Clinical ophthalmology (Auckland, N.Z.)

Maruyama Y, Ikeda Y, Mori K, Ueno M, Yoshikawa H, Kinoshita S.
PMID: 26300624
Clin Ophthalmol. 2015 Aug 07;9:1429-36. doi: 10.2147/OPTH.S87613. eCollection 2015.

BACKGROUND: The purpose of this study was to prospectively evaluate and compare intraocular pressure (IOP) reduction efficacy and safety between bimatoprost and latanoprost-timolol fixed combination (LTFC) in Japanese patients with open-angle glaucoma.METHODS: In this prospective, randomized, non-masked study, after...

Vaccines

Nakagami H, Koriyama H, Morishita R.
PMID: 26344893
Vaccines (Basel). 2014 Nov 26;2(4):832-40. doi: 10.3390/vaccines2040832.

Vaccines are commonly used as a preventive medicine for infectious diseases worldwide; however, the trial for an amyloid beta vaccine against Alzheimer's disease will open a new concept in vaccination. In case of therapeutic vaccines for cancer, their targets...

Journal of clinical biochemistry and nutrition

Nakajima N, Kozu K, Kobayashi S, Nishiyama R, Okubo R, Akai Y, Moriyama M, Kinukawa N.
PMID: 27499580
J Clin Biochem Nutr. 2016 Jul;59(1):53-7. doi: 10.3164/jcbn.16-11. Epub 2016 May 21.

Overexpression of IGF-1R has been demonstrated in gastrointestinal cancers, and its expression is reported as the result of the loss of tumor suppressors. IL-16 is involved in the pathophysiological process of chronic inflammatory diseases. The aim of this study...

Nature communications

Matsuo S, Takeshita S, Tanaka T, Nakaharai S, Tsukagoshi K, Moriyama T, Ono T, Kobayashi K.
PMID: 26337445
Nat Commun. 2015 Sep 04;6:8066. doi: 10.1038/ncomms9066.

Massless Dirac electron systems such as graphene exhibit a distinct half-integer quantum Hall effect, and in the bipolar transport regime co-propagating edge states along the p-n junction are realized. Additionally, these edge states are uniformly mixed at the junction,...

JMIR medical informatics

Puspitasari I, Moriyama K, Fukui K, Numao M.
PMID: 25783222
JMIR Med Inform. 2015 Mar 17;3(1):e16. doi: 10.2196/medinform.3803.

BACKGROUND: Non-medical professionals (consumers) are increasingly using the Internet to support their health information needs. However, the cognitive effort required to perform health information searches is affected by the consumer's familiarity with health topics. Consumers may have different levels...

Oncology letters

Hashimoto I, Nagata T, Sekine S, Moriyama M, Shibuya K, Hojo S, Matsui K, Yoshioka I, Okumura T, Hori T, Shimada Y, Tsukada K.
PMID: 28356964
Oncol Lett. 2017 Feb;13(2):819-826. doi: 10.3892/ol.2016.5499. Epub 2016 Dec 14.

To understand the roles of pluripotent stem cell-inducing genes in gastric cancer, the expression of Krüppel-like factor 4 (KLF4), Nanog, octamer-binding transcription factor 4 (Oct4), avian myelocytomatosis viral oncogene homolog (c-Myc) and sex-determining region Y-box 2 (SOX2) was examined...

Oncology letters

Sasaki H, Maekawa M, Tatematsu T, Okuda K, Moriyama S, Yano M, Fujii Y.
PMID: 25621040
Oncol Lett. 2015 Feb;9(2):709-712. doi: 10.3892/ol.2014.2719. Epub 2014 Nov 20.

Point mutation of the

Oncotarget

Kanda T, Yasui S, Nakamura M, Nakamoto S, Takahashi K, Wu S, Sasaki R, Haga Y, Ogasawara S, Saito T, Kobayashi K, Kiyono S, Ooka Y, Suzuki E, Chiba T, Maruyama H, Imazeki F, Moriyama M, Kato N.
PMID: 29545925
Oncotarget. 2018 Feb 03;9(14):11631-11637. doi: 10.18632/oncotarget.24391. eCollection 2018 Feb 20.

BACKGROUND: Interferon-free treatment can achieve higher sustained virological response (SVR) rates, even in patients in whom hepatitis C virus (HCV) could not be eradicated in the interferon treatment era. Immune restoration in the liver is occasionally associated with HCV...

Organic letters

Toda Y, Gomyou S, Tanaka S, Komiyama Y, Kikuchi A, Suga H.
PMID: 29039956
Org Lett. 2017 Nov 03;19(21):5786-5789. doi: 10.1021/acs.orglett.7b02722.

Preparation of a range of oxazolidinones, including enantioenriched N-aryl-substituted oxazolidinones, in which tetraarylphosphonium salts (TAPS) catalyze the [3 + 2] coupling reaction of isocyanates and epoxides effectively, is described. The key finding is a Brønsted acid/halide ion bifunctional catalyst...

Chemistry, an Asian journal

Kawamata M, Sugai T, Minoura M, Maruyama Y, Furukawa K, Holstrom C, Nemykin VN, Nakano H, Matano Y.
PMID: 28181737
Chem Asian J. 2017 Apr 04;12(7):816-821. doi: 10.1002/asia.201700204. Epub 2017 Feb 28.

NH-bridged and pyrazine-fused metallodiazaporphyrin dimers have been prepared from nickel(II) and copper(II) complexes of 3-amino-5,15-diazaporphyrin by Pd-catalyzed C-N cross-coupling and oxidative dimerization reactions, respectively. The synergistic effects of the nitrogen bridges and meso-nitrogen atoms play major roles in enhancing...

Plastic and reconstructive surgery. Global open

Okochi M, Okochi H, Sakaba T, Momiyama M, Ueda K.
PMID: 28607852
Plast Reconstr Surg Glob Open. 2017 May 16;5(5):e1324. doi: 10.1097/GOX.0000000000001324. eCollection 2017 May.

We performed hepatic artery (HA) reconstruction on 24 patients between January 2010 and October 2016. Six of 24 patients used an Ikuta type A-II vascular clamp (A-II group). The mean age was 38.0 years (range, 1-61 years). There was...

Gland surgery

Kijima Y, Koriyama C, Fujii T, Hirokaga K, Ishigure K, Kaneko T, Kayano S, Miyamoto S, Sagara Y, Sakurai T, Sakurai T, Sotome K, Ueo H, Wakita K, Watatani M.
PMID: 26005649
Gland Surg. 2015 Apr;4(2):179-94. doi: 10.3978/j.issn.2227-684X.2015.01.06.

BACKGROUND: Immediate volume replacement using a free dermal fat graft (FDFG) has been proven safe with early postoperative benefits. The aims of the present study were to clarify adequate indications and risk factors associated with operative morbidity.PATIENTS AND METHODS:...