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Characterization of the mechanical properties of resected porcine organ tissue using optical fiber photoelastic polarimetry.

Biomedical optics express

Hudnut AW, Babaei B, Liu S, Larson BK, Mumenthaler SM, Armani AM.
PMID: 29082093
Biomed Opt Express. 2017 Sep 25;8(10):4663-4670. doi: 10.1364/BOE.8.004663. eCollection 2017 Oct 01.

Characterizing the mechanical behavior of living tissue presents an interesting challenge because the elasticity varies by eight orders of magnitude, from 50Pa to 5GPa. In the present work, a non-destructive optical fiber photoelastic polarimetry system is used to analyze...

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Hudnut AW, Babaei B, Liu S, et al. Characterization of the mechanical properties of resected porcine organ tissue using optical fiber photoelastic polarimetry. Biomed Opt Express. 2017;8(10):4663-4670doi: 10.1364/BOE.8.004663.
Hudnut, A. W., Babaei, B., Liu, S., Larson, B. K., Mumenthaler, S. M., & Armani, A. M. (2017). Characterization of the mechanical properties of resected porcine organ tissue using optical fiber photoelastic polarimetry. Biomedical optics express, 8(10), 4663-4670. https://doi.org/10.1364/BOE.8.004663
Hudnut, Alexa W, et al. "Characterization of the mechanical properties of resected porcine organ tissue using optical fiber photoelastic polarimetry." Biomedical optics express vol. 8,10 (2017): 4663-4670. doi: https://doi.org/10.1364/BOE.8.004663
Hudnut AW, Babaei B, Liu S, Larson BK, Mumenthaler SM, Armani AM. Characterization of the mechanical properties of resected porcine organ tissue using optical fiber photoelastic polarimetry. Biomed Opt Express. 2017 Sep 25;8(10):4663-4670. doi: 10.1364/BOE.8.004663. eCollection 2017 Oct 01. PMID: 29082093; PMCID: PMC5654808.
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Linezolid for treatment of catheter-related cerebrospinal fluid infections in preterm infants.

BMJ case reports

Langgartner M, Mutenthaler A, Haiden N, Pollak A, Berger A.
PMID: 21686411
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.11.2008.1217. Epub 2009 May 08.

Ventriculostomy-related cerebrospinal fluid (CSF) infection remains a major problem in neonatal intensive care. The spectrum of pathogens causing these infections is dominated by coagulase-negative staphylococci, and vancomycin is the antibiotic of choice for treatment. However, vancomycin is known to...

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Langgartner M, Mutenthaler A, Haiden N, et al. Linezolid for treatment of catheter-related cerebrospinal fluid infections in preterm infants. BMJ Case Rep. 2009;2009doi: 10.1136/bcr.11.2008.1217.
Langgartner, M., Mutenthaler, A., Haiden, N., Pollak, A., & Berger, A. (2009). Linezolid for treatment of catheter-related cerebrospinal fluid infections in preterm infants. BMJ case reports, 2009. https://doi.org/10.1136/bcr.11.2008.1217
Langgartner, M, et al. "Linezolid for treatment of catheter-related cerebrospinal fluid infections in preterm infants." BMJ case reports vol. 2009 (2009). doi: https://doi.org/10.1136/bcr.11.2008.1217
Langgartner M, Mutenthaler A, Haiden N, Pollak A, Berger A. Linezolid for treatment of catheter-related cerebrospinal fluid infections in preterm infants. BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.11.2008.1217. Epub 2009 May 08. PMID: 21686411; PMCID: PMC3028023.
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Cancer as a moving target: understanding the composition and rebound growth kinetics of recurrent tumors.

Evolutionary applications

Foo J, Leder K, Mumenthaler SM.
PMID: 23396647
Evol Appl. 2013 Jan;6(1):54-69. doi: 10.1111/eva.12019. Epub 2012 Nov 16.

We introduce a stochastic branching process model of diversity in recurrent tumors whose growth is driven by drug resistance. Here, an initially declining population can escape certain extinction via the production of mutants whose fitness is drawn at random...

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Foo J, Leder K, Mumenthaler SM. Cancer as a moving target: understanding the composition and rebound growth kinetics of recurrent tumors. Evol Appl. 2012;6(1):54-69doi: 10.1111/eva.12019.
Foo, J., Leder, K., & Mumenthaler, S. M. (2013). Cancer as a moving target: understanding the composition and rebound growth kinetics of recurrent tumors. Evolutionary applications, 6(1), 54-69. https://doi.org/10.1111/eva.12019
Foo, Jasmine, et al. "Cancer as a moving target: understanding the composition and rebound growth kinetics of recurrent tumors." Evolutionary applications vol. 6,1 (2013): 54-69. doi: https://doi.org/10.1111/eva.12019
Foo J, Leder K, Mumenthaler SM. Cancer as a moving target: understanding the composition and rebound growth kinetics of recurrent tumors. Evol Appl. 2013 Jan;6(1):54-69. doi: 10.1111/eva.12019. Epub 2012 Nov 16. PMID: 23396647; PMCID: PMC3567471.
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The Need for Integrative Computational Oncology: An Illustrated Example through MMP-Mediated Tissue Degradation.

Frontiers in oncology

Mumenthaler SM, D'Antonio G, Preziosi L, Macklin P.
PMID: 23898463
Front Oncol. 2013 Jul 26;3:194. doi: 10.3389/fonc.2013.00194. eCollection 2013.

PHYSICAL ONCOLOGY IS A GROWING FORCE IN CANCER RESEARCH, AND IT IS ENHANCED BY INTEGRATIVE COMPUTATIONAL ONCOLOGY: the fusion of novel experiments with mathematical and computational modeling. Computational models must be assessed with accurate numerical methods on correctly scaled...

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Mumenthaler SM, D'Antonio G, Preziosi L, et al. The Need for Integrative Computational Oncology: An Illustrated Example through MMP-Mediated Tissue Degradation. Front Oncol. 2013;3:194doi: 10.3389/fonc.2013.00194.
Mumenthaler, S. M., D'Antonio, G., Preziosi, L., & Macklin, P. (2013). The Need for Integrative Computational Oncology: An Illustrated Example through MMP-Mediated Tissue Degradation. Frontiers in oncology, 3194. https://doi.org/10.3389/fonc.2013.00194
Mumenthaler, Shannon M, et al. "The Need for Integrative Computational Oncology: An Illustrated Example through MMP-Mediated Tissue Degradation." Frontiers in oncology vol. 3 (2013): 194. doi: https://doi.org/10.3389/fonc.2013.00194
Mumenthaler SM, D'Antonio G, Preziosi L, Macklin P. The Need for Integrative Computational Oncology: An Illustrated Example through MMP-Mediated Tissue Degradation. Front Oncol. 2013 Jul 26;3:194. doi: 10.3389/fonc.2013.00194. eCollection 2013. PMID: 23898463; PMCID: PMC3724164.
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Oxytocin-like signaling in ants influences metabolic gene expression and locomotor activity.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Liutkevičiūtė Z, Gil-Mansilla E, Eder T, Casillas-Pérez B, Di Giglio MG, Muratspahić E, Grebien F, Rattei T, Muttenthaler M, Cremer S, Gruber CW.
PMID: 29939785
FASEB J. 2018 Jun 25;fj201800443. doi: 10.1096/fj.201800443. Epub 2018 Jun 25.

Ants are emerging model systems to study cellular signaling because distinct castes possess different physiologic phenotypes within the same colony. Here we studied the functionality of inotocin signaling, an insect ortholog of mammalian oxytocin (OT), which was recently discovered...

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Liutkevičiūtė Z, Gil-Mansilla E, Eder T, et al. Oxytocin-like signaling in ants influences metabolic gene expression and locomotor activity. FASEB J. 2018;fj201800443doi: 10.1096/fj.201800443.
Liutkevičiūtė, Z., Gil-Mansilla, E., Eder, T., Casillas-Pérez, B., Di Giglio, M. G., Muratspahić, E., Grebien, F., Rattei, T., Muttenthaler, M., Cremer, S., & Gruber, C. W. (2018). Oxytocin-like signaling in ants influences metabolic gene expression and locomotor activity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, fj201800443. https://doi.org/10.1096/fj.201800443
Liutkevičiūtė, Zita, et al. "Oxytocin-like signaling in ants influences metabolic gene expression and locomotor activity." FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol. (2018): fj201800443. doi: https://doi.org/10.1096/fj.201800443
Liutkevičiūtė Z, Gil-Mansilla E, Eder T, Casillas-Pérez B, Di Giglio MG, Muratspahić E, Grebien F, Rattei T, Muttenthaler M, Cremer S, Gruber CW. Oxytocin-like signaling in ants influences metabolic gene expression and locomotor activity. FASEB J. 2018 Jun 25;fj201800443. doi: 10.1096/fj.201800443. Epub 2018 Jun 25. PMID: 29939785; PMCID: PMC6174076.
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The Evaluation Of Iron Deficiency And Iron Overload.

Deutsches Arzteblatt international

Gattermann N, Muckenthaler M, Kulozik AE, Metzgeroth G, Hastka J.
PMID: 34755596
Dtsch Arztebl Int. 2021 Dec 10; doi: 10.3238/arztebl.m2021.0290. Epub 2021 Dec 10.

BACKGROUND: In the western world, 2-5% of women of child-bearing age suffer from irondeficiency anemia. Iron overload due to chronic treatment with blood transfusions or hereditary hemochromatosis is much rarer.METHODS: This review is based on pertinent publications retrieved by...

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Gattermann N, Muckenthaler M, Kulozik AE, et al. The Evaluation Of Iron Deficiency And Iron Overload. Dtsch Arztebl Int. 2021;doi: 10.3238/arztebl.m2021.0290.
Gattermann, N., Muckenthaler, M., Kulozik, A. E., Metzgeroth, G., & Hastka, J. (2021). The Evaluation Of Iron Deficiency And Iron Overload. Deutsches Arzteblatt international, . https://doi.org/10.3238/arztebl.m2021.0290
Gattermann, Norbert, et al. "The Evaluation Of Iron Deficiency And Iron Overload." Deutsches Arzteblatt international vol. (2021). doi: https://doi.org/10.3238/arztebl.m2021.0290
Gattermann N, Muckenthaler M, Kulozik AE, Metzgeroth G, Hastka J. The Evaluation Of Iron Deficiency And Iron Overload. Dtsch Arztebl Int. 2021 Dec 10; doi: 10.3238/arztebl.m2021.0290. Epub 2021 Dec 10. PMID: 34755596.
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Elucidating tumor-stromal metabolic crosstalk in colorectal cancer through integration of constraint-based models and LC-MS metabolomics.

Metabolic engineering

Wang J, Delfarah A, Gelbach PE, Fong E, Macklin P, Mumenthaler SM, Graham NA, Finley SD.
PMID: 34838998
Metab Eng. 2021 Nov 25;69:175-187. doi: 10.1016/j.ymben.2021.11.006. Epub 2021 Nov 25.

Colorectal cancer (CRC) is a major cause of morbidity and mortality in the United States. Tumor-stromal metabolic crosstalk in the tumor microenvironment promotes CRC development and progression, but exactly how stromal cells, in particular cancer-associated fibroblasts (CAFs), affect the...

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Wang J, Delfarah A, Gelbach PE, et al. Elucidating tumor-stromal metabolic crosstalk in colorectal cancer through integration of constraint-based models and LC-MS metabolomics. Metab Eng. 2021;69:175-187doi: 10.1016/j.ymben.2021.11.006.
Wang, J., Delfarah, A., Gelbach, P. E., Fong, E., Macklin, P., Mumenthaler, S. M., Graham, N. A., & Finley, S. D. (2021). Elucidating tumor-stromal metabolic crosstalk in colorectal cancer through integration of constraint-based models and LC-MS metabolomics. Metabolic engineering, 69175-187. https://doi.org/10.1016/j.ymben.2021.11.006
Wang, Junmin, et al. "Elucidating tumor-stromal metabolic crosstalk in colorectal cancer through integration of constraint-based models and LC-MS metabolomics." Metabolic engineering vol. 69 (2021): 175-187. doi: https://doi.org/10.1016/j.ymben.2021.11.006
Wang J, Delfarah A, Gelbach PE, Fong E, Macklin P, Mumenthaler SM, Graham NA, Finley SD. Elucidating tumor-stromal metabolic crosstalk in colorectal cancer through integration of constraint-based models and LC-MS metabolomics. Metab Eng. 2021 Nov 25;69:175-187. doi: 10.1016/j.ymben.2021.11.006. Epub 2021 Nov 25. PMID: 34838998.
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Reprogramming CBX8-PRC1 function with a positive allosteric modulator.

Cell chemical biology

Suh JL, Bsteh D, Hart B, Si Y, Weaver TM, Pribitzer C, Lau R, Soni S, Ogana H, Rectenwald JM, Norris JL, Cholensky SH, Sagum C, Umana JD, Li D, Hardy B, Bedford MT, Mumenthaler SM, Lenz HJ, Kim YM, Wang GG, Pearce KH, James LI, Kireev DB, Musselman CA, Frye SV, Bell O.
PMID: 34715055
Cell Chem Biol. 2021 Oct 26; doi: 10.1016/j.chembiol.2021.10.003. Epub 2021 Oct 26.

Canonical targeting of Polycomb repressive complex 1 (PRC1) to repress developmental genes is mediated by cell-type-specific, paralogous chromobox (CBX) proteins (CBX2, 4, 6, 7, and 8). Based on their central role in silencing and their dysregulation associated with human...

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Suh JL, Bsteh D, Hart B, et al. Reprogramming CBX8-PRC1 function with a positive allosteric modulator. Cell Chem Biol. 2021;doi: 10.1016/j.chembiol.2021.10.003.
Suh, J. L., Bsteh, D., Hart, B., Si, Y., Weaver, T. M., Pribitzer, C., Lau, R., Soni, S., Ogana, H., Rectenwald, J. M., Norris, J. L., Cholensky, S. H., Sagum, C., Umana, J. D., Li, D., Hardy, B., Bedford, M. T., Mumenthaler, S. M., Lenz, H. J., Kim, Y. M., Wang, G. G., Pearce, K. H., James, L. I., Kireev, D. B., Musselman, C. A., Frye, S. V., & Bell, O. (2021). Reprogramming CBX8-PRC1 function with a positive allosteric modulator. Cell chemical biology, . https://doi.org/10.1016/j.chembiol.2021.10.003
Suh, Junghyun L, et al. "Reprogramming CBX8-PRC1 function with a positive allosteric modulator." Cell chemical biology vol. (2021). doi: https://doi.org/10.1016/j.chembiol.2021.10.003
Suh JL, Bsteh D, Hart B, Si Y, Weaver TM, Pribitzer C, Lau R, Soni S, Ogana H, Rectenwald JM, Norris JL, Cholensky SH, Sagum C, Umana JD, Li D, Hardy B, Bedford MT, Mumenthaler SM, Lenz HJ, Kim YM, Wang GG, Pearce KH, James LI, Kireev DB, Musselman CA, Frye SV, Bell O. Reprogramming CBX8-PRC1 function with a positive allosteric modulator. Cell Chem Biol. 2021 Oct 26; doi: 10.1016/j.chembiol.2021.10.003. Epub 2021 Oct 26. PMID: 34715055.
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Heterodimeric Insecticidal Peptide Provides New Insights into the Molecular and Functional Diversity of Ant Venoms.

ACS pharmacology & translational science

Touchard A, Mendel HC, Boulogne I, Herzig V, Braga Emidio N, King GF, Triquigneaux M, Jaquillard L, Beroud R, De Waard M, Delalande O, Dejean A, Muttenthaler M, Duplais C.
PMID: 33344898
ACS Pharmacol Transl Sci. 2020 Oct 06;3(6):1211-1224. doi: 10.1021/acsptsci.0c00119. eCollection 2020 Dec 11.

Ants use venom for predation, defense, and communication; however, the molecular diversity, function, and potential applications of ant venom remains understudied compared to other venomous lineages such as arachnids, snakes and cone snails. In this work, we used a...

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Touchard A, Mendel HC, Boulogne I, et al. Heterodimeric Insecticidal Peptide Provides New Insights into the Molecular and Functional Diversity of Ant Venoms. ACS Pharmacol Transl Sci. 2020;3(6):1211-1224doi: 10.1021/acsptsci.0c00119.
Touchard, A., Mendel, H. C., Boulogne, I., Herzig, V., Braga Emidio, N., King, G. F., Triquigneaux, M., Jaquillard, L., Beroud, R., De Waard, M., Delalande, O., Dejean, A., Muttenthaler, M., & Duplais, C. (2020). Heterodimeric Insecticidal Peptide Provides New Insights into the Molecular and Functional Diversity of Ant Venoms. ACS pharmacology & translational science, 3(6), 1211-1224. https://doi.org/10.1021/acsptsci.0c00119
Touchard, Axel, et al. "Heterodimeric Insecticidal Peptide Provides New Insights into the Molecular and Functional Diversity of Ant Venoms." ACS pharmacology & translational science vol. 3,6 (2020): 1211-1224. doi: https://doi.org/10.1021/acsptsci.0c00119
Touchard A, Mendel HC, Boulogne I, Herzig V, Braga Emidio N, King GF, Triquigneaux M, Jaquillard L, Beroud R, De Waard M, Delalande O, Dejean A, Muttenthaler M, Duplais C. Heterodimeric Insecticidal Peptide Provides New Insights into the Molecular and Functional Diversity of Ant Venoms. ACS Pharmacol Transl Sci. 2020 Oct 06;3(6):1211-1224. doi: 10.1021/acsptsci.0c00119. eCollection 2020 Dec 11. PMID: 33344898; PMCID: PMC7737211.
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EHA Research Roadmap on Hemoglobinopathies and Thalassemia: An Update.

HemaSphere

Iolascon A, De Franceschi L, Muckenthaler M, Taher A, Rees D, de Montalembert M, Rivella S, Eleftheriou A, Cappellini MD.
PMID: 31723835
Hemasphere. 2019 Jun 04;3(3):e208. doi: 10.1097/HS9.0000000000000208. eCollection 2019 Jun.

The inherited disorders of hemoglobin, which include sickle cell disease and thalassemias, are the most common and widespread distributed monogenic disorders. Due to a selective advantage in malaria regions, these hemoglobin defects are particularly frequent in Africa, Asia, or...

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Iolascon A, De Franceschi L, Muckenthaler M, et al. EHA Research Roadmap on Hemoglobinopathies and Thalassemia: An Update. Hemasphere. 2019;3(3):e208doi: 10.1097/HS9.0000000000000208.
Iolascon, A., De Franceschi, L., Muckenthaler, M., Taher, A., Rees, D., de Montalembert, M., Rivella, S., Eleftheriou, A., & Cappellini, M. D. (2019). EHA Research Roadmap on Hemoglobinopathies and Thalassemia: An Update. HemaSphere, 3(3), e208. https://doi.org/10.1097/HS9.0000000000000208
Iolascon, Achille, et al. "EHA Research Roadmap on Hemoglobinopathies and Thalassemia: An Update." HemaSphere vol. 3,3 (2019): e208. doi: https://doi.org/10.1097/HS9.0000000000000208
Iolascon A, De Franceschi L, Muckenthaler M, Taher A, Rees D, de Montalembert M, Rivella S, Eleftheriou A, Cappellini MD. EHA Research Roadmap on Hemoglobinopathies and Thalassemia: An Update. Hemasphere. 2019 Jun 04;3(3):e208. doi: 10.1097/HS9.0000000000000208. eCollection 2019 Jun. PMID: 31723835; PMCID: PMC6746021.
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[Facial pain and neuralgias. Diagnosis and treatment.].

Schmerz (Berlin, Germany)

Mumenthaler M.
PMID: 18415360
Schmerz. 1989 Jun;3(2):59-66. doi: 10.1007/BF02527480.

The first type of facial pain is of vascular origin. Cluster headache is described as well as its subgroups and carotidodynia. Two organic lesions of the arterial wall can also cause facial pain: dissection of the internal carotid artery...

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Mumenthaler M. Gesichtsneuralgien und Gesichtsschmerzen Diagnostik und Therapie. [Facial pain and neuralgias. Diagnosis and treatment.]. Schmerz. 1989;3(2):59-66doi: 10.1007/BF02527480.
Mumenthaler, M. (1989). Gesichtsneuralgien und Gesichtsschmerzen Diagnostik und Therapie. [Facial pain and neuralgias. Diagnosis and treatment.]. Schmerz (Berlin, Germany), 3(2), 59-66. https://doi.org/10.1007/BF02527480
Mumenthaler, M. "Gesichtsneuralgien und Gesichtsschmerzen Diagnostik und Therapie." [Facial pain and neuralgias. Diagnosis and treatment.]. Schmerz (Berlin, Germany) vol. 3,2 (1989): 59-66. doi: https://doi.org/10.1007/BF02527480
Mumenthaler M. Gesichtsneuralgien und Gesichtsschmerzen Diagnostik und Therapie. [Facial pain and neuralgias. Diagnosis and treatment.]. Schmerz. 1989 Jun;3(2):59-66. doi: 10.1007/BF02527480. German. PMID: 18415360.
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VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer.

Molecular oncology

Ghate NB, Kim S, Spiller E, Kim S, Shin Y, Rhie SK, Smbatyan G, Lenz HJ, Mumenthaler SM, An W.
PMID: 34312968
Mol Oncol. 2021 Oct;15(10):2801-2817. doi: 10.1002/1878-0261.13068. Epub 2021 Aug 08.

Histone modification is aberrantly regulated in cancer and generates an unbalanced state of gene transcription. VprBP, a recently identified kinase, phosphorylates histone H2A on threonine 120 (T120) and is involved in oncogenic transcriptional dysregulation; however, its specific role in...

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Ghate NB, Kim S, Spiller E, et al. VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer. Mol Oncol. 2021;15(10):2801-2817doi: 10.1002/1878-0261.13068.
Ghate, N. B., Kim, S., Spiller, E., Kim, S., Shin, Y., Rhie, S. K., Smbatyan, G., Lenz, H. J., Mumenthaler, S. M., & An, W. (2021). VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer. Molecular oncology, 15(10), 2801-2817. https://doi.org/10.1002/1878-0261.13068
Ghate, Nikhil Baban, et al. "VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer." Molecular oncology vol. 15,10 (2021): 2801-2817. doi: https://doi.org/10.1002/1878-0261.13068
Ghate NB, Kim S, Spiller E, Kim S, Shin Y, Rhie SK, Smbatyan G, Lenz HJ, Mumenthaler SM, An W. VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer. Mol Oncol. 2021 Oct;15(10):2801-2817. doi: 10.1002/1878-0261.13068. Epub 2021 Aug 08. PMID: 34312968; PMCID: PMC8486565.
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Showing 1 to 12 of 57 entries