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Showing 1 to 12 of 61 entries
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Role of ooplasmic segregation in mammalian development.

Roux's archives of developmental biology : the official organ of the EDBO

Evsikov SV, Morozova LM, Solomko AP.
PMID: 28305883
Rouxs Arch Dev Biol. 1994 Jan;203(4):199-204. doi: 10.1007/BF00636335.

A new micromanipulation technique permitted the scrambling of the zygote cytoplasm. Such interference had no effect on preimplantation development, and when zygotes with scrambled cytoplasm were transfered to the pseudopregnant females, normal and fertile mice were born. This demonstrates...

SMARTS (Systematic Monitoring of Adverse events Related to TreatmentS): The development of a pragmatic patient-completed checklist to assess antipsychotic drug side effects.

Therapeutic advances in psychopharmacology

Haddad PM, Fleischhacker WW, Peuskens J, Cavallaro R, Lean ME, Morozova M, Reynolds G, Azorin JM, Thomas P, Möller HJ.
PMID: 24490026
Ther Adv Psychopharmacol. 2014 Feb;4(1):15-21. doi: 10.1177/2045125313510195.

OBJECTIVES: Antipsychotic drug side effects are common and can cause stigmatisation, decreased quality of life, poor adherence, and secondary morbidity and mortality. Systematic assessment of anticipated side effects is recommended as part of good clinical care, but is uncommon...

Drug Delivery From Polymer-Based Nanopharmaceuticals-An Experimental Study Complemented by Simulations of Selected Diffusion Processes.

Frontiers in bioengineering and biotechnology

Macha IJ, Ben-Nissan B, Vilchevskaya EN, Morozova AS, Abali BE, Müller WH, Rickert W.
PMID: 30906737
Front Bioeng Biotechnol. 2019 Mar 08;7:37. doi: 10.3389/fbioe.2019.00037. eCollection 2019.

The success of medical therapy depends on the correct amount and the appropriate delivery of the required drugs for treatment. By using biodegradable polymers a drug delivery over a time span of weeks or even months is made possible....

Sulfoxides, Analogues of L-Methionine and L-Cysteine As Pro-Drugs against Gram-Positive and Gram-Negative Bacteria.

Acta naturae

Anufrieva NV, Morozova EA, Kulikova VV, Bazhulina NP, Manukhov IV, Degtev DI, Gnuchikh EY, Rodionov AN, Zavilgelsky GB, Demidkina TV.
PMID: 26798500
Acta Naturae. 2015 Oct-Dec;7(4):128-35.

The problem of resistance to antibiotics requires the development of new classes of broad-spectrum antimicrobial drugs. The concept of pro-drugs allows researchers to look for new approaches to obtain effective drugs with improved pharmacokinetic and pharmacodynamic properties. Thiosulfinates, formed...

Immune checkpoints bone marrow expression as the predictor of clinical outcome in myelodysplastic syndrome.

Leukemia research reports

Tcvetkov N, Gusak A, Morozova E, Moiseev I, Baykov V, Barabanshikova M, Lepik K, Bakin E, Vlasova J, Osipova A, Zubarovskaya L, Afanasyev B.
PMID: 32695574
Leuk Res Rep. 2020 Jun 28;14:100215. doi: 10.1016/j.lrr.2020.100215. eCollection 2020.

AIMS: In our single-center retrospective study we evaluated whether level of different checkpoint molecules in bone marrow biopsies at diagnosis affect the clinical course of patients with myelodysplastic syndrome (MDS).METHODS AND RESULTS: A consecutive cohort of 55 MDS patients...

Benzophenone-3 promotion of mammary tumorigenesis is diet-dependent.

Oncotarget

Kariagina A, Morozova E, Hoshyar R, Aupperlee MD, Borin MA, Haslam SZ, Schwartz RC.
PMID: 33400736
Oncotarget. 2020 Dec 01;11(48):4465-4478. doi: 10.18632/oncotarget.27831. eCollection 2020 Dec 01.

Benzophenone-3 is a putative endocrine disrupting chemical and common ingredient in sunscreens. The potential of endocrine disrupting chemicals to act as agonists or antagonists in critical hormonally regulated processes, such as mammary gland development and mammary tumorigenesis, demands evaluation...

Kinetic and pharmacokinetic characteristics of therapeutic methinoninе γ-lyase encapsulated in polyion complex vesicles.

Biochimie

Kulikova VV, Morozova EA, Anufrieva NV, Koval VS, Lyfenko AD, Lesnova EI, Kushch AA, Revtovich SV, Demidkina TV.
PMID: 34923045
Biochimie. 2021 Dec 16;194:13-18. doi: 10.1016/j.biochi.2021.12.004. Epub 2021 Dec 16.

Therapeutic enzymes used for the treatment of a wide range of human disorders often suffer from suboptimal pharmacokinetics and stability. Engineering approaches such as encapsulation in micro- and nanocarriers, and replacements of amino acid residues of the native enzyme...

Towards a representative reference for MRI-based human axon radius assessment using light microscopy.

NeuroImage

Mordhorst L, Morozova M, Papazoglou S, Fricke B, Oeschger JM, Tabarin T, Rusch H, Jäger C, Geyer S, Weiskopf N, Morawski M, Mohammadi S.
PMID: 35032659
Neuroimage. 2022 Jan 12;118906. doi: 10.1016/j.neuroimage.2022.118906. Epub 2022 Jan 12.

Non-invasive assessment of axon radii via MRI bears great potential for clinical and neuroscience research as it is a main determinant of the neuronal conduction velocity. However, there is a lack of representative histological reference data at the scale...

Ionic Polyureas-A Novel Subclass of Poly(Ionic Liquid)s for CO.

Membranes

Morozova SM, Lozinskaya EI, Sardon H, Suárez-García F, Vlasov PS, Vaudemont R, Vygodskii YS, Shaplov AS.
PMID: 32961905
Membranes (Basel). 2020 Sep 18;10(9). doi: 10.3390/membranes10090240.

The growing concern for climate change and global warming has given rise to investigations in various research fields, including one particular area dedicated to the creation of solid sorbents for efficient CO

Copy Number Variation of Satellite III (1q12) in Patients With Schizophrenia.

Frontiers in genetics

Ershova ES, Agafonova ON, Zakharova NV, Bravve LV, Jestkova EM, Golimbet VE, Lezheiko TV, Morozova AY, Martynov AV, Veiko RV, Umriukhin PE, Kostyuk GP, Kutsev SI, Veiko NN, Kostyuk SV.
PMID: 31850056
Front Genet. 2019 Nov 22;10:1132. doi: 10.3389/fgene.2019.01132. eCollection 2019.

No abstract available.

Clathrin-Mediated Endocytosis Delivers Proteolytically Active Phytaspases Into Plant Cells.

Frontiers in plant science

Trusova SV, Teplova AD, Golyshev SA, Galiullina RA, Morozova EA, Chichkova NV, Vartapetian AB.
PMID: 31379892
Front Plant Sci. 2019 Jul 18;10:873. doi: 10.3389/fpls.2019.00873. eCollection 2019.

Phytaspases belong to the family of plant subtilisin-like proteases and are distinct from other family members, as they have strict and rarely occurring aspartate cleavage specificity and unusual localization dynamics. After being secreted into the apoplast of healthy plant...

The Comparison of a New Ultrasound-Induced Depression Model to the Chronic Mild Stress Paradigm.

Frontiers in behavioral neuroscience

Zorkina YA, Zubkov EA, Morozova AY, Ushakova VM, Chekhonin VP.
PMID: 31312126
Front Behav Neurosci. 2019 Jul 02;13:146. doi: 10.3389/fnbeh.2019.00146. eCollection 2019.

Willner's "chronic mild stress" (CMS) model is a globally recognized and most commonly used depression model. A depression model induced by ultrasonic exposure of variable frequencies has been created in our laboratory. This article compares two models of the...

Showing 1 to 12 of 61 entries