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Different Statistical Approaches to Characterization of Adipocyte Size in Offspring of Obese Rats: Effects of Maternal or Offspring Exercise Intervention.

Frontiers in physiology

Ibáñez CA, Vázquez-Martínez M, León-Contreras JC, Reyes-Castro LA, Rodríguez-González GL, Bautista CJ, Nathanielsz PW, Zambrano E.
PMID: 30524294
Front Physiol. 2018 Nov 15;9:1571. doi: 10.3389/fphys.2018.01571. eCollection 2018.

Adipocyte size (AS) shows asymmetric distribution related to current metabolic state, e.g., adipogenesis or lipolysis. We profiled AS distribution using different statistical approaches in offspring (F1) of control (C) and obese (MO) mothers (F0) with and without F0 or...

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Ibáñez CA, Vázquez-Martínez M, León-Contreras JC, et al. Different Statistical Approaches to Characterization of Adipocyte Size in Offspring of Obese Rats: Effects of Maternal or Offspring Exercise Intervention. Front Physiol. 2018;9:1571doi: 10.3389/fphys.2018.01571.
Ibáñez, C. A., Vázquez-Martínez, M., León-Contreras, J. C., Reyes-Castro, L. A., Rodríguez-González, G. L., Bautista, C. J., Nathanielsz, P. W., & Zambrano, E. (2018). Different Statistical Approaches to Characterization of Adipocyte Size in Offspring of Obese Rats: Effects of Maternal or Offspring Exercise Intervention. Frontiers in physiology, 91571. https://doi.org/10.3389/fphys.2018.01571
Ibáñez, Carlos A, et al. "Different Statistical Approaches to Characterization of Adipocyte Size in Offspring of Obese Rats: Effects of Maternal or Offspring Exercise Intervention." Frontiers in physiology vol. 9 (2018): 1571. doi: https://doi.org/10.3389/fphys.2018.01571
Ibáñez CA, Vázquez-Martínez M, León-Contreras JC, Reyes-Castro LA, Rodríguez-González GL, Bautista CJ, Nathanielsz PW, Zambrano E. Different Statistical Approaches to Characterization of Adipocyte Size in Offspring of Obese Rats: Effects of Maternal or Offspring Exercise Intervention. Front Physiol. 2018 Nov 15;9:1571. doi: 10.3389/fphys.2018.01571. eCollection 2018. PMID: 30524294; PMCID: PMC6262415.
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Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance.

Nature communications

Chen YT, Yang QY, Hu Y, Liu XD, de Avila JM, Zhu MJ, Nathanielsz PW, Du M.
PMID: 34824246
Nat Commun. 2021 Nov 25;12(1):6845. doi: 10.1038/s41467-021-27171-1.

Maternal obesity (MO) predisposes offspring to obesity and metabolic disorders but little is known about the contribution of offspring brown adipose tissue (BAT). We find that MO impairs fetal BAT development, which persistently suppresses BAT thermogenesis and primes female...

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Chen YT, Yang QY, Hu Y, et al. Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance. Nat Commun. 2021;12(1):6845doi: 10.1038/s41467-021-27171-1.
Chen, Y. T., Yang, Q. Y., Hu, Y., Liu, X. D., de Avila, J. M., Zhu, M. J., Nathanielsz, P. W., & Du, M. (2021). Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance. Nature communications, 12(1), 6845. https://doi.org/10.1038/s41467-021-27171-1
Chen, Yan-Ting, et al. "Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance." Nature communications vol. 12,1 (2021): 6845. doi: https://doi.org/10.1038/s41467-021-27171-1
Chen YT, Yang QY, Hu Y, Liu XD, de Avila JM, Zhu MJ, Nathanielsz PW, Du M. Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance. Nat Commun. 2021 Nov 25;12(1):6845. doi: 10.1038/s41467-021-27171-1. PMID: 34824246; PMCID: PMC8617289.
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Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance.

Nature communications

Chen YT, Yang QY, Hu Y, Liu XD, de Avila JM, Zhu MJ, Nathanielsz PW, Du M.
PMID: 34824246
Nat Commun. 2021 Nov 25;12(1):6845. doi: 10.1038/s41467-021-27171-1.

Maternal obesity (MO) predisposes offspring to obesity and metabolic disorders but little is known about the contribution of offspring brown adipose tissue (BAT). We find that MO impairs fetal BAT development, which persistently suppresses BAT thermogenesis and primes female...

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Chen YT, Yang QY, Hu Y, et al. Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance. Nat Commun. 2021;12(1):6845doi: 10.1038/s41467-021-27171-1.
Chen, Y. T., Yang, Q. Y., Hu, Y., Liu, X. D., de Avila, J. M., Zhu, M. J., Nathanielsz, P. W., & Du, M. (2021). Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance. Nature communications, 12(1), 6845. https://doi.org/10.1038/s41467-021-27171-1
Chen, Yan-Ting, et al. "Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance." Nature communications vol. 12,1 (2021): 6845. doi: https://doi.org/10.1038/s41467-021-27171-1
Chen YT, Yang QY, Hu Y, Liu XD, de Avila JM, Zhu MJ, Nathanielsz PW, Du M. Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance. Nat Commun. 2021 Nov 25;12(1):6845. doi: 10.1038/s41467-021-27171-1. PMID: 34824246; PMCID: PMC8617289.
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Evaluating Functional Immunity Following Encapsulated Bacterial Infection and Vaccination.

Vaccines

Toh ZQ, Higgins RA, Mazarakis N, Abbott E, Nathanielsz J, Balloch A, Mulholland K, Licciardi PV.
PMID: 34203030
Vaccines (Basel). 2021 Jun 20;9(6). doi: 10.3390/vaccines9060677.

Encapsulated bacteria such as

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Toh ZQ, Higgins RA, Mazarakis N, et al. Evaluating Functional Immunity Following Encapsulated Bacterial Infection and Vaccination. Vaccines (Basel). 2021;9(6)doi: 10.3390/vaccines9060677.
Toh, Z. Q., Higgins, R. A., Mazarakis, N., Abbott, E., Nathanielsz, J., Balloch, A., Mulholland, K., & Licciardi, P. V. (2021). Evaluating Functional Immunity Following Encapsulated Bacterial Infection and Vaccination. Vaccines, 9(6), . https://doi.org/10.3390/vaccines9060677
Toh, Zheng Quan, et al. "Evaluating Functional Immunity Following Encapsulated Bacterial Infection and Vaccination." Vaccines vol. 9,6 (2021). doi: https://doi.org/10.3390/vaccines9060677
Toh ZQ, Higgins RA, Mazarakis N, Abbott E, Nathanielsz J, Balloch A, Mulholland K, Licciardi PV. Evaluating Functional Immunity Following Encapsulated Bacterial Infection and Vaccination. Vaccines (Basel). 2021 Jun 20;9(6). doi: 10.3390/vaccines9060677. PMID: 34203030; PMCID: PMC8234458.
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DHA Supplementation of Obese Rats throughout Pregnancy and Lactation Modifies Milk Composition and Anxiety Behavior of Offspring.

Nutrients

Zambrano E, Rodríguez-González GL, Reyes-Castro LA, Bautista CJ, Castro-Rodríguez DC, Juárez-Pilares G, Ibáñez CA, Hernández-Rojas A, Nathanielsz PW, Montaño S, Arredondo A, Huang F, Bolaños-Jiménez F.
PMID: 34959795
Nutrients. 2021 Nov 26;13(12). doi: 10.3390/nu13124243.

We investigated if supplementing obese mothers (MO) with docosahexaenoic acid (DHA) improves milk long-chain polyunsaturated fatty acid (LCPUFA) composition and offspring anxiety behavior. From weaning throughout pregnancy and lactation, female Wistar rats ate chow (C) or a high-fat diet...

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Zambrano E, Rodríguez-González GL, Reyes-Castro LA, et al. DHA Supplementation of Obese Rats throughout Pregnancy and Lactation Modifies Milk Composition and Anxiety Behavior of Offspring. Nutrients. 2021;13(12)doi: 10.3390/nu13124243.
Zambrano, E., Rodríguez-González, G. L., Reyes-Castro, L. A., Bautista, C. J., Castro-Rodríguez, D. C., Juárez-Pilares, G., Ibáñez, C. A., Hernández-Rojas, A., Nathanielsz, P. W., Montaño, S., Arredondo, A., Huang, F., & Bolaños-Jiménez, F. (2021). DHA Supplementation of Obese Rats throughout Pregnancy and Lactation Modifies Milk Composition and Anxiety Behavior of Offspring. Nutrients, 13(12), . https://doi.org/10.3390/nu13124243
Zambrano, Elena, et al. "DHA Supplementation of Obese Rats throughout Pregnancy and Lactation Modifies Milk Composition and Anxiety Behavior of Offspring." Nutrients vol. 13,12 (2021). doi: https://doi.org/10.3390/nu13124243
Zambrano E, Rodríguez-González GL, Reyes-Castro LA, Bautista CJ, Castro-Rodríguez DC, Juárez-Pilares G, Ibáñez CA, Hernández-Rojas A, Nathanielsz PW, Montaño S, Arredondo A, Huang F, Bolaños-Jiménez F. DHA Supplementation of Obese Rats throughout Pregnancy and Lactation Modifies Milk Composition and Anxiety Behavior of Offspring. Nutrients. 2021 Nov 26;13(12). doi: 10.3390/nu13124243. PMID: 34959795; PMCID: PMC8706754.
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Summary and Assessment of Studies on Cardiac Aging in Nonhuman Primates.

Comparative medicine

Huber HF, Nathanielsz PW, Clarke GD.
PMID: 34711301
Comp Med. 2021 Oct 28; doi: 10.30802/AALAS-CM-21-000038. Epub 2021 Oct 28.

Nonhuman primates (NHP) are important translational models for cardiac aging. To assess progress in this research area and to provide a reference for other investigators, we identified papers indexed in PubMed to determine what species, ages, outcomes, treatments, and...

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Huber HF, Nathanielsz PW, Clarke GD. Summary and Assessment of Studies on Cardiac Aging in Nonhuman Primates. Comp Med. 2021;doi: 10.30802/AALAS-CM-21-000038.
Huber, H. F., Nathanielsz, P. W., & Clarke, G. D. (2021). Summary and Assessment of Studies on Cardiac Aging in Nonhuman Primates. Comparative medicine, . https://doi.org/10.30802/AALAS-CM-21-000038
Huber, Hillary F, et al. "Summary and Assessment of Studies on Cardiac Aging in Nonhuman Primates." Comparative medicine vol. (2021). doi: https://doi.org/10.30802/AALAS-CM-21-000038
Huber HF, Nathanielsz PW, Clarke GD. Summary and Assessment of Studies on Cardiac Aging in Nonhuman Primates. Comp Med. 2021 Oct 28; doi: 10.30802/AALAS-CM-21-000038. Epub 2021 Oct 28. PMID: 34711301.
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Perinatal maternal undernutrition does not result in offspring capillary rarefaction in the middle-aged male baboon at rest.

Journal of developmental origins of health and disease

Kuo AH, Li C, Huber HF, Nathanielsz PW, Clarke GD.
PMID: 32618548
J Dev Orig Health Dis. 2021 Jun;12(3):349-353. doi: 10.1017/S2040174420000550. Epub 2020 Jun 19.

Microvascular health is a main determinant of coronary blood flow reserve and myocardial vascular resistance. Extracardiac capillary abnormality has been reported in subjects at increased coronary heart disease risk, such as prehypertension, hypertension, diabetes, hyperlipidemia, and atherosclerosis. We have...

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Kuo AH, Li C, Huber HF, et al. Perinatal maternal undernutrition does not result in offspring capillary rarefaction in the middle-aged male baboon at rest. J Dev Orig Health Dis. 2020;12(3):349-353doi: 10.1017/S2040174420000550.
Kuo, A. H., Li, C., Huber, H. F., Nathanielsz, P. W., & Clarke, G. D. (2021). Perinatal maternal undernutrition does not result in offspring capillary rarefaction in the middle-aged male baboon at rest. Journal of developmental origins of health and disease, 12(3), 349-353. https://doi.org/10.1017/S2040174420000550
Kuo, Anderson H, et al. "Perinatal maternal undernutrition does not result in offspring capillary rarefaction in the middle-aged male baboon at rest." Journal of developmental origins of health and disease vol. 12,3 (2021): 349-353. doi: https://doi.org/10.1017/S2040174420000550
Kuo AH, Li C, Huber HF, Nathanielsz PW, Clarke GD. Perinatal maternal undernutrition does not result in offspring capillary rarefaction in the middle-aged male baboon at rest. J Dev Orig Health Dis. 2021 Jun;12(3):349-353. doi: 10.1017/S2040174420000550. Epub 2020 Jun 19. PMID: 32618548; PMCID: PMC7748997.
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Hypothalamic expression of genes for appetite regulators and estrogen α, estrogen β and leptin receptors in obese dams and their fetuses.

Animal : an international journal of animal bioscience

Breton AB, Cockrum RR, Austin KJ, Cammack KM, Ford SP, Hess BW, Moss GE, Nathanielsz PW, Alexander BM.
PMID: 22440471
Animal. 2011 Dec;5(12):1944-8. doi: 10.1017/S1751731111001054.

Under- and over-nutrition during gestation may influence fetal hypothalamic development resulting in individuals predisposed to adverse health effects. This study examined fetuses from obese and control ewes to determine whether dam obesity alters hypothalamic expression of fetal appetite regulatory...

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Breton AB, Cockrum RR, Austin KJ, et al. Hypothalamic expression of genes for appetite regulators and estrogen α, estrogen β and leptin receptors in obese dams and their fetuses. Animal. 2011;5(12):1944-8doi: 10.1017/S1751731111001054.
Breton, A. B., Cockrum, R. R., Austin, K. J., Cammack, K. M., Ford, S. P., Hess, B. W., Moss, G. E., Nathanielsz, P. W., & Alexander, B. M. (2011). Hypothalamic expression of genes for appetite regulators and estrogen α, estrogen β and leptin receptors in obese dams and their fetuses. Animal : an international journal of animal bioscience, 5(12), 1944-8. https://doi.org/10.1017/S1751731111001054
Breton, A B, et al. "Hypothalamic expression of genes for appetite regulators and estrogen α, estrogen β and leptin receptors in obese dams and their fetuses." Animal : an international journal of animal bioscience vol. 5,12 (2011): 1944-8. doi: https://doi.org/10.1017/S1751731111001054
Breton AB, Cockrum RR, Austin KJ, Cammack KM, Ford SP, Hess BW, Moss GE, Nathanielsz PW, Alexander BM. Hypothalamic expression of genes for appetite regulators and estrogen α, estrogen β and leptin receptors in obese dams and their fetuses. Animal. 2011 Dec;5(12):1944-8. doi: 10.1017/S1751731111001054. PMID: 22440471.
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Maternal obesity disrupts the methionine cycle in baboon pregnancy.

Physiological reports

Nathanielsz PW, Yan J, Green R, Nijland M, Miller JW, Wu G, McDonald TJ, Caudill MA.
PMID: 26537341
Physiol Rep. 2015 Nov;3(11). doi: 10.14814/phy2.12564.

Maternal intake of dietary methyl-micronutrients (e.g. folate, choline, betaine and vitamin B-12) during pregnancy is essential for normal maternal and fetal methionine metabolism, and is critical for important metabolic processes including those involved in developmental programming. Maternal obesity and...

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Nathanielsz PW, Yan J, Green R, et al. Maternal obesity disrupts the methionine cycle in baboon pregnancy. Physiol Rep. 2015;3(11)doi: 10.14814/phy2.12564.
Nathanielsz, P. W., Yan, J., Green, R., Nijland, M., Miller, J. W., Wu, G., McDonald, T. J., & Caudill, M. A. (2015). Maternal obesity disrupts the methionine cycle in baboon pregnancy. Physiological reports, 3(11), . https://doi.org/10.14814/phy2.12564
Nathanielsz, Peter W, et al. "Maternal obesity disrupts the methionine cycle in baboon pregnancy." Physiological reports vol. 3,11 (2015). doi: https://doi.org/10.14814/phy2.12564
Nathanielsz PW, Yan J, Green R, Nijland M, Miller JW, Wu G, McDonald TJ, Caudill MA. Maternal obesity disrupts the methionine cycle in baboon pregnancy. Physiol Rep. 2015 Nov;3(11). doi: 10.14814/phy2.12564. PMID: 26537341; PMCID: PMC4673623.
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Summary and Assessment of Studies on Cardiac Aging in Nonhuman Primates.

Comparative medicine

Huber HF, Nathanielsz PW, Clarke GD.
PMID: 34711301
Comp Med. 2021 Dec 01;71(6):460-465. doi: 10.30802/AALAS-CM-21-000038. Epub 2021 Oct 28.

Nonhuman primates (NHP) are important translational models for cardiac aging. To assess progress in this research area and to provide a reference for other investigators, we identified papers indexed in PubMed to determine what species, ages, outcomes, treatments, and...

Cite
Huber HF, Nathanielsz PW, Clarke GD. Summary and Assessment of Studies on Cardiac Aging in Nonhuman Primates. Comp Med. 2021;71(6):460-465doi: 10.30802/AALAS-CM-21-000038.
Huber, H. F., Nathanielsz, P. W., & Clarke, G. D. (2021). Summary and Assessment of Studies on Cardiac Aging in Nonhuman Primates. Comparative medicine, 71(6), 460-465. https://doi.org/10.30802/AALAS-CM-21-000038
Huber, Hillary F, et al. "Summary and Assessment of Studies on Cardiac Aging in Nonhuman Primates." Comparative medicine vol. 71,6 (2021): 460-465. doi: https://doi.org/10.30802/AALAS-CM-21-000038
Huber HF, Nathanielsz PW, Clarke GD. Summary and Assessment of Studies on Cardiac Aging in Nonhuman Primates. Comp Med. 2021 Dec 01;71(6):460-465. doi: 10.30802/AALAS-CM-21-000038. Epub 2021 Oct 28. PMID: 34711301.
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Rodent studies of developmental programming and ageing mechanisms: Special issue: In utero and early life programming of ageing and disease.

European journal of clinical investigation

Zambrano E, Lomas-Soria C, Nathanielsz PW.
PMID: 34061987
Eur J Clin Invest. 2021 Oct;51(10):e13631. doi: 10.1111/eci.13631. Epub 2021 Jun 29.

Compelling evidence exists indicating that developmental programming influences ageing. Programming alters life-course phenotype in multiple organs, predisposing to diseases such as diabetes, obesity and cardiovascular disease that shorten lifespan. This review describes studies in rodents, the most commonly studied...

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Zambrano E, Lomas-Soria C, Nathanielsz PW. Rodent studies of developmental programming and ageing mechanisms: Special issue: In utero and early life programming of ageing and disease. Eur J Clin Invest. 2021;51(10):e13631doi: 10.1111/eci.13631.
Zambrano, E., Lomas-Soria, C., & Nathanielsz, P. W. (2021). Rodent studies of developmental programming and ageing mechanisms: Special issue: In utero and early life programming of ageing and disease. European journal of clinical investigation, 51(10), e13631. https://doi.org/10.1111/eci.13631
Zambrano, Elena, et al. "Rodent studies of developmental programming and ageing mechanisms: Special issue: In utero and early life programming of ageing and disease." European journal of clinical investigation vol. 51,10 (2021): e13631. doi: https://doi.org/10.1111/eci.13631
Zambrano E, Lomas-Soria C, Nathanielsz PW. Rodent studies of developmental programming and ageing mechanisms: Special issue: In utero and early life programming of ageing and disease. Eur J Clin Invest. 2021 Oct;51(10):e13631. doi: 10.1111/eci.13631. Epub 2021 Jun 29. PMID: 34061987.
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Developmental programming and ageing of male reproductive function.

European journal of clinical investigation

Zambrano E, Nathanielsz PW, Rodríguez-González GL.
PMID: 34107063
Eur J Clin Invest. 2021 Oct;51(10):e13637. doi: 10.1111/eci.13637. Epub 2021 Jun 26.

Developmental programming predisposes offspring to metabolic, behavioural and reproductive dysfunction in adult life. Evidence is accumulating that ageing phenotype and longevity are in part developmentally programmed in each individual. Unfortunately, there are few studies addressing the effects of developmental...

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Zambrano E, Nathanielsz PW, Rodríguez-González GL. Developmental programming and ageing of male reproductive function. Eur J Clin Invest. 2021;51(10):e13637doi: 10.1111/eci.13637.
Zambrano, E., Nathanielsz, P. W., & Rodríguez-González, G. L. (2021). Developmental programming and ageing of male reproductive function. European journal of clinical investigation, 51(10), e13637. https://doi.org/10.1111/eci.13637
Zambrano, Elena, et al. "Developmental programming and ageing of male reproductive function." European journal of clinical investigation vol. 51,10 (2021): e13637. doi: https://doi.org/10.1111/eci.13637
Zambrano E, Nathanielsz PW, Rodríguez-González GL. Developmental programming and ageing of male reproductive function. Eur J Clin Invest. 2021 Oct;51(10):e13637. doi: 10.1111/eci.13637. Epub 2021 Jun 26. PMID: 34107063.
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Showing 1 to 12 of 34 entries