradi-Marjaneh R, Khajavi-Rad A. The hepatoprotective effects of fennel seeds extract and . Food Sci Nutr. 2020 Dec 30;9(2):1121-1131. doi: 10.1002/fsn3.2090. eCollection 2021 Feb. PMID: 33598196; PMCID: PMC7866591.
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Mass transfer in the Frenkel-Kontorova chain initiated by molecule impact.

Physical review. E

Moradi Marjaneh A, Saadatmand D, Evazzade I, Babicheva RI, Soboleva EG, Srikanth N, Zhou K, Korznikova EA, Dmitriev SV.
PMID: 30253582
Phys Rev E. 2018 Aug;98(2):023003. doi: 10.1103/PhysRevE.98.023003.

The Frenkel-Kontorova chain with a free end is used to study initiation and propagation of crowdions (antikinks) caused by impact of a molecule consisting of K atoms. It is found that molecules with 1

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Moradi Marjaneh A, Saadatmand D, Evazzade I, et al. Mass transfer in the Frenkel-Kontorova chain initiated by molecule impact. Phys Rev E. 2018;98(2):023003doi: 10.1103/PhysRevE.98.023003.
Moradi Marjaneh, A., Saadatmand, D., Evazzade, I., Babicheva, R. I., Soboleva, E. G., Srikanth, N., Zhou, K., Korznikova, E. A., & Dmitriev, S. V. (2018). Mass transfer in the Frenkel-Kontorova chain initiated by molecule impact. Physical review. E, 98(2), 023003. https://doi.org/10.1103/PhysRevE.98.023003
Moradi Marjaneh, A, et al. "Mass transfer in the Frenkel-Kontorova chain initiated by molecule impact." Physical review. E vol. 98,2 (2018): 023003. doi: https://doi.org/10.1103/PhysRevE.98.023003
Moradi Marjaneh A, Saadatmand D, Evazzade I, Babicheva RI, Soboleva EG, Srikanth N, Zhou K, Korznikova EA, Dmitriev SV. Mass transfer in the Frenkel-Kontorova chain initiated by molecule impact. Phys Rev E. 2018 Aug;98(2):023003. doi: 10.1103/PhysRevE.98.023003. PMID: 30253582.
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Angiotensin receptor blocker Losartan inhibits tumor growth of colorectal cancer.

EXCLI journal

Hashemzehi M, Rahmani F, Khoshakhlagh M, Avan A, Asgharzadeh F, Barneh F, Moradi-Marjaneh R, Soleimani A, Fiuji H, Ferns GA, Ryzhikov M, Jafari M, Khazaei M, Hassanian SM.
PMID: 33883980
EXCLI J. 2021 Mar 01;20:506-521. doi: 10.17179/excli2020-3083. eCollection 2021.

The renin-angiotensin system (RAS) is up-regulated in patients with colorectal cancer (CRC) and is reported to be associated with poor prognosis and chemo-resistance. Here we explored the therapeutic potential of targeting RAS in CRC using Losartan, an angiotensin receptor...

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Hashemzehi M, Rahmani F, Khoshakhlagh M, et al. Angiotensin receptor blocker Losartan inhibits tumor growth of colorectal cancer. EXCLI J. 2021;20:506-521doi: 10.17179/excli2020-3083.
Hashemzehi, M., Rahmani, F., Khoshakhlagh, M., Avan, A., Asgharzadeh, F., Barneh, F., Moradi-Marjaneh, R., Soleimani, A., Fiuji, H., Ferns, G. A., Ryzhikov, M., Jafari, M., Khazaei, M., & Hassanian, S. M. (2021). Angiotensin receptor blocker Losartan inhibits tumor growth of colorectal cancer. EXCLI journal, 20506-521. https://doi.org/10.17179/excli2020-3083
Hashemzehi, Milad, et al. "Angiotensin receptor blocker Losartan inhibits tumor growth of colorectal cancer." EXCLI journal vol. 20 (2021): 506-521. doi: https://doi.org/10.17179/excli2020-3083
Hashemzehi M, Rahmani F, Khoshakhlagh M, Avan A, Asgharzadeh F, Barneh F, Moradi-Marjaneh R, Soleimani A, Fiuji H, Ferns GA, Ryzhikov M, Jafari M, Khazaei M, Hassanian SM. Angiotensin receptor blocker Losartan inhibits tumor growth of colorectal cancer. EXCLI J. 2021 Mar 01;20:506-521. doi: 10.17179/excli2020-3083. eCollection 2021. PMID: 33883980; PMCID: PMC8056058.
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Showing 1 to 7 of 7 entries