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Showing 1 to 12 of 380 entries
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ERRα regulates the growth of triple-negative breast cancer cells via S6K1-dependent mechanism.

Signal transduction and targeted therapy

Berman AY, Manna S, Schwartz NS, Katz YE, Sun Y, Behrmann CA, Yu JJ, Plas DR, Alayev A, Holz MK.
PMID: 28890840
Signal Transduct Target Ther. 2017;2. doi: 10.1038/sigtrans.2017.35. Epub 2017 Aug 25.

Estrogen-related receptor alpha (ERRα) is an orphan nuclear factor that is a master regulator of cellular energy metabolism. ERRα is overexpressed in a variety of tumors, including ovarian, prostate, colorectal, cervical and breast, and is associated with a more...

Seamustard (Undaria pinnatifida) Improves Growth, Immunity, Fatty Acid Profile and Reduces Cholesterol in Hanwoo Steers.

Asian-Australasian journal of animal sciences

Hwang JA, Islam MM, Ahmed ST, Mun HS, Kim GM, Kim YJ, Yang CJ.
PMID: 25083105
Asian-Australas J Anim Sci. 2014 Aug;27(8):1114-23. doi: 10.5713/ajas.2014.14072.

The study was designed to evaluate the effect of 2% seamustard (Undaria pinnatifida) by-product (SW) on growth performance, immunity, carcass characteristics, cholesterol content and fatty acid profile in Hanwoo steers. A total of 20 Hanwoo steers (ave. 22 months...

Immunotherapeutic intervention with oncolytic adenovirus in mouse mammary tumors.

Oncoimmunology

Gibson H, Munns S, Freytag S, Barton K, Veenstra J, Bettahi I, Bissonette J, Wei WZ.
PMID: 25949865
Oncoimmunology. 2015 Feb 03;4(1):e984523. doi: 10.4161/2162402X.2014.984523. eCollection 2015 Jan.

The goal is to elucidate the immune modulating activity of an adenovirus (Adv) vector which showed therapeutic activity in human clinical trials. The oncolytic adenovirus (Adv/CD-TK) expressing two suicide genes was tested in two HER2/neu positive BALB/c mouse mammary...

Analysis of Prescribing Patterns of Atypical Antipsychotics in Lhu Caserta.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Farina G, Menditto E, Manna S, Pagliaro C, Troncone C, Putignano D, Orlando V, Linguiti C, Buffardi GF, Tari MG.
PMID: 27201311
Value Health. 2014 Nov;17(7):A464-5. doi: 10.1016/j.jval.2014.08.1297. Epub 2014 Oct 26.

No abstract available.

Radical trideuteromethylation with deuterated dimethyl sulfoxide in the synthesis of heterocycles and labelled building blocks.

Chemical communications (Cambridge, England)

Caporaso R, Manna S, Zinken S, Kochnev AR, Lukyanenko ER, Kurkin AV, Antonchick AP.
PMID: 27711354
Chem Commun (Camb). 2016 Oct 13;52(84):12486-12489. doi: 10.1039/c6cc07196a.

The potential of deuterated pharmaceuticals is being widely demonstrated. Here we describe the first trideuteromethylation under radical reaction conditions using deuterated dimethyl sulfoxide as a reagent for the synthesis of labelled heterocycles and trideuteromethylated compounds. A broad scope of...

Hyper-accumulation of starch and oil in a Chlamydomonas mutant affected in a plant-specific DYRK kinase.

Biotechnology for biofuels

Schulz-Raffelt M, Chochois V, Auroy P, Cuiné S, Billon E, Dauvillée D, Li-Beisson Y, Peltier G.
PMID: 26958078
Biotechnol Biofuels. 2016 Mar 08;9:55. doi: 10.1186/s13068-016-0469-2. eCollection 2016.

BACKGROUND: Because of their high biomass productivity and their ability to accumulate high levels of energy-rich reserve compounds such as oils or starch, microalgae represent a promising feedstock for the production of biofuel. Accumulation of reserve compounds takes place...

Tamoxifen Action in ER-Negative Breast Cancer.

Signal transduction insights

Manna S, Holz MK.
PMID: 26989346
Sign Transduct Insights. 2016 Feb 10;5:1-7. doi: 10.4137/STI.S29901.

Breast cancer is a highly heterogeneous disease. Tamoxifen is a selective estrogen receptor (ER) modulator and is mainly indicated for the treatment of breast cancer in postmenopausal women and postsurgery neoadjuvant therapy in ER-positive breast cancers. Interestingly, 5-10% of...

Copper(I)-Catalyzed Radical Addition of Acetophenones to Alkynes in Furan Synthesis.

Organic letters

Manna S, Antonchick AP.
PMID: 26277912
Org Lett. 2015 Sep 04;17(17):4300-3. doi: 10.1021/acs.orglett.5b02114. Epub 2015 Aug 17.

A synthesis of multisubstituted furans from readily available acetophenones and electron-deficient alkynes via direct C(sp(3))-H bond functionalization under radical reaction conditions is described. The developed transformation is catalyzed by copper(I) salts using di-tert-butyl peroxide as an external oxidant. This...

Corrigendum to 'Live birth derived from oocyte spindle transfer to prevent mitochondrial disease' [Reproductive BioMedicine Online 34 (2017) 361-368].

Reproductive biomedicine online

Zhang JJ, Liu H, Luo S, Lu Z, Chávez-Badiola A, Liu Z, Yang M, Merhi Z, Silber SJ, Munné S, Konstantinidis M, Wells D, Huang T.
PMID: 28495440
Reprod Biomed Online. 2017 Jul;35(1):49. doi: 10.1016/j.rbmo.2017.04.002. Epub 2017 May 08.

No abstract available.

Copper resistance of Calluna vulgaris originating from the pollution gradient of a Cu-Ni smelter, in southwest Finland.

Environmental pollution (Barking, Essex : 1987)

Monni S, Salemaa M, White C, Tuittila E, Huopalainen M.
PMID: 15092892
Environ Pollut. 2000 Aug;109(2):211-9. doi: 10.1016/s0269-7491(99)00265-1.

The copper (Cu) resistance of 1-year-old seedlings of heather (Calluna vulgaris) was tested in a greenhouse experiment. The plant material originated from seeds collected from three peatland sites located 1.2 km to the NW, and 2.5 and 5.5 km...

Facilitation of problem finding among first year medical school students undergoing problem-based learning.

Teaching and learning in medicine

Yoshioka T, Suganuma T, Tang AC, Matsushita S, Manno S, Kozu T.
PMID: 15833723
Teach Learn Med. 2005;17(2):136-41. doi: 10.1207/s15328015tlm1702_7.

BACKGROUND: Adaptation to problem-based learning (PBL) is a difficult process for high school graduates who are not used to self-directed learning, especially in the freshmen year of medical school. The difficulty includes finding problems from a given case.PURPOSE: Evaluate...

Protective role of fish oil (Maxepa) on early events of rat mammary carcinogenesis by modulation of DNA-protein crosslinks, cell proliferation and p53 expression.

Cancer cell international

Manna S, Chakraborty T, Damodaran S, Samanta K, Rana B, Chatterjee M.
PMID: 17470299
Cancer Cell Int. 2007 May 01;7:6. doi: 10.1186/1475-2867-7-6.

BACKGROUND: Fish oil is known to protect from many types of cancers of the colon, liver, breast, prostate and lung 123. The objective of the present study was to evaluate the role of fish oil [Maxepa, supplemented at a...

Showing 1 to 12 of 380 entries