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Showing 1 to 12 of 46 entries
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Correction: Blindness and Glaucoma: A Multicenter Data Review from 7 Academic Eye Clinics.

PloS one

Rossetti L, Digiuni M, Montesano G, Centofanti M, Fea AM, Iester M, Frezzotti P, Figus M, Ferreras A, Oddone F, Tanga L, Rolle T, Battaglino V, Posarelli C, Motolese I, Mittica P, Bagaglia SA, Menicacci C, De Cilla' S, Autelitano A, Fogagnolo P.
PMID: 26934677
PLoS One. 2016 Mar 02;11(3):e0151010. doi: 10.1371/journal.pone.0151010. eCollection 2016.

No abstract available.

Antidepressant activity of fingolimod in mice.

Pharmacology research & perspectives

di Nuzzo L, Orlando R, Tognoli C, Di Pietro P, Bertini G, Miele J, Bucci D, Motolese M, Scaccianoce S, Caruso A, Mauro G, De Lucia C, Battaglia G, Bruno V, Fabene PF, Nicoletti F.
PMID: 26171219
Pharmacol Res Perspect. 2015 Jun;3(3):e00135. doi: 10.1002/prp2.135. Epub 2015 May 24.

Recent findings indicate that fingolimod, the first oral drug approved for the treatment of multiple sclerosis (MS), acts as a direct inhibitor of histone deacetylases (HDACs) and enhances the production of brain-derived neurotrophic factor (BDNF) in the CNS. Both...

Effects of the Calcium Antagonist Felodipine on Resting and Stress Testing Blood Pressure in Essential Hypertension.

American journal of therapeutics

Cardillo C, Mores N, Campia U, Musumeci V, Motolese M, Folli G.
PMID: 11835087
Am J Ther. 1994 Oct;1(3):198-205. doi: 10.1097/00045391-199410000-00005.

The current study analyzed the effects of different doses of the calcium channel blocker felodipine on cardiovascular response to a set of standardized laboratory tasks. We randomly allocated 21 essential hypertensive patients to receive extended release felodipine 5 mg,...

Functional expression of a single-chain antibody to ErbB-2 in plants and cell-free systems.

Journal of translational medicine

Galeffi P, Lombardi A, Pietraforte I, Novelli F, Di Donato M, Sperandei M, Tornambé A, Fraioli R, Martayan A, Natali PG, Benevolo M, Mottolese M, Ylera F, Cantale C, Giacomini P.
PMID: 17010186
J Transl Med. 2006 Sep 29;4:39. doi: 10.1186/1479-5876-4-39.

BACKGROUND: Aberrant signaling by ErbB-2 (HER 2, Neu), a member of the human Epidermal Growth Factor (EGF) receptor family, is associated with an aggressive clinical behaviour of carcinomas, particularly breast tumors. Antibodies targeting the ErbB-2 pathway are a preferred...

Dual targeting of HER3 and MEK may overcome HER3-dependent drug-resistance of colon cancers.

Oncotarget

Bon G, Loria R, Amoreo CA, Verdina A, Sperduti I, Mastrofrancesco A, Soddu S, Diodoro MG, Mottolese M, Todaro M, Stassi G, Milella M, De Maria R, Falcioni R.
PMID: 29312543
Oncotarget. 2016 Aug 19;8(65):108463-108479. doi: 10.18632/oncotarget.11400. eCollection 2017 Dec 12.

Although the medical treatment of colorectal cancer has evolved greatly in the last years, a significant portion of early-stage patients develops recurrence after therapies. The current clinical trials are directed to evaluate new drug combinations and treatment schedules. By...

Neoplastic Implications in Patients Suffering from Hidradenitis Suppurativa under Systemic Treatments.

Biomedicines

Li Pomi F, Macca L, Motolese A, Ingrasciotta Y, Berretta M, Guarneri C.
PMID: 34829823
Biomedicines. 2021 Nov 01;9(11). doi: 10.3390/biomedicines9111594.

Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory skin disease of the apocrine glands. It typically involves the axillary, submammary, genital, inguinal, perineal, and perianal regions. The development of abscesses, sinus tracts, and scars can lead to pain, scarring,...

Immunogenicity and safety of mRNA COVID-19 vaccines in people with multiple sclerosis treated with different disease-modifying therapies.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Capone F, Lucchini M, Ferraro E, Bianco A, Rossi M, Cicia A, Cortese A, Cruciani A, De Arcangelis V, De Giglio L, Motolese F, Sancetta B, Mirabella M, Di Lazzaro V.
PMID: 34859382
Neurotherapeutics. 2021 Dec 03; doi: 10.1007/s13311-021-01165-9. Epub 2021 Dec 03.

The potential impact of disease-modifying therapies (DMTs) for multiple sclerosis (MS) on COVID-19 vaccination is poorly understood. According to recent observations, the humoral immune response could be impaired in patients treated with ocrelizumab or fingolimod. Our study evaluated the...

Beyond the skin involvement in Darier disease: A complicated neuropsychiatric phenotype.

Clinical case reports

Li Pomi F, Motolese A, Bertino L, Macca L, Arminio NC, Cardia R, Vaccaro M, Borgia F.
PMID: 34194784
Clin Case Rep. 2021 Jun 23;9(6):e04263. doi: 10.1002/ccr3.4263. eCollection 2021 Jun.

Psichiatric illness such as depression, schizophrenia and cognitive deficiency are frequently associated with the Darier Disease. Physicians should be aware of such association to allow prompt diagnosis and early interventions of potentially life-threatening psychiatric disorders.

Ulcerative necrobiosis lipoidica: case report of an atypical presentation and literature review.

European review for medical and pharmacological sciences

Di Bartolomeo L, Macca L, Motolese A, Guarneri C, Guarneri F.
PMID: 34661264
Eur Rev Med Pharmacol Sci. 2021 Oct;25(19):6047-6050. doi: 10.26355/eurrev_202110_26882.

Necrobiosis lipoidica (NL) is a rare chronic granulomatous degenerative skin disease by unknown causes, which is mostly associated with diabetes mellitus, usually presenting with typical plaques of the shins. Although less common, some ulcerative forms may be seen in...

Metronidazole Encephalopathy EEG Features: A Case Report with Systematic Review of the Literature.

Brain sciences

Ricci L, Motolese F, Tombini M, Lanzone J, Rea R, Di Matteo F, Di Lazzaro V, Assenza G.
PMID: 32290116
Brain Sci. 2020 Apr 10;10(4). doi: 10.3390/brainsci10040227.

Metronidazole-induced encephalopathy (MIE) is a rare and often under-recognized iatrogenic condition. The diagnosis should be considered in metronidazole-treated patients presenting with acute encephalopathy, unprovoked seizures and cerebellar signs. While typical magnetic resonance imaging (MRI) findings strongly support the diagnosis,...

New tools for shaping plasticity to enhance recovery after stroke.

Handbook of clinical neurology

Motolese F, Capone F, Di Lazzaro V.
PMID: 35034743
Handb Clin Neurol. 2022;184:299-315. doi: 10.1016/B978-0-12-819410-2.00016-3.

Stroke is the second most common cause of death worldwide and its prevalence is projected to increase in the coming years in parallel with the increase of life expectancy. Despite the great improvements in the management of the acute...

A 48-week update of a multicentre real-life experience of dupilumab in adult patients with moderate-to-severe atopic dermatitis.

The Journal of dermatological treatment

Fargnoli MC, Esposito M, Ferrucci S, Girolomoni G, Offidani A, Patrizi A, Peris K, Costanzo A, Malara G, Pellacani G, Romanelli M, Amerio P, Cristaudo A, Flori ML, Motolese A, Betto P, Patruno C, Pigatto P, Peccianti C, Stinco G, Zalaudek I, Bianchi L, Boccaletti V, Cannavo SP, Cusano F, Lembo S, Mozzillo R, Gallo R, Potenza C, Rongioletti F, Tiberio R, Grieco T, Micali G, Persechino S, Pettinato M, Pucci S, Stingeni L, Caruso C, Argenziano G.
PMID: 32436765
J Dermatolog Treat. 2020 Jul 03;1-4. doi: 10.1080/09546634.2020.1773379. Epub 2020 Jul 03.

No abstract available.

Showing 1 to 12 of 46 entries